|
US3773919A
(en)
|
1969-10-23 |
1973-11-20 |
Du Pont |
Polylactide-drug mixtures
|
|
US4364935A
(en)
|
1979-12-04 |
1982-12-21 |
Ortho Pharmaceutical Corporation |
Monoclonal antibody to a human prothymocyte antigen and methods of preparing same
|
|
US4816567A
(en)
|
1983-04-08 |
1989-03-28 |
Genentech, Inc. |
Recombinant immunoglobin preparations
|
|
US5225539A
(en)
|
1986-03-27 |
1993-07-06 |
Medical Research Council |
Recombinant altered antibodies and methods of making altered antibodies
|
|
US5567610A
(en)
|
1986-09-04 |
1996-10-22 |
Bioinvent International Ab |
Method of producing human monoclonal antibodies and kit therefor
|
|
WO1988007089A1
(en)
|
1987-03-18 |
1988-09-22 |
Medical Research Council |
Altered antibodies
|
|
WO1989006692A1
(en)
|
1988-01-12 |
1989-07-27 |
Genentech, Inc. |
Method of treating tumor cells by inhibiting growth factor receptor function
|
|
GB8823869D0
(en)
|
1988-10-12 |
1988-11-16 |
Medical Res Council |
Production of antibodies
|
|
US5175384A
(en)
|
1988-12-05 |
1992-12-29 |
Genpharm International |
Transgenic mice depleted in mature t-cells and methods for making transgenic mice
|
|
US5047335A
(en)
|
1988-12-21 |
1991-09-10 |
The Regents Of The University Of Calif. |
Process for controlling intracellular glycosylation of proteins
|
|
US5530101A
(en)
|
1988-12-28 |
1996-06-25 |
Protein Design Labs, Inc. |
Humanized immunoglobulins
|
|
US5229275A
(en)
|
1990-04-26 |
1993-07-20 |
Akzo N.V. |
In-vitro method for producing antigen-specific human monoclonal antibodies
|
|
US5278299A
(en)
|
1991-03-18 |
1994-01-11 |
Scripps Clinic And Research Foundation |
Method and composition for synthesizing sialylated glycosyl compounds
|
|
ES2136092T3
(es)
|
1991-09-23 |
1999-11-16 |
Medical Res Council |
Procedimientos para la produccion de anticuerpos humanizados.
|
|
US5362852A
(en)
|
1991-09-27 |
1994-11-08 |
Pfizer Inc. |
Modified peptide derivatives conjugated at 2-hydroxyethylamine moieties
|
|
WO1993010260A1
(en)
|
1991-11-21 |
1993-05-27 |
The Board Of Trustees Of The Leland Stanford Junior University |
Controlling degradation of glycoprotein oligosaccharides by extracellular glycosisases
|
|
ATE244763T1
(de)
|
1992-02-11 |
2003-07-15 |
Cell Genesys Inc |
Erzielen von homozygotem durch zielgerichtete genetische ereignisse
|
|
US5573905A
(en)
|
1992-03-30 |
1996-11-12 |
The Scripps Research Institute |
Encoded combinatorial chemical libraries
|
|
WO1993022332A2
(en)
|
1992-04-24 |
1993-11-11 |
Board Of Regents, The University Of Texas System |
Recombinant production of immunoglobulin-like domains in prokaryotic cells
|
|
AU701578B2
(en)
|
1992-08-21 |
1999-02-04 |
Vrije Universiteit Brussel |
Immunoglobulins devoid of light chains
|
|
PT616812E
(pt)
|
1993-03-24 |
2000-04-28 |
Berlex Biosciences |
Combinacao de compostos anti-hormonais e moleculas de ligacao no tratamento do cancro
|
|
US5739277A
(en)
|
1995-04-14 |
1998-04-14 |
Genentech Inc. |
Altered polypeptides with increased half-life
|
|
CA2245835A1
(en)
|
1995-06-14 |
1997-01-03 |
The Regents Of The University Of California |
Novel high affinity human antibodies to tumor antigens
|
|
CA2226575C
(en)
|
1995-07-27 |
2011-10-18 |
Genentech, Inc. |
Stabile isotonic lyophilized protein formulation
|
|
US5834597A
(en)
|
1996-05-20 |
1998-11-10 |
Protein Design Labs, Inc. |
Mutated nonactivating IgG2 domains and anti CD3 antibodies incorporating the same
|
|
US6277375B1
(en)
|
1997-03-03 |
2001-08-21 |
Board Of Regents, The University Of Texas System |
Immunoglobulin-like domains with increased half-lives
|
|
AU5241100A
(en)
|
1999-09-28 |
2001-04-30 |
Universitat Zurich |
Factors having prion-binding activity in serum and plasma and agents to detect transmissible spongiform encephalopathitis
|
|
CN101289511A
(zh)
|
2000-04-11 |
2008-10-22 |
杰南技术公司 |
多价抗体及其应用
|
|
EP1174440A1
(en)
*
|
2000-07-19 |
2002-01-23 |
U-BISys B.V. |
A selectively-expressed epitope on the human CD38 molecule detected by a phage display library-derived human scFv antibody fragment
|
|
PT1355919E
(pt)
|
2000-12-12 |
2011-03-02 |
Medimmune Llc |
Moléculas com semivida longa, composições que as contêm e suas utilizações
|
|
WO2004042017A2
(en)
|
2002-10-31 |
2004-05-21 |
Genentech, Inc. |
Methods and compositions for increasing antibody production
|
|
CA2513113A1
(en)
|
2003-01-23 |
2004-08-05 |
Genentech, Inc. |
Methods for producing humanized antibodies and improving yield of antibodies or antigen binding fragments in cell culture
|
|
EP2567976B1
(en)
*
|
2005-03-23 |
2017-07-19 |
Genmab A/S |
Antibodies against CD38 for treatment of multiple myeloma
|
|
WO2007044153A1
(en)
*
|
2005-08-31 |
2007-04-19 |
Affymax, Inc. |
Derivatization and low level detection of drugs in biological fluid and other solution matrices using a proxy marker
|
|
EP2089052A4
(en)
*
|
2006-05-24 |
2011-02-16 |
Peg Biosciences |
POLYETHYLENE GLYCOL-BASED LINK COMPOUNDS AND BIOLOGICALLY ACTIVE CONJUGATES BASED ON SAID COMPOUNDS
|
|
EP1914242A1
(en)
*
|
2006-10-19 |
2008-04-23 |
Sanofi-Aventis |
Novel anti-CD38 antibodies for the treatment of cancer
|
|
CN101520150A
(zh)
|
2008-04-08 |
2009-09-02 |
王跃农 |
一种方便型节能吸顶灯
|
|
US20100017480A1
(en)
|
2008-07-17 |
2010-01-21 |
International Business Machines Corporation |
Recipient side grouping of addresses
|
|
US20120122514A1
(en)
|
2008-10-23 |
2012-05-17 |
Qualcomm Incorporated |
Selecting network service providers for multi-mode mobile devices
|
|
US8367419B2
(en)
|
2009-06-25 |
2013-02-05 |
Rutgers, The State University Of New Jersey |
Compositions and methods for detection of explosives
|
|
CA2809819A1
(en)
|
2009-09-09 |
2011-03-17 |
Centrose, Llc |
Extracellular targeted drug conjugates
|
|
DK2580243T3
(da)
*
|
2010-06-09 |
2020-01-13 |
Genmab As |
Antibodies against human cd38
|
|
SI2621531T1
(sl)
*
|
2010-09-27 |
2017-06-30 |
Morphosys Ag |
Anti-cd38 protitelo in lenalidomid ali bortezomib za zdravljenje multiplega mieloma in nhl
|
|
WO2012050884A2
(en)
|
2010-09-28 |
2012-04-19 |
President And Fellows Of Harvard College |
Cardiac glycosides are potent inhibitors of interferon-beta gene expression
|
|
CN103328038A
(zh)
*
|
2010-12-01 |
2013-09-25 |
史拜诺莫度雷森公司 |
向神经解剖结构直接递送药剂
|
|
JOP20210044A1
(ar)
*
|
2010-12-30 |
2017-06-16 |
Takeda Pharmaceuticals Co |
الأجسام المضادة لـ cd38
|
|
JP2014523884A
(ja)
*
|
2011-06-24 |
2014-09-18 |
セントローズ, エルエルシー |
細胞外標的化薬物複合体
|
|
CN104244718A
(zh)
|
2011-12-05 |
2014-12-24 |
伊格尼卡生物治疗公司 |
抗体-药物缀合物以及相关化合物、组合物和方法
|
|
WO2017023760A1
(en)
*
|
2015-07-31 |
2017-02-09 |
Prudent James R |
Extracellular drug conjugates targeting cd20
|
|
US20170049908A1
(en)
*
|
2015-08-17 |
2017-02-23 |
Centrose, Llc |
Extracellular targeted drug conjugates
|