JP2017536341A5 - - Google Patents

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Publication number
JP2017536341A5
JP2017536341A5 JP2017518516A JP2017518516A JP2017536341A5 JP 2017536341 A5 JP2017536341 A5 JP 2017536341A5 JP 2017518516 A JP2017518516 A JP 2017518516A JP 2017518516 A JP2017518516 A JP 2017518516A JP 2017536341 A5 JP2017536341 A5 JP 2017536341A5
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JP
Japan
Prior art keywords
antibody
ror1
domain
fab
bispecific antibody
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2017518516A
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English (en)
Japanese (ja)
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JP2017536341A (ja
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Publication date
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Priority claimed from PCT/EP2015/073309 external-priority patent/WO2016055593A1/en
Publication of JP2017536341A publication Critical patent/JP2017536341A/ja
Publication of JP2017536341A5 publication Critical patent/JP2017536341A5/ja
Pending legal-status Critical Current

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JP2017518516A 2014-10-09 2015-10-08 卵巣がんの処置における使用のためのCD3εおよびROR1に対する二特異性抗体 Pending JP2017536341A (ja)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
EP14188378.5 2014-10-09
EP14188378 2014-10-09
EP14188728 2014-10-14
EP14188728.1 2014-10-14
EP14188727 2014-10-14
EP14188727.3 2014-10-14
PCT/EP2015/073309 WO2016055593A1 (en) 2014-10-09 2015-10-08 Bispecific antibodies against cd3epsilon and ror1 for use in the treatment of ovarian cancer

Publications (2)

Publication Number Publication Date
JP2017536341A JP2017536341A (ja) 2017-12-07
JP2017536341A5 true JP2017536341A5 (OSRAM) 2018-11-22

Family

ID=54291293

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2017518516A Pending JP2017536341A (ja) 2014-10-09 2015-10-08 卵巣がんの処置における使用のためのCD3εおよびROR1に対する二特異性抗体

Country Status (6)

Country Link
US (1) US20170306044A1 (OSRAM)
EP (1) EP3204416A1 (OSRAM)
JP (1) JP2017536341A (OSRAM)
AU (1) AU2015329966A1 (OSRAM)
CA (1) CA2963696A1 (OSRAM)
WO (1) WO2016055593A1 (OSRAM)

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MA40972B1 (fr) 2014-11-20 2020-11-30 Hoffmann La Roche Molécules bispécifiques de liaison à l'antigène activant les lymphocytes t ciblant folr1 et cd3
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MA43025A (fr) 2015-10-02 2021-05-26 Hoffmann La Roche Molécules bispécifiques de liaison à l'antigène activant les lymphocytes t anti-ceaxcd3
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KR20180101554A (ko) 2016-01-20 2018-09-12 더 스크립스 리서치 인스티튜트 Ror1 항체 조성물 및 관련 방법
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EP3665193A1 (en) 2017-08-07 2020-06-17 NBE Therapeutics AG Anthracycline-based antibody drug conjugates having high in vivo tolerability
CN107827984B (zh) * 2017-09-13 2021-03-16 张慧林 嵌合抗ROR1抗体Fab分子及其制备方法和应用
GB201721802D0 (en) * 2017-12-22 2018-02-07 Almac Discovery Ltd Ror1-specific antigen binding molecules
CA3089287A1 (en) 2018-02-08 2019-08-15 Genentech, Inc. Bispecific antigen-binding molecules and methods of use
TWI829667B (zh) * 2018-02-09 2024-01-21 瑞士商赫孚孟拉羅股份公司 結合gprc5d之抗體
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TW202035451A (zh) 2018-07-24 2020-10-01 美商英伊布里克斯公司 含有受限cd3結合域及受體結合區之多重特異性多肽構築體及其使用方法
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BR112022014667A2 (pt) 2020-01-29 2022-09-20 Inhibrx Inc Anticorpos de domínio único de cd28 e construtos multivalentes e multiespecíficos dos mesmos
BR112022025856A2 (pt) 2020-06-19 2023-01-10 Hoffmann La Roche Anticorpo que se liga a cd3 e cd19, polinucleotídeo isolado, célula hospedeira, método de produção de um anticorpo que se liga a cd3 e cd19, composição farmacêutica, uso do anticorpo, método para tratar uma doença em um indivíduo e invenção
JP7781859B2 (ja) * 2020-08-24 2025-12-08 エピムアブ、バイオセラピューティクス、(ホンコン)、リミテッド 抗ror1抗体及び関連の二重特異性結合タンパク質
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KR20240005691A (ko) 2021-04-30 2024-01-12 에프. 호프만-라 로슈 아게 항-cd20/항-cd3 이중특이적 항체 및 항-cd79b 항체 약물 접합체를 이용한 병용 치료를 위한 투약
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CN104704004B (zh) * 2012-10-08 2019-12-31 罗切格利卡特公司 包含两个Fab片段的无Fc的抗体及使用方法
EA031214B1 (ru) * 2013-02-26 2018-12-28 Роше Гликарт Аг Биспецифические антигенсвязывающие молекулы, активирующие т-клетки
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EP2789630A1 (en) * 2013-04-09 2014-10-15 EngMab AG Bispecific antibodies against CD3e and ROR1

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