JP2017507320A5 - - Google Patents
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- JP2017507320A5 JP2017507320A5 JP2016538689A JP2016538689A JP2017507320A5 JP 2017507320 A5 JP2017507320 A5 JP 2017507320A5 JP 2016538689 A JP2016538689 A JP 2016538689A JP 2016538689 A JP2016538689 A JP 2016538689A JP 2017507320 A5 JP2017507320 A5 JP 2017507320A5
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- prostate cancer
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- srsf5
- adamts9
- Prior art date
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- 238000000034 method Methods 0.000 claims 46
- 206010060862 Prostate cancer Diseases 0.000 claims 32
- 208000000236 Prostatic Neoplasms Diseases 0.000 claims 32
- 102000051354 ADAMTS9 Human genes 0.000 claims 20
- 108091005669 ADAMTS9 Proteins 0.000 claims 20
- 101000587438 Homo sapiens Serine/arginine-rich splicing factor 5 Proteins 0.000 claims 20
- 101000734339 Homo sapiens [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 4, mitochondrial Proteins 0.000 claims 20
- 101000988419 Homo sapiens cAMP-specific 3',5'-cyclic phosphodiesterase 4D Proteins 0.000 claims 20
- 102100029703 Serine/arginine-rich splicing factor 5 Human genes 0.000 claims 20
- 102100034825 [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 4, mitochondrial Human genes 0.000 claims 20
- 102100029170 cAMP-specific 3',5'-cyclic phosphodiesterase 4D Human genes 0.000 claims 20
- 239000000523 sample Substances 0.000 claims 20
- 102100034799 CCAAT/enhancer-binding protein delta Human genes 0.000 claims 19
- 102100023344 Centromere protein F Human genes 0.000 claims 19
- -1 ERRI1 Proteins 0.000 claims 19
- 102100022107 Holliday junction recognition protein Human genes 0.000 claims 19
- 101000945965 Homo sapiens CCAAT/enhancer-binding protein delta Proteins 0.000 claims 19
- 101000907941 Homo sapiens Centromere protein F Proteins 0.000 claims 19
- 101001045907 Homo sapiens Holliday junction recognition protein Proteins 0.000 claims 19
- 101001072152 Homo sapiens p53 and DNA damage-regulated protein 1 Proteins 0.000 claims 19
- 102000003620 TRPM3 Human genes 0.000 claims 19
- 108060008547 TRPM3 Proteins 0.000 claims 19
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- 102000051388 ADAMTS1 Human genes 0.000 claims 18
- 108091005660 ADAMTS1 Proteins 0.000 claims 18
- 102100031585 ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 Human genes 0.000 claims 18
- 102100030074 Dickkopf-related protein 1 Human genes 0.000 claims 18
- 101000777636 Homo sapiens ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 Proteins 0.000 claims 18
- 101000864646 Homo sapiens Dickkopf-related protein 1 Proteins 0.000 claims 18
- 101000874532 Homo sapiens Lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase Proteins 0.000 claims 18
- 101000919269 Homo sapiens cAMP-responsive element modulator Proteins 0.000 claims 18
- 102100035655 Lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase Human genes 0.000 claims 18
- 102100029387 cAMP-responsive element modulator Human genes 0.000 claims 18
- 102100033183 Epithelial membrane protein 1 Human genes 0.000 claims 17
- 102000000802 Galectin 3 Human genes 0.000 claims 17
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- 101000966782 Homo sapiens Lysophosphatidic acid receptor 1 Proteins 0.000 claims 17
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- 102100024640 Low-density lipoprotein receptor Human genes 0.000 claims 17
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- 108091007767 MALAT1 Proteins 0.000 claims 17
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- 101001139134 Homo sapiens Krueppel-like factor 4 Proteins 0.000 claims 16
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- 101710148753 Ornithine aminotransferase Proteins 0.000 claims 16
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- 108010037462 Cyclooxygenase 2 Proteins 0.000 claims 15
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- 102100037168 Transcription factor JunB Human genes 0.000 claims 15
- BSFODEXXVBBYOC-UHFFFAOYSA-N 8-[4-(dimethylamino)butan-2-ylamino]quinolin-6-ol Chemical compound C1=CN=C2C(NC(CCN(C)C)C)=CC(O)=CC2=C1 BSFODEXXVBBYOC-UHFFFAOYSA-N 0.000 claims 14
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- 101000853730 Homo sapiens RING finger and transmembrane domain-containing protein 2 Proteins 0.000 claims 13
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- BASFCYQUMIYNBI-UHFFFAOYSA-N platinum Chemical group [Pt] BASFCYQUMIYNBI-UHFFFAOYSA-N 0.000 claims 4
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- LKJPYSCBVHEWIU-KRWDZBQOSA-N (R)-bicalutamide Chemical compound C([C@@](O)(C)C(=O)NC=1C=C(C(C#N)=CC=1)C(F)(F)F)S(=O)(=O)C1=CC=C(F)C=C1 LKJPYSCBVHEWIU-KRWDZBQOSA-N 0.000 claims 2
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- 101100420168 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) RTG2 gene Proteins 0.000 claims 2
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- GZOSMCIZMLWJML-VJLLXTKPSA-N abiraterone Chemical compound C([C@H]1[C@H]2[C@@H]([C@]3(CC[C@H](O)CC3=CC2)C)CC[C@@]11C)C=C1C1=CC=CN=C1 GZOSMCIZMLWJML-VJLLXTKPSA-N 0.000 claims 2
- 229960000853 abiraterone Drugs 0.000 claims 2
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- DKPFODGZWDEEBT-QFIAKTPHSA-N taxane Chemical class C([C@]1(C)CCC[C@@H](C)[C@H]1C1)C[C@H]2[C@H](C)CC[C@@H]1C2(C)C DKPFODGZWDEEBT-QFIAKTPHSA-N 0.000 claims 2
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- 101001092424 Homo sapiens 60S ribosomal protein L37a Proteins 0.000 claims 1
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- 101000653679 Homo sapiens Translationally-controlled tumor protein Proteins 0.000 claims 1
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- ZBZXYUYUUDZCNB-UHFFFAOYSA-N N-cyclohexa-1,3-dien-1-yl-N-phenyl-4-[4-(N-[4-[4-(N-[4-[4-(N-phenylanilino)phenyl]phenyl]anilino)phenyl]phenyl]anilino)phenyl]aniline Chemical group C1=CCCC(N(C=2C=CC=CC=2)C=2C=CC(=CC=2)C=2C=CC(=CC=2)N(C=2C=CC=CC=2)C=2C=CC(=CC=2)C=2C=CC(=CC=2)N(C=2C=CC=CC=2)C=2C=CC(=CC=2)C=2C=CC(=CC=2)N(C=2C=CC=CC=2)C=2C=CC=CC=2)=C1 ZBZXYUYUUDZCNB-UHFFFAOYSA-N 0.000 claims 1
- ZDZOTLJHXYCWBA-VCVYQWHSSA-N N-debenzoyl-N-(tert-butoxycarbonyl)-10-deacetyltaxol Chemical compound O([C@H]1[C@H]2[C@@](C([C@H](O)C3=C(C)[C@@H](OC(=O)[C@H](O)[C@@H](NC(=O)OC(C)(C)C)C=4C=CC=CC=4)C[C@]1(O)C3(C)C)=O)(C)[C@@H](O)C[C@H]1OC[C@]12OC(=O)C)C(=O)C1=CC=CC=C1 ZDZOTLJHXYCWBA-VCVYQWHSSA-N 0.000 claims 1
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB1322034.8A GB201322034D0 (en) | 2013-12-12 | 2013-12-12 | Prostate cancer classification |
| GB1322034.8 | 2013-12-12 | ||
| PCT/GB2014/053694 WO2015087088A2 (en) | 2013-12-12 | 2014-12-12 | Prostate cancer classification |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2017507320A JP2017507320A (ja) | 2017-03-16 |
| JP2017507320A5 true JP2017507320A5 (enExample) | 2018-01-25 |
Family
ID=50030858
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016538689A Pending JP2017507320A (ja) | 2013-12-12 | 2014-12-12 | 前立腺癌分類 |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US10196697B2 (enExample) |
| EP (1) | EP3080293B1 (enExample) |
| JP (1) | JP2017507320A (enExample) |
| KR (1) | KR20160098351A (enExample) |
| CN (1) | CN105940117A (enExample) |
| AU (1) | AU2014363173A1 (enExample) |
| BR (1) | BR112016013182A2 (enExample) |
| CA (1) | CA2932553A1 (enExample) |
| GB (1) | GB201322034D0 (enExample) |
| IL (1) | IL246067A0 (enExample) |
| MX (1) | MX2016007333A (enExample) |
| SG (1) | SG11201604508PA (enExample) |
| WO (1) | WO2015087088A2 (enExample) |
Families Citing this family (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2013302365B2 (en) | 2012-08-16 | 2019-03-21 | Mayo Foundation For Medical Education And Research | Cancer diagnostics using biomarkers |
| WO2017062505A1 (en) * | 2015-10-05 | 2017-04-13 | Cedars-Sinai Medical Center | Method of classifying and diagnosing cancer |
| WO2017112860A1 (en) * | 2015-12-23 | 2017-06-29 | Fred Hutchinson Cancer Research Center | Distinguishing metastatic-lethal prostate cancer from indolent prostate cancer using methylation status of epigenetic markers |
| EP3405583B1 (en) * | 2016-01-20 | 2024-04-03 | Dana-Farber Cancer Institute, Inc. | Compositions and methods for screening and identifying clinically aggressive prostate cancer |
| EP3504348B1 (en) | 2016-08-24 | 2022-12-14 | Decipher Biosciences, Inc. | Use of genomic signatures to predict responsiveness of patients with prostate cancer to post-operative radiation therapy |
| CA3055925A1 (en) * | 2017-03-09 | 2018-09-13 | Decipher Biosciences, Inc. | Subtyping prostate cancer to predict response to hormone therapy |
| WO2019028285A2 (en) | 2017-08-04 | 2019-02-07 | Genomedx, Inc. | USE OF SPECIFIC GENE EXPRESSION OF IMMUNE CELLS FOR THE PROGNOSIS OF PROSTATE CANCER AND THE PREDICTION OF SENSITIVITY TO RADIOTHERAPY |
| US11874276B2 (en) | 2018-04-05 | 2024-01-16 | Dana-Farber Cancer Institute, Inc. | STING levels as a biomarker for cancer immunotherapy |
| CN109295208A (zh) * | 2018-10-26 | 2019-02-01 | 德阳市人民医院 | Pi15作为骨关节炎标志物的应用 |
| SG11202108150RA (en) * | 2019-01-30 | 2021-08-30 | Janssen Pharmaceutica Nv | Methods of treating prostate cancer based on molecular subtypes |
| GB201917428D0 (en) * | 2019-11-29 | 2020-01-15 | Univ Newcastle | Prostate cancer diagnostic |
| CN111518908B (zh) * | 2020-05-18 | 2023-10-17 | 奥尔文泰生物科技(杭州)有限公司 | 尿液前列腺癌标志物组合及其在制备精准诊断试剂中的用途 |
| EP3960878A1 (en) * | 2020-08-31 | 2022-03-02 | Koninklijke Philips N.V. | Selection of a dose for radiotherapy of a prostate cancer subject |
| EP3960877A1 (en) * | 2020-08-31 | 2022-03-02 | Koninklijke Philips N.V. | Prediction of a response of a prostate cancer subject to therapy or personalization of therapy of a prostate cancer subject |
| EP3960876A1 (en) * | 2020-08-31 | 2022-03-02 | Koninklijke Philips N.V. | Prediction of a response of a prostate cancer subject to radiotherapy based on pde4d7 correlated genes |
| JP7477872B2 (ja) * | 2020-09-30 | 2024-05-07 | 国立大学法人大阪大学 | 癌に関連する新規バイオマーカー |
| CN113234820A (zh) * | 2021-04-29 | 2021-08-10 | 北京艾克伦医疗科技有限公司 | 鉴定前列腺癌状态的方法和试剂盒 |
| WO2023135485A1 (en) * | 2022-01-13 | 2023-07-20 | Oslo Universitetssykehus Hf | Prostate cancer markers and uses thereof |
| EP4253567A1 (en) | 2022-03-31 | 2023-10-04 | OncoAssure Limited | A method of predicting risk of an aggressive or recurrent cancer |
| US20250308632A1 (en) * | 2022-05-12 | 2025-10-02 | Veracyte, Inc. | Prognosis and treatment of molecular subtypes of prostate cancer |
| CN116891523B (zh) * | 2023-05-24 | 2024-05-17 | 深圳晶蛋生物医药科技有限公司 | 一种trpm3截短体、包含其的细胞系及其用途 |
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| IE72468B1 (en) | 1987-07-31 | 1997-04-09 | Univ Leland Stanford Junior | Selective amplification of target polynucleotide sequences |
| AU4829690A (en) | 1988-12-16 | 1990-07-10 | Siska Diagnostics, Inc. | Self-sustained, sequence replication system |
| US5437975A (en) | 1991-02-25 | 1995-08-01 | California Institute Of Biological Research | Consensus sequence primed polymerase chain reaction method for fingerprinting genomes |
| US6017704A (en) | 1996-06-03 | 2000-01-25 | The Johns Hopkins University School Of Medicine | Method of detection of methylated nucleic acid using agents which modify unmethylated cytosine and distinguishing modified methylated and non-methylated nucleic acids |
| US7220557B2 (en) | 1997-04-24 | 2007-05-22 | Human Genome Sciences, Inc. | METH1 polynucleotides |
| US8071072B2 (en) * | 1999-10-08 | 2011-12-06 | Hoffmann-La Roche Inc. | Cytotoxicity mediation of cells evidencing surface expression of CD44 |
| AU2002214576A1 (en) | 2000-10-13 | 2002-04-22 | The Government Of The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Genes related to development of refractory prostate cancer |
| EP2316976A1 (en) | 2000-11-28 | 2011-05-04 | Wyeth LLC | Expression analysis of FKBP nucleic acids and polypeptides useful in the diagnosis and treatment of prostate cancer |
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| US7229774B2 (en) | 2001-08-02 | 2007-06-12 | Regents Of The University Of Michigan | Expression profile of prostate cancer |
| US20040029151A1 (en) | 2002-04-09 | 2004-02-12 | Affymetrix, Inc. | Molecular genetic profiling of gleason grades 3 and 4/5 prostate cancer |
| US20050032065A1 (en) | 2002-06-24 | 2005-02-10 | Afar Daniel E. H. | Methods of prognosis of prostate cancer |
| EP1382969A1 (en) | 2002-07-17 | 2004-01-21 | Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. | Diagnosis and prevention of cancer cell invasion |
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| WO2004067726A2 (en) | 2003-01-29 | 2004-08-12 | Keck Graduate Institute | Isothermal reactions for the amplification of oligonucleotides |
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