JP2017528465A - 乾癬性関節炎患者における構造的損傷の進行を阻害するためのｉｌ−１７アンタゴニストの使用 - Google Patents

乾癬性関節炎患者における構造的損傷の進行を阻害するためのｉｌ−１７アンタゴニストの使用 Download PDF

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JP2017528465A
JP2017528465A JP2017513409A JP2017513409A JP2017528465A JP 2017528465 A JP2017528465 A JP 2017528465A JP 2017513409 A JP2017513409 A JP 2017513409A JP 2017513409 A JP2017513409 A JP 2017513409A JP 2017528465 A JP2017528465 A JP 2017528465A
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seq
patient
secukinumab
antibody
antagonist
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JP2017528465A5 (cg-RX-API-DMAC7.html
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ムポフ，ステファ−ド
リチャーズ，ハノ
リゴズィオ，グレゴリー
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ノバルティス アーゲー
ノバルティス アーゲー
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Application filed by ノバルティス アーゲー, ノバルティス アーゲー filed Critical ノバルティス アーゲー
Publication of JP2017528465A publication Critical patent/JP2017528465A/ja
Publication of JP2017528465A5 publication Critical patent/JP2017528465A5/ja
Priority to JP2021087382A priority Critical patent/JP7288927B2/ja
Priority to JP2023087736A priority patent/JP7591092B2/ja
Priority to JP2024199491A priority patent/JP2025024104A/ja
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/3955—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C07K16/244—Interleukins [IL]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/545—Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Mycology (AREA)
  • Biophysics (AREA)
  • Microbiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Rheumatology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Endocrinology (AREA)
  • Transplantation (AREA)
  • Dermatology (AREA)
  • Pain & Pain Management (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Oncology (AREA)
JP2017513409A 2014-09-10 2015-09-08 乾癬性関節炎患者における構造的損傷の進行を阻害するためのｉｌ−１７アンタゴニストの使用 Withdrawn JP2017528465A (ja)

Priority Applications (3)

Application Number Priority Date Filing Date Title
JP2021087382A JP7288927B2 (ja) 2014-09-10 2021-05-25 乾癬性関節炎患者における構造的損傷の進行を阻害するためのｉｌ－１７アンタゴニストの使用
JP2023087736A JP7591092B2 (ja) 2014-09-10 2023-05-29 乾癬性関節炎患者における構造的損傷の進行を阻害するためのｉｌ－１７アンタゴニストの使用
JP2024199491A JP2025024104A (ja) 2014-09-10 2024-11-15 乾癬性関節炎患者における構造的損傷の進行を阻害するためのｉｌ－１７アンタゴニストの使用

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201462048512P 2014-09-10 2014-09-10
US62/048,512 2014-09-10
PCT/IB2015/056871 WO2016038538A1 (en) 2014-09-10 2015-09-08 Use of il-17 antagonists to inhibit the progression of structural damage in psoriatic arthritis patients

Related Child Applications (1)

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JP2021087382A Division JP7288927B2 (ja) 2014-09-10 2021-05-25 乾癬性関節炎患者における構造的損傷の進行を阻害するためのｉｌ－１７アンタゴニストの使用

Publications (2)

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JP2017528465A true JP2017528465A (ja) 2017-09-28
JP2017528465A5 JP2017528465A5 (cg-RX-API-DMAC7.html) 2018-10-04

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JP2017513409A Withdrawn JP2017528465A (ja) 2014-09-10 2015-09-08 乾癬性関節炎患者における構造的損傷の進行を阻害するためのｉｌ−１７アンタゴニストの使用
JP2021087382A Active JP7288927B2 (ja) 2014-09-10 2021-05-25 乾癬性関節炎患者における構造的損傷の進行を阻害するためのｉｌ－１７アンタゴニストの使用
JP2023087736A Active JP7591092B2 (ja) 2014-09-10 2023-05-29 乾癬性関節炎患者における構造的損傷の進行を阻害するためのｉｌ－１７アンタゴニストの使用
JP2024199491A Pending JP2025024104A (ja) 2014-09-10 2024-11-15 乾癬性関節炎患者における構造的損傷の進行を阻害するためのｉｌ－１７アンタゴニストの使用

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JP2021087382A Active JP7288927B2 (ja) 2014-09-10 2021-05-25 乾癬性関節炎患者における構造的損傷の進行を阻害するためのｉｌ－１７アンタゴニストの使用
JP2023087736A Active JP7591092B2 (ja) 2014-09-10 2023-05-29 乾癬性関節炎患者における構造的損傷の進行を阻害するためのｉｌ－１７アンタゴニストの使用
JP2024199491A Pending JP2025024104A (ja) 2014-09-10 2024-11-15 乾癬性関節炎患者における構造的損傷の進行を阻害するためのｉｌ－１７アンタゴニストの使用

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US (2) US11278618B2 (cg-RX-API-DMAC7.html)
EP (2) EP4406969A3 (cg-RX-API-DMAC7.html)
JP (4) JP2017528465A (cg-RX-API-DMAC7.html)
KR (2) KR20230170796A (cg-RX-API-DMAC7.html)
CN (4) CN115944734A (cg-RX-API-DMAC7.html)
AU (2) AU2015313827C1 (cg-RX-API-DMAC7.html)
BR (1) BR112017003332A2 (cg-RX-API-DMAC7.html)
CA (1) CA2960754A1 (cg-RX-API-DMAC7.html)
DK (1) DK3191120T3 (cg-RX-API-DMAC7.html)
ES (1) ES2981697T3 (cg-RX-API-DMAC7.html)
FI (1) FI3191120T3 (cg-RX-API-DMAC7.html)
HR (1) HRP20240921T1 (cg-RX-API-DMAC7.html)
HU (1) HUE067081T2 (cg-RX-API-DMAC7.html)
LT (1) LT3191120T (cg-RX-API-DMAC7.html)
MX (1) MX2017003216A (cg-RX-API-DMAC7.html)
PL (1) PL3191120T3 (cg-RX-API-DMAC7.html)
PT (1) PT3191120T (cg-RX-API-DMAC7.html)
RS (1) RS65851B1 (cg-RX-API-DMAC7.html)
RU (1) RU2697383C2 (cg-RX-API-DMAC7.html)
SI (1) SI3191120T1 (cg-RX-API-DMAC7.html)
SM (1) SMT202400285T1 (cg-RX-API-DMAC7.html)
WO (1) WO2016038538A1 (cg-RX-API-DMAC7.html)

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CA2960754A1 (en) * 2014-09-10 2016-03-17 Novartis Ag Use of il-17 antagonists to inhibit the progression of structural damage in psoriatic arthritis patients
CA3001260A1 (en) 2015-10-27 2017-05-04 Ucb Biopharma Sprl Methods of treatment using anti-il-17a/f antibodies
TW201842933A (zh) * 2017-05-05 2018-12-16 瑞士商諾華公司 使用il-17拮抗劑選擇性治療氣喘的方法
WO2019040230A1 (en) * 2017-08-23 2019-02-28 Eli Lilly And Company TREATMENT OF GENITAL PSORIASIS
CA3080665A1 (en) * 2017-11-02 2019-05-09 Novartis Ag Method of treating tendinopathy using interleukin-17 (il-17) antagonists
EP3980065A4 (en) * 2019-06-04 2023-07-05 Janssen Biotech, Inc. SAFE AND EFFECTIVE METHOD OF TREATMENT OF PSORIAL ARTHRITIS WITH ANTI-IL23 SPECIFIC ANTIBODY
KR102576258B1 (ko) 2019-12-05 2023-09-11 아주대학교산학협력단 펩타이드 또는 이의 혼합물을 유효성분으로 함유하는 조성물 및 이의 의학적 용도
KR102394378B1 (ko) 2020-10-14 2022-05-03 한림대학교 산학협력단 피부 각질세포에서의 아릴탄화수소 수용체 억제자(AhRR) 과발현 방법

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PT1963368E (pt) 2005-12-13 2012-09-14 Lilly Co Eli Anticorpos anti-il-17
WO2007117749A2 (en) 2006-01-31 2007-10-18 Novartis Ag Il-17 antagonistic antibodies fpr treating cancer
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Publication number Publication date
EP4406969A2 (en) 2024-07-31
AU2018201410A1 (en) 2018-03-22
MX2017003216A (es) 2017-05-23
AU2015313827C1 (en) 2018-08-30
LT3191120T (lt) 2024-07-25
KR20170045240A (ko) 2017-04-26
HUE067081T2 (hu) 2024-09-28
ES2981697T3 (es) 2024-10-10
AU2015313827A1 (en) 2017-02-16
JP2021152021A (ja) 2021-09-30
PL3191120T3 (pl) 2024-08-26
JP2023109973A (ja) 2023-08-08
CN113069542A (zh) 2021-07-06
RU2017107501A3 (cg-RX-API-DMAC7.html) 2019-03-12
SMT202400285T1 (it) 2024-09-16
JP7288927B2 (ja) 2023-06-08
US20170281762A1 (en) 2017-10-05
HRP20240921T1 (hr) 2024-10-11
EP4406969A3 (en) 2024-11-27
FI3191120T3 (fi) 2024-07-10
CA2960754A1 (en) 2016-03-17
CN115944734A (zh) 2023-04-11
CN107073110A (zh) 2017-08-18
KR20230170796A (ko) 2023-12-19
US11278618B2 (en) 2022-03-22
RS65851B1 (sr) 2024-09-30
RU2017107501A (ru) 2018-10-10
EP3191120A1 (en) 2017-07-19
AU2015313827B2 (en) 2018-02-15
BR112017003332A2 (pt) 2017-11-28
DK3191120T3 (da) 2024-07-15
JP7591092B2 (ja) 2024-11-27
JP2025024104A (ja) 2025-02-19
CN115957326A (zh) 2023-04-14
WO2016038538A1 (en) 2016-03-17
US20220313818A1 (en) 2022-10-06
EP3191120B1 (en) 2024-04-10
RU2697383C2 (ru) 2019-08-13
PT3191120T (pt) 2024-07-16
SI3191120T1 (sl) 2024-10-30

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