JP2017502039A5 - - Google Patents
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- Publication number
- JP2017502039A5 JP2017502039A5 JP2016542216A JP2016542216A JP2017502039A5 JP 2017502039 A5 JP2017502039 A5 JP 2017502039A5 JP 2016542216 A JP2016542216 A JP 2016542216A JP 2016542216 A JP2016542216 A JP 2016542216A JP 2017502039 A5 JP2017502039 A5 JP 2017502039A5
- Authority
- JP
- Japan
- Prior art keywords
- compound
- formula
- nitrogen
- sulfur
- oxygen
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 0 CC(C)NCCC[n]1c(Sc(c(*)c2)cc3c2OCO3)nc2c(N)ncnc12 Chemical compound CC(C)NCCC[n]1c(Sc(c(*)c2)cc3c2OCO3)nc2c(N)ncnc12 0.000 description 12
- SUPVGFZUWFMATN-UHFFFAOYSA-N CC(C)NCCC[n]1c(Sc(c(I)c2)cc3c2OCO3)nc2c(N)ncnc12 Chemical compound CC(C)NCCC[n]1c(Sc(c(I)c2)cc3c2OCO3)nc2c(N)ncnc12 SUPVGFZUWFMATN-UHFFFAOYSA-N 0.000 description 2
- LMRKVKPRHROQRR-UHFFFAOYSA-N CCCCN1CCOCC1 Chemical compound CCCCN1CCOCC1 LMRKVKPRHROQRR-UHFFFAOYSA-N 0.000 description 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361919901P | 2013-12-23 | 2013-12-23 | |
| US61/919,901 | 2013-12-23 | ||
| PCT/US2014/072090 WO2015138039A1 (en) | 2013-12-23 | 2014-12-23 | Methods and reagents for radiolabeling |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2017502039A JP2017502039A (ja) | 2017-01-19 |
| JP2017502039A5 true JP2017502039A5 (enExample) | 2018-02-01 |
| JP6491214B2 JP6491214B2 (ja) | 2019-03-27 |
Family
ID=54072256
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016542216A Expired - Fee Related JP6491214B2 (ja) | 2013-12-23 | 2014-12-23 | 放射性標識のための方法および試薬 |
Country Status (13)
| Country | Link |
|---|---|
| US (3) | US9994573B2 (enExample) |
| EP (1) | EP3086792B1 (enExample) |
| JP (1) | JP6491214B2 (enExample) |
| KR (1) | KR102325454B1 (enExample) |
| CN (1) | CN106456645B (enExample) |
| AU (1) | AU2014386214B2 (enExample) |
| BR (1) | BR112016014758A8 (enExample) |
| CA (1) | CA2934850C (enExample) |
| IL (1) | IL246403B (enExample) |
| MX (1) | MX2016008418A (enExample) |
| RU (1) | RU2016128528A (enExample) |
| TW (1) | TWI673279B (enExample) |
| WO (1) | WO2015138039A1 (enExample) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2015138039A1 (en) | 2013-12-23 | 2015-09-17 | Memorial Sloan-Kettering Cancer Center | Methods and reagents for radiolabeling |
| MX387627B (es) * | 2014-09-17 | 2025-03-18 | Memorial Sloan Kettering Cancer Center | Formación de imágenes de inflamación e infección dirigida a hsp90 y terapia |
| WO2017002196A1 (ja) * | 2015-06-30 | 2017-01-05 | 株式会社日立国際電気 | 整合器及び整合方法 |
| KR102175125B1 (ko) * | 2018-12-28 | 2020-11-05 | 울산과학기술원 | 미토콘드리아 표적 Hsp90 억제제 기반 화합물 및 이를 포함하는 광역학 치료를 위한 약학적 조성물 |
| WO2022182731A1 (en) * | 2021-02-24 | 2022-09-01 | Samus Therapeutics, Inc. | Sn-labeling and radiolabeling of epichaperome inhibitors |
Family Cites Families (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4911920A (en) | 1986-07-30 | 1990-03-27 | Alcon Laboratories, Inc. | Sustained release, comfort formulation for glaucoma therapy |
| FR2588189B1 (fr) | 1985-10-03 | 1988-12-02 | Merck Sharp & Dohme | Composition pharmaceutique de type a transition de phase liquide-gel |
| JP2594486B2 (ja) | 1991-01-15 | 1997-03-26 | アルコン ラボラトリーズ インコーポレイテッド | 局所的眼薬組成物 |
| US5212162A (en) | 1991-03-27 | 1993-05-18 | Alcon Laboratories, Inc. | Use of combinations gelling polysaccharides and finely divided drug carrier substrates in topical ophthalmic compositions |
| US6309853B1 (en) | 1994-08-17 | 2001-10-30 | The Rockfeller University | Modulators of body weight, corresponding nucleic acids and proteins, and diagnostic and therapeutic uses thereof |
| US20070178537A1 (en) * | 2003-06-30 | 2007-08-02 | Sloan-Kettering Institute For Cancer Research | Assays for detection of bioactive compounds that interact with heat shock protein 90 |
| US7834181B2 (en) | 2005-02-01 | 2010-11-16 | Slaon-Kettering Institute For Cancer Research | Small-molecule Hsp90 inhibitors |
| US9403828B2 (en) | 2005-02-01 | 2016-08-02 | Sloan-Kettering Institute For Cancer Research | Small-molecule Hsp90 inhibitors |
| WO2007134298A2 (en) | 2006-05-12 | 2007-11-22 | Myriad Genetics, Inc. | Therapeutic compounds and their use in cancer |
| WO2008005937A2 (en) | 2006-06-30 | 2008-01-10 | Sloan-Kettering Institute For Cancer Research | Treatment of neurodegenerative diseases through inhibiton of hsp90 |
| KR101313804B1 (ko) | 2007-03-20 | 2013-10-01 | 쿠리스 인코퍼레이션 | Ｈｓｐ９０ 억제제로서의 융합된 아미노 피리딘 |
| NZ586129A (en) | 2007-11-14 | 2012-06-29 | Myrexis Inc | Therapeutic compounds and their use in treating diseases and disorders |
| JP5941407B2 (ja) | 2009-10-07 | 2016-06-29 | スローン − ケッタリング インスティチュート フォー キャンサー リサーチ | Ｈｓｐ９０阻害剤 |
| CN103596955B (zh) | 2011-04-05 | 2016-11-16 | 索隆-基特林癌症研究协会 | Hsp90抑制剂 |
| JP6266506B2 (ja) | 2011-04-05 | 2018-01-24 | スローン − ケッタリング インスティチュート フォー キャンサー リサーチ | Ｈｓｐ９０阻害物質 |
| BR112013027448A2 (pt) | 2011-04-28 | 2020-09-01 | Sloan-Kettering Institute For Cancer Research | terapia de combinação com hsp90 |
| EA201490230A1 (ru) | 2011-07-08 | 2014-06-30 | Слоан-Кеттеринг Инститьют Фор Кэнсер Рисерч | Применение меченых ингибиторов hsp90 |
| EP2972394A4 (en) * | 2013-03-15 | 2016-11-02 | Sloan Kettering Inst Cancer | HSP90-DESIGNING AND THERAPY |
| SG11201601542SA (en) | 2013-08-16 | 2016-04-28 | Sloan Kettering Inst Cancer | Selective grp94 inhibitors and uses thereof |
| WO2015138039A1 (en) | 2013-12-23 | 2015-09-17 | Memorial Sloan-Kettering Cancer Center | Methods and reagents for radiolabeling |
| MX387627B (es) | 2014-09-17 | 2025-03-18 | Memorial Sloan Kettering Cancer Center | Formación de imágenes de inflamación e infección dirigida a hsp90 y terapia |
| US20180280397A1 (en) | 2015-10-05 | 2018-10-04 | Memorial Sloan Kettering Cancer Center | Rational combination therapy for the treatment of cancer |
-
2014
- 2014-12-23 WO PCT/US2014/072090 patent/WO2015138039A1/en not_active Ceased
- 2014-12-23 TW TW103145077A patent/TWI673279B/zh not_active IP Right Cessation
- 2014-12-23 RU RU2016128528A patent/RU2016128528A/ru unknown
- 2014-12-23 CA CA2934850A patent/CA2934850C/en active Active
- 2014-12-23 MX MX2016008418A patent/MX2016008418A/es unknown
- 2014-12-23 CN CN201480076193.7A patent/CN106456645B/zh not_active Expired - Fee Related
- 2014-12-23 KR KR1020167019985A patent/KR102325454B1/ko not_active Expired - Fee Related
- 2014-12-23 JP JP2016542216A patent/JP6491214B2/ja not_active Expired - Fee Related
- 2014-12-23 AU AU2014386214A patent/AU2014386214B2/en not_active Ceased
- 2014-12-23 EP EP14885717.0A patent/EP3086792B1/en not_active Not-in-force
- 2014-12-23 US US15/107,229 patent/US9994573B2/en active Active
- 2014-12-23 BR BR112016014758A patent/BR112016014758A8/pt not_active Application Discontinuation
-
2016
- 2016-06-22 IL IL246403A patent/IL246403B/en active IP Right Grant
-
2018
- 2018-05-04 US US15/971,908 patent/US10329293B2/en active Active
-
2019
- 2019-04-26 US US16/396,496 patent/US10793570B2/en not_active Expired - Fee Related
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