JP2017519817A5 - - Google Patents
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- Publication number
- JP2017519817A5 JP2017519817A5 JP2017514984A JP2017514984A JP2017519817A5 JP 2017519817 A5 JP2017519817 A5 JP 2017519817A5 JP 2017514984 A JP2017514984 A JP 2017514984A JP 2017514984 A JP2017514984 A JP 2017514984A JP 2017519817 A5 JP2017519817 A5 JP 2017519817A5
- Authority
- JP
- Japan
- Prior art keywords
- compound according
- methyl
- compound
- phenyl
- unbranched alkyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 150000001875 compounds Chemical class 0.000 claims 19
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 claims 10
- 125000000217 alkyl group Chemical group 0.000 claims 7
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 claims 6
- 125000001495 ethyl group Chemical group [H]C([H])([H])C([H])([H])* 0.000 claims 4
- 125000001449 isopropyl group Chemical group [H]C([H])([H])C([H])(*)C([H])([H])[H] 0.000 claims 4
- 208000035143 Bacterial infection Diseases 0.000 claims 3
- 208000022362 bacterial infectious disease Diseases 0.000 claims 3
- 125000000113 cyclohexyl group Chemical group [H]C1([H])C([H])([H])C([H])([H])C([H])(*)C([H])([H])C1([H])[H] 0.000 claims 3
- 208000015181 infectious disease Diseases 0.000 claims 2
- 239000008194 pharmaceutical composition Substances 0.000 claims 2
- FGRBYDKOBBBPOI-UHFFFAOYSA-N 10,10-dioxo-2-[4-(N-phenylanilino)phenyl]thioxanthen-9-one Chemical compound O=C1c2ccccc2S(=O)(=O)c2ccc(cc12)-c1ccc(cc1)N(c1ccccc1)c1ccccc1 FGRBYDKOBBBPOI-UHFFFAOYSA-N 0.000 claims 1
- 241000894006 Bacteria Species 0.000 claims 1
- 241000192125 Firmicutes Species 0.000 claims 1
- 239000003085 diluting agent Substances 0.000 claims 1
- 238000000034 method Methods 0.000 claims 1
- 229910052760 oxygen Inorganic materials 0.000 claims 1
- 239000000546 pharmaceutical excipient Substances 0.000 claims 1
- 230000002265 prevention Effects 0.000 claims 1
- 125000004076 pyridyl group Chemical group 0.000 claims 1
- 229910052717 sulfur Inorganic materials 0.000 claims 1
- 238000002560 therapeutic procedure Methods 0.000 claims 1
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB1409401.5 | 2014-05-28 | ||
| GBGB1409401.5A GB201409401D0 (en) | 2014-05-28 | 2014-05-28 | Anti-bacterial compounds |
| GB1501969.8 | 2015-02-06 | ||
| GB201501969A GB201501969D0 (en) | 2015-02-06 | 2015-02-06 | Anti-bacterial compounds |
| PCT/GB2015/051550 WO2015181550A1 (en) | 2014-05-28 | 2015-05-28 | Gold (i)-phosphine compounds as anti-bacterial agents |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2017519817A JP2017519817A (ja) | 2017-07-20 |
| JP2017519817A5 true JP2017519817A5 (OSRAM) | 2018-06-21 |
Family
ID=53284305
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017514984A Pending JP2017519817A (ja) | 2014-05-28 | 2015-05-28 | 抗菌薬としての金（ｉ）−ホスフィン化合物 |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US20170204123A1 (OSRAM) |
| EP (1) | EP3148554A1 (OSRAM) |
| JP (1) | JP2017519817A (OSRAM) |
| KR (1) | KR20170012288A (OSRAM) |
| CN (1) | CN106459116A (OSRAM) |
| AU (1) | AU2015265714A1 (OSRAM) |
| CA (1) | CA2950384A1 (OSRAM) |
| EA (1) | EA201692190A1 (OSRAM) |
| IL (1) | IL249176A0 (OSRAM) |
| MX (1) | MX2016015625A (OSRAM) |
| SG (1) | SG11201609377TA (OSRAM) |
| WO (1) | WO2015181550A1 (OSRAM) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB2463181B (en) | 2007-05-14 | 2013-03-27 | Univ New York State Res Found | Induction of a physiological dispersion response in bacterial cells in a biofilm |
| WO2016124936A1 (en) * | 2015-02-06 | 2016-08-11 | Auspherix Limited | Inhibition of microbial persister cells |
| WO2017044044A1 (en) * | 2015-09-08 | 2017-03-16 | Nanyang Technological University | Method of inhibiting quorum sensing in pseudomonas aeruginosa |
| GB201521238D0 (en) * | 2015-12-02 | 2016-01-13 | Auspherix Ltd | Anti-bacterial compounds |
| GB201708844D0 (en) * | 2017-06-02 | 2017-07-19 | Auspherix Ltd | Anti-bacterial compounds |
| EP3837272B1 (en) * | 2018-08-16 | 2025-02-26 | Uniwersytet Jagiellonski | Method for conjugation of biomolecules and use of gold donor for biomolecular complex formation |
| CN109369482B (zh) * | 2018-12-07 | 2020-08-28 | 济源市万洋华康生物科技有限公司 | 一种l-硒代胱氨酸的制备方法 |
| CN113135958B (zh) * | 2021-04-08 | 2022-05-27 | 南京中医药大学 | 氮杂环卡宾硒-金化合物在制备抗耐碳青霉烯类鲍曼不动杆菌药物中的应用 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3883546A (en) * | 1973-08-01 | 1975-05-13 | Smithkline Corp | S-heterocyclic derivatives of phosphine or phosphite gold mercaptides |
| AU1059395A (en) * | 1993-11-24 | 1995-06-13 | Luminis Pty Limited | Triorganophosphinegold (i) thionucleobases with anti-tumor activity |
-
2015
- 2015-05-28 JP JP2017514984A patent/JP2017519817A/ja active Pending
- 2015-05-28 US US15/314,478 patent/US20170204123A1/en not_active Abandoned
- 2015-05-28 CA CA2950384A patent/CA2950384A1/en not_active Abandoned
- 2015-05-28 EA EA201692190A patent/EA201692190A1/ru unknown
- 2015-05-28 EP EP15727051.3A patent/EP3148554A1/en not_active Withdrawn
- 2015-05-28 MX MX2016015625A patent/MX2016015625A/es unknown
- 2015-05-28 CN CN201580027249.4A patent/CN106459116A/zh active Pending
- 2015-05-28 KR KR1020167033901A patent/KR20170012288A/ko not_active Withdrawn
- 2015-05-28 AU AU2015265714A patent/AU2015265714A1/en not_active Abandoned
- 2015-05-28 WO PCT/GB2015/051550 patent/WO2015181550A1/en not_active Ceased
- 2015-05-28 SG SG11201609377TA patent/SG11201609377TA/en unknown
-
2016
- 2016-11-24 IL IL249176A patent/IL249176A0/en unknown
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