JP2017513859A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2017513859A5 JP2017513859A5 JP2016563034A JP2016563034A JP2017513859A5 JP 2017513859 A5 JP2017513859 A5 JP 2017513859A5 JP 2016563034 A JP2016563034 A JP 2016563034A JP 2016563034 A JP2016563034 A JP 2016563034A JP 2017513859 A5 JP2017513859 A5 JP 2017513859A5
- Authority
- JP
- Japan
- Prior art keywords
- peg
- conjugate
- peg moiety
- integrin
- peptide
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201461979997P | 2014-04-15 | 2014-04-15 | |
| US61/979,997 | 2014-04-15 | ||
| PCT/US2015/025700 WO2015160770A1 (en) | 2014-04-15 | 2015-04-14 | Bi-terminal pegylated integrin-binding peptides and methods of use thereof |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2017513859A JP2017513859A (ja) | 2017-06-01 |
| JP2017513859A5 true JP2017513859A5 (enExample) | 2018-05-31 |
| JP6789823B2 JP6789823B2 (ja) | 2020-11-25 |
Family
ID=54324485
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016563034A Active JP6789823B2 (ja) | 2014-04-15 | 2015-04-14 | 両末端ｐｅｇ化インテグリン結合性ペプチドおよびその使用方法 |
Country Status (8)
| Country | Link |
|---|---|
| US (3) | US10919932B2 (enExample) |
| EP (1) | EP3131566B1 (enExample) |
| JP (1) | JP6789823B2 (enExample) |
| CN (1) | CN106573031B (enExample) |
| AU (2) | AU2015247833B2 (enExample) |
| CA (1) | CA2945945C (enExample) |
| ES (1) | ES2930029T3 (enExample) |
| WO (1) | WO2015160770A1 (enExample) |
Families Citing this family (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2015160770A1 (en) * | 2014-04-15 | 2015-10-22 | The Regents Of The University Of California | Bi-terminal pegylated integrin-binding peptides and methods of use thereof |
| WO2016134164A1 (en) * | 2015-02-18 | 2016-08-25 | Memorial Sloan Kettering Cancer Center | Methods of enhancing cerenkov luminescence using nanoparticles, and compositions related thereto |
| JP7174627B2 (ja) * | 2015-10-23 | 2022-11-17 | ウニフェルシタイト・トゥヴェンテ | インテグリン結合ペプチド及びその使用 |
| CN109563135B (zh) | 2016-06-13 | 2024-01-23 | 加利福尼亚大学董事会 | α(V)β(6)整合素结合肽及其使用方法 |
| US20190321310A1 (en) * | 2016-06-16 | 2019-10-24 | The University Of Liverpool | Chemical composition |
| GB201613166D0 (en) | 2016-07-29 | 2016-09-14 | Vectura Ltd | Polymer |
| US11613607B2 (en) * | 2016-10-07 | 2023-03-28 | Tokyo Institute Of Technology | Branched type hetero monodispersed polyethylene glycol, production method thereof, and conjugate thereof |
| AU2017354041B2 (en) * | 2016-11-01 | 2024-02-01 | Arrowhead Pharmaceuticals, Inc. | Alpha-V beta-6 integrin ligands and uses thereof |
| GB201706472D0 (en) * | 2017-04-24 | 2017-06-07 | Cancer Res Tech Ltd | Tumour-targeting peptide variants |
| SG11202002967SA (en) | 2017-11-01 | 2020-05-28 | Arrowhead Pharmaceuticals Inc | Integrin ligands and uses thereof |
| WO2019154842A1 (en) * | 2018-02-06 | 2019-08-15 | Klinikum Rechts Der Isar Der Technischen Universität München | Compound for intraoperative molecular bioimaging, method of making the same, use thereof in intraoperative molecular bioimaging and surgical method comprising intraoperative molecular bioimaging |
| EP3846858A4 (en) | 2018-09-07 | 2022-10-19 | The Regents of the University of California | ALPHA-(V)BETA(6)INTEGRIN-BINDING PEPTIDES AND METHODS OF USE THEREOF |
| WO2020093055A2 (en) | 2018-11-02 | 2020-05-07 | Indi Molecular, Inc. | Peptide libraries with non-canonical amino acids |
| CN114206906B (zh) * | 2019-07-10 | 2024-02-20 | 香港大学 | Peg化的合成kl4肽、其组合物和方法 |
| CN110522923A (zh) * | 2019-09-19 | 2019-12-03 | 四川大学 | 果糖和rgd肽共修饰的双重靶向三阴性乳腺癌的脂质材料 |
| AU2020356931A1 (en) * | 2019-10-02 | 2022-05-26 | Sirnaomics, Inc. | Oligonucleotides with nucleoside analogs |
| EP4048305A1 (en) * | 2019-10-25 | 2022-08-31 | University of Washington | Computational design of alpha(v) beta (6) integrin binding proteins |
| WO2021226432A2 (en) * | 2020-05-08 | 2021-11-11 | The Regents Of The University Of California | Methods of detecting and treating lung damage in respiratory-related viral infections |
| US20230277490A1 (en) * | 2020-07-31 | 2023-09-07 | Cedars-Sinai Medical Center | Glutamine as an anticancer therapy in solid tumors |
| US20230405129A1 (en) * | 2020-10-20 | 2023-12-21 | The Boad Of Regents Of The University Of Taxas System | Proinflammatory prodrugs |
| WO2022098745A1 (en) * | 2020-11-03 | 2022-05-12 | Indi Molecular, Inc. | Compositions, delivery systems, and methods useful in tumor therapy |
| CN116829541A (zh) * | 2020-12-04 | 2023-09-29 | 加利福尼亚大学董事会 | 肽受体放射性核素治疗 |
| WO2022216920A1 (en) | 2021-04-08 | 2022-10-13 | Arrowhead Pharmaceuticals, Inc. | Rnai agents for inhibiting expression of receptor for advanced glycation end-products, compositions thereof, and methods of use |
| EP4731270A1 (en) | 2023-06-20 | 2026-04-29 | The Regents of The University of California | Combination therapy with peptide receptor radionuclide and dna repair inhibitor |
Family Cites Families (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9108386D0 (en) * | 1991-04-19 | 1991-06-05 | Agricultural Genetics Co | Modified plant viruses as vectors |
| US5429133A (en) | 1992-12-18 | 1995-07-04 | Neoprobe Corporation | Radiation responsive laparoscopic instrument |
| US5446128A (en) | 1993-06-18 | 1995-08-29 | The Board Of Trustees Of The University Of Illinois | Alpha-helix mimetics and methods relating thereto |
| AU3374795A (en) | 1994-08-29 | 1996-03-22 | Prizm Pharmaceuticals, Inc. | Conjugates of vascular endothelial growth factor with targeted agents |
| US5625048A (en) | 1994-11-10 | 1997-04-29 | The Regents Of The University Of California | Modified green fluorescent proteins |
| US6124128A (en) | 1996-08-16 | 2000-09-26 | The Regents Of The University Of California | Long wavelength engineered fluorescent proteins |
| GB0025414D0 (en) | 2000-10-16 | 2000-11-29 | Consejo Superior Investigacion | Nanoparticles |
| WO2002068605A2 (en) | 2001-02-26 | 2002-09-06 | The Regents Of The University Of California | Non-oligomerizing tandem fluorescent proteins |
| WO2002087497A2 (en) * | 2001-04-26 | 2002-11-07 | Board Of Regents, The University Of Texas System | Therapeutic agent/ligand conjugate compositions, their methods of synthesis and use |
| US7469107B2 (en) | 2003-07-23 | 2008-12-23 | Lexmark International, Inc. | Method for providing imaging substance for use in an imaging device via a virtual replenishment |
| EP1756289B1 (en) | 2004-05-24 | 2015-01-14 | Midatech Ltd. | Nanoparticles comprising rna ligands |
| GB0520068D0 (en) * | 2005-10-03 | 2005-11-09 | Cancer Res Technology | av peptide ligand |
| EP1935428A1 (en) * | 2006-12-22 | 2008-06-25 | Antisense Pharma GmbH | Oligonucleotide-polymer conjugates |
| CA2694824A1 (en) * | 2007-08-09 | 2009-02-12 | Syntonix Pharmaceuticals, Inc. | Immunomodulatory peptides |
| KR20130028727A (ko) * | 2010-03-29 | 2013-03-19 | 아브락시스 바이오사이언스, 엘엘씨 | 치료제의 약물 전달 및 유효성 향상 방법 |
| ES2423798T3 (es) * | 2010-11-19 | 2013-09-24 | Universitätsklinikum Freiburg | Hidrogeles de PEG disolubles sensibles a estímulos biofuncionalizados |
| CU23950B1 (es) * | 2011-03-21 | 2013-10-29 | Ct De Ingeniería Genética Y Biotecnología | Péptidos cíclicos con actividad antineoplásica y antiangiogénica |
| US8895055B2 (en) | 2011-12-21 | 2014-11-25 | The Regents Of The University Of California | Telodendrimer nanodiscs without apolipoprotein |
| WO2015160770A1 (en) | 2014-04-15 | 2015-10-22 | The Regents Of The University Of California | Bi-terminal pegylated integrin-binding peptides and methods of use thereof |
| CN109563135B (zh) * | 2016-06-13 | 2024-01-23 | 加利福尼亚大学董事会 | α(V)β(6)整合素结合肽及其使用方法 |
| EP3846858A4 (en) * | 2018-09-07 | 2022-10-19 | The Regents of the University of California | ALPHA-(V)BETA(6)INTEGRIN-BINDING PEPTIDES AND METHODS OF USE THEREOF |
-
2015
- 2015-04-14 WO PCT/US2015/025700 patent/WO2015160770A1/en not_active Ceased
- 2015-04-14 ES ES15779171T patent/ES2930029T3/es active Active
- 2015-04-14 CA CA2945945A patent/CA2945945C/en active Active
- 2015-04-14 EP EP15779171.6A patent/EP3131566B1/en active Active
- 2015-04-14 AU AU2015247833A patent/AU2015247833B2/en active Active
- 2015-04-14 JP JP2016563034A patent/JP6789823B2/ja active Active
- 2015-04-14 CN CN201580032239.XA patent/CN106573031B/zh active Active
-
2016
- 2016-10-13 US US15/292,564 patent/US10919932B2/en active Active
-
2019
- 2019-09-18 AU AU2019232847A patent/AU2019232847B2/en active Active
-
2020
- 2020-12-22 US US17/131,324 patent/US11485758B2/en active Active
-
2022
- 2022-09-15 US US17/945,457 patent/US20240101601A1/en active Pending
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2019524871A5 (enExample) | ||
| JP6789823B2 (ja) | 両末端ｐｅｇ化インテグリン結合性ペプチドおよびその使用方法 | |
| Juliano et al. | Cell‐targeting and cell‐penetrating peptides for delivery of therapeutic and imaging agents | |
| Li et al. | Potent retro-inverso D-peptide for simultaneous targeting of angiogenic blood vasculature and tumor cells | |
| ES2901232T3 (es) | Péptido diana de tumor maligno | |
| ES2744225T3 (es) | Uso de polipéptidos de aprotinina como portadores en conjugados farmacéuticos | |
| Pooja et al. | Bombesin receptors as potential targets for anticancer drug delivery and imaging | |
| Choksi et al. | Functionalized nanoparticles targeting biomarkers for prostate cancer imaging and therapy | |
| Feng et al. | SPECT and near-infrared fluorescence imaging of breast cancer with a neuropilin-1-targeting peptide | |
| JP5721140B2 (ja) | 新生血管に対する標的化剤 | |
| CN104262460A (zh) | 一种靶向人乳腺癌细胞的多肽及其应用 | |
| Ruoslahti | Access granted: iRGD helps silicasome-encased drugs breach the tumor barrier | |
| Rizvi et al. | Engineering peptide drug therapeutics through chemical conjugation and implication in clinics | |
| Ciobanasu | Peptides-based therapy and diagnosis. Strategies for non-invasive therapies in cancer | |
| Guo et al. | Peptides for diagnosis and treatment of ovarian cancer | |
| Su et al. | Enhancing the circulating half-life and the antitumor effects of a tumor-selective cytotoxic peptide by exploiting endogenous serum albumin as a drug carrier | |
| US12485191B2 (en) | Radiopharmaceuticals and methods of use thereof | |
| US20180360755A1 (en) | Target-specific delivery of therapeutic agents | |
| CN113784735A (zh) | 诊断肺癌的方法 | |
| Okarvi et al. | Preparation and evaluation of the tumor-specific antigen-derived synthetic mucin 1 peptide: A potential candidate for the targeting of breast carcinoma | |
| CN108697756A (zh) | Her2肽试剂和方法 | |
| Alshehri et al. | In Vitro Evaluation and Biodistribution Studies of HPMA Copolymers Targeting the Gastrin Releasing Peptide Receptor in Prostate Cancer: Alshehri, Fan, Zhang and Garrison | |
| JPWO2017086090A1 (ja) | 膵癌に特異的な集積性を有するペプチド及びその使用 | |
| Guan et al. | Targeting osteosarcoma vasculature with peptide obtained by phage display | |
| Hendrikx et al. | Use of Cyclic Backbone NGR‐Based SPECT to Increase Efficacy of Postmyocardial Infarction Angiogenesis Imaging |