JP2017527299A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2017527299A5 JP2017527299A5 JP2017514828A JP2017514828A JP2017527299A5 JP 2017527299 A5 JP2017527299 A5 JP 2017527299A5 JP 2017514828 A JP2017514828 A JP 2017514828A JP 2017514828 A JP2017514828 A JP 2017514828A JP 2017527299 A5 JP2017527299 A5 JP 2017527299A5
- Authority
- JP
- Japan
- Prior art keywords
- curved
- inlet
- microfluidic system
- microchannel
- outlets
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201462051497P | 2014-09-17 | 2014-09-17 | |
| US62/051,497 | 2014-09-17 | ||
| PCT/US2015/050604 WO2016044537A1 (en) | 2014-09-17 | 2015-09-17 | Microfluidic system and method for perfusion bioreactor cell retention |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2017527299A JP2017527299A (ja) | 2017-09-21 |
| JP2017527299A5 true JP2017527299A5 (https=) | 2018-10-25 |
Family
ID=55533830
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017514828A Pending JP2017527299A (ja) | 2014-09-17 | 2015-09-17 | 灌流バイオリアクター細胞保持のためのマイクロ流体システム及び方法 |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US20170292104A1 (https=) |
| EP (1) | EP3194560A4 (https=) |
| JP (1) | JP2017527299A (https=) |
| CN (1) | CN107250341A (https=) |
| WO (1) | WO2016044537A1 (https=) |
Families Citing this family (33)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2014046621A1 (en) | 2012-09-21 | 2014-03-27 | Massachusetts Institute Of Technology | Micro-fluidic device and uses thereof |
| SG11201606832YA (en) | 2014-02-18 | 2016-09-29 | Massachusetts Inst Technology | Biophysically sorted osteoprogenitors from culture expanded bone marrow derived mesenchymal stromal cells (mscs) |
| US10806845B2 (en) | 2014-09-17 | 2020-10-20 | Massachusetts Institute Of Technology | System and method for inertial focusing microfiltration for intra-operative blood salvage autotransfusion |
| JP6912161B2 (ja) * | 2016-02-25 | 2021-07-28 | 株式会社神戸製鋼所 | 流路装置及び液滴形成方法 |
| SG10202108510UA (en) * | 2016-07-21 | 2021-09-29 | Agency Science Tech & Res | Apparatus for outer wall focusing for high volume fraction particle microfiltration and method for manufacture thereof |
| WO2018067915A1 (en) * | 2016-10-07 | 2018-04-12 | Massachusetts Institute Of Technology | Particle isolation/enrichment using continuous closed-loop micro-fluidics |
| US10697964B2 (en) | 2016-11-15 | 2020-06-30 | Massachusetts Institute Of Technology | Liquid biopsy detection of leukemia using closed-loop microfluidics |
| KR101901672B1 (ko) | 2017-01-25 | 2018-10-25 | 주식회사 디오스템스 | 줄기세포 배양기 및 배양 방법, 줄기세포 연속 배양, 추출 및 분리 시스템 및 방법 |
| TWI728225B (zh) * | 2017-01-25 | 2021-05-21 | 英屬開曼群島商鴻騰精密科技股份有限公司 | 微流體盒及其堆疊測試組件 |
| US11161113B2 (en) * | 2017-03-17 | 2021-11-02 | Istanbul Teknik Universitesi | Microchannel having a spiral geometry structured with asymmetrical curls for continuous separation of cancer cells from blood and enrichment thereof in the circulatory system |
| CN106994369A (zh) * | 2017-05-22 | 2017-08-01 | 东南大学 | 通量可调控的微流控集成器件及其制作方法 |
| JP7124475B2 (ja) * | 2018-01-17 | 2022-08-24 | 株式会社Ihi | 細胞培養システム及び細胞培養方法 |
| CN108517284A (zh) * | 2018-03-19 | 2018-09-11 | 复旦大学 | 一种用于研究藻类生长和生殖的微流控芯片 |
| TWI846694B (zh) * | 2018-05-04 | 2024-07-01 | 美商健臻公司 | 具有過濾系統的灌注式生物反應器 |
| WO2019226618A1 (en) * | 2018-05-22 | 2019-11-28 | Nantkwest, Inc. | Methods and systems for cell bed formation during bioprocessing |
| EP3801902B1 (en) | 2018-05-31 | 2024-09-04 | Donaldson Company, Inc. | Droplet sensors for fuel systems |
| JP7087704B2 (ja) * | 2018-06-13 | 2022-06-21 | 株式会社Ihi | 細胞培養システム及び細胞培養方法 |
| WO2019245070A1 (ko) * | 2018-06-20 | 2019-12-26 | 주식회사 디오스템스 | 줄기세포 증식기 및 증식 방법, 줄기세포 연속 증식, 추출 및 분리 시스템 및 방법 |
| WO2020102533A1 (en) | 2018-11-15 | 2020-05-22 | Massachusetts Institute Of Technology | Multi-dimensional double spiral device and methods of use thereof |
| JP2021013333A (ja) * | 2019-07-12 | 2021-02-12 | 株式会社Ihi | 微生物選別システム及び微生物選別方法 |
| EP4513167A3 (en) * | 2019-11-29 | 2025-04-09 | Donaldson Company, Inc. | Systems and methods for separating particles in fluids |
| CN111774103B (zh) * | 2020-06-01 | 2021-09-07 | 东南大学 | 一种高通量血浆分离的多核螺旋惯性分选微流控器件 |
| SE544733C2 (en) * | 2020-07-20 | 2022-10-25 | Javier Cruz | Microfluidic device and method for manipulation of particles in fluids |
| WO2022081511A1 (en) * | 2020-10-13 | 2022-04-21 | Boehringer Ingelheim International Gmbh | Systems and methods for producing a biologic molecule with hydrocyclone cell retention device |
| KR102474060B1 (ko) * | 2020-10-14 | 2022-12-05 | 한국과학기술연구원 | 미세유체칩 유동에 의한 세포입자의 크기별 분리 장치와 방법 |
| JP2023550302A (ja) * | 2020-11-25 | 2023-12-01 | ドナルドソン カンパニー，インコーポレイティド | 最適なマイクロチャネル長を有する流体力学的分離器 |
| US12478899B2 (en) | 2021-06-02 | 2025-11-25 | Donaldson Company, Inc. | Maintenance of hydrodynamic separators |
| US12252678B2 (en) | 2021-12-01 | 2025-03-18 | Microfluidx Ltd | Systems and methods for bioprocessing |
| CN114260037B (zh) * | 2021-12-27 | 2023-02-03 | 杭州电子科技大学 | 一种3d堆叠式多级惯性微流控分选芯片及其制备方法 |
| WO2023211901A1 (en) | 2022-04-28 | 2023-11-02 | Massachusetts Institute Of Technology | Spiral inertial microfluidic devices and methods to remove contaminants |
| CN114813466B (zh) * | 2022-05-05 | 2025-02-18 | 山东大学 | 一种预测水力旋流器分选细胞活性的方法及系统 |
| CN119947829A (zh) * | 2022-09-21 | 2025-05-06 | 佳能株式会社 | 微流路装置、分离装置和分离方法 |
| CN120586947A (zh) * | 2025-04-28 | 2025-09-05 | 华北理工大学 | 收集汗液的微流控平台 |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8931644B2 (en) * | 2006-11-30 | 2015-01-13 | Palo Alto Research Center Incorporated | Method and apparatus for splitting fluid flow in a membraneless particle separation system |
| US9486812B2 (en) * | 2006-11-30 | 2016-11-08 | Palo Alto Research Center Incorporated | Fluidic structures for membraneless particle separation |
| WO2008130977A2 (en) * | 2007-04-16 | 2008-10-30 | The General Hospital Corporation D/B/A Massachusetts General Hospital | Systems and methods for particle focusing in microchannels |
| US20120028272A1 (en) * | 2009-04-01 | 2012-02-02 | University Of Louisville Research Foundation, Inc. | Device and methods for isolating cells |
| US9458489B2 (en) * | 2010-03-04 | 2016-10-04 | Massachusetts Institute Of Technology | Microfluidics sorter for cell detection and isolation |
| WO2013109520A1 (en) * | 2012-01-18 | 2013-07-25 | Bayer Healthcare Llc | Perfusion bioreactor systems and methods of operating the same |
| US9987632B2 (en) * | 2012-02-03 | 2018-06-05 | University Of Cincinnati | Microfluidic methods for passive separation of cells and particles |
| US9416344B2 (en) * | 2012-03-15 | 2016-08-16 | Flodesign Sonics, Inc. | Bioreactor using acoustic standing waves |
| WO2013144253A1 (en) * | 2012-03-29 | 2013-10-03 | Arizona Board Of Regents On Behalf University Of Arizona | Cell culture apparatus and culture methods using same |
| WO2014046621A1 (en) * | 2012-09-21 | 2014-03-27 | Massachusetts Institute Of Technology | Micro-fluidic device and uses thereof |
| US9804068B2 (en) * | 2012-09-28 | 2017-10-31 | University Of Maryland | Particle separation and concentration using spiral inertial filtration |
| US20140093952A1 (en) * | 2012-10-02 | 2014-04-03 | David Serway | Bioreactor Tangential Flow Perfusion Filter System |
| CN103981093B (zh) * | 2014-04-24 | 2017-01-04 | 上海泰因生物技术有限公司 | 一种用生物反应器进行细胞特性筛选的装置与方法 |
-
2015
- 2015-09-17 US US15/512,003 patent/US20170292104A1/en not_active Abandoned
- 2015-09-17 CN CN201580062211.0A patent/CN107250341A/zh active Pending
- 2015-09-17 WO PCT/US2015/050604 patent/WO2016044537A1/en not_active Ceased
- 2015-09-17 EP EP15841214.8A patent/EP3194560A4/en not_active Withdrawn
- 2015-09-17 JP JP2017514828A patent/JP2017527299A/ja active Pending
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2017527299A5 (https=) | ||
| Warkiani et al. | Large-volume microfluidic cell sorting for biomedical applications | |
| US10583438B2 (en) | Combined sorting and concentrating particles in a microfluidic device | |
| US20160252436A1 (en) | Cell collecting device | |
| CN108495809B (zh) | 使用微流体装置的多段式靶细胞富集 | |
| KR101662808B1 (ko) | 나선형 분지채널을 이용한 미세유체칩 여과 장치 및 방법 | |
| WO2019117800A1 (en) | Microfluidic device and method for cell separation of a blood sample | |
| JP2015529155A5 (https=) | ||
| CN102743974A (zh) | 海水淡化系统及能量交换腔 | |
| WO2012097450A1 (en) | Apparatus and method for particle separation | |
| ES2918374T3 (es) | Dispositivo de filtración de fluidos y ensamblaje | |
| AU2014240770B2 (en) | Peristaltic pump microfluidic separator | |
| CN112195094A (zh) | 一种微流控芯片盒 | |
| JP2020099256A (ja) | 分離方法 | |
| Yin et al. | Highly efficient capture of circulating tumor cells with low background signals by using pyramidal microcavity array | |
| CN106794423B (zh) | 海水淡化系统及能量回收装置 | |
| EP2196253A3 (en) | Membrane container | |
| EP2809417B1 (en) | Wastewater treatment plant | |
| Bayareh et al. | Cancer cell separation using passive mechanisms: A review | |
| CN104388299B (zh) | 一种用于细胞捕获的微流控芯片 | |
| JP5699710B2 (ja) | 液体クロマトグラフィー装置及び充填剤の充填方法 | |
| EP3897982B1 (en) | Microfluidic device | |
| CN102989256B (zh) | 一种多级过滤器 | |
| Wewala et al. | Design, simulation and comparison of ascending and descending curvilinear microchannels for cancer cell separation from blood | |
| CN112385645A (zh) | 一种多级添加细胞低温保护剂的上层芯片和微装置 |