|
EP2935243B1
(en)
|
2012-12-21 |
2018-03-14 |
Epizyme, Inc. |
Prmt5 inhibitors containing a dihydro- or tetrahydroisoquinoline and uses thereof
|
|
LT2935222T
(lt)
|
2012-12-21 |
2018-12-27 |
Epizyme, Inc. |
Prmt5 slopikliai ir jų panaudojimas
|
|
US9365555B2
(en)
|
2012-12-21 |
2016-06-14 |
Epizyme, Inc. |
PRMT5 inhibitors and uses thereof
|
|
US10118918B2
(en)
|
2012-12-21 |
2018-11-06 |
Epizyme, Inc. |
PRMT5 inhibitors and uses thereof
|
|
CA2894126A1
(en)
|
2012-12-21 |
2014-06-26 |
Epizyme, Inc. |
Prmt5 inhibitors and uses thereof
|
|
US9120757B2
(en)
|
2013-03-14 |
2015-09-01 |
Epizyme, Inc. |
Arginine methyltransferase inhibitors and uses thereof
|
|
US9023883B2
(en)
|
2013-03-14 |
2015-05-05 |
Epizyme, Inc. |
PRMT1 inhibitors and uses thereof
|
|
WO2014153208A1
(en)
|
2013-03-14 |
2014-09-25 |
Epizyme, Inc. |
Arginine methyltransferase inhibitors and uses thereof
|
|
US9776972B2
(en)
|
2013-03-14 |
2017-10-03 |
Epizyme Inc. |
Pyrazole derivatives as arginine methyltransferase inhibitors and uses thereof
|
|
EA030481B1
(ru)
|
2013-03-14 |
2018-08-31 |
Эпизим, Инк. |
Ингибиторы аргининметилтрансферазы и их применения
|
|
WO2014153214A1
(en)
|
2013-03-14 |
2014-09-25 |
Epizyme, Inc. |
Arginine methyl transferase inhibtors and uses thereof
|
|
EA201591532A1
(ru)
|
2013-03-15 |
2016-03-31 |
Эпизим, Инк. |
Ингибиторы carm1 и их применение
|
|
US9718816B2
(en)
|
2013-03-15 |
2017-08-01 |
Epizyme, Inc. |
1-phenoxy-3-(alkylamino)-propan-2-ol derivatives as CARM1 inhibitors and uses thereof
|
|
TWI659021B
(zh)
|
2013-10-10 |
2019-05-11 |
亞瑞克西斯製藥公司 |
Kras g12c之抑制劑
|
|
JP2017530940A
(ja)
|
2014-08-04 |
2017-10-19 |
エピザイム,インコーポレイティド |
Prmt5阻害剤およびその使用
|
|
ES2928164T3
(es)
|
2015-10-19 |
2022-11-15 |
Incyte Corp |
Compuestos heterocíclicos como inmunomoduladores
|
|
ES2928856T3
(es)
|
2015-11-19 |
2022-11-23 |
Incyte Corp |
Compuestos heterocíclicos como inmunomoduladores
|
|
TW201726623A
(zh)
|
2015-12-17 |
2017-08-01 |
英塞特公司 |
作為免疫調節劑之雜環化合物
|
|
EP3394033B1
(en)
|
2015-12-22 |
2020-11-25 |
Incyte Corporation |
Heterocyclic compounds as immunomodulators
|
|
ES2906460T3
(es)
|
2016-05-06 |
2022-04-18 |
Incyte Corp |
Compuestos heterocíclicos como inmunomoduladores
|
|
EP3464279B1
(en)
|
2016-05-26 |
2021-11-24 |
Incyte Corporation |
Heterocyclic compounds as immunomodulators
|
|
CA3028685A1
(en)
|
2016-06-20 |
2017-12-28 |
Incyte Corporation |
Heterocyclic compounds as immunomodulators
|
|
WO2018013789A1
(en)
|
2016-07-14 |
2018-01-18 |
Incyte Corporation |
Heterocyclic compounds as immunomodulators
|
|
WO2018044783A1
(en)
|
2016-08-29 |
2018-03-08 |
Incyte Corporation |
Heterocyclic compounds as immunomodulators
|
|
JP7231226B2
(ja)
|
2016-11-07 |
2023-03-01 |
ユニバーシティ オブ マサチューセッツ |
顔面肩甲上腕型筋ジストロフィーのための治療標的
|
|
MX391980B
(es)
|
2016-12-22 |
2025-03-21 |
Incyte Corp |
Derivados de tetrahidro imidazo [4,5-c] piridina como inductores de internalización de ligando 1 de muerte programada (pd-l1).
|
|
EP3558973B1
(en)
|
2016-12-22 |
2021-09-15 |
Incyte Corporation |
Pyridine derivatives as immunomodulators
|
|
ES2874756T3
(es)
|
2016-12-22 |
2021-11-05 |
Incyte Corp |
Derivados de triazolo[1,5-A]piridina como inmunomoduladores
|
|
PE20191532A1
(es)
|
2016-12-22 |
2019-10-23 |
Incyte Corp |
Compuestos heterociclicos como inmunomoduladores
|
|
TW201835049A
(zh)
|
2016-12-22 |
2018-10-01 |
美商英塞特公司 |
作為免疫調節劑之雜環化合物
|
|
JP7327802B2
(ja)
|
2017-01-26 |
2023-08-16 |
アラクセス ファーマ エルエルシー |
縮合ヘテロ-ヘテロ二環式化合物およびその使用方法
|
|
US11358959B2
(en)
|
2017-01-26 |
2022-06-14 |
Araxes Pharma Llc |
Benzothiophene and benzothiazole compounds and methods of use thereof
|
|
WO2018140514A1
(en)
|
2017-01-26 |
2018-08-02 |
Araxes Pharma Llc |
1-(6-(3-hydroxynaphthalen-1-yl)quinazolin-2-yl)azetidin-1-yl)prop-2-en-1-one derivatives and similar compounds as kras g12c inhibitors for the treatment of cancer
|
|
US11274093B2
(en)
|
2017-01-26 |
2022-03-15 |
Araxes Pharma Llc |
Fused bicyclic benzoheteroaromatic compounds and methods of use thereof
|
|
EP3573971A1
(en)
|
2017-01-26 |
2019-12-04 |
Araxes Pharma LLC |
1-(3-(6-(3-hydroxynaphthalen-1-yl)benzofuran-2-yl)azetidin-1yl)prop-2-en-1-one derivatives and similar compounds as kras g12c modulators for treating cancer
|
|
US11014927B2
(en)
|
2017-03-20 |
2021-05-25 |
Forma Therapeutics, Inc. |
Pyrrolopyrrole compositions as pyruvate kinase (PKR) activators
|
|
EP3630747A1
(en)
|
2017-05-25 |
2020-04-08 |
Araxes Pharma LLC |
Quinazoline derivatives as modulators of mutant kras, hras or nras
|
|
AU2018271990A1
(en)
|
2017-05-25 |
2019-12-12 |
Araxes Pharma Llc |
Covalent inhibitors of KRAS
|
|
IL313101A
(en)
|
2018-03-30 |
2024-07-01 |
Incyte Corp |
Heterocyclic compounds as immunomodulators
|
|
MD3790877T2
(ro)
|
2018-05-11 |
2023-08-31 |
Incyte Corp |
Derivați de tetrahidro-imidazo[4,5-c]piridină în calitate de imunomodulatori PD-L1
|
|
CA3107168A1
(en)
*
|
2018-08-01 |
2020-02-06 |
Araxes Pharma Llc |
Heterocyclic spiro compounds and methods of use thereof for the treatment of cancer
|
|
JP7450610B2
(ja)
|
2018-09-19 |
2024-03-15 |
ノヴォ・ノルディスク・ヘルス・ケア・アーゲー |
ピルビン酸キナーゼrの活性化
|
|
MA53668B1
(fr)
|
2018-09-19 |
2024-06-28 |
Novo Nordisk Health Care Ag |
Traitement de la drépanocytose avec un composé activant la pyruvate kinase r
|
|
CA3144344A1
(en)
|
2019-06-28 |
2020-12-30 |
Als Therapy Development Institute |
Inhibition of dipeptide repeat proteins
|
|
TW202115059A
(zh)
|
2019-08-09 |
2021-04-16 |
美商英塞特公司 |
Pd—1/pd—l1抑制劑之鹽
|
|
MA57202B1
(fr)
|
2019-09-19 |
2025-09-30 |
Novo Nordisk Health Care Ag |
Compositions d'activation de la pyruvate kinase r (pkr)
|
|
JP7559059B2
(ja)
|
2019-09-30 |
2024-10-01 |
インサイト・コーポレイション |
免疫調節剤としてのピリド[3,2-d]ピリミジン化合物
|
|
WO2021096849A1
(en)
|
2019-11-11 |
2021-05-20 |
Incyte Corporation |
Salts and crystalline forms of a pd-1/pd-l1 inhibitor
|
|
WO2021188828A1
(en)
*
|
2020-03-18 |
2021-09-23 |
Dana-Farber Cancer Institute, Inc. |
Methods for treating cancer by inhibiting carm1
|
|
US11780836B2
(en)
|
2020-11-06 |
2023-10-10 |
Incyte Corporation |
Process of preparing a PD-1/PD-L1 inhibitor
|
|
TW202233615A
(zh)
|
2020-11-06 |
2022-09-01 |
美商英塞特公司 |
Pd—1/pd—l1抑制劑之結晶形式
|
|
JP2023548859A
(ja)
|
2020-11-06 |
2023-11-21 |
インサイト・コーポレイション |
Pd-1/pd-l1阻害剤ならびにその塩及び結晶形態を作製するためのプロセス
|
|
US12128035B2
(en)
|
2021-03-19 |
2024-10-29 |
Novo Nordisk Health Care Ag |
Activating pyruvate kinase R
|