|
US4469863A
(en)
|
1980-11-12 |
1984-09-04 |
Ts O Paul O P |
Nonionic nucleic acid alkyl and aryl phosphonates and processes for manufacture and use thereof
|
|
US5034506A
(en)
|
1985-03-15 |
1991-07-23 |
Anti-Gene Development Group |
Uncharged morpholino-based polymers having achiral intersubunit linkages
|
|
US5235033A
(en)
|
1985-03-15 |
1993-08-10 |
Anti-Gene Development Group |
Alpha-morpholino ribonucleoside derivatives and polymers thereof
|
|
US5216141A
(en)
|
1988-06-06 |
1993-06-01 |
Benner Steven A |
Oligonucleotide analogs containing sulfur linkages
|
|
GB8822228D0
(en)
|
1988-09-21 |
1988-10-26 |
Southern E M |
Support-bound oligonucleotides
|
|
US5744101A
(en)
|
1989-06-07 |
1998-04-28 |
Affymax Technologies N.V. |
Photolabile nucleoside protecting groups
|
|
US5143854A
(en)
|
1989-06-07 |
1992-09-01 |
Affymax Technologies N.V. |
Large scale photolithographic solid phase synthesis of polypeptides and receptor binding screening thereof
|
|
DE3924454A1
(de)
|
1989-07-24 |
1991-02-07 |
Cornelis P Prof Dr Hollenberg |
Die anwendung von dna und dna-technologie fuer die konstruktion von netzwerken zur verwendung in der chip-konstruktion und chip-produktion (dna chips)
|
|
US5252743A
(en)
|
1989-11-13 |
1993-10-12 |
Affymax Technologies N.V. |
Spatially-addressable immobilization of anti-ligands on surfaces
|
|
US5602240A
(en)
|
1990-07-27 |
1997-02-11 |
Ciba Geigy Ag. |
Backbone modified oligonucleotide analogs
|
|
US5386023A
(en)
|
1990-07-27 |
1995-01-31 |
Isis Pharmaceuticals |
Backbone modified oligonucleotide analogs and preparation thereof through reductive coupling
|
|
EP0773227A1
(en)
|
1991-09-18 |
1997-05-14 |
Affymax Technologies N.V. |
Diverse collections of oligomers in use to prepare drugs, diagnostic reagents, pesticides or herbicides
|
|
ATE293011T1
(de)
|
1991-11-22 |
2005-04-15 |
Affymetrix Inc A Delaware Corp |
Kombinatorische strategien für die polymersynthese
|
|
US5324633A
(en)
|
1991-11-22 |
1994-06-28 |
Affymax Technologies N.V. |
Method and apparatus for measuring binding affinity
|
|
US5644048A
(en)
|
1992-01-10 |
1997-07-01 |
Isis Pharmaceuticals, Inc. |
Process for preparing phosphorothioate oligonucleotides
|
|
ATE278807T1
(de)
|
1992-02-19 |
2004-10-15 |
New York Health Res Inst |
Neue anordnungen von oligonukleotiden und ihr nutzen zum sortieren, isolieren, sequenzierung und manipulieren von nukleinsäuren
|
|
US5583211A
(en)
|
1992-10-29 |
1996-12-10 |
Beckman Instruments, Inc. |
Surface activated organic polymers useful for location - specific attachment of nucleic acids, peptides, proteins and oligosaccharides
|
|
US5491074A
(en)
|
1993-04-01 |
1996-02-13 |
Affymax Technologies Nv |
Association peptides
|
|
US5858659A
(en)
|
1995-11-29 |
1999-01-12 |
Affymetrix, Inc. |
Polymorphism detection
|
|
US5472672A
(en)
|
1993-10-22 |
1995-12-05 |
The Board Of Trustees Of The Leland Stanford Junior University |
Apparatus and method for polymer synthesis using arrays
|
|
US5429807A
(en)
|
1993-10-28 |
1995-07-04 |
Beckman Instruments, Inc. |
Method and apparatus for creating biopolymer arrays on a solid support surface
|
|
US6090555A
(en)
|
1997-12-11 |
2000-07-18 |
Affymetrix, Inc. |
Scanned image alignment systems and methods
|
|
US5578832A
(en)
|
1994-09-02 |
1996-11-26 |
Affymetrix, Inc. |
Method and apparatus for imaging a sample on a device
|
|
US5637684A
(en)
|
1994-02-23 |
1997-06-10 |
Isis Pharmaceuticals, Inc. |
Phosphoramidate and phosphorothioamidate oligomeric compounds
|
|
DE69503126T2
(de)
|
1994-05-05 |
1998-11-12 |
Beckman Instruments Inc |
Repetitive oligonukleotide matrix
|
|
US5571639A
(en)
|
1994-05-24 |
1996-11-05 |
Affymax Technologies N.V. |
Computer-aided engineering system for design of sequence arrays and lithographic masks
|
|
US5807522A
(en)
|
1994-06-17 |
1998-09-15 |
The Board Of Trustees Of The Leland Stanford Junior University |
Methods for fabricating microarrays of biological samples
|
|
US5556752A
(en)
|
1994-10-24 |
1996-09-17 |
Affymetrix, Inc. |
Surface-bound, unimolecular, double-stranded DNA
|
|
US5795716A
(en)
|
1994-10-21 |
1998-08-18 |
Chee; Mark S. |
Computer-aided visualization and analysis system for sequence evaluation
|
|
US5599695A
(en)
|
1995-02-27 |
1997-02-04 |
Affymetrix, Inc. |
Printing molecular library arrays using deprotection agents solely in the vapor phase
|
|
US5624711A
(en)
|
1995-04-27 |
1997-04-29 |
Affymax Technologies, N.V. |
Derivatization of solid supports and methods for oligomer synthesis
|
|
US5545531A
(en)
|
1995-06-07 |
1996-08-13 |
Affymax Technologies N.V. |
Methods for making a device for concurrently processing multiple biological chip assays
|
|
US5968740A
(en)
|
1995-07-24 |
1999-10-19 |
Affymetrix, Inc. |
Method of Identifying a Base in a Nucleic Acid
|
|
EP0852004B1
(en)
|
1995-10-11 |
2011-01-19 |
Luminex Corporation |
Multiplexed analysis of clinical specimens
|
|
US5658734A
(en)
|
1995-10-17 |
1997-08-19 |
International Business Machines Corporation |
Process for synthesizing chemical compounds
|
|
US6022963A
(en)
|
1995-12-15 |
2000-02-08 |
Affymetrix, Inc. |
Synthesis of oligonucleotide arrays using photocleavable protecting groups
|
|
EP0902885A4
(en)
|
1996-05-16 |
2006-09-27 |
Affymetrix Inc |
SYSTEMS AND METHODS FOR DETECTION OF BRANDED PRODUCTS
|
|
US5786146A
(en)
|
1996-06-03 |
1998-07-28 |
The Johns Hopkins University School Of Medicine |
Method of detection of methylated nucleic acid using agents which modify unmethylated cytosine and distinguishing modified methylated and non-methylated nucleic acids
|
|
WO1998020967A1
(en)
|
1996-11-14 |
1998-05-22 |
Affymetrix, Inc. |
Chemical amplification for the synthesis of patterned arrays
|
|
US6297006B1
(en)
|
1997-01-16 |
2001-10-02 |
Hyseq, Inc. |
Methods for sequencing repetitive sequences and for determining the order of sequence subfragments
|
|
US6023540A
(en)
|
1997-03-14 |
2000-02-08 |
Trustees Of Tufts College |
Fiber optic sensor with encoded microspheres
|
|
US6327410B1
(en)
|
1997-03-14 |
2001-12-04 |
The Trustees Of Tufts College |
Target analyte sensors utilizing Microspheres
|
|
US6033860A
(en)
|
1997-10-31 |
2000-03-07 |
Affymetrix, Inc. |
Expression profiles in adult and fetal organs
|
|
US6087102A
(en)
|
1998-01-07 |
2000-07-11 |
Clontech Laboratories, Inc. |
Polymeric arrays and methods for their use in binding assays
|
|
US6428752B1
(en)
|
1998-05-14 |
2002-08-06 |
Affymetrix, Inc. |
Cleaning deposit devices that form microarrays and the like
|
|
US6287776B1
(en)
|
1998-02-02 |
2001-09-11 |
Signature Bioscience, Inc. |
Method for detecting and classifying nucleic acid hybridization
|
|
WO1999039817A1
(en)
|
1998-02-06 |
1999-08-12 |
Affymetrix, Inc. |
Method of quality control in manufacturing processes
|
|
JP3944996B2
(ja)
|
1998-03-05 |
2007-07-18 |
株式会社日立製作所 |
Ｄｎａプローブアレー
|
|
US6031078A
(en)
|
1998-06-16 |
2000-02-29 |
Millennium Pharmaceuticals, Inc. |
MTbx protein and nucleic acid molecules and uses therefor
|
|
US6277628B1
(en)
|
1998-10-02 |
2001-08-21 |
Incyte Genomics, Inc. |
Linear microarrays
|
|
US6355431B1
(en)
|
1999-04-20 |
2002-03-12 |
Illumina, Inc. |
Detection of nucleic acid amplification reactions using bead arrays
|
|
US20030215821A1
(en)
|
1999-04-20 |
2003-11-20 |
Kevin Gunderson |
Detection of nucleic acid reactions on bead arrays
|
|
CA2370976C
(en)
|
1999-04-20 |
2009-10-20 |
Illumina, Inc. |
Detection of nucleic acid reactions on bead arrays
|
|
US7582420B2
(en)
|
2001-07-12 |
2009-09-01 |
Illumina, Inc. |
Multiplex nucleic acid reactions
|
|
US6913884B2
(en)
|
2001-08-16 |
2005-07-05 |
Illumina, Inc. |
Compositions and methods for repetitive use of genomic DNA
|
|
JP2003521252A
(ja)
|
2000-02-07 |
2003-07-15 |
イルミナ インコーポレイテッド |
ユニバーサルプライミングを用いる核酸検出方法
|
|
US7955794B2
(en)
|
2000-09-21 |
2011-06-07 |
Illumina, Inc. |
Multiplex nucleic acid reactions
|
|
US20040121364A1
(en)
|
2000-02-07 |
2004-06-24 |
Mark Chee |
Multiplex nucleic acid reactions
|
|
US7611869B2
(en)
|
2000-02-07 |
2009-11-03 |
Illumina, Inc. |
Multiplexed methylation detection methods
|
|
US6770441B2
(en)
|
2000-02-10 |
2004-08-03 |
Illumina, Inc. |
Array compositions and methods of making same
|
|
JP2001244419A
(ja)
*
|
2000-02-28 |
2001-09-07 |
Hitachi Ltd |
高周波モジュール及び移動体検知モジュール
|
|
US6489606B1
(en)
|
2000-04-07 |
2002-12-03 |
Cidra Corporation |
Bragg grating sensor system with spectral response or code division multiplexing
|
|
EP1368460B1
(en)
*
|
2000-07-07 |
2007-10-31 |
Visigen Biotechnologies, Inc. |
Real-time sequence determination
|
|
US20040018491A1
(en)
|
2000-10-26 |
2004-01-29 |
Kevin Gunderson |
Detection of nucleic acid reactions on bead arrays
|
|
KR20040064275A
(ko)
*
|
2001-11-09 |
2004-07-16 |
소스 프리시전 메디슨, 인코포레이티드 |
유전자 발현 프로파일을 이용한 질병의 동정, 모니터링,치료 및 생물학적 상태의 확인
|
|
US8288641B2
(en)
*
|
2001-12-27 |
2012-10-16 |
Intel Corporation |
Portable hand-held music synthesizer and networking method and apparatus
|
|
US20040029151A1
(en)
*
|
2002-04-09 |
2004-02-12 |
Affymetrix, Inc. |
Molecular genetic profiling of gleason grades 3 and 4/5 prostate cancer
|
|
US7164533B2
(en)
|
2003-01-22 |
2007-01-16 |
Cyvera Corporation |
Hybrid random bead/chip based microarray
|
|
US7126755B2
(en)
|
2002-09-12 |
2006-10-24 |
Moon John A |
Method and apparatus for labeling using diffraction grating-based encoded optical identification elements
|
|
US7441703B2
(en)
|
2002-08-20 |
2008-10-28 |
Illumina, Inc. |
Optical reader for diffraction grating-based encoded optical identification elements
|
|
US20050227252A1
(en)
|
2002-08-20 |
2005-10-13 |
Moon John A |
Diffraction grating-based encoded articles for multiplexed experiments
|
|
AU2003265583C1
(en)
|
2002-08-20 |
2009-05-21 |
Cyvera Corporation |
Diffraction grating-based optical identification element
|
|
WO2004024328A1
(en)
|
2002-09-12 |
2004-03-25 |
Cyvera Corporation |
Method and apparatus for aligning elongated microbeads in order to interrogate the same
|
|
US20040259105A1
(en)
|
2002-10-03 |
2004-12-23 |
Jian-Bing Fan |
Multiplex nucleic acid analysis using archived or fixed samples
|
|
US20040219575A1
(en)
*
|
2002-12-26 |
2004-11-04 |
Toomas Neuman |
Methods and compositions for the diagnosis, prognosis, and treatment of cancer
|
|
US8081792B2
(en)
|
2003-08-20 |
2011-12-20 |
Illumina, Inc. |
Fourier scattering methods for encoding microbeads and methods and apparatus for reading the same
|
|
US20050181394A1
(en)
|
2003-06-20 |
2005-08-18 |
Illumina, Inc. |
Methods and compositions for whole genome amplification and genotyping
|
|
EP1673614A1
(en)
|
2003-10-01 |
2006-06-28 |
CiDra Corporation |
Optical reader for diffraction grating-based encoded optical identification elements
|
|
US20060023310A1
(en)
|
2004-02-19 |
2006-02-02 |
Putnam Martin A |
Optical identification element using separate or partially overlapped diffraction gratings
|
|
US7339165B2
(en)
|
2004-07-09 |
2008-03-04 |
Hamilton Sundstrand Corporation |
Dual outlet pyrolyzer for biological agent detection system
|
|
CA2491067A1
(en)
|
2004-12-24 |
2006-06-24 |
Stichting Katholieke Universiteit |
Mrna rations in urinary sediments and/or urine as a prognostic marker for prostate cancer
|
|
US7914988B1
(en)
|
2006-03-31 |
2011-03-29 |
Illumina, Inc. |
Gene expression profiles to predict relapse of prostate cancer
|
|
US8262900B2
(en)
|
2006-12-14 |
2012-09-11 |
Life Technologies Corporation |
Methods and apparatus for measuring analytes using large scale FET arrays
|
|
KR20100089060A
(ko)
|
2007-10-04 |
2010-08-11 |
할싸이언 몰레큘러 |
전자 현미경으로 핵산 중합체를 시퀀싱하는 방법
|
|
US20120329713A1
(en)
|
2008-02-21 |
2012-12-27 |
Klem Robert E |
Method for determining likelihood of clinical recurrence or clinically stable disease of prostate cancer after radical prostatectomy
|
|
US20110236903A1
(en)
*
|
2008-12-04 |
2011-09-29 |
Mcclelland Michael |
Materials and methods for determining diagnosis and prognosis of prostate cancer
|
|
JP5718319B2
(ja)
*
|
2009-05-14 |
2015-05-13 |
ネステク ソシエテ アノニム |
Ｈｅｒ２標的化療法に対する乳癌細胞の感受性を決定するためのバイオマーカー
|
|
TWM395976U
(en)
*
|
2010-06-30 |
2011-01-01 |
Tsung-Hung Wu |
Electret electroacoustic transducer
|
|
IL243203A
(en)
*
|
2010-07-27 |
2017-04-30 |
Genomic Health Inc |
Method for using gene expression to determine prognosis of prostate cancer
|
|
WO2012115885A1
(en)
*
|
2011-02-22 |
2012-08-30 |
Caris Life Sciences Luxembourg Holdings, S.A.R.L. |
Circulating biomarkers
|
|
CA2838736A1
(en)
*
|
2011-06-07 |
2012-12-13 |
Caris Mpi, Inc. |
Molecular profiling for cancer
|
|
HK1201881A1
(en)
|
2012-01-31 |
2015-09-11 |
Genomic Health, Inc. |
Gene expression profile algorithm and test for determining prognosis of prostate cancer
|
|
US20130323739A1
(en)
|
2012-06-05 |
2013-12-05 |
Iris International, Inc. |
Method for determining recurrence or stable disease after treatment for prostate cancer
|
|
WO2014022594A1
(en)
|
2012-07-31 |
2014-02-06 |
Daniel Mercola |
Stroma biomarkers for prostate cancer prognosis
|
|
JP6666852B2
(ja)
|
2014-01-16 |
2020-03-18 |
イルミナ インコーポレイテッド |
前立腺がん再発の予後に関する遺伝子発現パネル
|