JP2017505772A5 - - Google Patents
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- Publication number
- JP2017505772A5 JP2017505772A5 JP2016548687A JP2016548687A JP2017505772A5 JP 2017505772 A5 JP2017505772 A5 JP 2017505772A5 JP 2016548687 A JP2016548687 A JP 2016548687A JP 2016548687 A JP2016548687 A JP 2016548687A JP 2017505772 A5 JP2017505772 A5 JP 2017505772A5
- Authority
- JP
- Japan
- Prior art keywords
- analog
- spadin
- propeptide
- mixture
- analogue
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000000203 mixture Substances 0.000 claims 20
- 239000008194 pharmaceutical composition Substances 0.000 claims 6
- 208000020401 Depressive disease Diseases 0.000 claims 1
- 230000000903 blocking effect Effects 0.000 claims 1
- 210000004899 c-terminal region Anatomy 0.000 claims 1
- 239000003814 drug Substances 0.000 claims 1
- 230000000694 effects Effects 0.000 claims 1
- 238000004519 manufacturing process Methods 0.000 claims 1
- 108010083945 potassium channel protein TREK-1 Proteins 0.000 claims 1
- 108090000765 processed proteins & peptides Proteins 0.000 claims 1
Images
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201461931954P | 2014-01-27 | 2014-01-27 | |
| US61/931,954 | 2014-01-27 | ||
| PCT/IB2015/000338 WO2015110915A2 (en) | 2014-01-27 | 2015-01-27 | Retro-inverso analogs of spadin display increased antidepressant effects |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019174139A Division JP2020023508A (ja) | 2014-01-27 | 2019-09-25 | spadinのレトロ−インベルソ類似体は増大された抗うつ作用を示す |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2017505772A JP2017505772A (ja) | 2017-02-23 |
| JP2017505772A5 true JP2017505772A5 (cg-RX-API-DMAC7.html) | 2018-03-08 |
| JP6640725B2 JP6640725B2 (ja) | 2020-02-05 |
Family
ID=53264690
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016548687A Expired - Fee Related JP6640725B2 (ja) | 2014-01-27 | 2015-01-27 | spadinのレトロ−インベルソ類似体は増大された抗うつ作用を示す |
| JP2019174139A Pending JP2020023508A (ja) | 2014-01-27 | 2019-09-25 | spadinのレトロ−インベルソ類似体は増大された抗うつ作用を示す |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019174139A Pending JP2020023508A (ja) | 2014-01-27 | 2019-09-25 | spadinのレトロ−インベルソ類似体は増大された抗うつ作用を示す |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US10251937B2 (cg-RX-API-DMAC7.html) |
| EP (1) | EP3099313B1 (cg-RX-API-DMAC7.html) |
| JP (2) | JP6640725B2 (cg-RX-API-DMAC7.html) |
| CA (1) | CA2938019A1 (cg-RX-API-DMAC7.html) |
| WO (1) | WO2015110915A2 (cg-RX-API-DMAC7.html) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2016355236C1 (en) | 2015-11-16 | 2022-09-22 | Medincell | A method for morselizing and/or targeting pharmaceutically active principles to synovial tissue |
| FR3057266B1 (fr) * | 2016-10-11 | 2021-05-21 | Centre Nat Rech Scient | Peptides derives du propeptide ntsr3 et leur utilisation dans le traitement de la depression |
| FR3057267A1 (fr) * | 2016-10-11 | 2018-04-13 | Centre National De La Recherche Scientifique - Cnrs - | Procede de diagnostic/determination de l'efficacite de traitement de la depression |
| KR102250582B1 (ko) * | 2018-05-11 | 2021-05-12 | 고려대학교 산학협력단 | 별아교세포 특이적 수동전도도 억제약물의 스크리닝 시스템 및 이의 활용 |
| FR3099932B1 (fr) | 2019-08-13 | 2022-11-25 | Univ Limoges | Peptides dérivés de la sortiline |
| US20240294603A1 (en) * | 2023-03-02 | 2024-09-05 | Transdermal Biotechnology, Inc. | Systems and methods for delivery of spadin for treatment of depression or other indications |
| US11980651B1 (en) | 2023-06-21 | 2024-05-14 | Transdermal Biotechnology, Inc. | Systems and methods for treatment of hearing using dihexa |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20050272652A1 (en) * | 1999-03-29 | 2005-12-08 | Gault Victor A | Peptide analogues of GIP for treatment of diabetes, insulin resistance and obesity |
| ES2380055T3 (es) * | 2002-12-20 | 2012-05-08 | H. Lundbeck A/S | Modulación de la actividad de neurotrofinas; método de escrutinio |
| EP2077278A1 (fr) * | 2007-12-21 | 2009-07-08 | Centre National de la Recherche Scientifique (CNRS) | Peptide dérivé du récepteur 3 de la neurotensine et utilisation dans le traitemement de maladies psychiatriques |
| JP5715045B2 (ja) * | 2008-04-27 | 2015-05-07 | ハー・ルンドベック・アクチエゼルスカベット | ソルチリンに対する特異的リガンドの設計 |
| SI2658525T1 (en) | 2010-12-29 | 2018-04-30 | Medincell | Biodegradable Composites for Delivery |
| US20120322060A1 (en) * | 2011-04-13 | 2012-12-20 | Centre National De Le Recherche Scientifique - Cnrs - | Diagnosis and monitoring treatment of psychiatric diseases with spadin and related methods |
| JP6134788B2 (ja) * | 2012-06-27 | 2017-05-24 | メドインセルル | 疎水性組成物のための生分解性薬物送達 |
-
2015
- 2015-01-27 WO PCT/IB2015/000338 patent/WO2015110915A2/en not_active Ceased
- 2015-01-27 CA CA2938019A patent/CA2938019A1/en not_active Abandoned
- 2015-01-27 JP JP2016548687A patent/JP6640725B2/ja not_active Expired - Fee Related
- 2015-01-27 US US15/114,241 patent/US10251937B2/en not_active Expired - Fee Related
- 2015-01-27 EP EP15724359.3A patent/EP3099313B1/en active Active
-
2019
- 2019-09-25 JP JP2019174139A patent/JP2020023508A/ja active Pending
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