JP2017509649A5 - - Google Patents

Download PDF

Info

Publication number
JP2017509649A5
JP2017509649A5 JP2016558023A JP2016558023A JP2017509649A5 JP 2017509649 A5 JP2017509649 A5 JP 2017509649A5 JP 2016558023 A JP2016558023 A JP 2016558023A JP 2016558023 A JP2016558023 A JP 2016558023A JP 2017509649 A5 JP2017509649 A5 JP 2017509649A5
Authority
JP
Japan
Prior art keywords
pharmaceutical composition
composition according
seq
dose
body weight
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
JP2016558023A
Other languages
English (en)
Japanese (ja)
Other versions
JP2017509649A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2015/021551 external-priority patent/WO2015143209A1/en
Publication of JP2017509649A publication Critical patent/JP2017509649A/ja
Publication of JP2017509649A5 publication Critical patent/JP2017509649A5/ja
Withdrawn legal-status Critical Current

Links

JP2016558023A 2014-03-19 2015-03-19 Cd40lに対するドメイン抗体を用いる移植拒絶を治療する方法 Withdrawn JP2017509649A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201461955588P 2014-03-19 2014-03-19
US61/955,588 2014-03-19
PCT/US2015/021551 WO2015143209A1 (en) 2014-03-19 2015-03-19 Methods of treating transplant rejection using a domain antibody directed against cd40l

Publications (2)

Publication Number Publication Date
JP2017509649A JP2017509649A (ja) 2017-04-06
JP2017509649A5 true JP2017509649A5 (enExample) 2018-04-05

Family

ID=53055087

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2016558023A Withdrawn JP2017509649A (ja) 2014-03-19 2015-03-19 Cd40lに対するドメイン抗体を用いる移植拒絶を治療する方法

Country Status (13)

Country Link
US (2) US20170051059A1 (enExample)
EP (1) EP3119809A1 (enExample)
JP (1) JP2017509649A (enExample)
KR (1) KR20160124912A (enExample)
CN (1) CN106132429A (enExample)
AU (1) AU2015231180B2 (enExample)
BR (1) BR112016018813A2 (enExample)
CA (1) CA2943177A1 (enExample)
EA (1) EA201691634A1 (enExample)
IL (1) IL247048A0 (enExample)
MX (1) MX2016011102A (enExample)
SG (1) SG11201606521VA (enExample)
WO (1) WO2015143209A1 (enExample)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2700651B1 (en) 2008-07-18 2019-04-10 Bristol-Myers Squibb Company Compositions monovalent for CD28 binding and methods of use
SMT202000091T1 (it) 2011-10-13 2020-05-08 Bristol Myers Squibb Co Polipeptidi anticorpali che antagonizzano cd40l
CN106794255A (zh) 2014-09-30 2017-05-31 百时美施贵宝公司 使用针对cd28的域抗体治疗系统性红斑狼疮的方法
MA41459A (fr) 2015-02-03 2017-12-12 Als Therapy Development Inst Anticorps anti-cd40l et méthodes pour traiter des maladies ou des troubles liés aux cd40l
CN108473561B (zh) * 2015-11-27 2022-12-16 埃博灵克斯股份有限公司 抑制cd40l的多肽
WO2017160975A1 (en) 2016-03-16 2017-09-21 Bristol-Myers Squibb Company Methods of diagnosing and treating lupus
SG10202111207TA (en) 2017-05-24 2021-11-29 Als Therapy Development Inst Therapeutic anti-cd40 ligand antibodies
BR112021026410A2 (pt) * 2019-07-01 2022-02-08 Tonix Pharma Ltd Anticorpos anti-cd154 e usos dos mesmos
EP4688856A1 (en) 2023-04-03 2026-02-11 Regeneron Pharmaceuticals, Inc. Methods of improving transplant survival using il-2 receptor gamma chain antibodies

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7094874B2 (en) 2000-05-26 2006-08-22 Bristol-Myers Squibb Co. Soluble CTLA4 mutant molecules
JP4746552B2 (ja) * 2003-11-04 2011-08-10 ノバルティス バクシンズ アンド ダイアグノスティックス,インコーポレーテッド 自己免疫疾患および炎症性疾患ならびに臓器移植拒絶の処置のためのアンタゴニスト抗cd40抗体の使用
US8277810B2 (en) * 2003-11-04 2012-10-02 Novartis Vaccines & Diagnostics, Inc. Antagonist anti-CD40 antibodies
SI1868635T1 (sl) 2005-04-06 2017-07-31 Bristol-Myers Squibb Company Postopki za zdravljenje imunskih motenj, povezanih s transplantacijo presadkov s topnimi mutiranimi CTLA4 molekulami
CA2634547C (en) 2005-12-20 2016-10-11 Bristol-Myers Squibb Company Stable ctla4 formulation for subcutaneous administration
EP2700651B1 (en) * 2008-07-18 2019-04-10 Bristol-Myers Squibb Company Compositions monovalent for CD28 binding and methods of use
SMT202000091T1 (it) * 2011-10-13 2020-05-08 Bristol Myers Squibb Co Polipeptidi anticorpali che antagonizzano cd40l

Similar Documents

Publication Publication Date Title
US20240174745A1 (en) Antibody Constructs for CLDN18.2 and CD3
JP7682150B2 (ja) プロテアーゼ活性化治療剤を含む組成物および方法
AU2018312251B2 (en) Anti-CD39 antibodies, compositions comprising anti-CD39 antibodies and methods of using anti-CD39 antibodies
JP7665600B2 (ja) 抗腫瘍溶解性ウイルス抗原抗体およびその使用方法
JP2018502060A5 (enExample)
JP2020515637A (ja) 免疫腫瘍剤を伴うps標的化抗体を用いる癌の治療方法
JP6763529B2 (ja) 抗クローディン−2モノクローナル抗体
SI2593128T1 (en) Humanized antibodies targeting the EC1 Kaderina-11 domain and associated compositions and procedures
KR20220159989A (ko) C19 c38 이중특이적 항체
KR20220019806A (ko) 가용성 보체 수용체 1형 변이체 접합체 및 이의 용도
WO2024197157A1 (en) Cd19/cd38 multispecific antibodies
CA3238406A1 (en) Bispecific antibody and use thereof
US20230093169A1 (en) Combinations of antibody constructs and inhibitors of cytokine release syndrome and uses thereof
CN103417965A (zh) 一种含有抗vegf抗体的药物组合物
CA3185332A1 (en) Recombinant rhabdovirus encoding for a cd80 extracellular domain fc-fusion protein
CA3107192C (en) Antibody constructs for cldn18.2 and cd3
WO2025174812A1 (en) Chimeric antigen receptor and/or synnotch receptor systems and cells and methods of their use
ES2860973T3 (es) Diacuerpos monovalentes biespecíficos que pueden unirse a CD123 y CD3 y usos de estos
WO2023036815A1 (en) Targeted regulation of platelet and megakaryocyte activation by heteroreceptor co-clustering
HK40078027B (zh) 针对ror1的抗体及其用途