JP2017529066A5 - - Google Patents
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- Publication number
- JP2017529066A5 JP2017529066A5 JP2017506339A JP2017506339A JP2017529066A5 JP 2017529066 A5 JP2017529066 A5 JP 2017529066A5 JP 2017506339 A JP2017506339 A JP 2017506339A JP 2017506339 A JP2017506339 A JP 2017506339A JP 2017529066 A5 JP2017529066 A5 JP 2017529066A5
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- JP
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- Prior art keywords
- cells
- nerve
- population
- optionally
- embryonic
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
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- 210000004027 cell Anatomy 0.000 claims 22
- 210000000578 peripheral nerve Anatomy 0.000 claims 19
- 238000000034 method Methods 0.000 claims 12
- 230000004069 differentiation Effects 0.000 claims 11
- 238000012258 culturing Methods 0.000 claims 10
- 208000014674 injury Diseases 0.000 claims 9
- 102100024506 Bone morphogenetic protein 2 Human genes 0.000 claims 8
- 101000762366 Homo sapiens Bone morphogenetic protein 2 Proteins 0.000 claims 8
- 210000005036 nerve Anatomy 0.000 claims 8
- 230000008733 trauma Effects 0.000 claims 7
- 230000010261 cell growth Effects 0.000 claims 5
- 108700021430 Kruppel-Like Factor 4 Proteins 0.000 claims 4
- 101710135898 Myc proto-oncogene protein Proteins 0.000 claims 4
- 102100038895 Myc proto-oncogene protein Human genes 0.000 claims 4
- 101710126211 POU domain, class 5, transcription factor 1 Proteins 0.000 claims 4
- 101100247004 Rattus norvegicus Qsox1 gene Proteins 0.000 claims 4
- 101710150448 Transcriptional regulator Myc Proteins 0.000 claims 4
- 238000001727 in vivo Methods 0.000 claims 3
- 210000001178 neural stem cell Anatomy 0.000 claims 3
- 210000001778 pluripotent stem cell Anatomy 0.000 claims 3
- 208000027418 Wounds and injury Diseases 0.000 claims 2
- 230000006378 damage Effects 0.000 claims 2
- 210000004039 endoderm cell Anatomy 0.000 claims 2
- 210000002889 endothelial cell Anatomy 0.000 claims 2
- 210000000245 forearm Anatomy 0.000 claims 2
- 210000001704 mesoblast Anatomy 0.000 claims 2
- 210000000963 osteoblast Anatomy 0.000 claims 2
- 230000035939 shock Effects 0.000 claims 2
- 230000000638 stimulation Effects 0.000 claims 2
- 210000001590 sural nerve Anatomy 0.000 claims 2
- 102000029816 Collagenase Human genes 0.000 claims 1
- 108060005980 Collagenase Proteins 0.000 claims 1
- 102000002274 Matrix Metalloproteinases Human genes 0.000 claims 1
- 108010000684 Matrix Metalloproteinases Proteins 0.000 claims 1
- 208000009893 Nonpenetrating Wounds Diseases 0.000 claims 1
- 108091005804 Peptidases Proteins 0.000 claims 1
- 239000004365 Protease Substances 0.000 claims 1
- 102100037486 Reverse transcriptase/ribonuclease H Human genes 0.000 claims 1
- 210000004504 adult stem cell Anatomy 0.000 claims 1
- 230000024245 cell differentiation Effects 0.000 claims 1
- 229960002424 collagenase Drugs 0.000 claims 1
- 230000006835 compression Effects 0.000 claims 1
- 238000007906 compression Methods 0.000 claims 1
- 210000003981 ectoderm Anatomy 0.000 claims 1
- 210000001900 endoderm Anatomy 0.000 claims 1
- 230000009762 endothelial cell differentiation Effects 0.000 claims 1
- 210000003414 extremity Anatomy 0.000 claims 1
- 238000001415 gene therapy Methods 0.000 claims 1
- 239000011521 glass Substances 0.000 claims 1
- 230000003601 intercostal effect Effects 0.000 claims 1
- 238000010255 intramuscular injection Methods 0.000 claims 1
- 239000007927 intramuscular injection Substances 0.000 claims 1
- 238000004519 manufacturing process Methods 0.000 claims 1
- 210000003716 mesoderm Anatomy 0.000 claims 1
- 230000004899 motility Effects 0.000 claims 1
- 210000003205 muscle Anatomy 0.000 claims 1
- 230000001537 neural effect Effects 0.000 claims 1
- 230000009818 osteogenic differentiation Effects 0.000 claims 1
- 239000000758 substrate Substances 0.000 claims 1
- 230000003685 thermal hair damage Effects 0.000 claims 1
- 230000017423 tissue regeneration Effects 0.000 claims 1
- 210000003371 toe Anatomy 0.000 claims 1
- 230000000472 traumatic effect Effects 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201462032911P | 2014-08-04 | 2014-08-04 | |
| US62/032,911 | 2014-08-04 | ||
| PCT/US2015/043424 WO2016022472A1 (en) | 2014-08-04 | 2015-08-03 | Mammalian pluripotent stem cells, methods for their production, and uses thereof |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2017529066A JP2017529066A (ja) | 2017-10-05 |
| JP2017529066A5 true JP2017529066A5 (enExample) | 2018-09-13 |
| JP6698626B2 JP6698626B2 (ja) | 2020-05-27 |
Family
ID=55178918
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017506339A Expired - Fee Related JP6698626B2 (ja) | 2014-08-04 | 2015-08-03 | 哺乳動物多能性幹細胞、それらの調製のための方法、およびその使用 |
Country Status (7)
| Country | Link |
|---|---|
| US (2) | US20160030484A1 (enExample) |
| EP (1) | EP3194573A4 (enExample) |
| JP (1) | JP6698626B2 (enExample) |
| CN (1) | CN106687582A (enExample) |
| AU (1) | AU2015301342A1 (enExample) |
| CA (1) | CA2957071A1 (enExample) |
| WO (1) | WO2016022472A1 (enExample) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP6698626B2 (ja) * | 2014-08-04 | 2020-05-27 | ユニバーシティ・オブ・カンザス | 哺乳動物多能性幹細胞、それらの調製のための方法、およびその使用 |
| CN106222133A (zh) * | 2016-06-29 | 2016-12-14 | 湛江经济技术开发区海滨医疗器械有限公司 | 一种利用冲击波使人体间充质干细胞增殖的方法 |
| CN109280682B (zh) * | 2018-08-31 | 2025-09-09 | 华子昂 | 增强血管内皮细胞表达p选择素的方法 |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20030003572A1 (en) * | 1999-03-05 | 2003-01-02 | David J. Anderson | Isolation and enrichment of neural stem cells from uncultured tissue based on cell-surface marker expression |
| ES2690554T3 (es) * | 2008-03-17 | 2018-11-21 | The Scripps Research Institute | Enfoques químicos y genéticos combinados para la generación de células madre pluripotentes inducidas |
| EP2128245A1 (en) | 2008-05-27 | 2009-12-02 | Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. | Generation of induced pluripotent stem (iPS) cells |
| CN101492676B (zh) * | 2008-09-16 | 2011-02-16 | 中国科学院广州生物医药与健康研究院 | 用脑膜细胞生成诱导的多能性干细胞的方法及其用途 |
| KR20110134939A (ko) * | 2009-04-03 | 2011-12-15 | 더 맥클린 하스피털 코퍼레이션 | 유도된 다능성 줄기 세포 |
| US8193235B2 (en) * | 2009-06-12 | 2012-06-05 | University Of Kansas | Compositions and methods for establishing and maintaining stem cells in an undifferentiated state |
| WO2011013806A1 (ja) * | 2009-07-30 | 2011-02-03 | 学校法人慶應義塾 | シュワン前駆細胞の製造方法及び増殖方法 |
| CN102725399B (zh) | 2009-12-18 | 2015-03-11 | 上海赛傲生物技术有限公司 | 制备多能干细胞的材料和方法 |
| EP2537922B1 (en) * | 2010-02-18 | 2021-04-21 | Kang Stem Biotech Co., Ltd. | Cd49f promoting proliferation, multipotency and reprogramming of adult stem cells through pi3k/akt/gsk3 pathway |
| WO2011108766A1 (en) * | 2010-03-03 | 2011-09-09 | Kyoto University | METHOD FOR DIAGNOSING A PROTEIN MISFOLDING DISEASE USING NERVE CELLS DERIVED FROM iPS CELLS |
| CN102191221B (zh) * | 2010-03-17 | 2014-11-19 | 中国人民解放军第二军医大学东方肝胆外科医院 | 一种能无限自我更新的神经干细胞、其制备方法及其用途 |
| US20120069782A1 (en) * | 2010-09-22 | 2012-03-22 | Richard Lee-Chee Kuo | Method and apparatus for improving drx in a wireless communication system |
| US20150159135A1 (en) * | 2012-06-15 | 2015-06-11 | Baylor College Of Medicine | Perineurium Derived Adult Stem Cells and Methods of Use |
| JP6698626B2 (ja) * | 2014-08-04 | 2020-05-27 | ユニバーシティ・オブ・カンザス | 哺乳動物多能性幹細胞、それらの調製のための方法、およびその使用 |
-
2015
- 2015-08-03 JP JP2017506339A patent/JP6698626B2/ja not_active Expired - Fee Related
- 2015-08-03 US US14/816,661 patent/US20160030484A1/en not_active Abandoned
- 2015-08-03 AU AU2015301342A patent/AU2015301342A1/en not_active Abandoned
- 2015-08-03 CN CN201580050219.5A patent/CN106687582A/zh active Pending
- 2015-08-03 CA CA2957071A patent/CA2957071A1/en not_active Abandoned
- 2015-08-03 EP EP15829472.8A patent/EP3194573A4/en not_active Withdrawn
- 2015-08-03 WO PCT/US2015/043424 patent/WO2016022472A1/en not_active Ceased
-
2019
- 2019-04-04 US US16/375,006 patent/US10787658B2/en active Active
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