JP2017500856A5 - - Google Patents
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- JP2017500856A5 JP2017500856A5 JP2016538724A JP2016538724A JP2017500856A5 JP 2017500856 A5 JP2017500856 A5 JP 2017500856A5 JP 2016538724 A JP2016538724 A JP 2016538724A JP 2016538724 A JP2016538724 A JP 2016538724A JP 2017500856 A5 JP2017500856 A5 JP 2017500856A5
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Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2019168228A JP6985347B2 (ja) | 2013-12-12 | 2019-09-17 | トランスフェクションの強化のための膜透過性ペプチドならびにそれらを使用する組成物及び方法 |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361915429P | 2013-12-12 | 2013-12-12 | |
| US61/915,429 | 2013-12-12 | ||
| PCT/US2014/070176 WO2015089487A1 (en) | 2013-12-12 | 2014-12-12 | Membrane-penetrating peptides to enhance transfection and compositions and methods for using same |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019168228A Division JP6985347B2 (ja) | 2013-12-12 | 2019-09-17 | トランスフェクションの強化のための膜透過性ペプチドならびにそれらを使用する組成物及び方法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2017500856A JP2017500856A (ja) | 2017-01-12 |
| JP2017500856A5 true JP2017500856A5 (https=) | 2017-07-27 |
| JP6912887B2 JP6912887B2 (ja) | 2021-08-04 |
Family
ID=52273587
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016538724A Active JP6912887B2 (ja) | 2013-12-12 | 2014-12-12 | トランスフェクションの強化のための膜透過性ペプチドならびにそれらを使用する組成物及び方法 |
| JP2019168228A Active JP6985347B2 (ja) | 2013-12-12 | 2019-09-17 | トランスフェクションの強化のための膜透過性ペプチドならびにそれらを使用する組成物及び方法 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019168228A Active JP6985347B2 (ja) | 2013-12-12 | 2019-09-17 | トランスフェクションの強化のための膜透過性ペプチドならびにそれらを使用する組成物及び方法 |
Country Status (11)
| Country | Link |
|---|---|
| US (5) | US9856496B2 (https=) |
| EP (2) | EP3756690A3 (https=) |
| JP (2) | JP6912887B2 (https=) |
| KR (1) | KR102532559B1 (https=) |
| CN (2) | CN113105559A (https=) |
| AU (2) | AU2014361806B2 (https=) |
| BR (1) | BR112016013516A8 (https=) |
| CA (1) | CA2933561A1 (https=) |
| ES (1) | ES2808866T3 (https=) |
| SG (2) | SG10201811729PA (https=) |
| WO (1) | WO2015089487A1 (https=) |
Families Citing this family (40)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP6473079B2 (ja) * | 2012-05-02 | 2019-02-20 | ライフ テクノロジーズ コーポレーション | 高密度増殖およびトランスフェクション培地並びに発現増強物質の固有の組み合わせを用いる、哺乳類細胞における高収率一過性発現 |
| CN104583957B (zh) | 2012-06-15 | 2018-08-10 | 英特尔公司 | 具有无消歧乱序加载存储队列的重新排序的推测性指令序列 |
| EP2862062B1 (en) | 2012-06-15 | 2024-03-06 | Intel Corporation | A virtual load store queue having a dynamic dispatch window with a distributed structure |
| CN107748673B (zh) | 2012-06-15 | 2022-03-25 | 英特尔公司 | 包括虚拟加载存储队列的处理器和系统 |
| CN104823168B (zh) | 2012-06-15 | 2018-11-09 | 英特尔公司 | 用于实现从由加载存储重新排序和优化导致的推测性转发遗漏预测/错误中恢复的方法和系统 |
| TWI646422B (zh) | 2012-06-15 | 2019-01-01 | 英特爾股份有限公司 | 在處理器中之免消歧義失序載入/儲存佇列方法、微處理器、和非暫態性電腦可讀取儲存媒體 |
| EP2862069A4 (en) | 2012-06-15 | 2016-12-28 | Soft Machines Inc | INSTRUCTION DEFINITION FOR IMPLEMENTING LOAD MEMORY TRANSFER AND OPTIMIZATION |
| BR112016013516A8 (pt) | 2013-12-12 | 2020-05-19 | Life Technologies Corp | complexo de transfecção e seu uso para aumentar transporte de molécula de carga em células e para o tratamento de câncer e terapia gênica, bem como método in vitro para fornecer um poliânion a uma célula |
| CA2976376A1 (en) | 2015-02-13 | 2016-08-18 | Factor Bioscience Inc. | Nucleic acid products and methods of administration thereof |
| KR102669726B1 (ko) | 2015-07-13 | 2024-05-29 | 라이프 테크놀로지스 코포레이션 | Cho 세포에서의 개선된 일시적 단백질 발현을 위한 시스템 및 방법 |
| EP3423438A4 (en) * | 2016-03-01 | 2020-05-06 | Molecular Transfer, Inc. | PLANT VIRUS MOTOR PROTEINS AND METHOD FOR USE THEREOF |
| IL308824A (en) | 2016-08-17 | 2024-01-01 | Factor Bioscience Inc | Nucleic acid products and methods of administration thereof |
| JP7216641B2 (ja) * | 2016-09-30 | 2023-02-01 | ライフ テクノロジーズ コーポレイション | レンチウイルス製造用無血清懸濁系 |
| LT3675826T (lt) | 2017-08-31 | 2023-09-11 | Life Technologies Corporation | Katijoninės lipidų kompozicijos audiniams-specifiniam įterpimui |
| EP3684797A4 (en) | 2017-09-19 | 2021-07-07 | Cannametrix, LLC | CELL BASED ASSAY FOR QUANTIFYING THE POWER AND EFFECTIVENESS OF CANNABINOIDS AND / OR TERPENOIDS, AND RELATED METHODS OF USE |
| EP3765030A4 (en) * | 2018-03-16 | 2022-01-26 | Sarepta Therapeutics, Inc. | CHIMERIC PEPTIDES FOR ANTISENSE ADMINISTRATION |
| EP3833745A1 (en) | 2018-08-10 | 2021-06-16 | REGENXBIO Inc. | Scalable method for recombinant aav production |
| WO2020077178A1 (en) * | 2018-10-12 | 2020-04-16 | Ann & Robert H. Lurie Children's Hospital of Chicago | Plga-peg/pei nanoparticles and methods of use |
| GB201821269D0 (en) | 2018-12-28 | 2019-02-13 | Nippon Shinyaku Co Ltd | Myostatin signal inhibitor |
| CA3130108A1 (en) * | 2019-02-22 | 2020-08-27 | Life Technologies Corporation | Suspension system for adeno associated virus production |
| EP4005583A4 (en) * | 2019-04-01 | 2023-04-26 | Industry - University Cooperation Foundation Hanyang University | ANTI-CANCER AGAINST PEPTIDE-BASED CP2C |
| KR102261371B1 (ko) * | 2019-04-01 | 2021-06-08 | 한양대학교 산학협력단 | CP2c 표적 펩티드 기반 항암제 |
| KR20220046605A (ko) * | 2019-08-05 | 2022-04-14 | 뽈리쁠뤼스-트랑스펙씨옹 (쏘시에떼 아노님) | 양이온성 중합체에 그래프트된 헤테로사이클릭 화합물을 포함하는, 세포 내로 핵산 분자를 형질감염시키기 위한 조성물, 및 이의 적용 |
| KR102515464B1 (ko) * | 2020-04-29 | 2023-03-28 | 연세대학교 원주산학협력단 | 핵산 또는 유전자 형질감염 효율을 개선하는 세포독성 완화 막 투과 펩타이드 및 이의 용도 |
| US20260027179A1 (en) * | 2021-02-08 | 2026-01-29 | University Of British Columbia | Anti-synucleinopathy peptide and methods to treat neurodegenerative diseases |
| CN118475355A (zh) | 2021-07-08 | 2024-08-09 | 日本新药株式会社 | 肾毒性减轻剂 |
| TW202308664A (zh) | 2021-07-08 | 2023-03-01 | 日商日本新藥股份有限公司 | 腎毒性減輕劑 |
| CA3225573A1 (en) | 2021-07-08 | 2023-01-12 | Nippon Shinyaku Co., Ltd. | Precipitation suppressing agent |
| CN113563429A (zh) * | 2021-07-19 | 2021-10-29 | 天津大学 | 一种基于烷基化多肽的核酸递送系统及制备方法与应用 |
| WO2023014909A1 (en) * | 2021-08-04 | 2023-02-09 | AJK Biopharmaceutical, LLC | Amphiphilic peptides for nucleic acid and protein delivery |
| CN114106095B (zh) * | 2021-11-11 | 2023-06-09 | 华南理工大学 | 基于聚集诱导发光原理的细胞自噬检测分子探针及其制备方法和应用 |
| WO2023171804A1 (ja) | 2022-03-10 | 2023-09-14 | 日本新薬株式会社 | 抗ウイルスアンチセンスオリゴマー |
| KR102717793B1 (ko) * | 2022-05-26 | 2024-10-16 | 주식회사 바이오셀트란 | 신규한 미백 펩타이드 및 이를 함유하는 화장료 조성물 |
| CN119604312A (zh) | 2022-06-30 | 2025-03-11 | 生命技术公司 | 用于体内递送的脂质组合物 |
| GB202211597D0 (en) | 2022-08-09 | 2022-09-21 | Nchain Licensing Ag | Computer-implemented method and system |
| EP4642434A2 (en) | 2022-12-29 | 2025-11-05 | Life Technologies Corporation | Lipid compositions on the basis of ionizable lipids, use for delivery to immune cells |
| CN115947817B (zh) * | 2023-02-22 | 2024-07-02 | 甘肃中肽生物科技有限公司 | 一种肿瘤相关多肽及其制备方法和应用 |
| WO2026036019A1 (en) | 2024-08-09 | 2026-02-12 | Life Technologies Corporation | Method of producing a recombinant protein in hek-293 cells |
| WO2026076376A1 (en) | 2024-10-06 | 2026-04-09 | Mirus Bio Llc | Transfection reagent comprising cationic polymer and amphipathic compound |
| CN119775363A (zh) * | 2024-12-31 | 2025-04-08 | 澳门科技大学 | 一种多肽、免疫原、疫苗和用途 |
Family Cites Families (40)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4897355A (en) | 1985-01-07 | 1990-01-30 | Syntex (U.S.A.) Inc. | N[ω,(ω-1)-dialkyloxy]- and N-[ω,(ω-1)-dialkenyloxy]-alk-1-yl-N,N,N-tetrasubstituted ammonium lipids and uses therefor |
| FR2645866B1 (fr) | 1989-04-17 | 1991-07-05 | Centre Nat Rech Scient | Nouvelles lipopolyamines, leur preparation et leur emploi |
| US5279833A (en) | 1990-04-04 | 1994-01-18 | Yale University | Liposomal transfection of nucleic acids into animal cells |
| US5334761A (en) | 1992-08-28 | 1994-08-02 | Life Technologies, Inc. | Cationic lipids |
| US5316948A (en) | 1992-09-04 | 1994-05-31 | Life Technologies, Inc. | N4 -methyl-2'-deoxycytidine 5'-triphosphate and its use in polymerase-catalyzed nucleic acid syntheses |
| US5578475A (en) | 1993-07-12 | 1996-11-26 | Life Technologies, Inc. | Composition and methods for transfecting eukaryotic cells |
| US5674908A (en) | 1993-12-20 | 1997-10-07 | Life Technologies, Inc. | Highly packed polycationic ammonium, sulfonium and phosphonium lipids |
| US6075012A (en) | 1994-02-11 | 2000-06-13 | Life Technologies, Inc. | Reagents for intracellular delivery of macromolecules |
| US5627159A (en) | 1994-10-27 | 1997-05-06 | Life Technologies, Inc. | Enhancement of lipid cationic transfections in the presence of serum |
| EP0874910A4 (en) | 1995-06-07 | 1999-04-21 | Life Technologies Inc | ENHANCED CATIONIC LIPID TRANSFECTION BY PEPTIDES |
| US6051429A (en) * | 1995-06-07 | 2000-04-18 | Life Technologies, Inc. | Peptide-enhanced cationic lipid transfections |
| US5744335A (en) | 1995-09-19 | 1998-04-28 | Mirus Corporation | Process of transfecting a cell with a polynucleotide mixed with an amphipathic compound and a DNA-binding protein |
| SE9804614A0 (en) | 1998-07-06 | 2000-01-07 | A+ Science Invest Ab | New peptides and use thereof |
| NZ512244A (en) | 1998-11-12 | 2003-12-19 | Invitrogen Corp | Polycationic transfection reagents for introducing anions into a cell |
| US6664040B2 (en) | 2000-05-23 | 2003-12-16 | The Regents Of The University Of California | Compositions and methods for delivery of a molecule into a cell |
| JP5610659B2 (ja) | 2000-07-21 | 2014-10-22 | ルバンス セラピュティックス インク.Revance Therapeutics,Inc. | 多成分生物学的輸送システム |
| GB0103110D0 (en) | 2000-08-25 | 2001-03-28 | Aventis Pharma Inc | A membrane penetrating peptide encoded by a nuclear localization sequence from human period 1 |
| GB0106315D0 (en) * | 2001-03-14 | 2001-05-02 | Ich Productions Ltd | Transfection complexes |
| CA2513072A1 (en) | 2003-01-09 | 2004-07-29 | Invitrogen Corporation | Cellular delivery and activation polypeptide-nucleic acid complexes |
| WO2004105697A2 (en) | 2003-05-22 | 2004-12-09 | Molecular Transfer, Inc. | Novel lipids for transfection of nucleic acids |
| DE602004022056D1 (de) * | 2003-08-14 | 2009-08-27 | Diatos | Antibakterielle zusammensetzung, vor allem zur bekämpfung gramnegativer bakterien, umfassend ein peptid und ein vorteilhafterweise hydrophobes antibakterielles agens |
| US20050288246A1 (en) * | 2004-05-24 | 2005-12-29 | Iversen Patrick L | Peptide conjugated, inosine-substituted antisense oligomer compound and method |
| AU2006325030B2 (en) | 2005-12-16 | 2012-07-26 | Cellectis | Cell penetrating peptide conjugates for delivering nucleic acids into cells |
| ATE501169T1 (de) * | 2005-12-30 | 2011-03-15 | Evonik Roehm Gmbh | Lactoferrin-peptide, geeignet als in die zelle eindringende peptide |
| AU2007232206B2 (en) | 2006-03-30 | 2013-04-04 | Drais Pharmaceuticals, Inc. | Camptothecin-cell penetrating peptide conjugates and pharmaceutical compositions containing the same |
| NZ593080A (en) | 2006-05-05 | 2012-12-21 | Molecular Transfer Inc | Novel reagents for transfection of eukaryotic cells |
| JP5403681B2 (ja) | 2007-03-07 | 2014-01-29 | 独立行政法人国立国際医療研究センター | 新規核内移行ペプチド |
| EP2641911A3 (en) * | 2008-12-23 | 2014-01-01 | Vivoscript, Inc. | Compositions and methods for re-programming cells without genetic modification |
| US20110053829A1 (en) | 2009-09-03 | 2011-03-03 | Curevac Gmbh | Disulfide-linked polyethyleneglycol/peptide conjugates for the transfection of nucleic acids |
| WO2011127210A1 (en) | 2010-04-06 | 2011-10-13 | Massachusetts Institute Of Technology | Targeted delivery of nucleic acids |
| CN103097397B (zh) * | 2010-05-30 | 2015-11-25 | 多伦多大学管理委员会 | 作为抗癌化合物载体的线粒体穿透肽 |
| RU2556800C2 (ru) | 2010-06-14 | 2015-07-20 | Ф.Хоффманн-Ля Рош Аг | Пептиды, проникающие в клетки, и их применения |
| US9006417B2 (en) | 2010-06-30 | 2015-04-14 | Protiva Biotherapeutics, Inc. | Non-liposomal systems for nucleic acid delivery |
| CN103380113B (zh) | 2010-11-15 | 2018-03-30 | 生命科技公司 | 含胺的转染试剂及其制备和使用方法 |
| CN102153629B (zh) * | 2011-01-20 | 2013-07-24 | 华中科技大学 | 一种短肽及其应用 |
| US8853145B2 (en) * | 2011-11-14 | 2014-10-07 | Carlos Witte-Hoffmann | BLID; a novel protein domain for interaction with the Bcl-2 family of proteins |
| EP2825561A4 (en) * | 2012-03-15 | 2016-03-09 | Permeon Biolog Inc | CELL PENETRATING COMPOSITIONS FOR THE DISPOSAL OF INTRA-CELLULAR ANTIBODIES AND ANTIBODY-RELATED UNITS AND METHODS OF USE |
| BR112016013516A8 (pt) | 2013-12-12 | 2020-05-19 | Life Technologies Corp | complexo de transfecção e seu uso para aumentar transporte de molécula de carga em células e para o tratamento de câncer e terapia gênica, bem como método in vitro para fornecer um poliânion a uma célula |
| KR102476764B1 (ko) * | 2015-12-23 | 2022-12-14 | 에스케이하이닉스 주식회사 | 소자분리구조 및 그 제조 방법 |
| US9926825B2 (en) | 2016-04-19 | 2018-03-27 | GM Global Technology Operations LLC | Method and apparatus for exhaust purification for an internal combustion engine |
-
2014
- 2014-12-12 BR BR112016013516A patent/BR112016013516A8/pt not_active Application Discontinuation
- 2014-12-12 AU AU2014361806A patent/AU2014361806B2/en active Active
- 2014-12-12 CN CN202110386654.2A patent/CN113105559A/zh active Pending
- 2014-12-12 SG SG10201811729PA patent/SG10201811729PA/en unknown
- 2014-12-12 SG SG11201604697TA patent/SG11201604697TA/en unknown
- 2014-12-12 WO PCT/US2014/070176 patent/WO2015089487A1/en not_active Ceased
- 2014-12-12 CA CA2933561A patent/CA2933561A1/en active Pending
- 2014-12-12 US US14/569,583 patent/US9856496B2/en active Active
- 2014-12-12 ES ES14821440T patent/ES2808866T3/es active Active
- 2014-12-12 JP JP2016538724A patent/JP6912887B2/ja active Active
- 2014-12-12 EP EP20176262.2A patent/EP3756690A3/en active Pending
- 2014-12-12 KR KR1020167018604A patent/KR102532559B1/ko active Active
- 2014-12-12 EP EP14821440.6A patent/EP3079723B1/en active Active
- 2014-12-12 CN CN201480074785.5A patent/CN106456793B/zh active Active
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2017
- 2017-11-13 US US15/811,423 patent/US10760098B2/en active Active
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2019
- 2019-09-17 JP JP2019168228A patent/JP6985347B2/ja active Active
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2020
- 2020-03-19 AU AU2020202002A patent/AU2020202002B2/en active Active
- 2020-08-28 US US17/006,629 patent/US12152248B2/en active Active
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2024
- 2024-10-10 US US18/911,619 patent/US20250109412A1/en active Pending
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2025
- 2025-01-17 US US19/030,391 patent/US20250263751A1/en active Pending