JP2017503016A5 - - Google Patents
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- Publication number
- JP2017503016A5 JP2017503016A5 JP2016560857A JP2016560857A JP2017503016A5 JP 2017503016 A5 JP2017503016 A5 JP 2017503016A5 JP 2016560857 A JP2016560857 A JP 2016560857A JP 2016560857 A JP2016560857 A JP 2016560857A JP 2017503016 A5 JP2017503016 A5 JP 2017503016A5
- Authority
- JP
- Japan
- Prior art keywords
- compound
- diffractometer
- determined
- powder
- item
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
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- MZBLZLWXUBZHSL-FZNJKFJKSA-N CC[C@H]([C@H](C1)Oc2nc(cc(cc3)OC)c3nc2C(CCCC[C@H](C2)[C@@H]2OC(N[C@H]2C(C)(C)C)=O)(F)F)[C@@H](C(N[C@](C3)([C@@H]3C(F)F)C(NS(C3(C)CC3)(=O)=O)=O)=O)N1C2=O Chemical compound CC[C@H]([C@H](C1)Oc2nc(cc(cc3)OC)c3nc2C(CCCC[C@H](C2)[C@@H]2OC(N[C@H]2C(C)(C)C)=O)(F)F)[C@@H](C(N[C@](C3)([C@@H]3C(F)F)C(NS(C3(C)CC3)(=O)=O)=O)=O)N1C2=O MZBLZLWXUBZHSL-FZNJKFJKSA-N 0.000 description 3
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361920427P | 2013-12-23 | 2013-12-23 | |
| US61/920,427 | 2013-12-23 | ||
| PCT/US2014/071310 WO2015100144A1 (en) | 2013-12-23 | 2014-12-18 | Crystalline forms of a macrocyclic hcv ns3 inhibiting tripeptide |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019020540A Division JP2019089819A (ja) | 2013-12-23 | 2019-02-07 | 大環状ｈｃｖ ｎｓ３阻害トリペプチドの結晶形態 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2017503016A JP2017503016A (ja) | 2017-01-26 |
| JP2017503016A5 true JP2017503016A5 (cg-RX-API-DMAC7.html) | 2018-01-18 |
| JP6568541B2 JP6568541B2 (ja) | 2019-08-28 |
Family
ID=52282995
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016560857A Expired - Fee Related JP6568541B2 (ja) | 2013-12-23 | 2014-12-18 | 大環状ｈｃｖ ｎｓ３阻害トリペプチドの結晶形態 |
| JP2019020540A Pending JP2019089819A (ja) | 2013-12-23 | 2019-02-07 | 大環状ｈｃｖ ｎｓ３阻害トリペプチドの結晶形態 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019020540A Pending JP2019089819A (ja) | 2013-12-23 | 2019-02-07 | 大環状ｈｃｖ ｎｓ３阻害トリペプチドの結晶形態 |
Country Status (12)
| Country | Link |
|---|---|
| US (2) | US9562058B2 (cg-RX-API-DMAC7.html) |
| EP (1) | EP3087086B1 (cg-RX-API-DMAC7.html) |
| JP (2) | JP6568541B2 (cg-RX-API-DMAC7.html) |
| AR (1) | AR098958A1 (cg-RX-API-DMAC7.html) |
| AU (1) | AU2014370124A1 (cg-RX-API-DMAC7.html) |
| CA (1) | CA2934049A1 (cg-RX-API-DMAC7.html) |
| ES (1) | ES2708993T3 (cg-RX-API-DMAC7.html) |
| NZ (1) | NZ720887A (cg-RX-API-DMAC7.html) |
| PT (1) | PT3087086T (cg-RX-API-DMAC7.html) |
| TW (1) | TW201609752A (cg-RX-API-DMAC7.html) |
| UY (1) | UY35918A (cg-RX-API-DMAC7.html) |
| WO (1) | WO2015100144A1 (cg-RX-API-DMAC7.html) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2014370125B2 (en) | 2013-12-23 | 2017-11-16 | Gilead Sciences, Inc. | Synthesis of a macrocyclic HCV NS3 inhibiting tripeptide |
| JP7381190B2 (ja) | 2014-12-26 | 2023-11-15 | エモリー・ユニバーシテイ | Ｎ４－ヒドロキシシチジン及び誘導体並びにそれに関連する抗ウイルス用途 |
| JOP20170127A1 (ar) * | 2016-06-02 | 2017-12-02 | Gilead Pharmasset Llc | صيغة مشتركة مكونة من ثلاث مركبات مضادة للفيروسات |
| PT3706762T (pt) | 2017-12-07 | 2024-12-05 | Univ Emory | N4-hidroxicitidina e derivados e utilizações antivirais relacionadas com os mesmos |
| CN115417803B (zh) * | 2022-08-30 | 2023-10-03 | 四川同晟生物医药有限公司 | 乌帕替尼中间体(3r,4s)-1-苄氧羰基-4-乙基吡咯烷-3-羧酸的合成方法 |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5023252A (en) | 1985-12-04 | 1991-06-11 | Conrex Pharmaceutical Corporation | Transdermal and trans-membrane delivery of drugs |
| US5001139A (en) | 1987-06-12 | 1991-03-19 | American Cyanamid Company | Enchancers for the transdermal flux of nivadipine |
| US4992445A (en) | 1987-06-12 | 1991-02-12 | American Cyanamid Co. | Transdermal delivery of pharmaceuticals |
| CL2008003384A1 (es) * | 2007-11-14 | 2009-12-11 | Enanta Pharm Inc | Compuestos derivados de quinoxalina macrocíclica, inhibidores de serina proteasa; composicion farmaceutica que los comprende; y su uso en el tratamiento de la hepatitis c. |
| PT2540350E (pt) * | 2008-07-22 | 2014-08-27 | Merck Sharp & Dohme | Combinações de um composto de quinoxalina macrocílico o qual é um inibidor da protease ns3 do hcv com outros agentes do hcv |
| JP5857053B2 (ja) * | 2010-09-21 | 2016-02-10 | エナンタ ファーマシューティカルズ インコーポレイテッド | 大環式プロリン由来ｈｃｖセリンプロテアーゼ阻害剤 |
| EP2618665A4 (en) * | 2010-09-21 | 2014-08-20 | Merck Sharp & Dohme | HCV NS3 proteinase inhibitor |
| CN105837584B (zh) | 2011-11-16 | 2018-07-13 | 吉利德制药有限责任公司 | 作为抗病毒化合物的缩合的咪唑基咪唑 |
| UA119315C2 (uk) * | 2012-07-03 | 2019-06-10 | Гіліад Фармассет Елелсі | Інгібітори вірусу гепатиту с |
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2014
- 2014-12-18 JP JP2016560857A patent/JP6568541B2/ja not_active Expired - Fee Related
- 2014-12-18 NZ NZ720887A patent/NZ720887A/en not_active IP Right Cessation
- 2014-12-18 ES ES14824322T patent/ES2708993T3/es active Active
- 2014-12-18 US US14/575,966 patent/US9562058B2/en active Active
- 2014-12-18 PT PT14824322T patent/PT3087086T/pt unknown
- 2014-12-18 WO PCT/US2014/071310 patent/WO2015100144A1/en not_active Ceased
- 2014-12-18 AU AU2014370124A patent/AU2014370124A1/en not_active Abandoned
- 2014-12-18 CA CA2934049A patent/CA2934049A1/en not_active Abandoned
- 2014-12-18 EP EP14824322.3A patent/EP3087086B1/en active Active
- 2014-12-22 TW TW103144805A patent/TW201609752A/zh unknown
- 2014-12-23 UY UY0001035918A patent/UY35918A/es not_active Application Discontinuation
- 2014-12-23 AR ARP140104909A patent/AR098958A1/es unknown
-
2016
- 2016-12-21 US US15/387,318 patent/US9862728B2/en active Active
-
2019
- 2019-02-07 JP JP2019020540A patent/JP2019089819A/ja active Pending