JP2017155057A5 - - Google Patents
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- Publication number
- JP2017155057A5 JP2017155057A5 JP2017116440A JP2017116440A JP2017155057A5 JP 2017155057 A5 JP2017155057 A5 JP 2017155057A5 JP 2017116440 A JP2017116440 A JP 2017116440A JP 2017116440 A JP2017116440 A JP 2017116440A JP 2017155057 A5 JP2017155057 A5 JP 2017155057A5
- Authority
- JP
- Japan
- Prior art keywords
- parvovirus
- pharmaceutical composition
- composition according
- cancer
- bcl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 241000125945 Protoparvovirus Species 0.000 claims 9
- 239000008194 pharmaceutical composition Substances 0.000 claims 9
- 206010028980 Neoplasm Diseases 0.000 claims 5
- 239000012664 BCL-2-inhibitor Substances 0.000 claims 4
- 229940123711 Bcl2 inhibitor Drugs 0.000 claims 4
- 241000700605 Viruses Species 0.000 claims 2
- 208000003174 Brain Neoplasms Diseases 0.000 claims 1
- 206010006187 Breast cancer Diseases 0.000 claims 1
- 208000026310 Breast neoplasm Diseases 0.000 claims 1
- 206010008342 Cervix carcinoma Diseases 0.000 claims 1
- 206010009944 Colon cancer Diseases 0.000 claims 1
- 208000032612 Glial tumor Diseases 0.000 claims 1
- 201000010915 Glioblastoma multiforme Diseases 0.000 claims 1
- 206010018338 Glioma Diseases 0.000 claims 1
- 206010058467 Lung neoplasm malignant Diseases 0.000 claims 1
- 241000702321 Microvirus Species 0.000 claims 1
- 206010061902 Pancreatic neoplasm Diseases 0.000 claims 1
- 241000283984 Rodentia Species 0.000 claims 1
- 208000006105 Uterine Cervical Neoplasms Diseases 0.000 claims 1
- 201000011510 cancer Diseases 0.000 claims 1
- 201000010881 cervical cancer Diseases 0.000 claims 1
- 208000029742 colonic neoplasm Diseases 0.000 claims 1
- 230000003013 cytotoxicity Effects 0.000 claims 1
- 231100000135 cytotoxicity Toxicity 0.000 claims 1
- 208000005017 glioblastoma Diseases 0.000 claims 1
- 201000010536 head and neck cancer Diseases 0.000 claims 1
- 208000014829 head and neck neoplasm Diseases 0.000 claims 1
- 201000005202 lung cancer Diseases 0.000 claims 1
- 208000020816 lung neoplasm Diseases 0.000 claims 1
- 208000015486 malignant pancreatic neoplasm Diseases 0.000 claims 1
- 201000002528 pancreatic cancer Diseases 0.000 claims 1
- 208000008443 pancreatic carcinoma Diseases 0.000 claims 1
- 230000000306 recurrent effect Effects 0.000 claims 1
- 210000000130 stem cell Anatomy 0.000 claims 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP13003664.3 | 2013-07-22 | ||
| EP20130003664 EP2829284A1 (en) | 2013-07-22 | 2013-07-22 | Cancer therapy with a parvovirus combined with a Bcl-2 inhibitor |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016528375A Division JP6195988B2 (ja) | 2013-07-22 | 2014-07-22 | パルボウイルスにＢｃｌ−２阻害剤を併用する癌療法 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2017155057A JP2017155057A (ja) | 2017-09-07 |
| JP2017155057A5 true JP2017155057A5 (enExample) | 2017-11-16 |
Family
ID=48856486
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016528375A Active JP6195988B2 (ja) | 2013-07-22 | 2014-07-22 | パルボウイルスにＢｃｌ−２阻害剤を併用する癌療法 |
| JP2017116440A Pending JP2017155057A (ja) | 2013-07-22 | 2017-06-14 | パルボウイルスおよびＢｃｌ−２阻害剤を含有する医薬組成物 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016528375A Active JP6195988B2 (ja) | 2013-07-22 | 2014-07-22 | パルボウイルスにＢｃｌ−２阻害剤を併用する癌療法 |
Country Status (8)
| Country | Link |
|---|---|
| US (2) | US9889169B2 (enExample) |
| EP (2) | EP2829284A1 (enExample) |
| JP (2) | JP6195988B2 (enExample) |
| AU (1) | AU2014295442B2 (enExample) |
| CA (1) | CA2914420C (enExample) |
| DK (1) | DK3024491T3 (enExample) |
| ES (1) | ES2636768T3 (enExample) |
| WO (1) | WO2015010782A1 (enExample) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3069724A1 (en) * | 2015-03-19 | 2016-09-21 | Deutsches Krebsforschungszentrum | Lung cancer therapy with a rodent parvovirus |
| MX381890B (es) * | 2016-03-15 | 2025-03-13 | Oryzon Genomics Sa | Combinaciones de inhibidores de desmetilasa-1 especifica de lisina (lsd1) para uso en el tratamiento de tumores solidos |
| EP3429606A1 (en) * | 2016-03-17 | 2019-01-23 | Deutsches Krebsforschungszentrum | Lung cancer therapy with a parvovirus |
| EP3225253A1 (en) | 2016-04-01 | 2017-10-04 | Deutsches Krebsforschungszentrum Stiftung des Öffentlichen Rechts | Cancer therapy with an oncolytic virus combined with a checkpoint inhibitor |
| CN106177955B (zh) * | 2016-08-18 | 2018-03-16 | 广州威溶特医药科技有限公司 | Bcl‑xL抑制剂和溶瘤病毒在制备抗肿瘤药物中的应用 |
| WO2018213848A1 (en) * | 2017-05-19 | 2018-11-22 | The Regents Of The University Of California | Antibody chemically induced dimerizer (abcid) as molecular switches for regulating cellular therapies |
| EP3657172A1 (en) | 2018-11-22 | 2020-05-27 | Deutsches Krebsforschungszentrum, Stiftung des öffentlichen Rechts | Method for predicting the clinical response of oncolytic parvovirus h1 (h-1pv) treatment in a patient suspected of suffering from cancer by measuring the expression levels of laminins and/or galectins as biomarkers in a patient´s sample |
| US20240041833A1 (en) | 2020-12-21 | 2024-02-08 | Deutsches Krebsforschungszentrum Stiftung des öffentlichen Rechts | Pharmaceutical combination product comprising a protoparvovirus and an antiviral benzimidazole and uses thereof for treating cancer |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK2082745T3 (da) | 2007-12-28 | 2013-03-25 | Deutsches Krebsforsch | Kræftterapi med en parvovirus kombineret med kemoterapi |
| EP2366398A1 (en) | 2010-03-17 | 2011-09-21 | Deutsches Krebsforschungszentrum | Cancer therapy with a parvovirus combined with an HDAC inhibitor |
-
2013
- 2013-07-22 EP EP20130003664 patent/EP2829284A1/en not_active Withdrawn
-
2014
- 2014-07-22 EP EP14752272.6A patent/EP3024491B1/en active Active
- 2014-07-22 WO PCT/EP2014/002001 patent/WO2015010782A1/en not_active Ceased
- 2014-07-22 CA CA2914420A patent/CA2914420C/en active Active
- 2014-07-22 AU AU2014295442A patent/AU2014295442B2/en active Active
- 2014-07-22 JP JP2016528375A patent/JP6195988B2/ja active Active
- 2014-07-22 DK DK14752272.6T patent/DK3024491T3/en active
- 2014-07-22 ES ES14752272.6T patent/ES2636768T3/es active Active
-
2015
- 2015-12-07 US US14/960,608 patent/US9889169B2/en active Active
-
2017
- 2017-06-14 JP JP2017116440A patent/JP2017155057A/ja active Pending
- 2017-12-28 US US15/856,241 patent/US10406185B2/en active Active
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