JP2017501140A5 - - Google Patents
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- Publication number
- JP2017501140A5 JP2017501140A5 JP2016536248A JP2016536248A JP2017501140A5 JP 2017501140 A5 JP2017501140 A5 JP 2017501140A5 JP 2016536248 A JP2016536248 A JP 2016536248A JP 2016536248 A JP2016536248 A JP 2016536248A JP 2017501140 A5 JP2017501140 A5 JP 2017501140A5
- Authority
- JP
- Japan
- Prior art keywords
- cgvhd
- day
- cell transplantation
- ibrutinib
- medicament according
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Ceased
Links
- 239000003814 drug Substances 0.000 claims 16
- XYFPWWZEPKGCCK-GOSISDBHSA-N ibrutinib Chemical compound C1=2C(N)=NC=NC=2N([C@H]2CN(CCC2)C(=O)C=C)N=C1C(C=C1)=CC=C1OC1=CC=CC=C1 XYFPWWZEPKGCCK-GOSISDBHSA-N 0.000 claims 6
- 239000002177 L01XE27 - Ibrutinib Substances 0.000 claims 5
- 229960001507 ibrutinib Drugs 0.000 claims 5
- 238000002054 transplantation Methods 0.000 claims 4
- 210000004027 cell Anatomy 0.000 claims 3
- 206010006448 Bronchiolitis Diseases 0.000 claims 2
- 206010039710 Scleroderma Diseases 0.000 claims 2
- 230000000735 allogeneic effect Effects 0.000 claims 2
- 238000010322 bone marrow transplantation Methods 0.000 claims 2
- 238000011134 hematopoietic stem cell transplantation Methods 0.000 claims 2
- 230000000414 obstructive effect Effects 0.000 claims 2
- 208000011580 syndromic disease Diseases 0.000 claims 2
- 206010016654 Fibrosis Diseases 0.000 claims 1
- 208000017760 chronic graft versus host disease Diseases 0.000 claims 1
- 229940079593 drug Drugs 0.000 claims 1
- 230000004761 fibrosis Effects 0.000 claims 1
- 210000003958 hematopoietic stem cell Anatomy 0.000 claims 1
- 230000002685 pulmonary effect Effects 0.000 claims 1
- 150000003839 salts Chemical class 0.000 claims 1
- 229940124597 therapeutic agent Drugs 0.000 claims 1
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361910944P | 2013-12-02 | 2013-12-02 | |
| US61/910,944 | 2013-12-02 | ||
| US201461973178P | 2014-03-31 | 2014-03-31 | |
| US61/973,178 | 2014-03-31 | ||
| PCT/US2014/068177 WO2015084857A1 (en) | 2013-12-02 | 2014-12-02 | Methods of treating and preventing alloantibody driven chronic graft versus host disease |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020025682A Division JP2020105181A (ja) | 2013-12-02 | 2020-02-18 | 同種抗体により駆動される慢性移植片対宿主病を処置及び予防する方法 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2017501140A JP2017501140A (ja) | 2017-01-12 |
| JP2017501140A5 true JP2017501140A5 (enExample) | 2018-01-25 |
Family
ID=53270044
Family Applications (5)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016536248A Ceased JP2017501140A (ja) | 2013-12-02 | 2014-12-02 | 同種抗体により駆動される慢性移植片対宿主病を処置及び予防する方法 |
| JP2020025682A Ceased JP2020105181A (ja) | 2013-12-02 | 2020-02-18 | 同種抗体により駆動される慢性移植片対宿主病を処置及び予防する方法 |
| JP2022188655A Ceased JP2023029899A (ja) | 2013-12-02 | 2022-11-25 | 同種抗体により駆動される慢性移植片対宿主病を処置及び予防する方法 |
| JP2024010504A Ceased JP2024072291A (ja) | 2013-12-02 | 2024-01-26 | 同種抗体により駆動される慢性移植片対宿主病を処置及び予防する方法 |
| JP2025054634A Pending JP2025118595A (ja) | 2013-12-02 | 2025-03-27 | 同種抗体により駆動される慢性移植片対宿主病を処置及び予防する方法 |
Family Applications After (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020025682A Ceased JP2020105181A (ja) | 2013-12-02 | 2020-02-18 | 同種抗体により駆動される慢性移植片対宿主病を処置及び予防する方法 |
| JP2022188655A Ceased JP2023029899A (ja) | 2013-12-02 | 2022-11-25 | 同種抗体により駆動される慢性移植片対宿主病を処置及び予防する方法 |
| JP2024010504A Ceased JP2024072291A (ja) | 2013-12-02 | 2024-01-26 | 同種抗体により駆動される慢性移植片対宿主病を処置及び予防する方法 |
| JP2025054634A Pending JP2025118595A (ja) | 2013-12-02 | 2025-03-27 | 同種抗体により駆動される慢性移植片対宿主病を処置及び予防する方法 |
Country Status (14)
| Country | Link |
|---|---|
| US (5) | US20150157634A1 (enExample) |
| EP (1) | EP3076975A4 (enExample) |
| JP (5) | JP2017501140A (enExample) |
| KR (2) | KR20230104754A9 (enExample) |
| CN (2) | CN110478353B (enExample) |
| AU (4) | AU2014360758B2 (enExample) |
| BR (1) | BR112016012158A2 (enExample) |
| CA (2) | CA3210338A1 (enExample) |
| EA (1) | EA201691020A1 (enExample) |
| IL (4) | IL292522A (enExample) |
| MX (2) | MX389020B (enExample) |
| PH (2) | PH12020552048A1 (enExample) |
| TW (3) | TWI743019B (enExample) |
| WO (1) | WO2015084857A1 (enExample) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TWI662963B (zh) | 2012-06-04 | 2019-06-21 | 美商製藥有限責任公司 | 布魯頓氏酪胺酸激酶抑制劑之結晶形式 |
| EP3060218A4 (en) | 2013-10-25 | 2017-07-19 | Pharmacyclics LLC | Methods of treating and preventing graft versus host disease |
| AR102871A1 (es) | 2014-12-03 | 2017-03-29 | Pharmacyclics Llc | Métodos de tratamiento de fibrosis |
| EP3432879B1 (en) | 2016-03-22 | 2021-01-06 | Mayo Foundation for Medical Education and Research | Using fatty acid synthase inhibitors to treat fibrosis |
| WO2018002958A1 (en) * | 2016-06-30 | 2018-01-04 | Sun Pharma Advanced Research Company Limited | Novel hydrazide containing compounds as btk inhibitors |
| US20200054721A1 (en) * | 2016-10-21 | 2020-02-20 | Bruce R. Blazar | Materials and methods for treating or preventing graft-versus-host-disease |
| CZ2017787A3 (cs) | 2017-12-08 | 2019-06-19 | Zentiva, K.S. | Farmaceutické kompozice obsahující ibrutinib |
| WO2021038540A1 (en) | 2019-08-31 | 2021-03-04 | Sun Pharma Advanced Research Company Limited | Cycloalkylidene carboxylic acids and derivatives as btk inhibitors |
| US20240025990A1 (en) * | 2020-12-01 | 2024-01-25 | City Of Hope | Prevention and treatment of graft-versus-host disease (gvhd) |
| US20240139195A1 (en) * | 2021-01-30 | 2024-05-02 | Beigene Switzerland Gmbh | Methods of treating chronic active antibody-mediated rejection using btk inhibitors |
| US20240287781A1 (en) | 2023-02-28 | 2024-08-29 | Toto Ltd. | Wall-mounted flush toilet |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6326469B1 (en) | 1994-04-22 | 2001-12-04 | Sugen, Inc. | Megakaryocytic protein tyrosine kinases |
| US20060182723A1 (en) * | 2005-01-25 | 2006-08-17 | Spellberg Brad J | Methods for treating refractory infections in neutropenic individuals |
| KR20080098490A (ko) * | 2006-01-13 | 2008-11-10 | 파마시클릭스, 인코포레이티드 | 티로신 키나제 억제제 및 이의 용도 |
| SG166093A1 (en) * | 2006-09-22 | 2010-11-29 | Pharmacyclics Inc | Inhibitors of brutonæs tyrosine kinase |
| CA2730930C (en) * | 2008-07-16 | 2015-01-13 | Pharmacyclics, Inc. | Inhibitors of bruton's tyrosine kinase for the treatment of solid tumors |
| EP2424368B1 (en) * | 2009-04-29 | 2014-12-31 | Locus Pharmaceuticals, Inc. | Pyrrolotriazine compounds |
| CA2772199A1 (en) * | 2009-08-31 | 2011-03-03 | Amplimmune, Inc. | B7-h4 fusion proteins and methods of use thereof |
| NZ717373A (en) * | 2010-06-03 | 2017-11-24 | Pharmacyclics Llc | The use of inhibitors of bruton’s tyrosine kinase (btk) |
| US20120071497A1 (en) * | 2010-06-03 | 2012-03-22 | Pharmacyclics, Inc. | Methods of treating abc-dlbcl using inhibitors of bruton's tyrosine kinase |
| CA2841111A1 (en) * | 2011-07-08 | 2013-01-17 | Novartis Ag | Novel pyrrolo pyrimidine derivatives |
| US9522917B2 (en) * | 2012-04-11 | 2016-12-20 | Acerta Pharma B.V. | Bruton's tyrosine kinase inhibitors for hematopoietic mobilization |
| DK2854850T3 (da) * | 2012-05-25 | 2021-08-30 | Sloan Kettering Inst Cancer Res | Sammensætninger til behandling eller forebyggelse af strålingssygdom og gi-syndrom |
| WO2014127200A1 (en) * | 2013-02-15 | 2014-08-21 | Immunomedics, Inc. | Chimeric and humanized anti-histone antibodies |
| EP3060218A4 (en) * | 2013-10-25 | 2017-07-19 | Pharmacyclics LLC | Methods of treating and preventing graft versus host disease |
| IL315294A (en) * | 2015-03-03 | 2024-10-01 | Pharmacyclics Llc | Pharmaceutical formulations of bruton's tyrosine kinase inhibitor |
-
2014
- 2014-12-02 IL IL292522A patent/IL292522A/en unknown
- 2014-12-02 JP JP2016536248A patent/JP2017501140A/ja not_active Ceased
- 2014-12-02 CA CA3210338A patent/CA3210338A1/en active Pending
- 2014-12-02 AU AU2014360758A patent/AU2014360758B2/en active Active
- 2014-12-02 MX MX2016006955A patent/MX389020B/es unknown
- 2014-12-02 CA CA2932255A patent/CA2932255C/en active Active
- 2014-12-02 US US14/558,297 patent/US20150157634A1/en not_active Abandoned
- 2014-12-02 KR KR1020237021643A patent/KR20230104754A9/ko active Pending
- 2014-12-02 EP EP14867905.3A patent/EP3076975A4/en active Pending
- 2014-12-02 CN CN201910760757.3A patent/CN110478353B/zh active Active
- 2014-12-02 TW TW103141826A patent/TWI743019B/zh active
- 2014-12-02 PH PH1/2020/552048A patent/PH12020552048A1/en unknown
- 2014-12-02 BR BR112016012158A patent/BR112016012158A2/pt not_active Application Discontinuation
- 2014-12-02 WO PCT/US2014/068177 patent/WO2015084857A1/en not_active Ceased
- 2014-12-02 TW TW110135203A patent/TW202228700A/zh unknown
- 2014-12-02 KR KR1020167015178A patent/KR20160085817A/ko not_active Abandoned
- 2014-12-02 IL IL315228A patent/IL315228A/en unknown
- 2014-12-02 TW TW112113060A patent/TW202402295A/zh unknown
- 2014-12-02 CN CN201480074674.4A patent/CN105939717B/zh active Active
- 2014-12-02 EA EA201691020A patent/EA201691020A1/ru unknown
-
2016
- 2016-05-18 IL IL245715A patent/IL245715A0/en unknown
- 2016-05-27 MX MX2022000209A patent/MX2022000209A/es unknown
- 2016-06-02 PH PH12016501051A patent/PH12016501051A1/en unknown
-
2017
- 2017-12-01 US US15/829,087 patent/US20180078558A1/en not_active Abandoned
-
2020
- 2020-02-18 JP JP2020025682A patent/JP2020105181A/ja not_active Ceased
- 2020-06-26 AU AU2020204276A patent/AU2020204276A1/en not_active Abandoned
- 2020-07-29 US US16/942,151 patent/US20210177854A1/en not_active Abandoned
- 2020-08-12 IL IL276683A patent/IL276683A/en unknown
-
2022
- 2022-04-29 US US17/733,419 patent/US20230100137A1/en not_active Abandoned
- 2022-06-02 AU AU2022203810A patent/AU2022203810B2/en not_active Expired - Fee Related
- 2022-11-25 JP JP2022188655A patent/JP2023029899A/ja not_active Ceased
-
2023
- 2023-09-25 US US18/372,495 patent/US20240293409A1/en not_active Abandoned
-
2024
- 2024-01-26 JP JP2024010504A patent/JP2024072291A/ja not_active Ceased
- 2024-12-17 AU AU2024278490A patent/AU2024278490A1/en active Pending
-
2025
- 2025-03-27 JP JP2025054634A patent/JP2025118595A/ja active Pending
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