JP2017517520A - Ｗｅｅ１阻害剤を用いた癌を処置する方法 - Google Patents

Ｗｅｅ１阻害剤を用いた癌を処置する方法 Download PDF

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JP2017517520A
JP2017517520A JP2016569847A JP2016569847A JP2017517520A JP 2017517520 A JP2017517520 A JP 2017517520A JP 2016569847 A JP2016569847 A JP 2016569847A JP 2016569847 A JP2016569847 A JP 2016569847A JP 2017517520 A JP2017517520 A JP 2017517520A
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cancer
patient
wee1
gene
inhibitors
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JP2017517520A5 (enExample
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マートン，マシュー・ジェイ
ベニータ，ヤイール
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Merck Sharp and Dohme LLC
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    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
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JP2016569847A 2014-05-29 2015-05-26 Ｗｅｅ１阻害剤を用いた癌を処置する方法 Pending JP2017517520A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201462004298P 2014-05-29 2014-05-29
US62/004,298 2014-05-29
PCT/US2015/032351 WO2015183776A1 (en) 2014-05-29 2015-05-26 Methods for treating cancer with a wee1 inhibitor

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Cited By (1)

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JP2023508328A (ja) * 2019-12-20 2023-03-02 リキュリウム アイピー ホールディングス リミテッド ライアビリティー カンパニー 組み合わせ

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Publication number Priority date Publication date Assignee Title
WO2015183776A1 (en) * 2014-05-29 2015-12-03 Merck Sharp & Dohme Corp. Methods for treating cancer with a wee1 inhibitor
WO2019134070A1 (en) * 2018-01-02 2019-07-11 Rui Jin Hospital, Shanghai Jiao Tong University School Of Medicine Panda as novel therapeutic
CA3123871A1 (en) 2018-12-20 2020-06-25 Amgen Inc. Kif18a inhibitors
AU2021257801A1 (en) * 2020-04-14 2022-10-27 Amgen Inc. KIF18A inhibitors for treatment of neoplastic diseases
CN115698006B (zh) * 2020-06-17 2024-03-29 微境生物医药科技(上海)有限公司 作为Wee-1抑制剂的吡唑并[3，4-d]嘧啶-3-酮衍生物
MX2022015794A (es) * 2020-06-24 2023-02-22 Pmv Pharmaceuticals Inc Herramienta complementaria de diagnostico para compuestos reactivantes p53 mutantes.
TW202317092A (zh) 2021-08-26 2023-05-01 美商佛拉斯托醫療公司 Ｋｉｆ１８ａ之吲哚啉抑制劑
TW202508595A (zh) 2023-05-04 2025-03-01 美商銳新醫藥公司 用於ｒａｓ相關疾病或病症之組合療法
WO2025034702A1 (en) 2023-08-07 2025-02-13 Revolution Medicines, Inc. Rmc-6291 for use in the treatment of ras protein-related disease or disorder
WO2025080946A2 (en) 2023-10-12 2025-04-17 Revolution Medicines, Inc. Ras inhibitors
WO2025171296A1 (en) 2024-02-09 2025-08-14 Revolution Medicines, Inc. Ras inhibitors
WO2025217307A1 (en) 2024-04-09 2025-10-16 Revolution Medicines, Inc. Methods for predicting response to a ras(on) inhibitor and combination therapies
WO2025240847A1 (en) 2024-05-17 2025-11-20 Revolution Medicines, Inc. Ras inhibitors

Citations (2)

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WO2013039854A1 (en) * 2011-09-15 2013-03-21 Merck Sharp & Dohme Corp. Compositions and methods for treating cancer
JP2013542997A (ja) * 2010-11-16 2013-11-28 アレイ バイオファーマ、インコーポレイテッド チェックポイントキナーゼ１阻害剤とｗｅｅ１キナーゼ阻害剤の組み合わせ

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MX2009013728A (es) * 2007-06-15 2010-01-25 Banyu Pharma Co Ltd Derivados de bicicloanilina.
EP2473633A4 (en) * 2009-09-02 2013-03-06 Msd Kk USE OF ONE OR MORE BIOMARKERS TO IDENTIFY A WEE1 DISEASED PATIENT AND PROCEDURE FOR TREATING CANCER MEDIATED BY DYSFUNCTIONAL OR ABERRANT P53 BY ADMINISTERING A WEE1 HEMMER
US9506926B2 (en) * 2011-02-18 2016-11-29 The Regents Of The University Of California Molecular predictors of therapeutic response to specific anti-cancer agents
WO2015183776A1 (en) * 2014-05-29 2015-12-03 Merck Sharp & Dohme Corp. Methods for treating cancer with a wee1 inhibitor

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JP2013542997A (ja) * 2010-11-16 2013-11-28 アレイ バイオファーマ、インコーポレイテッド チェックポイントキナーゼ１阻害剤とｗｅｅ１キナーゼ阻害剤の組み合わせ
WO2013039854A1 (en) * 2011-09-15 2013-03-21 Merck Sharp & Dohme Corp. Compositions and methods for treating cancer

Non-Patent Citations (1)

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Title
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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2023508328A (ja) * 2019-12-20 2023-03-02 リキュリウム アイピー ホールディングス リミテッド ライアビリティー カンパニー 組み合わせ
JP7631348B2 (ja) 2019-12-20 2025-02-18 リキュリウム アイピー ホールディングス リミテッド ライアビリティー カンパニー 組み合わせ

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US20170095479A1 (en) 2017-04-06
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US20230083689A1 (en) 2023-03-16
WO2015183776A1 (en) 2015-12-03
US11364243B2 (en) 2022-06-21
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