JP2017526700A - 抗ｐｄ１若しくは抗ｐｄｌ１モノクローナル抗体と組み合わせてシチジン類似体の経口製剤を使用する疾患または障害の治療方法 - Google Patents

抗ｐｄ１若しくは抗ｐｄｌ１モノクローナル抗体と組み合わせてシチジン類似体の経口製剤を使用する疾患または障害の治療方法 Download PDF

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JP2017526700A
JP2017526700A JP2017513044A JP2017513044A JP2017526700A JP 2017526700 A JP2017526700 A JP 2017526700A JP 2017513044 A JP2017513044 A JP 2017513044A JP 2017513044 A JP2017513044 A JP 2017513044A JP 2017526700 A JP2017526700 A JP 2017526700A
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certain embodiments
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azacytidine
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disease
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ファンディ アブデラヒム
ファンディ アブデラヒム
レイセル デビッド
レイセル デビッド
バートン デボラ
バートン デボラ
ベジク ダミル
ベジク ダミル
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Celgene Corp
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    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • C07K16/2818—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against CD28 or CD152
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    • C07—ORGANIC CHEMISTRY
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    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding

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JP2017513044A 2014-09-08 2015-09-08 抗ｐｄ１若しくは抗ｐｄｌ１モノクローナル抗体と組み合わせてシチジン類似体の経口製剤を使用する疾患または障害の治療方法 Pending JP2017526700A (ja)

Applications Claiming Priority (3)

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US201462047463P 2014-09-08 2014-09-08
US62/047,463 2014-09-08
PCT/US2015/048812 WO2016040238A1 (en) 2014-09-08 2015-09-08 Methods for treating a disease or disorder using oral formulations of cytidine analogs in combination with an anti-pd1 or anti-pdl1 monoclonal antibody

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JP2017526700A true JP2017526700A (ja) 2017-09-14
JP2017526700A5 JP2017526700A5 (enExample) 2018-03-08

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US (1) US20160067336A1 (enExample)
EP (1) EP3191104A1 (enExample)
JP (1) JP2017526700A (enExample)
KR (1) KR20170045237A (enExample)
CN (1) CN106604745A (enExample)
AU (1) AU2015315435A1 (enExample)
CA (1) CA2960490A1 (enExample)
EA (1) EA201790543A1 (enExample)
IL (1) IL250887A0 (enExample)
MX (1) MX2017002875A (enExample)
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US11287428B2 (en) 2016-03-16 2022-03-29 H. Lee Moffitt Cancer Center And Research Institute, Inc. PD1 and PDL-1 expression during progression from myelodysplastic syndrome to acute myelogenous leukemia
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WO2018007554A1 (en) * 2016-07-06 2018-01-11 Pierre Fabre Medicament Vinflunine and pd1 and/or pdl1 inhibitor as pharmaceutical combination
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EP3589659B1 (en) 2017-02-28 2025-04-09 Mayo Foundation for Medical Education and Research Combinations for use in the treatment of cancer
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JP2022522843A (ja) * 2019-03-04 2022-04-20 ノース カロライナ ステート ユニバーシティ エピジェネティック調節と免疫チェックポイント遮断の組み合わせのための薬物送達

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WO2016040238A1 (en) 2016-03-17
US20160067336A1 (en) 2016-03-10
IL250887A0 (en) 2017-04-30
EA201790543A1 (ru) 2017-07-31
KR20170045237A (ko) 2017-04-26
MX2017002875A (es) 2017-05-30
SG11201701710SA (en) 2017-04-27
AU2015315435A1 (en) 2017-03-23
CN106604745A (zh) 2017-04-26
CA2960490A1 (en) 2016-03-17
EP3191104A1 (en) 2017-07-19

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