JP2017517520A - Ｗｅｅ１阻害剤を用いた癌を処置する方法 - Google Patents

Ｗｅｅ１阻害剤を用いた癌を処置する方法 Download PDF

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JP2017517520A
JP2017517520A JP2016569847A JP2016569847A JP2017517520A JP 2017517520 A JP2017517520 A JP 2017517520A JP 2016569847 A JP2016569847 A JP 2016569847A JP 2016569847 A JP2016569847 A JP 2016569847A JP 2017517520 A JP2017517520 A JP 2017517520A
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cancer
patient
wee1
gene
inhibitors
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JP2017517520A5 (enExample
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マートン，マシュー・ジェイ
ベニータ，ヤイール
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Merck Sharp and Dohme LLC
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Merck Sharp and Dohme LLC
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    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
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JP2016569847A 2014-05-29 2015-05-26 Ｗｅｅ１阻害剤を用いた癌を処置する方法 Pending JP2017517520A (ja)

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US201462004298P 2014-05-29 2014-05-29
US62/004,298 2014-05-29
PCT/US2015/032351 WO2015183776A1 (en) 2014-05-29 2015-05-26 Methods for treating cancer with a wee1 inhibitor

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JP2017517520A5 JP2017517520A5 (enExample) 2018-06-28

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JP2023508328A (ja) * 2019-12-20 2023-03-02 リキュリウム アイピー ホールディングス リミテッド ライアビリティー カンパニー 組み合わせ

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JP2017517520A (ja) * 2014-05-29 2017-06-29 メルク・シャープ・アンド・ドーム・コーポレーションＭｅｒｃｋ Ｓｈａｒｐ ＆ Ｄｏｈｍｅ Ｃｏｒｐ． Ｗｅｅ１阻害剤を用いた癌を処置する方法
WO2019134070A1 (en) * 2018-01-02 2019-07-11 Rui Jin Hospital, Shanghai Jiao Tong University School Of Medicine Panda as novel therapeutic
IL283639B2 (en) 2018-12-20 2024-06-01 Amgen Inc Kif18a inhibitors
KR20230011932A (ko) * 2020-04-14 2023-01-25 암젠 인크 신생물 질환의 치료를 위한 kif18a 저해제
WO2021254389A1 (zh) * 2020-06-17 2021-12-23 微境生物医药科技(上海)有限公司 作为Wee-1抑制剂的吡唑并[3，4-d]嘧啶-3-酮衍生物
WO2021262541A1 (en) * 2020-06-24 2021-12-30 Pmv Pharmaceuticals, Inc. Companion diagnostic tool for mutant p53 reactivating compounds
MX2024002391A (es) 2021-08-26 2024-06-03 Volastra Therapeutics Inc Inhibidores de indolina de kif18a.
AU2024265078A1 (en) 2023-05-04 2025-12-11 Revolution Medicines, Inc. Combination therapy for a ras related disease or disorder
US20250049810A1 (en) 2023-08-07 2025-02-13 Revolution Medicines, Inc. Methods of treating a ras protein-related disease or disorder
US20250154171A1 (en) 2023-10-12 2025-05-15 Revolution Medicines, Inc. Ras inhibitors
WO2025171296A1 (en) 2024-02-09 2025-08-14 Revolution Medicines, Inc. Ras inhibitors
WO2025217307A1 (en) 2024-04-09 2025-10-16 Revolution Medicines, Inc. Methods for predicting response to a ras(on) inhibitor and combination therapies
WO2025240847A1 (en) 2024-05-17 2025-11-20 Revolution Medicines, Inc. Ras inhibitors
WO2025255438A1 (en) 2024-06-07 2025-12-11 Revolution Medicines, Inc. Methods of treating a ras protein-related disease or disorder
WO2025265060A1 (en) 2024-06-21 2025-12-26 Revolution Medicines, Inc. Therapeutic compositions and methods for managing treatment-related effects
WO2026006747A1 (en) 2024-06-28 2026-01-02 Revolution Medicines, Inc. Ras inhibitors
WO2026015801A1 (en) 2024-07-12 2026-01-15 Revolution Medicines, Inc. Methods of treating a ras related disease or disorder
WO2026015790A1 (en) 2024-07-12 2026-01-15 Revolution Medicines, Inc. Methods of treating a ras related disease or disorder
WO2026015825A1 (en) 2024-07-12 2026-01-15 Revolution Medicines, Inc. Use of ras inhibitor for treating pancreatic cancer
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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2023508328A (ja) * 2019-12-20 2023-03-02 リキュリウム アイピー ホールディングス リミテッド ライアビリティー カンパニー 組み合わせ
JP7631348B2 (ja) 2019-12-20 2025-02-18 リキュリウム アイピー ホールディングス リミテッド ライアビリティー カンパニー 組み合わせ

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US11364243B2 (en) 2022-06-21
WO2015183776A1 (en) 2015-12-03
US20170095479A1 (en) 2017-04-06
US20200171035A1 (en) 2020-06-04
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