JP2017525752A5 - - Google Patents
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- Publication number
- JP2017525752A5 JP2017525752A5 JP2017515008A JP2017515008A JP2017525752A5 JP 2017525752 A5 JP2017525752 A5 JP 2017525752A5 JP 2017515008 A JP2017515008 A JP 2017515008A JP 2017515008 A JP2017515008 A JP 2017515008A JP 2017525752 A5 JP2017525752 A5 JP 2017525752A5
- Authority
- JP
- Japan
- Prior art keywords
- amino acid
- substantially pure
- acid seq
- protein
- homology
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 102000004169 proteins and genes Human genes 0.000 claims 100
- 108090000623 proteins and genes Proteins 0.000 claims 100
- 150000001413 amino acids Chemical class 0.000 claims 65
- 239000000047 product Substances 0.000 claims 26
- 230000000694 effects Effects 0.000 claims 21
- 108060003951 Immunoglobulin Proteins 0.000 claims 15
- 102000018358 immunoglobulin Human genes 0.000 claims 15
- 239000000706 filtrate Substances 0.000 claims 14
- 238000001990 intravenous administration Methods 0.000 claims 6
- 125000003275 alpha amino acid group Chemical group 0.000 claims 5
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims 4
- 239000002031 ethanolic fraction Substances 0.000 claims 4
- 238000001914 filtration Methods 0.000 claims 4
- 239000012467 final product Substances 0.000 claims 3
- 229940036107 hepatitis b immunoglobulin Drugs 0.000 claims 3
- 238000004519 manufacturing process Methods 0.000 claims 3
- 238000007865 diluting Methods 0.000 claims 2
- 238000001728 nano-filtration Methods 0.000 claims 2
- 238000000108 ultra-filtration Methods 0.000 claims 2
- 239000000427 antigen Substances 0.000 claims 1
- 102000036639 antigens Human genes 0.000 claims 1
- 108091007433 antigens Proteins 0.000 claims 1
- 208000002672 hepatitis B Diseases 0.000 claims 1
- 238000002955 isolation Methods 0.000 claims 1
- 239000000203 mixture Substances 0.000 claims 1
- 238000000746 purification Methods 0.000 claims 1
- 230000001954 sterilising effect Effects 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201462003664P | 2014-05-28 | 2014-05-28 | |
| US62/003,664 | 2014-05-28 | ||
| PCT/US2015/032807 WO2015184050A1 (en) | 2014-05-28 | 2015-05-28 | Purified compositions of ivig and kh proteins for modulating lymphocytes and treating hepatitis b virus |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2017525752A JP2017525752A (ja) | 2017-09-07 |
| JP2017525752A5 true JP2017525752A5 (enExample) | 2018-05-17 |
Family
ID=54699755
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017515008A Pending JP2017525752A (ja) | 2014-05-28 | 2015-05-28 | 静注用免疫グロブリンの精製組成物及びリンパ球を調整しｂ型肝炎を治療するためのｋｈタンパク質 |
Country Status (10)
| Country | Link |
|---|---|
| EP (1) | EP3148574B1 (enExample) |
| JP (1) | JP2017525752A (enExample) |
| CN (1) | CN107106664A (enExample) |
| AU (1) | AU2015266997A1 (enExample) |
| BR (1) | BR112016027818A2 (enExample) |
| CA (1) | CA2949994A1 (enExample) |
| ES (1) | ES2878043T3 (enExample) |
| MX (1) | MX2016015574A (enExample) |
| RU (1) | RU2016151761A (enExample) |
| WO (1) | WO2015184050A1 (enExample) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107106664A (zh) | 2014-05-28 | 2017-08-29 | 美国稀有抗体抗原供应公司 | 用于调节淋巴细胞和治疗乙型肝炎病毒的ivig蛋白和kh蛋白的纯化组合物 |
| CN107921079A (zh) * | 2015-04-02 | 2018-04-17 | K·黄 | 由组分iii制造静脉注射免疫球蛋白的方法 |
| US10583179B2 (en) * | 2015-04-02 | 2020-03-10 | Kieu Hoang | Method of manufacturing and purifying prothrombin complex concentrate from Fraction III for intravenous injection and a method of curing and preventing Hemophilia A with inhibitors or Hemophilia B in patients infected with HIV-1 and HIV-2 |
| CN118878610B (zh) * | 2024-03-19 | 2025-09-02 | 北京达尔文细胞生物科技有限公司 | 一种蛋白聚合物及其生产工艺 |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3825429C2 (de) * | 1988-07-27 | 1994-02-10 | Biotest Pharma Gmbh | Verfahren zur Herstellung eines intravenös verabreichbaren polyklonalen Immunglobulin-Präparates mit hohem IgM-Gehalt |
| US20040142325A1 (en) * | 2001-09-14 | 2004-07-22 | Liat Mintz | Methods and systems for annotating biomolecular sequences |
| GB0315248D0 (en) * | 2003-06-30 | 2003-08-06 | Hoffmann La Roche | HCV regulated protein expression |
| TWI489994B (zh) * | 2008-03-17 | 2015-07-01 | Baxter Healthcare Sa | 供免疫球蛋白及玻尿酸酶之皮下投藥之用的組合及方法 |
| CA2639003A1 (en) * | 2008-08-20 | 2010-02-20 | Canadian Blood Services | Inhibition of fc.gamma.r-mediated phagocytosis with reduced immunoglobulin preparations |
| KR20130070576A (ko) * | 2010-04-09 | 2013-06-27 | 노보자임스 바이오파마 디케이 에이/에스 | 알부민 유도체 및 변이체 |
| MX2012013233A (es) * | 2010-05-14 | 2013-05-20 | Univ Colorado Regents | Grupos que apuntan a receptor 2 de complemento (cr2) mejorados. |
| TW201335181A (zh) | 2012-01-31 | 2013-09-01 | Kieu Hoang | ５５種新發現的蛋白質之序列及其應用 |
| CN107106664A (zh) | 2014-05-28 | 2017-08-29 | 美国稀有抗体抗原供应公司 | 用于调节淋巴细胞和治疗乙型肝炎病毒的ivig蛋白和kh蛋白的纯化组合物 |
-
2015
- 2015-05-28 CN CN201580041532.2A patent/CN107106664A/zh active Pending
- 2015-05-28 BR BR112016027818A patent/BR112016027818A2/pt not_active Application Discontinuation
- 2015-05-28 AU AU2015266997A patent/AU2015266997A1/en not_active Abandoned
- 2015-05-28 MX MX2016015574A patent/MX2016015574A/es unknown
- 2015-05-28 RU RU2016151761A patent/RU2016151761A/ru not_active Application Discontinuation
- 2015-05-28 ES ES15799654T patent/ES2878043T3/es active Active
- 2015-05-28 JP JP2017515008A patent/JP2017525752A/ja active Pending
- 2015-05-28 EP EP15799654.7A patent/EP3148574B1/en not_active Revoked
- 2015-05-28 CA CA2949994A patent/CA2949994A1/en active Pending
- 2015-05-28 WO PCT/US2015/032807 patent/WO2015184050A1/en not_active Ceased
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