JP2017530959A5 - - Google Patents

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Publication number
JP2017530959A5
JP2017530959A5 JP2017514627A JP2017514627A JP2017530959A5 JP 2017530959 A5 JP2017530959 A5 JP 2017530959A5 JP 2017514627 A JP2017514627 A JP 2017514627A JP 2017514627 A JP2017514627 A JP 2017514627A JP 2017530959 A5 JP2017530959 A5 JP 2017530959A5
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JP
Japan
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unsubstituted
substituted
alkyl
haloalkyl
hydrogen
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JP2017514627A
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English (en)
Japanese (ja)
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JP2017530959A (ja
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Priority claimed from PCT/US2015/050712 external-priority patent/WO2016044604A1/en
Publication of JP2017530959A publication Critical patent/JP2017530959A/ja
Publication of JP2017530959A5 publication Critical patent/JP2017530959A5/ja
Withdrawn legal-status Critical Current

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JP2017514627A 2014-09-17 2015-09-17 Carm1阻害剤およびその使用 Withdrawn JP2017530959A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201462051872P 2014-09-17 2014-09-17
US62/051,872 2014-09-17
PCT/US2015/050712 WO2016044604A1 (en) 2014-09-17 2015-09-17 Carm1 inhibitors and uses thereof

Publications (2)

Publication Number Publication Date
JP2017530959A JP2017530959A (ja) 2017-10-19
JP2017530959A5 true JP2017530959A5 (show.php) 2018-11-01

Family

ID=55533856

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2017514627A Withdrawn JP2017530959A (ja) 2014-09-17 2015-09-17 Carm1阻害剤およびその使用

Country Status (4)

Country Link
US (1) US20170305922A1 (show.php)
EP (1) EP3193608A4 (show.php)
JP (1) JP2017530959A (show.php)
WO (1) WO2016044604A1 (show.php)

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WO2014153208A1 (en) 2013-03-14 2014-09-25 Epizyme, Inc. Arginine methyltransferase inhibitors and uses thereof
US9776972B2 (en) 2013-03-14 2017-10-03 Epizyme Inc. Pyrazole derivatives as arginine methyltransferase inhibitors and uses thereof
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WO2014153214A1 (en) 2013-03-14 2014-09-25 Epizyme, Inc. Arginine methyl transferase inhibtors and uses thereof
EA201591532A1 (ru) 2013-03-15 2016-03-31 Эпизим, Инк. Ингибиторы carm1 и их применение
US9718816B2 (en) 2013-03-15 2017-08-01 Epizyme, Inc. 1-phenoxy-3-(alkylamino)-propan-2-ol derivatives as CARM1 inhibitors and uses thereof
TWI659021B (zh) 2013-10-10 2019-05-11 亞瑞克西斯製藥公司 Kras g12c之抑制劑
JP2017530940A (ja) 2014-08-04 2017-10-19 エピザイム,インコーポレイティド Prmt5阻害剤およびその使用
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EP3558973B1 (en) 2016-12-22 2021-09-15 Incyte Corporation Pyridine derivatives as immunomodulators
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PE20191532A1 (es) 2016-12-22 2019-10-23 Incyte Corp Compuestos heterociclicos como inmunomoduladores
TW201835049A (zh) 2016-12-22 2018-10-01 美商英塞特公司 作為免疫調節劑之雜環化合物
JP7327802B2 (ja) 2017-01-26 2023-08-16 アラクセス ファーマ エルエルシー 縮合ヘテロ-ヘテロ二環式化合物およびその使用方法
US11358959B2 (en) 2017-01-26 2022-06-14 Araxes Pharma Llc Benzothiophene and benzothiazole compounds and methods of use thereof
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US11274093B2 (en) 2017-01-26 2022-03-15 Araxes Pharma Llc Fused bicyclic benzoheteroaromatic compounds and methods of use thereof
EP3573971A1 (en) 2017-01-26 2019-12-04 Araxes Pharma LLC 1-(3-(6-(3-hydroxynaphthalen-1-yl)benzofuran-2-yl)azetidin-1yl)prop-2-en-1-one derivatives and similar compounds as kras g12c modulators for treating cancer
US11014927B2 (en) 2017-03-20 2021-05-25 Forma Therapeutics, Inc. Pyrrolopyrrole compositions as pyruvate kinase (PKR) activators
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CA3107168A1 (en) * 2018-08-01 2020-02-06 Araxes Pharma Llc Heterocyclic spiro compounds and methods of use thereof for the treatment of cancer
JP7450610B2 (ja) 2018-09-19 2024-03-15 ノヴォ・ノルディスク・ヘルス・ケア・アーゲー ピルビン酸キナーゼrの活性化
MA53668B1 (fr) 2018-09-19 2024-06-28 Novo Nordisk Health Care Ag Traitement de la drépanocytose avec un composé activant la pyruvate kinase r
CA3144344A1 (en) 2019-06-28 2020-12-30 Als Therapy Development Institute Inhibition of dipeptide repeat proteins
TW202115059A (zh) 2019-08-09 2021-04-16 美商英塞特公司 Pd—1/pd—l1抑制劑之鹽
MA57202B1 (fr) 2019-09-19 2025-09-30 Novo Nordisk Health Care Ag Compositions d'activation de la pyruvate kinase r (pkr)
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WO2008104077A1 (en) * 2007-02-28 2008-09-04 Methylgene Inc. Small molecule inhibitors of protein arginine methyltransferases (prmts)
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US10118918B2 (en) * 2012-12-21 2018-11-06 Epizyme, Inc. PRMT5 inhibitors and uses thereof
EA201591532A1 (ru) * 2013-03-15 2016-03-31 Эпизим, Инк. Ингибиторы carm1 и их применение
WO2016044641A2 (en) * 2014-09-17 2016-03-24 Epizyme, Inc. Carm1 inhibitors and uses thereof

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