JP2017503842A5 - - Google Patents
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- JP2017503842A5 JP2017503842A5 JP2016548172A JP2016548172A JP2017503842A5 JP 2017503842 A5 JP2017503842 A5 JP 2017503842A5 JP 2016548172 A JP2016548172 A JP 2016548172A JP 2016548172 A JP2016548172 A JP 2016548172A JP 2017503842 A5 JP2017503842 A5 JP 2017503842A5
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- JP
- Japan
- Prior art keywords
- pharmaceutical composition
- composition according
- cell lymphoma
- therapeutic agent
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- Prior art date
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Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201461931078P | 2014-01-24 | 2014-01-24 | |
| US201461931075P | 2014-01-24 | 2014-01-24 | |
| US61/931,078 | 2014-01-24 | ||
| US61/931,075 | 2014-01-24 | ||
| US201462077127P | 2014-11-07 | 2014-11-07 | |
| US62/077,127 | 2014-11-07 | ||
| PCT/US2015/012733 WO2015112888A1 (en) | 2014-01-24 | 2015-01-23 | Apilimod compositions and methods for using same |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020201440A Division JP2021046430A (ja) | 2014-01-24 | 2020-12-04 | 癌治療のためのアピリモド（ａｐｉｌｉｍｏｄ）組成物 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2017503842A JP2017503842A (ja) | 2017-02-02 |
| JP2017503842A5 true JP2017503842A5 (OSRAM) | 2018-03-08 |
| JP6855243B2 JP6855243B2 (ja) | 2021-04-07 |
Family
ID=53681989
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016548172A Expired - Fee Related JP6855243B2 (ja) | 2014-01-24 | 2015-01-23 | 癌治療のためのアピリモド（ａｐｉｌｉｍｏｄ）組成物 |
| JP2020201440A Pending JP2021046430A (ja) | 2014-01-24 | 2020-12-04 | 癌治療のためのアピリモド（ａｐｉｌｉｍｏｄ）組成物 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020201440A Pending JP2021046430A (ja) | 2014-01-24 | 2020-12-04 | 癌治療のためのアピリモド（ａｐｉｌｉｍｏｄ）組成物 |
Country Status (12)
| Country | Link |
|---|---|
| US (3) | US10179135B2 (OSRAM) |
| EP (1) | EP3096757B1 (OSRAM) |
| JP (2) | JP6855243B2 (OSRAM) |
| KR (1) | KR102320190B1 (OSRAM) |
| CN (1) | CN106659716B (OSRAM) |
| AU (1) | AU2015209133B2 (OSRAM) |
| BR (1) | BR112016017112A2 (OSRAM) |
| CA (1) | CA2937655C (OSRAM) |
| IL (1) | IL246879B (OSRAM) |
| MX (1) | MX373818B (OSRAM) |
| RU (2) | RU2019107011A (OSRAM) |
| WO (1) | WO2015112888A1 (OSRAM) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BR112016017112A2 (pt) | 2014-01-24 | 2017-08-08 | Ai Therapeutics Inc | Composições de apilimod e métodos de uso das mesmas |
| JP6705828B2 (ja) * | 2014-11-07 | 2020-06-03 | エイアイ・セラピューティクス・インコーポレーテッド | 腎癌の処置に使用するためのアピリモド |
| PT3215157T (pt) | 2014-11-07 | 2019-07-12 | Ai Therapeutics Inc | Apilimod para utilização no tratamento de melanoma |
| US10729694B2 (en) | 2015-01-23 | 2020-08-04 | AI Therapeutics, Inc. | Anti-viral compositions containing PIKfyve inhibitors and use thereof |
| WO2016160102A1 (en) * | 2015-03-31 | 2016-10-06 | Lam Therapeutics, Inc. | Active metabolites of apilimod and uses thereof |
| TWI746449B (zh) | 2015-07-20 | 2021-11-21 | 美商Ａｉ治療公司 | 使用阿吡莫德治療癌症之方法 |
| WO2017127661A1 (en) * | 2016-01-21 | 2017-07-27 | Lam Therapeutics, Inc. | Biomarkers for treating cancer with apilimod |
| KR20180015441A (ko) | 2016-08-03 | 2018-02-13 | 엘지전자 주식회사 | 롤리 키보드 |
| CA3034453A1 (en) * | 2016-08-25 | 2018-03-01 | AI Therapeutics, Inc. | Compositions comprising pikfyve inhibitors and methods related to inhibition of rank signaling |
| WO2019164861A1 (en) * | 2018-02-21 | 2019-08-29 | AI Therapeutics, Inc. | Combination therapy with apilimod and glutamatergic agents |
| CN108743947B (zh) * | 2018-07-04 | 2020-12-15 | 复旦大学附属肿瘤医院 | 一种治疗b细胞淋巴瘤的药物组合物 |
| CN110496128B (zh) * | 2019-09-23 | 2022-09-30 | 吉林大学 | 利培酮或帕潘立酮在制备治疗弥漫性大b细胞淋巴瘤的药物中的应用 |
| JP7744350B2 (ja) | 2020-01-13 | 2025-09-25 | バージ アナリティクス，インコーポレイテッド | 置換ピラゾロ－ピリミジンおよびその使用 |
| JP2024521449A (ja) * | 2021-06-11 | 2024-05-31 | オルフアイ セラピューティクス インコーポレイテッド | 安定化されたアピリモドの組成物およびその使用方法 |
Family Cites Families (39)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5210015A (en) | 1990-08-06 | 1993-05-11 | Hoffman-La Roche Inc. | Homogeneous assay system using the nuclease activity of a nucleic acid polymerase |
| PT728218E (pt) | 1993-11-12 | 2008-04-08 | Phri Properties Inc | Sondas de hibridação para detecção de ácidos nucleicos, troncos universais, métodos e estojos |
| US6693097B2 (en) | 2001-11-30 | 2004-02-17 | Synta Pharmaceuticals Corp. | Pyrimidine compounds |
| AU2005213324B2 (en) | 2004-02-06 | 2011-06-09 | Biogen Idec Ma Inc. | Methods and compositions for treating tumors and metastatic disease |
| WO2005112938A2 (en) | 2004-04-13 | 2005-12-01 | Synta Pharmaceuticals Corp. | Disalt inhibitors of il-12 production |
| EP1791544A4 (en) * | 2004-09-08 | 2007-09-12 | Chelsea Therapeutics Inc | CHINAZOLINE DERIVATIVES AS METABOLIC INERT ANTIFOLATE |
| US7923557B2 (en) | 2004-11-10 | 2011-04-12 | Synta Pharmaceuticals Corporation | Process for preparing trisubstituted pyrimidine compounds |
| US7863270B2 (en) | 2005-05-13 | 2011-01-04 | Synta Pharmaceuticals Corp. | IL-12 modulatory compounds |
| WO2006128129A2 (en) * | 2005-05-26 | 2006-11-30 | Synta Pharmaceuticals Corp. | Method for treating cancer |
| KR20080078668A (ko) | 2005-11-17 | 2008-08-27 | 오에스아이 파마슈티컬스, 인코포레이티드 | 융합된 바이사이클릭 ｍＴＯＲ 억제자 |
| AR057960A1 (es) | 2005-12-02 | 2007-12-26 | Osi Pharm Inc | Inhibidores de proteina quinasa biciclicos |
| JP5156644B2 (ja) | 2006-01-25 | 2013-03-06 | オーエスアイ・フアーマシユーテイカルズ・エル・エル・シー | 不飽和ｍＴＯＲ阻害剤 |
| JP5215300B2 (ja) | 2006-07-12 | 2013-06-19 | ユニバーシティ オブ テネシー リサーチ ファウンデーション | 置換アシルアニリドおよびそれらの使用方法 |
| US8173647B2 (en) | 2007-02-06 | 2012-05-08 | Gordana Atallah | PI 3-kinase inhibitors and methods of their use |
| RU2438664C2 (ru) | 2007-05-15 | 2012-01-10 | Пирамал Лайф Сайнсиз Лимитед | Синергическая фармацевтическая комбинация для лечения рака |
| DE102007036076A1 (de) | 2007-08-01 | 2009-02-05 | Bayer Healthcare Aktiengesellschaft | Dipeptoid-Produgs und ihre Verwendung |
| US8193182B2 (en) | 2008-01-04 | 2012-06-05 | Intellikine, Inc. | Substituted isoquinolin-1(2H)-ones, and methods of use thereof |
| JP5258331B2 (ja) * | 2008-03-03 | 2013-08-07 | ロート製薬株式会社 | 光安定性が改善されたニューキノロン系抗菌剤含有医薬組成物 |
| US20110224223A1 (en) | 2008-07-08 | 2011-09-15 | The Regents Of The University Of California, A California Corporation | MTOR Modulators and Uses Thereof |
| EP3023426A1 (en) | 2008-07-17 | 2016-05-25 | Critical Outcome Technologies, Inc. | Thiosemicarbazone inhibitor compounds and cancer treatment methods |
| CN102844023B (zh) * | 2010-03-08 | 2016-01-20 | 索隆-基特林癌症研究协会 | Cdc7激酶抑制剂以及其用途 |
| CN106963741A (zh) | 2010-03-29 | 2017-07-21 | Ea制药株式会社 | 含有苯基丙氨酸衍生物的医药制剂 |
| US8402515B2 (en) | 2010-05-06 | 2013-03-19 | Jonathan Weizman | Apparatus and method for establishing a peer-to-peer communication session with a client device |
| US20110287018A1 (en) * | 2010-05-19 | 2011-11-24 | Philip Bosch | Methods of Treating Interstitial Cystitis |
| US8709419B2 (en) | 2010-08-17 | 2014-04-29 | Hoffmann-La Roche, Inc. | Combination therapy |
| UA109557C2 (uk) * | 2010-11-19 | 2015-09-10 | Похідні 2-піперазин-1-іл-4h-1,3-бензотіазин-4-ону та їх застосування для лікування інфекцій у ссавців | |
| WO2013152342A1 (en) | 2012-04-06 | 2013-10-10 | OSI Pharmaceuticals, LLC | Anti-cancer mtor inhibitor and anti-androgen combination |
| US8940742B2 (en) * | 2012-04-10 | 2015-01-27 | Infinity Pharmaceuticals, Inc. | Heterocyclic compounds and uses thereof |
| WO2013173223A1 (en) | 2012-05-15 | 2013-11-21 | Bristol-Myers Squibb Company | Cancer immunotherapy by disrupting pd-1/pd-l1 signaling |
| WO2014055913A1 (en) | 2012-10-05 | 2014-04-10 | Cerulean Pharma Inc. | Treatment of cancer |
| US9295731B2 (en) | 2013-04-01 | 2016-03-29 | Mark Quang Nguyen | Cleavable drug conjugates, compositions thereof and methods of use |
| BR112016017112A2 (pt) | 2014-01-24 | 2017-08-08 | Ai Therapeutics Inc | Composições de apilimod e métodos de uso das mesmas |
| PT3215157T (pt) | 2014-11-07 | 2019-07-12 | Ai Therapeutics Inc | Apilimod para utilização no tratamento de melanoma |
| JP6705828B2 (ja) | 2014-11-07 | 2020-06-03 | エイアイ・セラピューティクス・インコーポレーテッド | 腎癌の処置に使用するためのアピリモド |
| WO2016126707A1 (en) | 2015-02-03 | 2016-08-11 | Lam Therapeutics, Inc. | Apilimod compositions and methods for using same |
| WO2016160102A1 (en) | 2015-03-31 | 2016-10-06 | Lam Therapeutics, Inc. | Active metabolites of apilimod and uses thereof |
| TWI746449B (zh) | 2015-07-20 | 2021-11-21 | 美商Ａｉ治療公司 | 使用阿吡莫德治療癌症之方法 |
| AU2019299234A1 (en) | 2018-07-05 | 2021-01-14 | Mayo Foundation For Medical Education And Research | PIKfyve inhibitors |
| AR119934A1 (es) | 2019-09-12 | 2022-01-19 | Ai Therapeutics Inc | Inhibidores de pikfyve para terapia contra el cáncer |
-
2015
- 2015-01-23 BR BR112016017112A patent/BR112016017112A2/pt not_active Application Discontinuation
- 2015-01-23 KR KR1020167022474A patent/KR102320190B1/ko not_active Expired - Fee Related
- 2015-01-23 RU RU2019107011A patent/RU2019107011A/ru unknown
- 2015-01-23 US US15/113,154 patent/US10179135B2/en active Active
- 2015-01-23 WO PCT/US2015/012733 patent/WO2015112888A1/en not_active Ceased
- 2015-01-23 JP JP2016548172A patent/JP6855243B2/ja not_active Expired - Fee Related
- 2015-01-23 CA CA2937655A patent/CA2937655C/en active Active
- 2015-01-23 RU RU2016134406A patent/RU2016134406A/ru not_active Application Discontinuation
- 2015-01-23 EP EP15740043.3A patent/EP3096757B1/en active Active
- 2015-01-23 CN CN201580016018.3A patent/CN106659716B/zh active Active
- 2015-01-23 AU AU2015209133A patent/AU2015209133B2/en not_active Ceased
- 2015-01-23 MX MX2016009590A patent/MX373818B/es active IP Right Grant
-
2016
- 2016-07-21 IL IL246879A patent/IL246879B/en active IP Right Grant
-
2018
- 2018-11-16 US US16/193,045 patent/US20190183902A1/en not_active Abandoned
-
2019
- 2019-12-27 US US16/728,566 patent/US11266654B2/en active Active
-
2020
- 2020-12-04 JP JP2020201440A patent/JP2021046430A/ja active Pending
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