JP2017507320A - 前立腺癌分類 - Google Patents

前立腺癌分類 Download PDF

Info

Publication number
JP2017507320A
JP2017507320A JP2016538689A JP2016538689A JP2017507320A JP 2017507320 A JP2017507320 A JP 2017507320A JP 2016538689 A JP2016538689 A JP 2016538689A JP 2016538689 A JP2016538689 A JP 2016538689A JP 2017507320 A JP2017507320 A JP 2017507320A
Authority
JP
Japan
Prior art keywords
prostate cancer
subject
expression level
srsf5
pdk4
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2016538689A
Other languages
English (en)
Japanese (ja)
Other versions
JP2017507320A5 (enExample
Inventor
スティーブン・ウォーカー
アンドリーナ・マッキャビガン
ティモシー・デイビソン
リチャード・ケネディ
ポール・ハーキン
ローラ・ヒル
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Almac Diagnostics Ltd
Original Assignee
Almac Diagnostics Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Almac Diagnostics Ltd filed Critical Almac Diagnostics Ltd
Publication of JP2017507320A publication Critical patent/JP2017507320A/ja
Publication of JP2017507320A5 publication Critical patent/JP2017507320A5/ja
Pending legal-status Critical Current

Links

Images

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/337—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having four-membered rings, e.g. taxol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/08—Drugs for disorders of the urinary system of the prostate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/40—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against enzymes
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/575—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57555—Immunoassay; Biospecific binding assay; Materials therefor for cancer of the prostate
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/106—Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/112—Disease subtyping, staging or classification
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/118—Prognosis of disease development
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/158—Expression markers
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/52—Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/60—Complex ways of combining multiple protein biomarkers for diagnosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Analytical Chemistry (AREA)
  • Pathology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Urology & Nephrology (AREA)
  • Biophysics (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Hospice & Palliative Care (AREA)
  • General Engineering & Computer Science (AREA)
  • Oncology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • General Physics & Mathematics (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
JP2016538689A 2013-12-12 2014-12-12 前立腺癌分類 Pending JP2017507320A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB1322034.8 2013-12-12
GBGB1322034.8A GB201322034D0 (en) 2013-12-12 2013-12-12 Prostate cancer classification
PCT/GB2014/053694 WO2015087088A2 (en) 2013-12-12 2014-12-12 Prostate cancer classification

Publications (2)

Publication Number Publication Date
JP2017507320A true JP2017507320A (ja) 2017-03-16
JP2017507320A5 JP2017507320A5 (enExample) 2018-01-25

Family

ID=50030858

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2016538689A Pending JP2017507320A (ja) 2013-12-12 2014-12-12 前立腺癌分類

Country Status (13)

Country Link
US (1) US10196697B2 (enExample)
EP (1) EP3080293B1 (enExample)
JP (1) JP2017507320A (enExample)
KR (1) KR20160098351A (enExample)
CN (1) CN105940117A (enExample)
AU (1) AU2014363173A1 (enExample)
BR (1) BR112016013182A2 (enExample)
CA (1) CA2932553A1 (enExample)
GB (1) GB201322034D0 (enExample)
IL (1) IL246067A0 (enExample)
MX (1) MX2016007333A (enExample)
SG (1) SG11201604508PA (enExample)
WO (1) WO2015087088A2 (enExample)

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2022059105A (ja) * 2020-09-30 2022-04-13 国立大学法人大阪大学 癌に関連する新規バイオマーカー
JP2023538783A (ja) * 2020-08-31 2023-09-11 コーニンクレッカ フィリップス エヌ ヴェ 前立腺がんの放射線治療用線量の選択
JP2023538868A (ja) * 2020-08-31 2023-09-12 コーニンクレッカ フィリップス エヌ ヴェ Ｐｄｅ４ｄ７相関遺伝子に基づく放射線療法に対する前立腺癌被験者の反応の予測
JP2023538944A (ja) * 2020-08-31 2023-09-12 コーニンクレッカ フィリップス エヌ ヴェ 前立腺がん対象者の治療に対する応答の予測又は前立腺がん対象者の治療の個人化

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES3015226T3 (en) 2012-08-16 2025-04-30 Veracyte Sd Inc Prostate cancer prognosis using biomarkers
WO2017062505A1 (en) * 2015-10-05 2017-04-13 Cedars-Sinai Medical Center Method of classifying and diagnosing cancer
CN108474041A (zh) * 2015-12-23 2018-08-31 弗莱德哈钦森癌症研究中心 使用遗传标记的甲基化状态区分转移性-致死性前列腺癌与惰性前列腺癌
US11971411B2 (en) * 2016-01-20 2024-04-30 Dana-Farber Cancer Institute, Inc. Compositions and methods for screening and identifying clinically aggressive prostate cancer
US11414708B2 (en) 2016-08-24 2022-08-16 Decipher Biosciences, Inc. Use of genomic signatures to predict responsiveness of patients with prostate cancer to post-operative radiation therapy
WO2018165600A1 (en) * 2017-03-09 2018-09-13 Genomedx Biosciences, Inc. Subtyping prostate cancer to predict response to hormone therapy
AU2018310987A1 (en) 2017-08-04 2020-02-27 Decipher Biosciences, Inc. Use of immune cell-specific gene expression for prognosis of prostate cancer and prediction of responsiveness to radiation therapy
US11874276B2 (en) 2018-04-05 2024-01-16 Dana-Farber Cancer Institute, Inc. STING levels as a biomarker for cancer immunotherapy
CN109295208A (zh) * 2018-10-26 2019-02-01 德阳市人民医院 Pi15作为骨关节炎标志物的应用
CN113711316A (zh) * 2019-01-30 2021-11-26 詹森药业有限公司 基于分子亚型治疗前列腺癌的方法
GB201917428D0 (en) * 2019-11-29 2020-01-15 Univ Newcastle Prostate cancer diagnostic
CN111518908B (zh) * 2020-05-18 2023-10-17 奥尔文泰生物科技(杭州)有限公司 尿液前列腺癌标志物组合及其在制备精准诊断试剂中的用途
CN113234820A (zh) * 2021-04-29 2021-08-10 北京艾克伦医疗科技有限公司 鉴定前列腺癌状态的方法和试剂盒
US20250109442A1 (en) * 2022-01-13 2025-04-03 Oslo Universitetssykehus Hf Prostate cancer markers and uses thereof
EP4253567A1 (en) 2022-03-31 2023-10-04 OncoAssure Limited A method of predicting risk of an aggressive or recurrent cancer
AU2023269274A1 (en) * 2022-05-12 2024-12-05 Veracyte, Inc. Prognosis and treatment of molecular subtypes of prostate cancer
CN116891523B (zh) * 2023-05-24 2024-05-17 深圳晶蛋生物医药科技有限公司 一种trpm3截短体、包含其的细胞系及其用途

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2007525220A (ja) * 2004-02-27 2007-09-06 オンコセラピー・サイエンス株式会社 Ｐｉｎ−ｐｒｃ移行遺伝子
JP2008271979A (ja) * 2000-11-28 2008-11-13 Wyeth 前立腺癌の診断および治療に有用なｆｋｂｐ核酸およびポリペプチドの発現分析
JP2010529955A (ja) * 2007-05-30 2010-09-02 エフ．ホフマン−ラ ロシュ アーゲー 癌細胞傷害性を介在するキメラ及びヒト化抗−ｃｄ４４抗体
JP2012529021A (ja) * 2009-06-04 2012-11-15 メタノミクス ヘルス ゲーエムベーハー 前立腺癌を診断する手段と方法

Family Cites Families (60)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1340843C (en) 1987-07-31 1999-12-07 J. Lawrence Burg Selective amplification of target polynucleotide sequences
WO1990006995A1 (en) 1988-12-16 1990-06-28 Siska Diagnostics, Inc. Self-sustained sequence replication system
US5437975A (en) 1991-02-25 1995-08-01 California Institute Of Biological Research Consensus sequence primed polymerase chain reaction method for fingerprinting genomes
US6017704A (en) 1996-06-03 2000-01-25 The Johns Hopkins University School Of Medicine Method of detection of methylated nucleic acid using agents which modify unmethylated cytosine and distinguishing modified methylated and non-methylated nucleic acids
US7220557B2 (en) 1997-04-24 2007-05-22 Human Genome Sciences, Inc. METH1 polynucleotides
WO2002031209A2 (en) 2000-10-13 2002-04-18 The Government Of The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Genes related to development of refractory prostate cancer
US20030108963A1 (en) 2001-07-25 2003-06-12 Millennium Pharmaceuticals, Inc. Novel genes, compositions, kit, and methods for identification, assessment, prevention and therapy of prostate cancer
US7229774B2 (en) 2001-08-02 2007-06-12 Regents Of The University Of Michigan Expression profile of prostate cancer
US20040029151A1 (en) 2002-04-09 2004-02-12 Affymetrix, Inc. Molecular genetic profiling of gleason grades 3 and 4/5 prostate cancer
US20050032065A1 (en) 2002-06-24 2005-02-10 Afar Daniel E. H. Methods of prognosis of prostate cancer
EP1382969A1 (en) 2002-07-17 2004-01-21 Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. Diagnosis and prevention of cancer cell invasion
US20050259483A1 (en) 2002-09-30 2005-11-24 Oncotherapy Science, Inc. Genes and polypeptides relating to prostate cancers
WO2004067726A2 (en) 2003-01-29 2004-08-12 Keck Graduate Institute Isothermal reactions for the amplification of oligonucleotides
US20040223970A1 (en) 2003-02-28 2004-11-11 Daniel Afar Antibodies against SLC15A2 and uses thereof
US20070048738A1 (en) 2003-07-14 2007-03-01 Mayo Foundation For Medical Education And Research Methods and compositions for diagnosis, staging and prognosis of prostate cancer
US7666595B2 (en) 2005-02-25 2010-02-23 The Brigham And Women's Hospital, Inc. Biomarkers for predicting prostate cancer progression
EP1874471A4 (en) 2005-03-16 2008-12-10 Sidney Kimmel Cancer Ct METHOD AND COMPOSITIONS FOR PREDICTING DEATH BY CANCER AND SURVIVAL OF PROSTATE CANCER USING GENE EXPRESSION SIGNATURES
KR20080006617A (ko) 2005-04-15 2008-01-16 백톤 디킨슨 앤드 컴퍼니 패혈증의 진단
EP1717320A1 (en) 2005-04-26 2006-11-02 TopoTarget Germany AG Identification of human gene sequences of cancer antigens expressed in metastatic carcinoma and involved in metastasis formation, and their use in cancer diagnosis, prognosis and therapy
CA2622440A1 (en) 2005-09-14 2007-03-22 National Research Council Of Canada Molecular method for diagnosis of prostate cancer
US20070059753A1 (en) 2005-09-15 2007-03-15 Tatiana Vener Detecting gene methylation
EP1951911A2 (en) 2005-11-08 2008-08-06 Euclid Diagnostics LLC Materials and methods for assaying for methylation of cpg islands associated with genes in the evaluation of cancer
WO2008067065A2 (en) 2006-10-19 2008-06-05 Shiv Srivastava Methods, kits, and systems for diagnosing and prognosing prostate cancer using secreted biomarkers
US8338109B2 (en) 2006-11-02 2012-12-25 Mayo Foundation For Medical Education And Research Predicting cancer outcome
WO2008086478A2 (en) 2007-01-10 2008-07-17 Henry Ford Health System Methods and compositions for identification of prostate cancer markers
US20100233691A1 (en) 2007-03-30 2010-09-16 Source Precision Medicine, Inc. D/B/A Source Mdx Gene Expression Profiling for Identification, Monitoring and Treatment of Prostate Cancer
US8709731B2 (en) 2007-08-24 2014-04-29 Oncotherapy Science, Inc. DKK1 oncogene as therapeutic target for cancer and a diagnosing marker
WO2009151503A2 (en) 2008-04-10 2009-12-17 University Of Florida Research Foundation, Inc. Compositions and methods for the treatment of a neoplasia
JP2011516077A (ja) 2008-04-11 2011-05-26 チャイナ シンセティック ラバー コーポレイション 癌を検出するための方法、薬剤、およびキット
CA2725978A1 (en) 2008-05-28 2009-12-03 Genomedx Biosciences, Inc. Systems and methods for expression-based discrimination of distinct clinical disease states in prostate cancer
US20090298082A1 (en) 2008-05-30 2009-12-03 Klee George G Biomarker panels for predicting prostate cancer outcomes
EP2405022A3 (en) 2008-07-08 2012-05-02 Genomic Health, Inc. Gene expression profiling for predicting the survivability of prostate cancer subjects
KR20110052627A (ko) 2008-07-16 2011-05-18 다나-파버 캔서 인스티튜트 인크. 전립선암과 관련된 시그너처 및 ｐｃ결정인자 및 그의 사용 방법
US20100055705A1 (en) 2008-08-29 2010-03-04 Wilson Gerald M Compositions and methods for diagnosing and treating cancer
CN102308004A (zh) 2008-10-30 2012-01-04 卡里斯生命科学卢森堡控股有限责任公司 评价rna图案的方法
WO2010065940A1 (en) 2008-12-04 2010-06-10 The Regents Of The University Of California Materials and methods for determining diagnosis and prognosis of prostate cancer
US20120041274A1 (en) 2010-01-07 2012-02-16 Myriad Genetics, Incorporated Cancer biomarkers
US8753892B2 (en) 2009-05-12 2014-06-17 Koninklijke Philips N.V. Phosphodiesterase 4D7 as prostate cancer marker
KR20120036842A (ko) 2009-05-12 2012-04-18 코닌클리케 필립스 일렉트로닉스 엔.브이. 악성의 호르몬 민감성 전립선 암에 대한 마커로서의 포스포디에스테라제 4ｄ7
US8993604B2 (en) 2009-06-30 2015-03-31 Siga Technologies, Inc. Treatment and prevention of dengue virus infections
EP2309273B1 (en) 2009-09-16 2016-05-18 ZEILLINGER, Robert Novel tumor marker determination
AU2010326066A1 (en) 2009-12-01 2012-06-21 Compendia Bioscience, Inc. Classification of cancers
WO2011094233A1 (en) 2010-01-26 2011-08-04 The Johns Hopkins University Methods of disease classification or prognosis for prostate cancer based on expression of cancer/testis antigens
US20130058925A1 (en) 2010-02-26 2013-03-07 Board Of Regents, The University Of Texas System Epithelial biomarkers for cancer prognosis
JP5838482B2 (ja) 2010-03-11 2016-01-06 オンコセラピー・サイエンス株式会社 Ｈｊｕｒｐペプチドおよびそれを含むワクチン
WO2011153287A2 (en) 2010-06-01 2011-12-08 Indiana University Research And Technology Corporation Materials and methods for diagnosing and predicting the course of prostate cancer
CA2804391A1 (en) 2010-07-07 2012-01-12 Myriad Genetics, Inc. Gene signatures for cancer prognosis
US20130190310A1 (en) 2010-07-26 2013-07-25 The Johns Hopkins University Mig6 and therapeutic efficacy
DK2598659T3 (en) 2010-07-27 2015-05-26 Genomic Health Inc PROCEDURE FOR USING GENEPRESSION FOR DETERMINING PROSTATE CANCER FORECAST
WO2012030840A2 (en) 2010-08-30 2012-03-08 Myriad Genetics, Inc. Gene signatures for cancer diagnosis and prognosis
BR112013027583A2 (pt) 2011-04-28 2016-09-06 Alexander Pearlman assinaturas genômicas de metástases em câncer de próstata
CA2840066A1 (en) 2011-06-27 2013-01-03 Dana-Farber Cancer Institute, Inc. Signatures and determinants associated with prostate cancer progression and methods of use thereof
US20130079241A1 (en) * 2011-09-15 2013-03-28 Jianhua Luo Methods for Diagnosing Prostate Cancer and Predicting Prostate Cancer Relapse
GB201206209D0 (en) 2012-04-06 2012-05-23 Univ Leuven Kath Marker gene based diagnosis, staging and prognosis of prostate caner
JP6280045B2 (ja) 2011-12-22 2018-02-14 アイオーニス ファーマシューティカルズ， インコーポレーテッドＩｏｎｉｓ Ｐｈａｒｍａｃｅｕｔｉｃａｌｓ，Ｉｎｃ． 肺腺癌内転移関連性転写物１（ｍｅｔａｓｔａｓｉｓ−ａｓｓｏｃｉａｔｅｄ−ｉｎ−ｌｕｎｇ−ａｄｅｎｏｃａｒｃｉｎｏｍａ−ｔｒａｎｓｃｒｉｐｔ−１：ｍａｌａｔ−１）の発現調節法
CA2863040C (en) 2012-01-31 2022-04-19 Genomic Health, Inc. Gene expression profile algorithm and test for determining prognosis of prostate cancer
TW201343920A (zh) 2012-03-29 2013-11-01 財團法人國家衛生研究院 預測前列腺癌預後之分子標記、方法與套組
BR102012007246A2 (pt) 2012-03-30 2016-02-10 Fundação Antonio Prudente métodos para prognóstico e classificação de resultados de um evento
US20130288967A1 (en) 2012-04-25 2013-10-31 Euclid Diagnostics Llc Materials and methods for cancer diagnosis by evaluation of the methylation status of cpg islands on chromosomes 6 and 8
CN103146688B (zh) 2012-09-12 2015-05-13 上海长海医院 长链非编码rna作为疾病诊断血液分子标志物的应用

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2008271979A (ja) * 2000-11-28 2008-11-13 Wyeth 前立腺癌の診断および治療に有用なｆｋｂｐ核酸およびポリペプチドの発現分析
JP2007525220A (ja) * 2004-02-27 2007-09-06 オンコセラピー・サイエンス株式会社 Ｐｉｎ−ｐｒｃ移行遺伝子
JP2010529955A (ja) * 2007-05-30 2010-09-02 エフ．ホフマン−ラ ロシュ アーゲー 癌細胞傷害性を介在するキメラ及びヒト化抗−ｃｄ４４抗体
JP2012529021A (ja) * 2009-06-04 2012-11-15 メタノミクス ヘルス ゲーエムベーハー 前立腺癌を診断する手段と方法

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
S.KAMARAJUGADDA、他６名: "Glucose Oxidation Modulates Anoikis and Tumor Metastasis", MOLECULAR AND CELLULAR BIOLOGY, vol. 32, no. 10, JPN6018038451, May 2012 (2012-05-01), pages 1893 - 1907, ISSN: 0004191686 *

Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2023538783A (ja) * 2020-08-31 2023-09-11 コーニンクレッカ フィリップス エヌ ヴェ 前立腺がんの放射線治療用線量の選択
JP2023538868A (ja) * 2020-08-31 2023-09-12 コーニンクレッカ フィリップス エヌ ヴェ Ｐｄｅ４ｄ７相関遺伝子に基づく放射線療法に対する前立腺癌被験者の反応の予測
JP2023538944A (ja) * 2020-08-31 2023-09-12 コーニンクレッカ フィリップス エヌ ヴェ 前立腺がん対象者の治療に対する応答の予測又は前立腺がん対象者の治療の個人化
JP7790427B2 (ja) 2020-08-31 2025-12-23 コーニンクレッカ フィリップス エヌ ヴェ 前立腺がん対象者の治療に対する応答の予測又は前立腺がん対象者の治療の個人化
JP7838574B2 (ja) 2020-08-31 2026-04-01 コーニンクレッカ フィリップス エヌ ヴェ 前立腺がんの放射線治療用線量の選択
JP2022059105A (ja) * 2020-09-30 2022-04-13 国立大学法人大阪大学 癌に関連する新規バイオマーカー
JP7477872B2 (ja) 2020-09-30 2024-05-07 国立大学法人大阪大学 癌に関連する新規バイオマーカー

Also Published As

Publication number Publication date
EP3080293A2 (en) 2016-10-19
US10196697B2 (en) 2019-02-05
IL246067A0 (en) 2016-07-31
EP3080293B1 (en) 2019-03-13
GB201322034D0 (en) 2014-01-29
CA2932553A1 (en) 2015-06-18
CN105940117A (zh) 2016-09-14
SG11201604508PA (en) 2016-07-28
AU2014363173A1 (en) 2016-07-07
WO2015087088A2 (en) 2015-06-18
BR112016013182A2 (pt) 2017-09-26
KR20160098351A (ko) 2016-08-18
US20160312294A1 (en) 2016-10-27
WO2015087088A3 (en) 2015-09-17
MX2016007333A (es) 2016-10-13

Similar Documents

Publication Publication Date Title
EP3080293B1 (en) Prostate cancer classification
Zheng et al. Leptin receptor maintains cancer stem-like properties in triple negative breast cancer cells
Wouters et al. Comprehensive DNA methylation study identifies novel progression-related and prognostic markers for cutaneous melanoma
Payne et al. DNA methylation biomarkers of prostate cancer: Confirmation of candidates and evidence urine is the most sensitive body fluid for non‐invasive detection
Zhang et al. Downregulation of long non-coding RNA HCG11 predicts a poor prognosis in prostate cancer
US8349555B2 (en) Methods and compositions for predicting death from cancer and prostate cancer survival using gene expression signatures
EP3310927B1 (en) Gene signatures predictive of metastatic disease
US12545961B2 (en) Method of predicting risk of recurrence of cancer
Liu et al. Diagnostic role of Wnt pathway gene promoter methylation in non small cell lung cancer
US20160273048A1 (en) Methods for the surveillance, diagnosis and screening of bladder cancer
WO2015073949A1 (en) Method of subtyping high-grade bladder cancer and uses thereof
Yang et al. Systematic screening of protein-coding gene expression identified HMMR as a potential independent indicator of unfavorable survival in patients with papillary muscle-invasive bladder cancer
WO2012125411A1 (en) Methods of predicting prognosis in cancer
Zhang et al. ZNF154 is a promising diagnosis biomarker and predicts biochemical recurrence in prostate cancer
Amato et al. RASSF1 tumor suppressor gene in pancreatic ductal adenocarcinoma: correlation of expression, chromosomal status and epigenetic changes
US20160010157A1 (en) Methods and compositions relating to proliferative disorders of the prostate
Moğul et al. The PD-L1 Promoter Methylation Predicts Gene And Protein Expression Levels in Urothelial Carcinoma
WO2009074364A1 (en) Novel prognostic breast cancer marker
Liu et al. DNA hypermethylation of MAL gene may act as an independent predictor of favorable prognosis in patients with colorectal cancer
Chehade et al. Clinical implications of liquid biopsies in urogenital tumors: a narrative review
Snyder et al. Discovery and Validation of Clinically Relevant Long Non-Coding RNAs in Colorectal Cancer. Cancers 2022, 14, 3866
Wang et al. Effect of upregulation of DD3 on early detection and prognosis in prostate cancer
Dakubo Prostate Cancer Biomarkers in Circulation
Petricca Non-Invasive Detection and Classification of Prostate Cancer Using Plasma Cell-Free DNA Methylomes
Helleman Expression Profiling of Ovarian Cancer: markers and targets for therapy

Legal Events

Date Code Title Description
A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20171211

A621 Written request for application examination

Free format text: JAPANESE INTERMEDIATE CODE: A621

Effective date: 20171211

A977 Report on retrieval

Free format text: JAPANESE INTERMEDIATE CODE: A971007

Effective date: 20180906

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20181002

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20181221

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20190521

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20190809

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20200114

A02 Decision of refusal

Free format text: JAPANESE INTERMEDIATE CODE: A02

Effective date: 20200804