JP2017523188A - Ｂｔｋ阻害剤を伴う治療に対するｄｌｂｃｌの応答を予測するためのバイオマーカー - Google Patents

Ｂｔｋ阻害剤を伴う治療に対するｄｌｂｃｌの応答を予測するためのバイオマーカー Download PDF

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JP2017523188A
JP2017523188A JP2017504752A JP2017504752A JP2017523188A JP 2017523188 A JP2017523188 A JP 2017523188A JP 2017504752 A JP2017504752 A JP 2017504752A JP 2017504752 A JP2017504752 A JP 2017504752A JP 2017523188 A JP2017523188 A JP 2017523188A
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dlbcl
ibrutinib
modification
inhibitor
lymphoma
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JP2017523188A5 (https=
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シュヴァイクホファー，カール
エッカート，カール
クオ，ス−ピン
チャン，ベティー
ボープレ，ダリン
チュン，レオ
Original Assignee
ファーマサイクリックス エルエルシー
ファーマサイクリックス エルエルシー
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Publication of JP2017523188A5 publication Critical patent/JP2017523188A5/ja
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
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    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/158—Expression markers
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/46—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans from vertebrates
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    • G01N2333/4703—Regulators; Modulating activity
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    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
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    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2440/00—Post-translational modifications [PTMs] in chemical analysis of biological material
    • G—PHYSICS
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    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/52—Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis

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  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
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  • Pathology (AREA)
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  • Wood Science & Technology (AREA)
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  • Urology & Nephrology (AREA)
  • Public Health (AREA)
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  • Animal Behavior & Ethology (AREA)
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  • General Engineering & Computer Science (AREA)
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  • Food Science & Technology (AREA)
  • General Physics & Mathematics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
JP2017504752A 2014-08-01 2015-07-31 Ｂｔｋ阻害剤を伴う治療に対するｄｌｂｃｌの応答を予測するためのバイオマーカー Pending JP2017523188A (ja)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US201462032430P 2014-08-01 2014-08-01
US62/032,430 2014-08-01
US201562119668P 2015-02-23 2015-02-23
US62/119,668 2015-02-23
US201562127484P 2015-03-03 2015-03-03
US62/127,484 2015-03-03
PCT/US2015/043300 WO2016019341A1 (en) 2014-08-01 2015-07-31 Biomarkers for predicting response of dlbcl to treatment with a btk inhibitor

Publications (2)

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JP2017523188A true JP2017523188A (ja) 2017-08-17
JP2017523188A5 JP2017523188A5 (https=) 2018-09-13

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JP2017504752A Pending JP2017523188A (ja) 2014-08-01 2015-07-31 Ｂｔｋ阻害剤を伴う治療に対するｄｌｂｃｌの応答を予測するためのバイオマーカー

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US (1) US20160032404A1 (https=)
EP (1) EP3185870A4 (https=)
JP (1) JP2017523188A (https=)
KR (1) KR20170042614A (https=)
CN (1) CN106714804A (https=)
AU (1) AU2015296010A1 (https=)
BR (1) BR112017001677A2 (https=)
CA (1) CA2955744A1 (https=)
IL (1) IL250221A0 (https=)
MX (1) MX2017001302A (https=)
RU (1) RU2017106794A (https=)
SG (1) SG11201700774UA (https=)
WO (1) WO2016019341A1 (https=)

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JP2021527097A (ja) * 2018-06-15 2021-10-11 ヤンセン ファーマシューティカ エヌ．ベー． イブルチニブを含む配合物／組成物
JP2022513666A (ja) * 2018-11-30 2022-02-09 ヤンセン バイオテツク，インコーポレーテツド 濾胞性リンパ腫の治療方法
JP2023154581A (ja) * 2022-04-07 2023-10-20 学校法人藤田学園 不明熱患者のｂ細胞リンパ腫診断補助キットおよび情報提供方法
JP7696987B1 (ja) 2023-12-22 2025-06-23 東洋鋼鈑株式会社 遺伝子変異を検出する方法
WO2025134830A1 (ja) * 2023-12-22 2025-06-26 東洋鋼鈑株式会社 遺伝子変異評価用キット
JP7853261B2 (ja) 2018-06-15 2026-04-28 ヤンセン ファーマシューティカ エヌ．ベー． イブルチニブを含む配合物／組成物

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AR077468A1 (es) 2009-07-09 2011-08-31 Array Biopharma Inc Compuestos de pirazolo (1,5 -a) pirimidina sustituidos como inhibidores de trk- quinasa
NZ604708A (en) 2010-05-20 2015-05-29 Array Biopharma Inc Macrocyclic compounds as trk kinase inhibitors
CN107898791A (zh) 2010-06-03 2018-04-13 药品循环有限责任公司 布鲁顿酪氨酸激酶(btk)抑制剂的应用
CN104704129A (zh) 2012-07-24 2015-06-10 药品循环公司 与对布鲁顿酪氨酸激酶(btk)抑制剂的抗性相关的突变
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Cited By (13)

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Publication number Priority date Publication date Assignee Title
JP7853261B2 (ja) 2018-06-15 2026-04-28 ヤンセン ファーマシューティカ エヌ．ベー． イブルチニブを含む配合物／組成物
JP2024023262A (ja) * 2018-06-15 2024-02-21 ヤンセン ファーマシューティカ エヌ．ベー． イブルチニブを含む配合物／組成物
JP7695078B2 (ja) 2018-06-15 2025-06-18 ヤンセン ファーマシューティカ エヌ．ベー． イブルチニブを含む配合物／組成物
JP2021527097A (ja) * 2018-06-15 2021-10-11 ヤンセン ファーマシューティカ エヌ．ベー． イブルチニブを含む配合物／組成物
JP2022513666A (ja) * 2018-11-30 2022-02-09 ヤンセン バイオテツク，インコーポレーテツド 濾胞性リンパ腫の治療方法
JP2023154581A (ja) * 2022-04-07 2023-10-20 学校法人藤田学園 不明熱患者のｂ細胞リンパ腫診断補助キットおよび情報提供方法
JP7423090B2 (ja) 2022-04-07 2024-01-29 学校法人藤田学園 不明熱患者のｂ細胞リンパ腫診断補助キットおよび情報提供方法
JP7696987B1 (ja) 2023-12-22 2025-06-23 東洋鋼鈑株式会社 遺伝子変異を検出する方法
WO2025134830A1 (ja) * 2023-12-22 2025-06-26 東洋鋼鈑株式会社 遺伝子変異評価用キット
JP7698850B1 (ja) 2023-12-22 2025-06-26 東洋鋼鈑株式会社 遺伝子変異評価用キット
JP2025099659A (ja) * 2023-12-22 2025-07-03 東洋鋼鈑株式会社 遺伝子変異評価用キット
JP2025099699A (ja) * 2023-12-22 2025-07-03 東洋鋼鈑株式会社 遺伝子変異を検出する方法
WO2025134829A1 (ja) * 2023-12-22 2025-06-26 東洋鋼鈑株式会社 遺伝子変異を検出する方法

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IL250221A0 (en) 2017-03-30
WO2016019341A1 (en) 2016-02-04
US20160032404A1 (en) 2016-02-04
CN106714804A (zh) 2017-05-24
SG11201700774UA (en) 2017-02-27
KR20170042614A (ko) 2017-04-19
EP3185870A4 (en) 2018-06-20
CA2955744A1 (en) 2016-02-04
RU2017106794A (ru) 2018-09-03
MX2017001302A (es) 2017-10-11
EP3185870A1 (en) 2017-07-05
AU2015296010A1 (en) 2017-02-02
RU2017106794A3 (https=) 2019-02-27
BR112017001677A2 (pt) 2018-07-17

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