JP2017501235A5 - - Google Patents
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- Publication number
- JP2017501235A5 JP2017501235A5 JP2016562082A JP2016562082A JP2017501235A5 JP 2017501235 A5 JP2017501235 A5 JP 2017501235A5 JP 2016562082 A JP2016562082 A JP 2016562082A JP 2016562082 A JP2016562082 A JP 2016562082A JP 2017501235 A5 JP2017501235 A5 JP 2017501235A5
- Authority
- JP
- Japan
- Prior art keywords
- iron
- iii
- torimarutoru
- formulation
- elemental
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 238000009472 formulation Methods 0.000 claims description 27
- 239000000203 mixture Substances 0.000 claims description 27
- XEEYBQQBJWHFJM-UHFFFAOYSA-N Iron Chemical compound [Fe] XEEYBQQBJWHFJM-UHFFFAOYSA-N 0.000 claims description 18
- 239000000546 pharmaceutical excipient Substances 0.000 claims description 11
- 206010022971 Iron Deficiencies Diseases 0.000 claims description 10
- 229910052742 iron Inorganic materials 0.000 claims description 9
- 208000007502 anemia Diseases 0.000 claims description 8
- HQKMJHAJHXVSDF-UHFFFAOYSA-L magnesium stearate Chemical compound [Mg+2].CCCCCCCCCCCCCCCCCC([O-])=O.CCCCCCCCCCCCCCCCCC([O-])=O HQKMJHAJHXVSDF-UHFFFAOYSA-L 0.000 claims description 8
- 208000022559 Inflammatory bowel disease Diseases 0.000 claims description 6
- 210000002784 stomach Anatomy 0.000 claims description 5
- WSVLPVUVIUVCRA-KPKNDVKVSA-N Alpha-lactose monohydrate Chemical compound O.O[C@@H]1[C@@H](O)[C@@H](O)[C@@H](CO)O[C@H]1O[C@@H]1[C@@H](CO)O[C@H](O)[C@H](O)[C@H]1O WSVLPVUVIUVCRA-KPKNDVKVSA-N 0.000 claims description 4
- WHNWPMSKXPGLAX-UHFFFAOYSA-N N-Vinyl-2-pyrrolidone Chemical compound C=CN1CCCC1=O WHNWPMSKXPGLAX-UHFFFAOYSA-N 0.000 claims description 4
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 claims description 4
- DBMJMQXJHONAFJ-UHFFFAOYSA-M Sodium laurylsulphate Chemical compound [Na+].CCCCCCCCCCCCOS([O-])(=O)=O DBMJMQXJHONAFJ-UHFFFAOYSA-M 0.000 claims description 4
- 235000021152 breakfast Nutrition 0.000 claims description 4
- 229940075614 colloidal silicon dioxide Drugs 0.000 claims description 4
- 229960000913 crospovidone Drugs 0.000 claims description 4
- 229960001021 lactose monohydrate Drugs 0.000 claims description 4
- 235000019359 magnesium stearate Nutrition 0.000 claims description 4
- 235000013809 polyvinylpolypyrrolidone Nutrition 0.000 claims description 4
- 229920000523 polyvinylpolypyrrolidone Polymers 0.000 claims description 4
- 235000019333 sodium laurylsulphate Nutrition 0.000 claims description 4
- 238000011282 treatment Methods 0.000 claims description 4
- 230000001154 acute effect Effects 0.000 claims description 3
- 239000002775 capsule Substances 0.000 claims description 3
- 208000037976 chronic inflammation Diseases 0.000 claims description 3
- 230000006020 chronic inflammation Effects 0.000 claims description 3
- 208000027866 inflammatory disease Diseases 0.000 claims description 3
- 230000002265 prevention Effects 0.000 claims description 3
- 206010009900 Colitis ulcerative Diseases 0.000 claims description 2
- 208000011231 Crohn disease Diseases 0.000 claims description 2
- 208000015710 Iron-Deficiency Anemia Diseases 0.000 claims description 2
- 201000006704 Ulcerative Colitis Diseases 0.000 claims description 2
- 238000012423 maintenance Methods 0.000 claims description 2
- VTLYFUHAOXGGBS-UHFFFAOYSA-N Fe3+ Chemical compound [Fe+3] VTLYFUHAOXGGBS-UHFFFAOYSA-N 0.000 claims 20
- 238000002360 preparation method Methods 0.000 claims 4
- 229940082629 iron antianemic preparations Drugs 0.000 claims 2
- 239000007963 capsule composition Substances 0.000 claims 1
- 238000011321 prophylaxis Methods 0.000 claims 1
- 238000000034 method Methods 0.000 description 2
- 102000001554 Hemoglobins Human genes 0.000 description 1
- 108010054147 Hemoglobins Proteins 0.000 description 1
- 230000035790 physiological processes and functions Effects 0.000 description 1
- 210000001995 reticulocyte Anatomy 0.000 description 1
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB201400171A GB201400171D0 (en) | 2014-01-06 | 2014-01-06 | Dosage regimen |
| GB1400171.3 | 2014-01-06 | ||
| GB1418708.2 | 2014-10-21 | ||
| GB201418708A GB201418708D0 (en) | 2014-10-21 | 2014-10-21 | Dosage regimen |
| PCT/IB2015/050098 WO2015101971A1 (en) | 2014-01-06 | 2015-01-06 | Dosage regimen of ferric trimaltol |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019072643A Division JP2019131592A (ja) | 2014-01-06 | 2019-04-05 | トリマルトール鉄（ｉｉｉ）の投与計画 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2017501235A JP2017501235A (ja) | 2017-01-12 |
| JP2017501235A5 true JP2017501235A5 (cg-RX-API-DMAC7.html) | 2017-09-28 |
| JP6556753B2 JP6556753B2 (ja) | 2019-08-07 |
Family
ID=52432872
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016562082A Active JP6556753B2 (ja) | 2014-01-06 | 2015-01-06 | トリマルトール鉄（ｉｉｉ）の投与計画 |
| JP2019072643A Withdrawn JP2019131592A (ja) | 2014-01-06 | 2019-04-05 | トリマルトール鉄（ｉｉｉ）の投与計画 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019072643A Withdrawn JP2019131592A (ja) | 2014-01-06 | 2019-04-05 | トリマルトール鉄（ｉｉｉ）の投与計画 |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US10179120B2 (cg-RX-API-DMAC7.html) |
| EP (1) | EP3091974B1 (cg-RX-API-DMAC7.html) |
| JP (2) | JP6556753B2 (cg-RX-API-DMAC7.html) |
| KR (1) | KR102351422B1 (cg-RX-API-DMAC7.html) |
| CN (2) | CN106413706A (cg-RX-API-DMAC7.html) |
| AU (1) | AU2015204192B2 (cg-RX-API-DMAC7.html) |
| BR (1) | BR112016015766A2 (cg-RX-API-DMAC7.html) |
| CA (1) | CA2934836C (cg-RX-API-DMAC7.html) |
| ES (1) | ES2785391T3 (cg-RX-API-DMAC7.html) |
| IL (1) | IL246613B (cg-RX-API-DMAC7.html) |
| SI (1) | SI3091974T1 (cg-RX-API-DMAC7.html) |
| WO (1) | WO2015101971A1 (cg-RX-API-DMAC7.html) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106413706A (zh) | 2014-01-06 | 2017-02-15 | 铁治疗控股公司 | 三麦芽酚铁的剂量方案 |
| GB201418710D0 (en) | 2014-10-21 | 2014-12-03 | Iron Therapeutics Holdings Ag | Dosage regimen |
| CN109071481B (zh) | 2016-03-31 | 2022-09-30 | 英国神盾Tx股份有限公司 | 用于由元素铁产生麦芽酚铁组合物的方法 |
| CN109310667B (zh) * | 2016-03-31 | 2022-01-11 | 英国神盾Tx股份有限公司 | 用于治疗或预防癌症和肿瘤的麦芽酚铁组合物 |
| CN109311837B (zh) | 2016-03-31 | 2022-09-30 | 英国神盾Tx股份有限公司 | 用于由氢氧化亚铁产生麦芽酚铁组合物的方法 |
| CN109790138B (zh) * | 2016-03-31 | 2023-08-18 | 英国神盾Tx股份有限公司 | 由配体修饰的和配体涂覆的氢氧化铁生产麦芽酚铁组合物的方法 |
| GB2553099A (en) * | 2016-08-19 | 2018-02-28 | Shield Tx Uk Ltd | Use |
| IT202100018578A1 (it) * | 2021-07-14 | 2023-01-14 | Indena Spa | Dispersione amorfa di maltolo ferrico e relativo processo di preparazione |
Family Cites Families (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IT1150213B (it) * | 1982-03-02 | 1986-12-10 | Italfarmaco Spa | Derivati di ferro biodisponibile esenti da gastrolesivita',procentimento di preparazione e relative composizioni farmaceutiche |
| SU1676626A1 (ru) * | 1989-05-17 | 1991-09-15 | Тюменский государственный медицинский институт | Способ лечени железодефицитных анемий |
| RO113611B1 (ro) * | 1990-08-03 | 1998-09-30 | Asta Pharma Ag | Preparate solide de ifosfamida, administrate oral si procedeu de obtinere |
| ES2230564T3 (es) | 1995-06-10 | 2005-05-01 | Vitra Pharmaceuticals Ltd. | Compuestos ferricos, composiciones, metodos de fabricacion de estos y sus utilizacioneds. |
| ID18663A (id) * | 1996-04-12 | 1998-04-30 | Novartis Ag | Komposisi farmasi berlapis enterik |
| NZ328751A (en) * | 1997-09-16 | 1999-01-28 | Bernard Charles Sherman | Solid medicament containing an anionic surfactant and cyclosporin |
| US7135196B2 (en) | 2000-09-19 | 2006-11-14 | Vitra Pharmaceuticals Limited | Iron compositions |
| US20050118291A1 (en) * | 2003-09-10 | 2005-06-02 | Mian-Ying Wang | Formulations and methods for treating breast cancer with Morinda citrifolia and methylsulfonymethane |
| MX2007013708A (es) * | 2005-05-03 | 2008-01-28 | Innozen Inc | Pelicula comestible para suministro transmucosa de complementos nutricionales. |
| EP1757299A1 (de) | 2005-08-25 | 2007-02-28 | Vifor (International) Ag | Eisen(III)-Komplexverbindungen zur Behandlung von Eisenmangel-Zuständen bei Patienten mit chronisch-entzündlicher Darmerkrankung |
| US20070111936A1 (en) * | 2005-11-15 | 2007-05-17 | Vladimir Pak | Complex of alpha-fetoprotein and inducers of apoptosis for the treatment of cancer |
| GB0808835D0 (en) * | 2008-05-15 | 2008-06-18 | Vitra Pharmaceuticals Ltd | Therapeutic compositions |
| GB201101370D0 (en) * | 2011-01-27 | 2011-03-09 | Iron Therapeutics Holdings Ag | Process |
| JP5856725B2 (ja) * | 2011-08-02 | 2016-02-10 | 和夫 酒井 | うつ病治療用または予防用医薬組成物 |
| CN106413706A (zh) | 2014-01-06 | 2017-02-15 | 铁治疗控股公司 | 三麦芽酚铁的剂量方案 |
| GB201418710D0 (en) | 2014-10-21 | 2014-12-03 | Iron Therapeutics Holdings Ag | Dosage regimen |
-
2015
- 2015-01-06 CN CN201580005412.7A patent/CN106413706A/zh active Pending
- 2015-01-06 AU AU2015204192A patent/AU2015204192B2/en active Active
- 2015-01-06 CA CA2934836A patent/CA2934836C/en active Active
- 2015-01-06 ES ES15701588T patent/ES2785391T3/es active Active
- 2015-01-06 EP EP15701588.4A patent/EP3091974B1/en active Active
- 2015-01-06 US US15/110,003 patent/US10179120B2/en active Active
- 2015-01-06 JP JP2016562082A patent/JP6556753B2/ja active Active
- 2015-01-06 CN CN202111268204.XA patent/CN114010629A/zh active Pending
- 2015-01-06 BR BR112016015766A patent/BR112016015766A2/pt not_active Application Discontinuation
- 2015-01-06 WO PCT/IB2015/050098 patent/WO2015101971A1/en not_active Ceased
- 2015-01-06 KR KR1020167021033A patent/KR102351422B1/ko active Active
- 2015-01-06 SI SI201531165T patent/SI3091974T1/sl unknown
-
2016
- 2016-07-05 IL IL246613A patent/IL246613B/en active IP Right Grant
-
2019
- 2019-04-05 JP JP2019072643A patent/JP2019131592A/ja not_active Withdrawn