FR3099932B1 - Peptides dérivés de la sortiline - Google Patents

Peptides dérivés de la sortiline Download PDF

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Publication number
FR3099932B1
FR3099932B1 FR1909182A FR1909182A FR3099932B1 FR 3099932 B1 FR3099932 B1 FR 3099932B1 FR 1909182 A FR1909182 A FR 1909182A FR 1909182 A FR1909182 A FR 1909182A FR 3099932 B1 FR3099932 B1 FR 3099932B1
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FR
France
Prior art keywords
asp
val
leu
gly
ser
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
FR1909182A
Other languages
English (en)
Other versions
FR3099932A1 (fr
Inventor
Camille Granet
Eric Lapeyronnie
Thomas Naves
Paul-François Gallet
Marie-Odile Jauberteau
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Universite de Limoges
Original Assignee
Universite de Limoges
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Universite de Limoges filed Critical Universite de Limoges
Priority to FR1909182A priority Critical patent/FR3099932B1/fr
Priority to PCT/EP2020/072431 priority patent/WO2021028404A1/fr
Priority to US17/634,425 priority patent/US20230212251A1/en
Priority to EP20756814.8A priority patent/EP4013779A1/fr
Priority to CN202080057222.0A priority patent/CN115103855A/zh
Publication of FR3099932A1 publication Critical patent/FR3099932A1/fr
Application granted granted Critical
Publication of FR3099932B1 publication Critical patent/FR3099932B1/fr
Active legal-status Critical Current
Anticipated expiration legal-status Critical

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/10—Fusion polypeptide containing a localisation/targetting motif containing a tag for extracellular membrane crossing, e.g. TAT or VP22
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/40—Fusion polypeptide containing a tag for immunodetection, or an epitope for immunisation

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Immunology (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Cell Biology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)

Abstract

Polypeptide isolé dérivé de la sortiline humaine comprenant ou consistant en une séquence en acides aminés présentant au moins 80% d’identité avec la séquence SEQ ID NO 2Val Leu Ile Val Lys Lys Tyr Val Cys Gly Gly Arg Phe Leu Val His Arg Tyr Ser Val Leu Gln Gln His Ala Glu Ala Asn Gly Val Asp Gly Val Asp Ala Leu Asp Thr Ala Ser His Thr Asn Lys Ser Gly Tyr His Asp Asp Ser Asp Glu Asp Leu Leu Gluà la condition que ledit polypeptide ne contienne pas la séquence SEQ ID NO 3 ou une séquence présentant au moins 80 % d’identité avec la dite séquence SEQ ID NO 3, pour son utilisation en tant que médicament.
FR1909182A 2019-08-13 2019-08-13 Peptides dérivés de la sortiline Active FR3099932B1 (fr)

Priority Applications (5)

Application Number Priority Date Filing Date Title
FR1909182A FR3099932B1 (fr) 2019-08-13 2019-08-13 Peptides dérivés de la sortiline
PCT/EP2020/072431 WO2021028404A1 (fr) 2019-08-13 2020-08-10 Peptides derives de la sortiline
US17/634,425 US20230212251A1 (en) 2019-08-13 2020-08-10 Peptides derived from sortilin
EP20756814.8A EP4013779A1 (fr) 2019-08-13 2020-08-10 Peptides derives de la sortiline
CN202080057222.0A CN115103855A (zh) 2019-08-13 2020-08-10 衍生自分拣蛋白的肽

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR1909182A FR3099932B1 (fr) 2019-08-13 2019-08-13 Peptides dérivés de la sortiline
FR1909182 2019-08-13

Publications (2)

Publication Number Publication Date
FR3099932A1 FR3099932A1 (fr) 2021-02-19
FR3099932B1 true FR3099932B1 (fr) 2022-11-25

Family

ID=69172879

Family Applications (1)

Application Number Title Priority Date Filing Date
FR1909182A Active FR3099932B1 (fr) 2019-08-13 2019-08-13 Peptides dérivés de la sortiline

Country Status (5)

Country Link
US (1) US20230212251A1 (fr)
EP (1) EP4013779A1 (fr)
CN (1) CN115103855A (fr)
FR (1) FR3099932B1 (fr)
WO (1) WO2021028404A1 (fr)

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20120322060A1 (en) 2011-04-13 2012-12-20 Centre National De Le Recherche Scientifique - Cnrs - Diagnosis and monitoring treatment of psychiatric diseases with spadin and related methods
CA2938019A1 (fr) 2014-01-27 2015-07-30 Medincell Analogues retro-inverso de spadine a effets antidepresseurs accrus

Also Published As

Publication number Publication date
WO2021028404A1 (fr) 2021-02-18
EP4013779A1 (fr) 2022-06-22
CN115103855A (zh) 2022-09-23
FR3099932A1 (fr) 2021-02-19
US20230212251A1 (en) 2023-07-06

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