JP2017514867A5 - - Google Patents

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Publication number
JP2017514867A5
JP2017514867A5 JP2016566786A JP2016566786A JP2017514867A5 JP 2017514867 A5 JP2017514867 A5 JP 2017514867A5 JP 2016566786 A JP2016566786 A JP 2016566786A JP 2016566786 A JP2016566786 A JP 2016566786A JP 2017514867 A5 JP2017514867 A5 JP 2017514867A5
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JP
Japan
Prior art keywords
group
alkyl
optionally substituted
heterocyclyl
compound
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Application number
JP2016566786A
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English (en)
Japanese (ja)
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JP2017514867A (ja
JP6479854B2 (ja
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Publication date
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Priority claimed from PCT/EP2015/059453 external-priority patent/WO2015169677A1/en
Publication of JP2017514867A publication Critical patent/JP2017514867A/ja
Publication of JP2017514867A5 publication Critical patent/JP2017514867A5/ja
Application granted granted Critical
Publication of JP6479854B2 publication Critical patent/JP6479854B2/ja
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

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JP2016566786A 2014-05-07 2015-04-30 医薬組成物のためのスルホキシイミン置換キナゾリン Expired - Fee Related JP6479854B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP14167373.1 2014-05-07
EP14167373 2014-05-07
PCT/EP2015/059453 WO2015169677A1 (en) 2014-05-07 2015-04-30 Sulfoximine substituted quinazolines for pharmaceutical compositions

Publications (3)

Publication Number Publication Date
JP2017514867A JP2017514867A (ja) 2017-06-08
JP2017514867A5 true JP2017514867A5 (cg-RX-API-DMAC7.html) 2018-09-20
JP6479854B2 JP6479854B2 (ja) 2019-03-06

Family

ID=50639371

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2016566786A Expired - Fee Related JP6479854B2 (ja) 2014-05-07 2015-04-30 医薬組成物のためのスルホキシイミン置換キナゾリン

Country Status (7)

Country Link
US (1) US10167296B2 (cg-RX-API-DMAC7.html)
EP (1) EP3140300B1 (cg-RX-API-DMAC7.html)
JP (1) JP6479854B2 (cg-RX-API-DMAC7.html)
AU (1) AU2015257917C1 (cg-RX-API-DMAC7.html)
CA (1) CA2944103A1 (cg-RX-API-DMAC7.html)
ES (1) ES2749186T3 (cg-RX-API-DMAC7.html)
WO (1) WO2015169677A1 (cg-RX-API-DMAC7.html)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20170066778A1 (en) * 2015-09-04 2017-03-09 Aunova Medchem LLC Solubility for target compounds
CN109069865A (zh) * 2016-03-31 2018-12-21 南澳大利亚卫生与医学研究所有限公司 抑制高脂肪饮食相关病症的方法

Family Cites Families (27)

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DE19712960A1 (de) 1997-03-27 1998-10-01 Hoechst Ag Benzyloxy-substituierte, anellierte N-Heterocyclen, Verfahren zu ihrer Herstellung und ihre Verwendung als Bradykininrezeptorantagonisten
SE0102147D0 (sv) 2001-06-18 2001-06-18 Pharmacia Ab New methods
DK1439863T3 (da) 2001-10-29 2011-03-14 Boehringer Ingelheim Int MNK-kinase-homologe proteiner, som er involveret i reguleringen af energihomeostase og organelmetabolisme
GB0315587D0 (en) 2003-07-03 2003-08-13 Univ Dundee Anti-inflammatory assay and compounds
CA2558647C (en) 2004-04-08 2013-05-28 Dow Agrosciences Llc Insecticidal n-substituted sulfoximines
EP1746099A1 (en) 2004-12-23 2007-01-24 DeveloGen Aktiengesellschaft Mnk1 or Mnk2 inhibitors
JP5301986B2 (ja) * 2005-06-22 2013-09-25 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング 医薬組成物用のチエノピリミジン類
AU2007222982A1 (en) 2006-03-09 2007-09-13 Pharmacopeia, Inc. 8-Heteroarylpurine Mnk2 inhibitors for treating metabolic disorders
CA2651898A1 (en) * 2006-04-07 2007-10-18 Develogen Aktiengesellschaft Thienopyrimidines having mnk1/mnk2 inhibiting activity for pharmaceutical compositions
EP2044051B1 (en) 2006-06-22 2010-01-27 BIOVITRUM AB (publ) Pyridine and pyrazine derivatives as mnk kinase inhibitors
EP1889847A1 (en) * 2006-07-10 2008-02-20 DeveloGen Aktiengesellschaft Pyrrolopyrimidines for pharmaceutical compositions
JP2010527951A (ja) * 2007-05-24 2010-08-19 バイエル・シエーリング・ファーマ アクチエンゲゼルシャフト キナーゼ阻害剤としての新規なスルホキシイミン置換型キノリン及びキナゾリン誘導体
AU2009286734A1 (en) * 2008-08-26 2010-03-04 Boehringer Ingelheim International Gmbh Thienopyrimidines for pharmaceutical compositions
WO2010117425A1 (en) 2009-03-31 2010-10-14 Biogen Idec Ma Inc. Certain substituted pyrimidines, pharmaceutical compositions thereof, and methods for their use
TW201111378A (en) 2009-09-11 2011-04-01 Bayer Schering Pharma Ag Substituted (heteroarylmethyl) thiohydantoins
UY33241A (es) * 2010-02-26 2011-09-30 Boehringer Ingelheim Int ?Tienopirimidinas que contienen heterocicloalquilo para composiciones farmacéuticas?.
US8853193B2 (en) * 2010-02-26 2014-10-07 Boehringer Ingelheim International Gmbh Thienopyrimidines containing a substituted alkyl group for pharmaceutical compositions
CN102858782A (zh) 2010-02-26 2013-01-02 贝林格尔.英格海姆国际有限公司 用于药物组合物的具有Mnk1/Mnk2 抑制活性的4-[环烷基氧基(杂)芳基氨基]噻吩并[2,3-d]嘧啶
US9170933B2 (en) * 2010-06-28 2015-10-27 International Business Machines Corporation Wear-level of cells/pages/sub-pages/blocks of a memory
AR088082A1 (es) 2011-10-13 2014-05-07 Lilly Co Eli Moduladores selectivos del receptor androgeno
US9540392B2 (en) 2012-05-21 2017-01-10 Bayer Pharma Aktiengesellschaft Thienopyrimidines
TW201412740A (zh) * 2012-09-20 2014-04-01 Bayer Pharma AG 經取代之吡咯并嘧啶胺基苯并噻唑酮
JP2015535833A (ja) * 2012-09-26 2015-12-17 バイエル・ファルマ・アクティエンゲゼルシャフト 過剰増殖疾患の治療において有用な置換インダゾール−ピロロピリミジン
WO2014072244A1 (en) * 2012-11-09 2014-05-15 Boehringer Ingelheim International Gmbh Sulfoximine substituted quinazolines for pharmaceutical compositions
JP2016506944A (ja) * 2013-02-01 2016-03-07 バイエル・ファルマ・アクティエンゲゼルシャフト 置換ピラゾロピリミジニルアミノ−インダゾール
ES2663788T3 (es) * 2013-06-28 2018-04-17 Evotec International Gmbh Quinazolinas sustituidas con sulfoximina y su uso como inhibidores de MNK1 y/o MNK2 quinasas
EP3077383B1 (en) * 2013-12-04 2018-08-22 Evotec International GmbH Sulfoximine substituted quinazolines for pharmaceutical compositions

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