JP2017532378A5 - - Google Patents
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- JP2017532378A5 JP2017532378A5 JP2017538918A JP2017538918A JP2017532378A5 JP 2017532378 A5 JP2017532378 A5 JP 2017532378A5 JP 2017538918 A JP2017538918 A JP 2017538918A JP 2017538918 A JP2017538918 A JP 2017538918A JP 2017532378 A5 JP2017532378 A5 JP 2017532378A5
- Authority
- JP
- Japan
- Prior art keywords
- phospholipid
- polymer
- liposome composition
- aromatic
- patient
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201462061514P | 2014-10-08 | 2014-10-08 | |
| US62/061,514 | 2014-10-08 | ||
| US201562111057P | 2015-02-02 | 2015-02-02 | |
| US62/111,057 | 2015-02-02 | ||
| PCT/US2015/054732 WO2016057812A1 (en) | 2014-10-08 | 2015-10-08 | Mri imaging of amyloid plaque using liposomes |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2017532378A JP2017532378A (ja) | 2017-11-02 |
| JP2017532378A5 true JP2017532378A5 (cg-RX-API-DMAC7.html) | 2018-11-22 |
| JP6505235B2 JP6505235B2 (ja) | 2019-04-24 |
Family
ID=55653789
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017538918A Active JP6505235B2 (ja) | 2014-10-08 | 2015-10-08 | リポソームを用いるアミロイド斑のmriイメージング |
Country Status (10)
| Country | Link |
|---|---|
| US (4) | US9744251B2 (cg-RX-API-DMAC7.html) |
| EP (3) | EP3204051B1 (cg-RX-API-DMAC7.html) |
| JP (1) | JP6505235B2 (cg-RX-API-DMAC7.html) |
| KR (1) | KR102409017B1 (cg-RX-API-DMAC7.html) |
| CN (1) | CN107106708B (cg-RX-API-DMAC7.html) |
| AU (2) | AU2015330824A1 (cg-RX-API-DMAC7.html) |
| CA (1) | CA2963941C (cg-RX-API-DMAC7.html) |
| ES (2) | ES3032054T3 (cg-RX-API-DMAC7.html) |
| MX (1) | MX371295B (cg-RX-API-DMAC7.html) |
| WO (1) | WO2016057812A1 (cg-RX-API-DMAC7.html) |
Families Citing this family (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2012139080A2 (en) | 2011-04-06 | 2012-10-11 | Board Of Regents Of The University Of Texas System | Lipid-based nanoparticles |
| WO2013110013A1 (en) | 2012-01-20 | 2013-07-25 | Annapragada, Ananth | Methods and compositions for objectively characterizing medical images |
| MX371295B (es) | 2014-10-08 | 2020-01-24 | Texas Childrens Hospital | Formación de imágenes por irm de placas amiloides usando liposomas. |
| US10865207B2 (en) | 2016-07-22 | 2020-12-15 | Ac Immune S.A. | Compounds for imaging Tau protein aggregates |
| WO2018015549A1 (en) | 2016-07-22 | 2018-01-25 | Ac Immune S.A. | Compounds for imaging tau protein aggregates |
| EP3512570B1 (en) | 2016-09-16 | 2024-08-28 | Texas Children's Hospital | Liposomal gadolinium (gd) contrast agent for t1-mri |
| EP3548002B1 (en) * | 2016-11-30 | 2025-04-30 | Texas Children's Hospital | Hydrophilic fluorinated molecules for liposomal 19f mri probes with unique mr signatures |
| WO2019145291A1 (en) | 2018-01-24 | 2019-08-01 | Ac Immune Sa | Gamma-carboline compounds for the detection of tau aggregates |
| EP3743426A1 (en) | 2018-01-24 | 2020-12-02 | AC Immune SA | Azacarboline compounds for the detection of tau aggregates |
| US20210008204A1 (en) * | 2018-03-29 | 2021-01-14 | Microvascular Therapeutics LLC | Compositions and methods of detecting and treating alzheimer's disease |
| CA3102038A1 (en) | 2018-06-08 | 2019-12-12 | Ac Immune Sa | Novel compounds for diagnosis |
| US20200261605A1 (en) * | 2019-01-24 | 2020-08-20 | Alzeca Biosciences, LLC | Functionalized liposomes for imaging misfolded proteins |
| KR20220054288A (ko) * | 2019-07-08 | 2022-05-02 | 알제카 바이오사이언시스, 엘엘씨 | 타우 병리를 위한 표적화 리간드 |
| US11614451B2 (en) | 2019-07-08 | 2023-03-28 | Alzeca Biosciences, LLC | Targeting ligands for tau pathology |
| KR102546470B1 (ko) * | 2020-01-29 | 2023-06-21 | 텍사스 칠드런스 하스피탈 | 아밀로이드 침착의 mri용 표적 조영제 |
| US11779664B2 (en) | 2020-02-12 | 2023-10-10 | Texas Children's Hospital | Targeted contrast agents for MRI of alpha-synuclein deposition |
| JP2023514991A (ja) * | 2020-02-12 | 2023-04-12 | テキサス チルドレンズ ホスピタル | α-シンヌクレイン沈着物のMRIのための標的造影剤 |
| CN115970009A (zh) * | 2023-02-08 | 2023-04-18 | 丽水市中心医院 | Vhpk多肽修饰的荧光纳米脂质体给药系统、其制备方法及应用 |
| CN116869938A (zh) * | 2023-07-26 | 2023-10-13 | 安徽医科大学 | 一种1,2,4-噁二唑-吡啶脂质体及其制备方法和应用 |
Family Cites Families (35)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5204085A (en) | 1985-01-08 | 1993-04-20 | Mallinckrodt Medical, Inc. | Method for enhancing the safety of metal-ligand chelates as X-ray contrast agents |
| CA2185810A1 (en) | 1994-03-28 | 1995-10-05 | Jo Klaveness | Liposomes |
| US6071532A (en) | 1996-10-15 | 2000-06-06 | Emory University | Synthesis of glycophospholipid and peptide-phospholipid conjugates and uses thereof |
| ATE287700T1 (de) | 1999-11-30 | 2005-02-15 | Univ Arizona | Strahlung-sensitive liposomen |
| US7029655B2 (en) | 2000-10-04 | 2006-04-18 | California Institute Of Technology | Magnetic resonance imaging agents for in vivo labeling and detection of amyloid deposits |
| US6821504B2 (en) | 2001-05-23 | 2004-11-23 | New York University | Detection of alzheimer's amyloid by magnetic resonance imaging |
| JP2005519129A (ja) | 2002-03-05 | 2005-06-30 | クリーブランド ステート ユニバーシティー | エアロゾル薬物送達のための凝集粒子 |
| US7605182B2 (en) | 2003-05-01 | 2009-10-20 | Aposense Ltd. | Compounds that selectively bind to membranes of apoptotic cells |
| US7208174B2 (en) | 2003-12-18 | 2007-04-24 | Hoffmann-La Roche Inc. | Liposome compositions |
| US20100031378A1 (en) | 2008-08-04 | 2010-02-04 | Edwards Joel A | Novel gene disruptions, compositions and methods relating thereto |
| US8357351B2 (en) | 2004-04-21 | 2013-01-22 | Ananth Annapragada | Nano-scale contrast agents and methods of use |
| US7713517B2 (en) | 2004-04-21 | 2010-05-11 | Marval Biosciences, Inc. | Compositions and methods for enhancing contrast in imaging |
| ATE493152T1 (de) | 2004-09-23 | 2011-01-15 | Guerbet Sa | Liposomale kontrastmittel für die cest-bildgebung |
| CA2626005A1 (en) | 2005-10-13 | 2007-10-25 | Waratah Pharmaceuticals Inc. | Inositol derivatives and their uses in the treatment of diseases characterized by abnormal protein folding or aggregation or amyloid formation, deposition, accumulation or persistence |
| US20070160658A1 (en) | 2005-10-20 | 2007-07-12 | The Penn State Research Foundation | Delivery system for diagnostic and therapeutic agents |
| US20090123047A1 (en) | 2007-03-21 | 2009-05-14 | Yfantis Spyros A | Method and system for characterizing prostate images |
| EP1982733A1 (en) | 2007-04-17 | 2008-10-22 | Bayer Schering Pharma Aktiengesellschaft | Use of a contrast agent for magnetic resonance imaging of endoleaks |
| US7858803B2 (en) | 2007-04-27 | 2010-12-28 | The General Hospital Corporation | Imaging tracers for early detection and treatment of amyloid plaques caused by Alzheimer's disease and related disorders |
| WO2009015397A1 (en) | 2007-07-26 | 2009-01-29 | Nanoscan Imaging, Llc | Methods for imaging using improved nanoparticulate contrast agents |
| AU2008331764A1 (en) | 2007-12-05 | 2009-06-11 | Marval Biosciences, Inc. | Nano-scale contrast agents and methods of use |
| EP2242505A4 (en) | 2008-01-08 | 2012-03-07 | Biogenerix Ag | GLYCOCONJUGATION OF POLYPEPTIDES USING OLIGOSACCHARYLTRANSFERASES |
| ITMI20081052A1 (it) | 2008-06-10 | 2009-12-11 | Univ Milano Bicocca | Liposomi in grado di legare efficacemente il peptide beta-amiloide |
| WO2009152445A1 (en) | 2008-06-13 | 2009-12-17 | Marval Biosciences, Inc. | Imaging of atherosclerotic plaques using liposomal imaging agents |
| WO2010017094A2 (en) | 2008-07-31 | 2010-02-11 | The General Hospital Corporation | CURCUMIN DERIVATIVES FOR AMYLOID-β PLAQUE IMAGING |
| AR074760A1 (es) * | 2008-12-18 | 2011-02-09 | Metabolex Inc | Agonistas del receptor gpr120 y usos de los mismos en medicamentos para el tratamiento de diabetes y el sindrome metabolico. |
| JP2012520898A (ja) | 2009-03-19 | 2012-09-10 | マーヴァル バイオサイエンシーズ,インコーポレイテッド | 画像化におけるコントラスト強調のための組成物および方法 |
| EP2501696B1 (en) | 2009-10-15 | 2016-12-28 | Guerbet | Imaging agents and their use for the diagnostic in vivo of neurodegenerative diseases, notably alzheimer's disease and derivative diseases |
| ES2526124T3 (es) * | 2010-06-16 | 2015-01-07 | Cymabay Therapeutics, Inc. | Agonistas del receptor GPR120 y sus usos |
| JP5998158B2 (ja) | 2011-03-02 | 2016-09-28 | センスリン,エルエルシー | ベシクル組成物 |
| WO2012139080A2 (en) * | 2011-04-06 | 2012-10-11 | Board Of Regents Of The University Of Texas System | Lipid-based nanoparticles |
| GB201112056D0 (en) | 2011-07-14 | 2011-08-31 | Univ Leuven Kath | Antibodies |
| WO2013110013A1 (en) | 2012-01-20 | 2013-07-25 | Annapragada, Ananth | Methods and compositions for objectively characterizing medical images |
| WO2013164763A2 (en) | 2012-04-30 | 2013-11-07 | Innovative Health Diagnostics | A biological complex specific for alzheimer's disease detection in vitro and use thereof |
| AU2014240042C1 (en) * | 2013-03-14 | 2019-09-05 | Celltaxis, Llc | Inhibitors of leukotriene A4 hydrolase |
| MX371295B (es) | 2014-10-08 | 2020-01-24 | Texas Childrens Hospital | Formación de imágenes por irm de placas amiloides usando liposomas. |
-
2015
- 2015-10-08 MX MX2017004695A patent/MX371295B/es active IP Right Grant
- 2015-10-08 EP EP15849750.3A patent/EP3204051B1/en active Active
- 2015-10-08 ES ES22152987T patent/ES3032054T3/es active Active
- 2015-10-08 WO PCT/US2015/054732 patent/WO2016057812A1/en not_active Ceased
- 2015-10-08 US US14/878,745 patent/US9744251B2/en active Active
- 2015-10-08 CA CA2963941A patent/CA2963941C/en active Active
- 2015-10-08 EP EP22152987.8A patent/EP4035688B1/en active Active
- 2015-10-08 EP EP19172751.0A patent/EP3542828A1/en not_active Withdrawn
- 2015-10-08 AU AU2015330824A patent/AU2015330824A1/en not_active Abandoned
- 2015-10-08 KR KR1020177012354A patent/KR102409017B1/ko active Active
- 2015-10-08 ES ES15849750T patent/ES2743704T3/es active Active
- 2015-10-08 CN CN201580066712.6A patent/CN107106708B/zh active Active
- 2015-10-08 JP JP2017538918A patent/JP6505235B2/ja active Active
-
2016
- 2016-12-01 US US15/366,667 patent/US10537649B2/en active Active
-
2019
- 2019-11-08 US US16/677,751 patent/US20200069820A1/en not_active Abandoned
-
2020
- 2020-02-14 US US16/791,068 patent/US11141495B2/en active Active
-
2021
- 2021-05-25 AU AU2021203388A patent/AU2021203388B2/en active Active
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