JP2017524348A5 - - Google Patents

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Publication number
JP2017524348A5
JP2017524348A5 JP2016572566A JP2016572566A JP2017524348A5 JP 2017524348 A5 JP2017524348 A5 JP 2017524348A5 JP 2016572566 A JP2016572566 A JP 2016572566A JP 2016572566 A JP2016572566 A JP 2016572566A JP 2017524348 A5 JP2017524348 A5 JP 2017524348A5
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JP
Japan
Prior art keywords
ptpn2
leukocytes
cell
inhibitor
cells
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2016572566A
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English (en)
Japanese (ja)
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JP2017524348A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/AU2015/050318 external-priority patent/WO2015188228A1/en
Publication of JP2017524348A publication Critical patent/JP2017524348A/ja
Publication of JP2017524348A5 publication Critical patent/JP2017524348A5/ja
Pending legal-status Critical Current

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JP2016572566A 2014-06-10 2015-06-10 養子細胞移入のためのｐｔｐｎ２阻害を用いた白血球の産生方法 Pending JP2017524348A (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
AU2014902203A AU2014902203A0 (en) 2014-06-10 Method of producing cells for adoptive cell transfer
AU2014902203 2014-06-10
AU2015901171 2015-03-31
AU2015901171A AU2015901171A0 (en) 2015-03-31 Method of producing cells for adoptive cell transfer (2)
PCT/AU2015/050318 WO2015188228A1 (en) 2014-06-10 2015-06-10 Method of producing leukocytes using ptpn2 inhibition for adoptive cell transfer

Publications (2)

Publication Number Publication Date
JP2017524348A JP2017524348A (ja) 2017-08-31
JP2017524348A5 true JP2017524348A5 (https=) 2018-06-07

Family

ID=54832624

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2016572566A Pending JP2017524348A (ja) 2014-06-10 2015-06-10 養子細胞移入のためのｐｔｐｎ２阻害を用いた白血球の産生方法

Country Status (5)

Country Link
US (2) US20170224731A1 (https=)
EP (1) EP3154555A4 (https=)
JP (1) JP2017524348A (https=)
AU (1) AU2015274242A1 (https=)
WO (1) WO2015188228A1 (https=)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2592821B (en) 2015-07-31 2022-01-12 Univ Minnesota Modified cells and methods of therapy
JP7181862B2 (ja) 2016-10-18 2022-12-01 リージェンツ オブ ザ ユニバーシティ オブ ミネソタ 腫瘍浸潤リンパ球および治療の方法
US11261428B2 (en) 2018-03-15 2022-03-01 KSQ Therapeutics, Inc. Gene-regulating compositions and methods for improved immunotherapy
WO2018148378A1 (en) * 2017-02-08 2018-08-16 Dana-Farber Cancer Institute, Inc. Modulating biomarkers to increase tumor immunity and improve the efficiacy of cancer immunotherapy
WO2019006418A2 (en) 2017-06-30 2019-01-03 Intima Bioscience, Inc. ADENO-ASSOCIATED VIRAL VECTORS FOR GENE THERAPY
CA3073755A1 (en) 2017-08-24 2019-02-28 The Royal Institution For The Advancement Of Learning/Mcgill Universit Enhancing cd8+ t cells for adoptive cell therapy by inhibiting ptpn1 (ptp1b) and ptpn2 (tc-ptp)
US20190284553A1 (en) 2018-03-15 2019-09-19 KSQ Therapeutics, Inc. Gene-regulating compositions and methods for improved immunotherapy
EP3765608A4 (en) * 2018-03-15 2022-01-12 KSQ Therapeutics, Inc. GENE REGULATORY COMPOSITIONS AND METHODS FOR IMPROVED IMMUNOTHERAPY
AU2019277271A1 (en) * 2018-06-01 2020-12-03 Monash University Methods of activating cells via PTP 1B inhibition
KR20250133466A (ko) 2018-06-21 2025-09-05 칼리코 라이프 사이언시스 엘엘씨 단백질 타이로신 포스파타아제 억제제 및 그의 사용 방법
WO2020072126A2 (en) * 2018-08-07 2020-04-09 Dana-Farber Cancer Institute, Inc. Modulating ptpn2 to increase immune responses and perturbing gene expression in hematopoietic stem cell lineages
MX2021009357A (es) * 2019-02-04 2021-11-17 Ksq Therapeutics Inc Dianas de genes de combinacion para mejorar la inmunoterapia.
PE20252767A1 (es) 2019-03-14 2025-12-22 Calico Life Sciences Llc Inhibidores de la proteina tirosina fosfatasa y metodos para usarlos
US12188045B2 (en) 2019-06-07 2025-01-07 KSQ Therapeutics, Inc. Guide RNA combinations and methods of use
KR20220119038A (ko) * 2019-11-25 2022-08-26 케이에스큐 세러퓨틱스 인코포레이티드 종양 침윤 림프구의 활성화 및 확장을 위한 방법
AU2020395612A1 (en) * 2019-12-04 2022-06-09 Monash University Methods of activating cytotoxic leukocytes using PTP1B and PTPN2 inhibitors
JP2023506227A (ja) * 2019-12-12 2023-02-15 カムクワット バイオサイエンシーズ インコーポレイテッド 免疫活性を強化するための組成物および方法
CN113827727B (zh) * 2020-06-24 2025-04-29 上海交通大学医学院附属瑞金医院 Ptpn2抑制剂在kras突变肿瘤中的应用
AU2022366987A1 (en) 2021-10-14 2024-05-16 Arsenal Biosciences, Inc. Immune cells having co-expressed shrnas and logic gate systems
KR20250158048A (ko) 2023-03-03 2025-11-05 아스널 바이오사이언시스, 인크. Psma 및 ca9을 표적으로 하는 시스템
CN120981456A (zh) 2023-05-24 2025-11-18 金橘生物科技公司 杂环化合物及其用途
WO2025075947A1 (en) * 2023-10-06 2025-04-10 Purdue Research Foundation Selective tc-ptp degraders for cancer immunotherapy

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2008043181A1 (en) * 2006-10-12 2008-04-17 Mcgill University Augmenting stem cell populations by modulating t-cell protein tyrosine phosphatase (tc-ptp)
US9217012B2 (en) * 2009-04-08 2015-12-22 Indiana University Research And Technology Corporation Inhibitors of protein tyrosine phosphatases
WO2014039513A2 (en) * 2012-09-04 2014-03-13 The Trustees Of The University Of Pennsylvania Inhibition of diacylglycerol kinase to augment adoptive t cell transfer
WO2014055442A2 (en) * 2012-10-01 2014-04-10 The Trustees Of The University Of Pennsylvania Compositions and methods for targeting stromal cells for the treatment of cancer
WO2014066137A1 (en) * 2012-10-22 2014-05-01 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Compositions and methods for enhancing cancer immunotherapy
MX2015015638A (es) * 2013-05-13 2016-10-28 Cellectis Metodos para diseñar celulas t altamente activas para inmunoterapia.
ES2897579T3 (es) * 2013-06-10 2022-03-01 Dana Farber Cancer Inst Inc Métodos y composiciones para reducir la inmunosupresión por células tumorales
WO2015127548A1 (en) * 2014-02-28 2015-09-03 The Royal Institution For The Advancement Of Learning / Mcgill University Tc-ptp inhibitors as apc activators for immunotherapy
MX373460B (es) * 2014-03-11 2020-04-07 Cellectis Metodo para generar celulas t compatibles para el trasplante alogenico.

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