JP2017137354A - 一日一回の投与のための吸収が制御された水溶性の薬学的に活性な有機化合物製剤 - Google Patents
一日一回の投与のための吸収が制御された水溶性の薬学的に活性な有機化合物製剤 Download PDFInfo
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- JP2017137354A JP2017137354A JP2017094634A JP2017094634A JP2017137354A JP 2017137354 A JP2017137354 A JP 2017137354A JP 2017094634 A JP2017094634 A JP 2017094634A JP 2017094634 A JP2017094634 A JP 2017094634A JP 2017137354 A JP2017137354 A JP 2017137354A
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- naproxen
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- BRABPYPSZVCCLR-UHFFFAOYSA-N methopromazine Chemical compound C1=CC=C2N(CCCN(C)C)C3=CC(OC)=CC=C3SC2=C1 BRABPYPSZVCCLR-UHFFFAOYSA-N 0.000 description 1
- 229950008620 methopromazine Drugs 0.000 description 1
- 229960000485 methotrexate Drugs 0.000 description 1
- 229940042053 methotrimeprazine Drugs 0.000 description 1
- VRQVVMDWGGWHTJ-CQSZACIVSA-N methotrimeprazine Chemical compound C1=CC=C2N(C[C@H](C)CN(C)C)C3=CC(OC)=CC=C3SC2=C1 VRQVVMDWGGWHTJ-CQSZACIVSA-N 0.000 description 1
- 229960005192 methoxamine Drugs 0.000 description 1
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- OEHAYUOVELTAPG-UHFFFAOYSA-N methoxyphenamine Chemical compound CNC(C)CC1=CC=CC=C1OC OEHAYUOVELTAPG-UHFFFAOYSA-N 0.000 description 1
- KFDDPVMIQMFHBI-JLIPXIIDSA-N methyl (1r,15s,17r,18r,19s,20s)-6,18-dimethoxy-17-[2-(4-methoxyphenoxy)acetyl]oxy-1,3,11,12,14,15,16,17,18,19,20,21-dodecahydroyohimban-19-carboxylate Chemical compound O([C@H]1[C@@H]([C@H]([C@H]2C[C@@H]3C4=C(C5=CC=C(OC)C=C5N4)CCN3C[C@H]2C1)C(=O)OC)OC)C(=O)COC1=CC=C(OC)C=C1 KFDDPVMIQMFHBI-JLIPXIIDSA-N 0.000 description 1
- FQUMWACBNIURCJ-RWZVGCGMSA-N methyl (1r,15s,17r,18r,19s,20s)-7-chloro-18-methoxy-17-(3,4,5-trimethoxybenzoyl)oxy-1,3,11,12,14,15,16,17,18,19,20,21-dodecahydroyohimban-19-carboxylate Chemical compound O([C@H]1[C@@H]([C@H]([C@H]2C[C@@H]3C4=C(C5=CC(Cl)=CC=C5N4)CCN3C[C@H]2C1)C(=O)OC)OC)C(=O)C1=CC(OC)=C(OC)C(OC)=C1 FQUMWACBNIURCJ-RWZVGCGMSA-N 0.000 description 1
- FNAMRDZHKYQEBA-YDQNNXAVSA-N methyl (2e,5z)-7-[(1r,2r,3r,5s)-2-[(e,3r)-4-(3-chlorophenoxy)-3-hydroxybut-1-enyl]-3,5-dihydroxycyclopentyl]hepta-2,5-dienoate Chemical compound COC(=O)\C=C\C\C=C/C[C@H]1[C@@H](O)C[C@@H](O)[C@@H]1\C=C\[C@@H](O)COC1=CC=CC(Cl)=C1 FNAMRDZHKYQEBA-YDQNNXAVSA-N 0.000 description 1
- ZZVPHCPLTZTOBC-BZXXIRPUSA-N methyl (e)-7-[(1r,2r,3r)-2-[(1e,5e)-6-(cyclopenten-1-yl)-4-hydroxy-4-methylhexa-1,5-dienyl]-3-hydroxy-5-oxocyclopentyl]hept-4-enoate Chemical compound O[C@@H]1CC(=O)[C@H](CC/C=C/CCC(=O)OC)[C@H]1\C=C\CC(C)(O)\C=C\C1=CCCC1 ZZVPHCPLTZTOBC-BZXXIRPUSA-N 0.000 description 1
- BDWABOZEWSSNDO-LRTQPEPLSA-N methyl (z)-7-[(1r,2r,3r)-2-[(e,3s,7r)-3,7-dihydroxyoct-1-enyl]-3-hydroxy-5-oxocyclopentyl]hept-5-enoate Chemical compound COC(=O)CCC\C=C/C[C@@H]1[C@@H](\C=C\[C@@H](O)CCC[C@@H](C)O)[C@H](O)CC1=O BDWABOZEWSSNDO-LRTQPEPLSA-N 0.000 description 1
- CIBHDGPIOICRGX-ZQCHCGQNSA-N methyl (z)-7-[(1r,2r,3r)-3-hydroxy-2-[(e)-4-hydroxy-4-methyloct-1-enyl]-5-oxocyclopentyl]hept-4-enoate Chemical compound CCCCC(C)(O)C\C=C\[C@H]1[C@H](O)CC(=O)[C@@H]1CC\C=C/CCC(=O)OC CIBHDGPIOICRGX-ZQCHCGQNSA-N 0.000 description 1
- YRSBGQIQVSGCJT-UHFFFAOYSA-N methyl 2-[3-[imidazol-1-yl(phenyl)methyl]phenyl]propanoate Chemical compound COC(=O)C(C)C1=CC=CC(C(C=2C=CC=CC=2)N2C=NC=C2)=C1 YRSBGQIQVSGCJT-UHFFFAOYSA-N 0.000 description 1
- QVFVAKQHELFATN-UHFFFAOYSA-N methyl 2-[[4-butyl-2-methyl-6-oxo-5-[[4-[2-(2h-tetrazol-5-yl)phenyl]phenyl]methyl]pyrimidin-1-yl]methyl]thiophene-3-carboxylate Chemical compound O=C1C(CC=2C=CC(=CC=2)C=2C(=CC=CC=2)C2=NNN=N2)=C(CCCC)N=C(C)N1CC=1SC=CC=1C(=O)OC QVFVAKQHELFATN-UHFFFAOYSA-N 0.000 description 1
- LYVGOAYMIAQLHI-UHFFFAOYSA-N methyl 2-butyl-1-[[2-fluoro-4-[2-(2h-tetrazol-5-yl)phenyl]phenyl]methyl]-6-oxopyridine-4-carboxylate Chemical compound CCCCC1=CC(C(=O)OC)=CC(=O)N1CC1=CC=C(C=2C(=CC=CC=2)C2=NNN=N2)C=C1F LYVGOAYMIAQLHI-UHFFFAOYSA-N 0.000 description 1
- VKQFCGNPDRICFG-UHFFFAOYSA-N methyl 2-methylpropyl 2,6-dimethyl-4-(2-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate Chemical compound COC(=O)C1=C(C)NC(C)=C(C(=O)OCC(C)C)C1C1=CC=CC=C1[N+]([O-])=O VKQFCGNPDRICFG-UHFFFAOYSA-N 0.000 description 1
- FWRHVNGHMPEEOH-MLWJPKLSSA-N methyl 3-[[(4r)-2-methyl-1,3-thiazolidine-4-carbonyl]amino]propanoate Chemical compound COC(=O)CCNC(=O)[C@@H]1CSC(C)N1 FWRHVNGHMPEEOH-MLWJPKLSSA-N 0.000 description 1
- VSIUFPQOEIKNCY-UHFFFAOYSA-N methyl 4-oxo-6,7-di(propan-2-yloxy)-1h-quinoline-3-carboxylate Chemical compound CC(C)OC1=C(OC(C)C)C=C2C(=O)C(C(=O)OC)=CNC2=C1 VSIUFPQOEIKNCY-UHFFFAOYSA-N 0.000 description 1
- QIGRQPVOWVHYBT-KABTVRTISA-N methyl 5-[(3as,5r,6r,6as)-5-hydroxy-6-[(e,3s)-3-hydroxyoct-1-enyl]-1,3a,4,5,6,6a-hexahydropentalen-2-yl]pentanoate Chemical compound C1=C(CCCCC(=O)OC)C[C@@H]2[C@@H](/C=C/[C@@H](O)CCCCC)[C@H](O)C[C@@H]21 QIGRQPVOWVHYBT-KABTVRTISA-N 0.000 description 1
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- OJLOPKGSLYJEMD-URPKTTJQSA-N methyl 7-[(1r,2r,3r)-3-hydroxy-2-[(1e)-4-hydroxy-4-methyloct-1-en-1-yl]-5-oxocyclopentyl]heptanoate Chemical compound CCCCC(C)(O)C\C=C\[C@H]1[C@H](O)CC(=O)[C@@H]1CCCCCCC(=O)OC OJLOPKGSLYJEMD-URPKTTJQSA-N 0.000 description 1
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Abstract
Description
本発明は、吸収が制御された薬学的製剤、および特に、錠剤、カプセル剤もしくは丸剤を嚥下するのが困難な者にとって受容可能な「軟らかい食品」とともに使用するのに適した粒状製剤を嚥下するのが容易な経口投与のための、および活性な化合物の時限式放出(timed release)が望ましい場合の経鼻胃管栄養チューブ(gastro−nasal feeding tube)もしくは他の「栄養チューブ」タイプ装置での薬学的に活性な化合物の投与のための、薬学的に活性な化合物の吸収が制御された形態に関する。
水溶性であって、消化管から容易に吸収される多くの薬物は、即放性(immediate release)投与形態の代わりに、1日1回の放出が制御された経口投与形態として、より有利に製剤化され得る。標準的な即放性製剤は、消化管において溶解されると直ぐに上記薬物を放出するように設計されているものであるので、放出が制御された投与形態への切り替えがなぜ有益であるのかには、少なくとも2つの理由がある。第1に、経口送達に特に関係して、摂取される薬物は、摂取後24時間以内に、ときおり、摂取後数時間以内に消化管を通過する。第2に、経口送達および非経口送達に関係して、大部分の薬物の半減期は、1日未満であり、通常は、数時間以下である。従って、薬物の標準的な即放性単一経口用量が24時間より長い間にわたって、大部分の場合には、数時間より長い間にわたって有効であることは非常に困難である。
Drug Discovery Volume 7, March 2008, 255−270)を参照のこと)。
一局面において、本開示は、粒状組成物を提供する。特定の実施形態において、上記粒状組成物は、(a)コアであって、上記コアは、薬学的に活性な物質を含み、上記薬学的に活性な物質は、1種以上の薬物結合ポリマーのセットとの相互作用を有する、コア;および(b)被覆であって、上記被覆は、膜形成ポリマーを含み、上記膜形成ポリマーは上記コアを取り囲んでおり、ここで上記薬学的に活性な物質は、薬学的に活性な化合物、上記薬学的に活性な化合物の薬学的に受容可能な塩もしくはそれらの組み合わせを含む、被覆、を含む。いくつかの実施形態において、上記粒状組成物は、(a)1種以上の薬物結合ポリマーのセットを含む、不活性コア;および(b)被覆であって、上記被覆は、膜形成ポリマーを含み、上記膜形成ポリマーは上記コアを取り囲んでいる、被覆、を含む。
(a)上記薬学的に活性な化学物質の合計のうちの15〜30%が、上記装置において0.5時間後の測定時に放出されている;
(b)上記薬学的に活性な化学物質の合計のうちの25〜60%が、上記装置において1時間後の測定時に放出されている;および
(c)上記薬学的に活性な化学物質の合計のうちの65%以上が、上記装置において4時間後の測定時に放出されている。
本明細書中に引用される全ての参考文献(刊行物、特許出願、および特許を含む)は、各参考文献が、個々にかつ具体的に参考として援用されると示され、その全体において示されたのと同程度まで、本明細書に参考として援用される。
に限定されない」を意味する)として解釈されるべきである。本明細書中の値の範囲の記載は、本明細書で別段示されなければ、その範囲内に入る各別個の値に個々に言及する略記法として働くと意図されるに過ぎず、各別個の値は、本明細書で個々に記載されるかのように、本明細書に援用される。本明細書に記載される全ての方法は、別段示されなければ、もしくは文脈が明らかに矛盾しなければ、任意の適した順序において行われ得る。任意のおよび全ての例の使用、または本明細書に提供される例示的語句(例えば、「例えば」「など」)は、本発明をよりよく明らかにすることが意図されるに過ぎず、別段特許請求されなければ、本発明の範囲に対する限定を提示しない。本明細書における語句はいずれも、何らかの特許請求されない要素が本発明の実施にとって必須であることを示すと解釈されるべきではない。
本発明の方法および組成物とともに使用され得る適切な生物学的に活性な物質は、任意のクラスの物質(麻酔薬、抗糖尿病薬、骨代謝調節薬(bone metabolic modulator)、心血管薬剤、中枢神経系抑制薬、胃腸薬、抗生物質、抗ウイルス剤、抗感染薬、抗菌薬、抗新生物薬、ホルモン、ステロイド薬、抗パーキンソン薬(antiparkensonian)、避妊薬、勃起不全因子(erectile dysfunction agents)、鎮痛薬、鎮痛剤(pain medications)、抗炎症薬、抗高脂血薬、診断薬、抗ヒスタミン薬、ペプチドおよびタンパク質、尿路因子(urinary tract agents)、精神治療薬、骨粗鬆症薬(osteoporosis medication)、免疫調節薬および抗喘息薬が挙げられる)のものであり得る。
ctisolide)、アクトジギン、アシクロビル、アダフェノキサート、アダメキシン、アダパレン、アダプロロール、アダタンセリン、アデフォビル、アデカラント(adekalant)、アデルミドロール、アデミトリオニン(ademitrionine)、アデノシン、アジベンダール(adibendal)、アジシリン、アジモロール、アジナゾラム、アジフェニン、アジテレン、アジトプリム、アドソピン、アドゼレシン、アドラフィニル、アドレナロン、アドロゴリド(adrogolide)、アファラニン、アフェレテカン(afeletecan)、アフロクアロン、アフォビルセン(afovirsen)、アフロロール、アガノジン、アグレプリストン、アゴメラチン、アクロミド、アラセプリル、アラホスファリン、アラゲブリウム、アラメシン(alamecin)、アラミフォビル(alamifovir)、アラニン、アラノシン、アラプロクラート、アラトロフロキサシン、アラザニントリクロフェネート(alazanine triclofenate)、アルバコナゾール、アルベンダゾール、アルブテロール、アルブトイン、アルクロフェナク、アルクロメタゾン、アルクロキサ、アルクロニウム、アルジオキサ、アルドステロン、アレムシナル、アレンドロン酸、アレンテモール、アレプリド、アレストラムスチン、アレタミン、アレキシジン、アレキシトール(alexitol)、アレキソマイシン(alexomycin)、アルファカルシドール、アルファデクス、アルフィダロン(alfidalone)、アルファプロストール、アルファトラジオール(alfatradiol)、α−キサロン(aldaxalone)、アルフェンタニル(alfentranil)、アルフゾシン(alfluzosin)、アルゲルドラート(algeldrate)、アルゲストン、アリベンドール、アリコナゾール、アリフェドリン、アリフラン(alifurane)、アリルセム(alilusem)、アリマドール、アリナスチン、アリニジン、アリパミンド(alipaminde)、アリスキレン、アリターム、アリトレチノイン、アリザプリド、アレトルフィン、アロバルビタール(allobarbitol)、アロカミド(allocamide)、アロクプレイド、アロメタジオン、アロプリノール、アリルエストレノール、アリルプロジン、アルメシリン、アルメストロン、アルミノプロフェン、アルミトリン、アルモカラント、アルモトリプタン、アルモキサトン、アルムルチド、アルネスピロン、アルニジタン、アロナシク酸(alonacic acid)、アロニミド、アロラセタム、アロセトロン、アロブジン、アロキシドン、アロキシプリン、アロキシスタチン、アロザホン、アルペルチン、アルファメプロジン、アルファメタドール、αメチルドパ、アルファプロジン、アルピデム、アルピロプリド、アルプラフェノン、アルプラゾラム、アルプレノロール、アルプレノキシム、アルプロスタジル、アルレスタチン、アルタンセリン、アルタピゾン、アルテコナゾール、アルチアジド、アルチニクリン、アルトクアリン(altoqualiine)、アルトレノガスト(altrenogast)、アルトレタミン、アルベメリン(alvemeline)、アルベリン、アルビモパン、アルボシジブ(alvocidib)、アマジノン、アマファロン(amafalone)、アマノジン、アマンタジン、アマントシリン、アンバムスチン、アンバシリド、アンバゾン、アンベノニウム、アンベノキサン、アルボマイシン(ambomycin)、アンブリセンタン、アンブロキソール、アンブルチシン、アムブカイン、アンブセタミド、アンブフィリン(ambuphylline)、アンブシド、アンブトニウム、アムシナファル、アムシナフィド、アムシノニド、アムジノシリン、アムドキソビル、アンブコート(ambucort)、アメダリン、アメロメタゾン、アメルトリド、アメルバント、アメセルギド、アメタントロン、アメトカイン、アメザピン(amezapine)、アメジニウム、アンフェナク、アンフェペントレクス、アンフェタミニル、アンフルチゾール、アンホネリン酸(amfonelic)、アミカルバリド、アミクローラル(amicloral)、アミシクリン、アニダンテル(anidantel)、アミダプソン、アミデフリン、アミフラミン、アミフロベリン、アミフロキサシン、アミホスチン、アミグルミド(amiglumide)、アミカシン、アミケリン、アミロリド、アミロキサート(amiloxate)、アミナクリン、アミンドカート、アミネプチン、アミノグルテチミド、アミノ馬尿酸、アミノレブリン酸、アミノメトラジン、アミノペンタミド、アミノフェナゾ
ン、アミノフィリン、アミノプロマジン、アミノプテリン、アミノピリン、アミノキノール、アミノキヌリド(aminoquinuride)、アミノレックス、アミノサリチル酸、アミノチアゾール、アミオダロン、アミペロン、アンフェナゾール(amphenazole)、アミピゾン、アミプロロース(amiprolose)、アミキンシン、アミソメトラジン、アミスルプリド(amisulprode)、アミテロール、アミチオゾン、アミチビル、アミトラズ、アミトリプチリン、アミトリプチリノキシド(amitriptyinoxide)、アミキセトリン、アンレキサノクス、アムリンチド、アムロジピン、アモカルジン、アモジアキン、アモラノン、アモナフィド、アモプロキサン、アモピロキン、アモロルフィン、アモスカナート、アモスラロール(amosulatol)、アモトサレン(amotosalen)、アモトリフェン、アモキサピン、アモキセカイン、アモキシシリン、アモキシドラミン、アンペロジド、アンフェクロラール(anphechloral)、アンフェニドン、アンフェタミン、アンホマイシン、アンホタリド、アンホテリシン、アンピシリン、アンピロキシカム、アンプレナビル、アンプロリウム、アンピリミン、アンピジン、アムキナート、アムルビシン、アムサクリン、アムトルメチン、アムスタリン(amustaline)、アミロバルビタール、アンゲストン(angestone)、アナグレリド、アナキンラ、アナリチド(anaritide)、アナストロゾール、アナチバント(anatibant)、アナキシロン、アナゾシン、アナゾレン、アンカロロール、アンシタビン、アンドラスト、アンドロステンジオール、アンドロステンジオン、アンデュラファンギン(andulafungin)、アネコルタブ、アネトールトリチオン、アンギオテンシンアミド、アンジドキサミン(andidoxamine)、アニデュラファンギン(anidulafungin)、アニラマート、アニレリジン、アニロパム、アニパミル、アニラセタム、アニロレート(anirolate)、アニサクリル、アニシンジオン、アニソピロール、アニソトロピン、アニスペリムス、アニトラザフェン、アンピルトリン、アンソキセチン(ansoxetine)、アンタフェニト、アンタゾリン、アンタゾニット、アンテルマイシン、アントラリン、アントラマイシン、アンチピリン、アントラフェニン、アパドリン、アパファント、アパルシリン、アパキサフィリン(apaxafylline)、アパジコン(apaziquone)、アパゾン、アピシクリン、アプリンドル、アポモルフィン、アポビンカミン、アプラクロニジン、アプラマイシン、アプレピタント、アプラカリム(aprakalim)、アプリンジン、アプリノカルセン(aprinocarsine)、アポフェン(apofene)、アプロスラート、アプタザピン、アプチガネル、アプトカイン、アラニジピン、アラノチン、アルバプロスチル(arbaprosil)、アルベカシン、アルブタミン、アルクロフェニン、アルダシン(ardacin)、アルデパリン、アレコリン、アルファラシン、アルフェンダザム、アルフォルモテロール(arformoterol)、アルガトロバン、アルギメスナ、アルギプレシン、アルギプレストシン、アルリドン(arlidone)、アリモクロモール、アリピプラゾール、アルモダフィニル、アルノロール(arnolol)、アロフィリン、アロチノロール(artinolol)、アルプリノシド、アルプロミジン、アルサニル酸、アルテフレン、アルテメーテル、アルテミシニン、アルテモチル、アルテニモール、アルテスナート、アルチカイン、アルチリド、アルンジン酸、アルゾキシフェン、アスコルビン酸、アルセナピン(arsenapine)、アセリピド、アシマドリン、アソバマスト、アソカイノール、アソプリスニル、アスパルテーム、アスパルトシン(aspartocin)、アスペルリン、アスピリン、アスポキシシリン、アステミゾール、アストロマイシン、アスラクリン、アタメスタン、アタプロスト、アタキマスト、アタザナビル、アテノロール、アテビルジン、アチベプロン、アチルモチン、アチパメゾール、アチプリモード、アチプロシン(atiprosin)、アチゾラム(atizoram)、アトリプロフェン、アトカルシトール、アトリド、アトモキセチン、アトルバスタチン、アトシバン、アトバクオン、アトラクリウム、アトラセンタン、アトラロイトン(atraleuton)、アトリムスチン、アトリノシトール、アトロメパン(atromepane)、アトロピン、アトロピンオキシド、オーラノフィン、アウロチオグルコース、アバナフィル、アバシ
ミベ、アビカトニン、
アバラマイシン(avalamycin)、アビプタジル、アビトリプタン、アビザホン、アボベンゾン、アボパルシン(azoparcin)、アボレリン、ピリジン、アキサモジド、アキシチロム、アキソマドール、アザボン、アザブペロン、アザシチジン、アザシチジン、アザクロルジン、アザコナゾール、アザコレステロール(azacosrterol)、アザシクロノール、アザフトジン、アザランスタット、アザロマイシン、アザロキサン、アザメチホス、アザメトニウム、アザムリン、アザナトル、アザニダゾール、アザペロン、アザペチン、アザキンゾール、アザリビン、アザロール、アザセリン、アザセトロン、アザスピリウム、アザステン、アザタジン、アザチオプリン、アゼライン酸、アゼラスチン、アゼルニジピン(azelinnidipine)、アゼペキソール、アゼピンドール、アゼテパ、アゼチレリン、アジダムフェニコール、アジドシリン、アジメキソン、アジミリド、アジンタミド、アジプラミド(azipramide)、アジスロマイシン、アズロシリン、アズロシリン、アゾリミン、アゾセミド、アゾマイシン(aztomycin)、アズトレオナム、アズモレン、バカンピシリン、バシトラシン、バクロフェン、バクメシリナム、バケプロフェン、バラグリタゾン、バラジポン、バロフロキサシン、バルサラジド、バマルゾール、バマキマスト、バンベルマイシン、バンブテロール、バメタン、バミフィリン、バミピン、バミラスチン、バミダゾール(bamidazole)、バノキサントロン、バキロプリム、バルベキサクロン、バルビタール、バリキシバト、バルマスチン、バルニジピン、バルカミド(barucamide)、バルシバン、バシファンギン(basifungin)、バタルブリン(batalbulin)、バタノプリド、バテブラスト、バテラピン、バチロール、バチマスタット、バトプロジン(batoprozine)、バキシトイジン(baxitoizine)、バゼドキシフェン、バジナプリン、ベカントン、ベカテカリン(becatecarin)、ベシパルシル、ベクラミド、ベクリコナゾール、ベクロブラート、ベクロメタゾン、ベクロチアミン、ベフェツピタント、ベフィペリド、ベフロキサトン、ベフノロール、ベフラリン、ベカナマイシン、ベラペリドン(belaperidone)、ベラリジン、ベルホスジル、ベロテカン、ベロキサミド、ベロキセピン、ベマリノン、ベメグリド、ベメセトロン、ベメチジド、ベミナフィル、ベミパリン(bemiparin)、ベメトラジン(bemetradine)、ベモラダン、ベモトリジノール、ベナクチジン、ベナフェントリン、ベナプリジン、ベナキシビン、ベナゼプリル、ベンシアノール、ベンシステイン、ベンクロニジン、ベンシクラン、ベンダカロール、ベンダムスチン、ベンダザック、ベンダゾール、ベンデリジン、ベンドロフルメチアジド(bendroflumethazide)、ベネタミンペニシリン、ベネキサート、ベンフルオレックス、ベンホスホルミン、ベンホチアミン、ベンフルオリジル(benfluorodil)、ベンヘパゾン、ベニジピン、ベンモキシン、ベノリジム、ベノリラート、ベノルテロン、ベノキシフォス(benoxifos)、ベノキサプロフェン、ベノキシナート、ベンペノリシン、ベンペリドール、ベンプロペリン、ベンリキサート、ベンサラン、ベンセラジド、ベンスルダズ酸、ベンタゼパム、ベンテマゾール、ベンチアミン、ベンチピミン、ベンチロミド、ベントクアタム(bentoquatam)、ベヌレスタット、ベンザルコニウム、ベンザロン、ベンズブロマロン、ベンゼストロール、ベンゼチジン、ベンゼトニウム、ベンゼチミド、ベンジロニウム、ベンジンドピリン、ベンジオダロン、ベンズマレセン、ベンズニダゾール、ベンゾバルビタール、ベンゾカイン、ベンゾクリジン、ベンゾクタミン、ベンゾデパ、ベンゾドデシニウム、ベンゾナタート、ベンゾピロニウム、ベンゾキノニウム、ベンゾトリプト、ベンゾキシキン、ベンゾキソニウム、ベンゾイルパス、ベンズフェタミン、ベンズピペリロン、ベンズピリニウム、ベンズクェルシン、ベンズキナミド、ベンズチアジド、ベンズトロピン、ベンジダミン、ベンジルヒドロクロロチアジド、ベンジルペニシリン、ベンジルスルファミド、ベパファント、ベペリジウム、ベフェニウム、ベピアスチン、ベプリジル、ベラクタント(beractant)、ベラプロスト、ベルベリン、ベレフリン、ベルゲニン、ベルラフェノン、ベルモプロフェン、ベルトサミル、ベルピパム、ベルバスタチン(bervastatin)、ベリスロマイシン(berythro
mycin)、ベシゴムシン、ベシピルジン、ベソンプロンジル(besonprodil)、ベスルパミド、ベスニド、β-カロテン、ベタセチルメタドール、ベタヒスチン、
ベタイン、ベタメプロジン、β‐メタドール、ベタメタゾン、ベタマイシン、ベタミプロン、β‐プロジン、ベタキソロール、ベタゾール、ベタナコール(bethanacol)、ベタニジン、ベチアチド、ベトキシカイン、ベバントロール、ベボニウム、ベキサロテン、ベキスロステリド(bexlosteride)、ベザフィブラート、ベズチラミド(beztiramide)、ビアラミコール、ビアペネム、ビベゾニウム(bibezonium)、ビブロカトール、ビカルタミド(bilcalutamide)、ビシファジン、ビコルジル(bicoldil)、ビクロフィブラート、ビクロチモール、ビコザマイシン、ビジマジウム、ビジソミド、ビエタミベリン、ビエタセルピン、ビフェメラン、ビフェプラミド、ビフェプロフェン、ビフェプルノクス、ビフルラノール、ビフォナゾール、ビラスチン、ビマカリム、ビマトプロスト、ビモクロモル、ビモシアモース、ビンダリット、ビネダリン、ビンフロキサシン(binfioxacin)、ビニフィブラート(binfibrate)、ビニラマイシン(biniramycin)、ビニゾラスト、ビノデノシン(binodenosine)、ビノスピロン、ビオアレトリン、ボチン(botin)、ビペナモール、ビペリデン、ビフェナミン、ビリコダル、ビリペロン、ビサコジル、ビサントレン、ビサラミル、ビスベンダゾール、ビスベンチアミン、ビスブチアミン、ビスデキリニウム(bisdequilinium)、ビスフェナゾン、ビスフェンチジン、ビスナフィド、ビソルビン(bisorbin)、ビスオクトリアゾール(bisoctriazole)、ビソプロロール、ビソルシク、ビソキサチン、ビスピリチオン(bispyrithione)、ビチオノール(bithonol)、ビチオノロキシド、ブチパゾン(butipazone)、ビトルテロール、ビトスカナート、ビバリルジン、ビゼレシン、ブレオマイシン、ブロナンセリン(blonanserine)、ブルエンソマイシン、ボフムスチン、ボランジオール、ボラステロン、ボラジン、ボルデノン、ボレノール、ボルマンタラート、ボメトロール、ボピンドロール、ボルナプリン、ボルナプロロール、ボレロン(borelone)、ボロカプタン(borocaptane)、ボルテゾミブ、ボセンタン、ボチアクリン、ボキシジン、ブラロバルビタール、ブラソフェンシン、ブラゼルゴリン、ブレホナロール、ブレマゾシン、ブレキナル、ブレタゼニル、ブレチリウム(bretyllium)、ブリフェンタニル、ブリモニジン、ブリナザプロン(brinazaprone)、ブリンドキシム、ブリンゾラミド、ブリブジン、ブロバクタム、ブロクレプリド、ブロクレスチン(brocrestine)、ブロクリナト、ブロジモプリム、ブロファロミン、ブロホキシン、ブロラコナゾール、ブロラムフェタミン、ブロマドリン、ブロマミド、ブロマゼパム、ブロムクロレノン、ブロメブル酸、ブロメルグリド、ブロメテナミン、ブロムフェナク、ブロムヘキセン(bromhexene)、ボミンジオン(bomindione)、ブロミソバルム、ブロモシクレン、ブロモクリプチン、ブロモジフェニルヒドラミン、ブロモフェンホス(bromofenfos)、ブロモホス、ブロモプリド、ブロモキサニド、ブロムペリドール、ブロムフェニラミン、ブロパレストロール、ブロペラモール、ブロピリミン、ブロキナルドール、ブロソタミンド(brosotaminde)、ブロスタリシン、ブロスキシミド、ブロチアニド、ブロチゾラム、ブロバネキシン、ブロビンカミン、ブロキサルジン、ブロキサテロール、ブロキシタルアミド(broxitalamide)、ブロクスウリジン、ブロキシキノリン、ブカミド(bucamide)、ブセチン、ブシクロビル、ブシラミン、ブシンドロール、ブクラデシン、ブクリジン、ブクロサミンド(buclosaminde)、ブクロクス酸、ブコルム、ブクリカイン、ブクロマロン、ブクモロール、ブデソニド、ブジピン、ブドチタン、ブドララジン、ブフェナドリン、ブフェニオド、ブフェトロール、ブフェキサマク、ブフェゾラク、ブフロメジル(bufromedil)、ブフォゲンチン(bufogentin)、ブホルミン、ブフロリン、ブフラロール、ブフィルリン(bufylline)、ブラキン、ブマジゾン、ブメカイン、ブメピジル、ブメタニド、ブメトリアゾール(bumetriazole)、ブナフチン、ブナミジン、ブナミオジル、ブナプロラスト、ブナゾシン、ブニトロロール、ブノロ
ール、ブパルバクオン、ブピコミド、ブピバカイン、ブプラノロール、ブプレノルフィン、ブプロピオン、ブキネリン(buquinerin)、ブキノラート、ブキテリン、ブラマート、ブロジリン、ブセレリン、ブスピロン、ブスルファン、ブトバルビタール、ブタカイン、ブタセチン、ブタクラモール、ブタジアザミド、ブタホスファン、ブタラミン、ブタルビタール、ブタンベン、ブタミラート、ブタミソール、ブタモキサン、ブタニリカイン、ブタンセリン、ブタントロン、ブタペラジン、ブタプロスト、ブタベリン、ブテドロネート(butedronate)、ビテナフィン(bytenafine)、ブテリジン、ブテナメート、ブチアジド、ブチブフェン、ブチフリン(butifrine)、ブチカシン、ブチルフェニン、ブチチゾシン、ブチノリン、ブチロシン、ブチキシラート、ブチキソコルト、ブトベンジン、ブトコナゾール、ブトクロロール、ブトクタミド、ブトフィオロール(butofiolol)、ブトナート、ブトパミン、ブトピプリン、ブトプロジン、ブトピルアンモニウム、ブトルファノール、ブトキサミン、ブトキシラート、ブトリプチリン、ブトロピウム、ブチルスコポラミン、ブチナミン、ブゼピド、カバスチン、カベルゴリン、カクチノマイシン(cactinomycin)、カドララジン、カドロフロキサシン(cadrofloxacin)、カファミノール(cafaminol)、カフェドリン、カフェイン、カルシフェジオール、カルシプロトリエン(calciprotriene)、カルシトリオール、カルコブトロール、カルダレト、カルジアミン(caldiamine)、カロキセチン酸、カルテリドール、クラウステロン(clausterone)、カマゼパム、カンベンダゾール、カマグリボース(camaglibose)、カミベリン、カンプトテシンおよびそのアナログ(例えば、9−アミノカンプトテシン、10−ヒドロキシカンプトテシン、7−エチル−10−ヒドロキシカンプトテシン、9−ニトロカンプトテシン、ならびに6員、7員および8員のラクトン環を有する全ての他のカンプトテシンアナログ)、カモナグレル、カモスタット、カミロフィン、カンビソール、カンデサルタン、カンジシジン、カンドクロニウム、カンドキサトリル、カンドキサトリラト、カネルチニブ、カンホスファミド(canfosfaminde)、カングレロール、カンナビノール、カンレノアート(canrenoate)、カンレノン、カペシタビン(capectitabine)、カポベナート、カポベン酸、カプラビリン、カプレオマイシン、カプロモレリン、カプロキサミン、カプサイシン、カプタミン、カプトジアム(captodiame)、カプトプリル、
カプリド、カラベルサット、カラセミド、カラフィバン、カラミフェン、カルバコール、カルバドクス、カルバマゼピン、カルベンテル(carbentel)、カルバゾン(carbasone)、カルバスピリン(carbaspirin)、カルバゼラン、カルバゾクロム、カルバゾシン、カルベニシリン(cabenicillin)、カルベノキソロン、カルベンジド、カルベタペンタン、カルベトシン、カルビドパ、カルビマゾール、カルビノキサミン、カルビフェン、カルボフェノチオン、カルボプラチン、カルボプロスト、カルボコン、カルブバーブ、カルブラゼパム、カルブタミド、カルブテロール、カルカイニウム、カレバスチン、カルフェンタニル、カルフィマート、カルグトシン、カリポリド、カリソプロドール、カルマンタジン、カルモフール、カルモテロール、カルムスチン、カミダゾール(camidazole)、カルニチン、カロカミド(carocamide)、カロベリン、カロキサゾン、カルペリジン、カルペリチド、カルペロン、カルフェナジン、カルピンドロール、カルピプラミン、カルプラジジル、カルプロフェン、カプロニウム(capronium)、カルサラム、カルサトリン、カルタステイン、カルタゾラート、カルテオロール、カルビシン、カルモナム、カルベジロール、カルボトロリン、カルゼレシン、カルゼニド、カサンスラノール、カソケファミンド(casokefaminde)、カスポフンギン(caspofungin)、カチン、カチノン、セバラセタム、セデフィンゴール、セファクロル、セファドロキシル、セファロニウム(cefalonium)、セファロラム、セファマンドール、セファパロール、セファトリアジン(cefatriazine)、セファザフルール、セファゼドン、セファゾリン、セフブペラゾン、セファネル(cefanel)、セフカペン、セフクリジン、セフダロキシム、セフジニル、セフジトレン、セフェドロロール、セフェムピドン(cefem
pidone)、セフェピム、セフェタメット、セフェテコール、セフェトリアオール(cefetriaole)、セフィブトリル(cefivtril)、セフィキシム、セフマチレン、セフメノキシム(cefmenoxine)、セフメピジウム、セフメタゾール、セミノクス(ceminox)、セフォジジム、セホニシド、セフォペラゾン、セホラニド、セフォセリス、セフォタキシム、セフォテタン、セフォチアム、セフォベシン、セホキサゾール、コホキシチン(cofoxitin)、セフォゾプラン、セフピミゾール、セフピラミド、セフポドキシム、セフプロジル、セフキノム、セフロチル、セフロキサジン、セフスロジン、セフスミド、セフタジジム、セフテラム、セフテゾール、セフチブテン、セフチオフル(ceftioflur)、セフチオレン、セフチオキシド、セフチゾキシム(ceftioxime)、セフトリアキソン、セフルアセタミン(cefuracetamime)、セフロキシム(cefuroxime)、セフゾナム、セレコキシブ、セルゴシビル、セリプロロール、セマドチン、セファセトリル、セファドリン(cephadrine)、セファレキシン、セファログリシン、セファロリジン、セファロチン、セファピリン、セファランチン、セフラジン、セリクラミン、セリバスタチン、セロナプリル、セルレチド、セタベン、セタルコニウム、セタモロール、セテフロキサシン、セテキソニウム、セスロマイシン、セチエジル、セチリスタット、セチリジン、セトシクリン、セトフェニコール(cetopheincol)、セトチアミン、セトキシム、セトラキサート、セトリモニウム、セチルピリジニウム、セビメリン、カウルモスルホン、ケノジオール、キノフォン(chinofon)、クロフィブラート(chlofibrate)、クロフェジアノール(chlophendianol)、クロラシジン、クロラロース、クロラムブシル、クロラミン−T、クロラムフェニコール、クロラザニル、クロルベノキサミン(chlorbenoxamine)、クロルベタミド、クロルシクリジン、クロルダントイン、クロルジアゼポキシド、クロルジモリン、クロルヘキシジン、クロリンダノール、クロリソンダミン、クロルマジオン(chloramadione)、クロルメロドリン、クロルメザノン、クロルミダゾール、クロルナファジン、クロロアゾジン、クロロプレドニソン、クロロプロカイン、クロロピラミン、クロロキン、クロロセルピジン、クロロセン、クロロチアジド、クロロトリアニセン、クロロキシン、クロロキシレノール、クロルフェネシン、クロルフェニラミン、クロルフェノクチウム、クロルフェノキサミン(chlorphenoxamine)、クロルフェンテルミン、クロルプロエタジン、クロルプログアニル、クロルプロマジン、クロルプロパミド、クロルプロチキセン、クロルピリホス、クロルテトラサイクリン、クロルタリドン、クロルテノキサジン、クロルゾキサゾン、コレカルシフェロール、コレステロール、コリンアルホスセラート、コリン、塩化第2クロム(chromic chloride)、クロモナール、シアドックス、シアフタラン(ciaftalan)、シアメキソン、シアネルゴリン、シアニダノール、シアノプラミン、シアピローム、シカプロスト、シカルペロン(cicarperone)、シクラクタート、シクラフリン、シクラジンドール、シクレソニド、シクレタニン(clcletanine)、シクリオメノール、シクロニカート、シクロニウム、シクロピロクス、シクロプラミン、シクロプロフェン、シクロプロロール、シクロシドミン、シクロチゾラム、シクロトロピウム、シクロキシル酸、シクロキソロン、シコルトニド、シドホビル、シドキセピン、シフェンリン、シホストジン、シグリタゾン、シヘプトラン、シラドパ、シランセトロン(cilansertron)、シラスタチン、シラザプリル、シレンギチド、シレキシン(cilexin)、シルニジピン、シロバミン、シロブラジン、シロフンギン、シロミラスト、シロスタミド、シロスタゾール、シルプレビル、シルタゾリン、シマテロール、シメモキシン、シメチジン、シメトロピウム、シミコキシブ、シモキサトン、シナカルセト、シナルカスト、シナメト酸、シナモロール、シナンセリン、シナプロキセン、シンコフェン、シネクロメン、シネパゼド、シネパジド、シンフェニン、シンフェノアク、シンフルミド(cinfiumide)、シンゲストール、シニタプリド、シンメタシン、シンナムアベリン、シンナムエドリン、シンナリジン、シンノフラジオン、シノクトラミド、シノジン、シノラゼパム、シノキドクス、シノキサシン、シノキサート、シノキソロン、シノキソパジド、シンペレン、シ
ンプラゾール、シンプロパジド、シンプロミド(cinpromide)、シンタゾン、シントリアミド、シヌペロン、シオテロネル、シパムフィリン、シペマスタット、シプラファミド、シプラリサント、シプラザホン、シプレファドール、シプロシノニド、シプロフィブラート、シプロフロキサシン、シプロキレン、シプロプリド、シプロクァゾン、シプレステン(ciprestene)、シラマドール、シラゾリン、シロレマイシン(cirolemycin)、シサプリド、シスアトラクリウム、シンコナゾール(cinconazole)、シスマジノン、シスプラチン、シスチネキシン、シタロプラム、シタテピン、シテナミド、シテナゾン、シチコリン、シチオロン、シゾリルチン、クラドリビン、クラミドクス酸、クラミカラント、クラモキシキン、クランフェヌル、クラノブチン、クランチフェン、クラリスロマイシン、クラブラナート(clavulanate)、クラゾラム、クラゾリミン、クラズリル、クレボプリド、クレファミド、クレマスチン、クレメプロール、クレミゾール、クレンブテロール、クレンピリン、クレンチアゼム、クレトキン、クレビジピン、クレブジン、クリブカイン、クリダフィジン、クリダナク、クリンジウム(clindium)、クリマゾラム、クリンバゾール、クリミクアリン、クリナフロキサシン、クリンダマイシン、クリノフィブラート、クリノラミド、クリンプロスト、クリキノール、クリオキサニド、クリプロフェン、クリロパミン、クロバザム、クロベノシド、クロベンゼパム、クロベノレクス(clobenorex)、クロベンズトロピン、クロベタゾール、クロベタゾン、クロブチノール、クロブザリト、クロカンファミド、クロカプラミン、クロシグアニル、クロシニジン、クロコルトロン、クロクマロール、クロダカイン、クロダノレン、クロダゾン、クロドキソポン、クロドロナート、クロファラビン、クロファジミン、クロフェナム酸、クロフェニクラン(clofeniclan)、クロフェネタミン、クロフェノキシド、クロフェビン(clofevine)、クロフェキサミン(clofexamine)、クロフェゾン、クロフィブラート、クロフィブル酸、クロフィブリド、クロフィリウム、クロフカルバ(clofucarba)、クロホクトール、クロホレクス、クロフラク、クロゲストン、クログアナミル、クロマクリン(clomacrin)、クロメゲストン、クロメタシン、クロメテロン、クロルメチアゾール、クロメトシリン(clometocillin)、クロミフェノキシド、クロミノレクス、クロミフェン、クロミプラミン、クロモサイクリン、クロモキシル、クロナゼパム、クロナゾリン、クロニジン、クロニタジン(clonitazine)、クロニキセリル、クロニキシン、クロパミド、クロペンチキソール、クロペラスチン、クロペリドン、クロピドグレル、クロピドール、クロピモジド、クロピパザン、クロピラク、クロポノン、クロプレンドール(cloprendol)、クロプロステノール、クロプロチアゾール、クロキナート、クロキノジン、クロラセタドール、クロラノロール、クロラゼパート、クロラゼプ酸、クロレタン(clorethane)、クロレキソロン(chlorexolone)、クロルフェンビノス(clorfenvinos)、クロルギリン、クロリクロメン、クロリダロール、クロルインダン酸、クロリンジオン、クロルメカイン、クロロペロン、クロロフェン、クロロクアロン、クロロテピン、クロルプレナリン、クロルスロン、クロルテルミン、クロサンテル、クロシラミン、クロステボール、クロチアピン、クロチキサミド、クロチアゼパム、クロチカソン、クロチオキソン、クロチキサミド、クロトリマゾール、クロボキサミン、クロキサセプリド、クロキサシリン、クロキサゾラム、クロキセストラジオール、クロキシマート、クロキソテストステロン、クロキシペンジル、クロキシキン、クロザピン、コバラミド(cobalamide)、コカイン、コデイン、コドキシム、コフィスタチン(cofistatin)、コガゾシン、コルヒチン、コレストロン、コルフェナマート、コルホルシン、コルホスセリル、コリメサイクリン(colimecycline)、コルテロール、コルラセタム、コネシン、コンガゾン(congazone)、コニバプタン、コノルフォン(conorphone)、コルメタソン、コルチコレリン、コルチゾン、コルチスゾール、コルチバゾール、コルトドキソン、コチニン、コトリプチリン、クマホス、クマゾリン、クメルマイシン、クメタロール、クレアチニン、クレアチノールホスファート、クレソタミド、クリダニモド、クリルバスチン(crilvastin)、クリスナトール、クロベネチン、ク
ロコナゾール、クロマカリム、クロミトリル、クロモグリカートリセチル、クロモリン、クロロム(crolom)、クロニジピン、クロプロパミド、クロタミトン、クロテタミド、クロトニアジド、クロトキシホス、クルホマート、クプリミキシン、クプロキソリン、シアセタシド、シアメマジン、シアノコバラミン(cyanocobalamine)、シクラシリン、シクラマート、シクラミン酸、シクランデラート、シクラルバマート、シクラゾシン、シクラゾドン、シクレキサノン、シクリンドール、シクリラミン、シクリジン、シクロバルビタール、シクロベンダゾール、シクロベンザプリン、シクロブト酸、シクロブチロール、シクロクマロール、シクロフェニル、シクログアニル、シクロヘキシミド、シクロメノール、シクロメチカイン、シクロペンタミン、シクロペンチアジド、シクロペントラート、シクロフェナジン、シクロホスファミド、シクロプレグノール、シクロピロニウム、シクロセリン、シクロチアジド(eyelothiazide)、シクロバロン、シクロチアミン(cyclotiamine)、シクリミン、シフルトリン、シハロトリン、シヘプタミド、シヘプトロピン、シナリン、シペナミン、シペルメトリン、シポトリン、シプラゼパム、シプレノルフィン、シプロデナート、シプロヘプタジン、シプロリドール、シプロキナート、シプロテロン、シプロキシミド、シロマジン、システアミン、システイン、シスチン、シタラビン、シチオラート(cythiolate)、ダペロチン、ダビガトラン、ダブザルグロン、ダカルバジン、ダセマジン、ダシノスタット、ダシステイン、ダコパファント、ダクチノマイシン、ダクロニウム、ダガパミル、ダグルリル(dagluril)、ダルババンシン、ダルブラミノール、ダルコチジン、ダレダリン、ダルホプリスチン、ダルテパリン、ダルトロバン、ダルバスタチン、ダメトララスト、ダモテピン、ダナゾール、ダニキドン、ダニトラセン(danittracen)、ダノフロキサシン、ダノステイン、ダントロン、ダントロレン、ダピプラゾール、ダピタント、ダピビリン、ダポキセチン、ダプソン、ダプトマイシン、ダルブフェロン、ダレンゼピン、ダルグリタゾン、ダリフェナシン、ダロジピン、ダルナビル、ダルセンタン、ダサンタフィル、ダテリプチウム(dateliptium)、ダウノルビシン、ダキサリプラム、ダザドロール、ダゼピニル、ダジダミン、ダズメグレル、ダゾリシン、ダゾプリド、ダゾキナスト、ダゾキシベン、デボキサメント(deboxament)、デブリソキン、デカメトニウム、デシメミド、デシタビン、デシトロピン、デクレンペロン、デクロプラミド、デクロキシジン、デコミノール、デコキナート、デクタフルル、デジトニウム、デフェラシロクス、デフェリプロン、デフェロキサミン、デフラザコルト、デホスファミン(defosfamine)、デホスリモド、デガレリックス、デヒドロ酢酸、デヒドロコール酸、デヒドロエメチン、デランテロン、デラプリル、デラビルジン、デルクアミン(delquamine)、デエルゴトリル(deergotrile)、デルファントリン、デルファプラジン、デルマジノン(selmadinone)、デルメタシン、デルモピノール(delmpinol)、デロラゼパム、デロキソロン、デルプロステナート、デルセミン、デムブレキシン、デメカリウム、デメクロサイクリン、デメコルシン、デメサイクリン、デメゲストン、デメルベリン、デメキシプチリン、デモコナゾール、デモキセパム、デモキシトシン、デナトニウム、デナベリン、デンブフィリン、デニプリド、デノフンギン(denofungin)、デノパミン、デノチビル、デンピダゾン、デヌホゾール、デンジモール、デペレスタット、デプラミン、デプレオチド、デプロドン、デプロスチル、デプトロピン、デクアリニウム、デラコキシブ、デラムシクラン、デリグリドール、デルパニカイン(derpanicaine)、デルサラジン、デサピジン、デスシクロビル、デスシノロン、デセルピジン、デシプラミン、デスラノシド(deeslanoside)、デスロラタジン(desloratidine)、デスロレリン、デスメニノール、デスメチルモラミド、デスモプレシン、デソクリプチン(desocriptine)、デソゲストレル、デソモルフィン(desmorphine)、デソニド、デスオキシメタゾン、デスオキシコルチコステロン、デスベンラファキシン、デタジミウム、デタノサール、デテレノール、デチレリックス、デチビシクロビル、デトロミジン(detromidine)、デトルビシン、デトロチロニン、デバパミル、デバゼピド、デキサメタゾン、デキサミソール、デキスブロムフェニラミン、デクスブデ
ソニド、デキスクロルフェニラミン、デキスクラモール、デキセカドトリル、デクスエファロキサン、デキセチミド、デキセトゾリン、デキスフェンフルラミン(dexfenfiuramine)、デキスホスホセリン、デキシブプロフェン、デキシマフェン、デキシンドプロフェン、デキシバカイン、デクスケトプロフェン、デクスロフェキシジン、デクスロキシグルミド、デクスメデトミジン、デクスメチルフェニダート、デキスナフェノドン(dexnafenodonee)、デキスニグルジピン、デクスノルゲストレル、デキソルマプラチン、デキソキサドロール、デクスパンテノール、デクスペメドラク、デクスプロプラノロール、デクスプロキシブテン、デキスラゾキサン、デキスセコベリン、デキスソタロール、デキスチリジン、デクスチオプロニン、デクストフィソパム、デキストロアンフェタミン、デキストロフェミン、デキストロメトルファン、デキストロモラミド、デキストロルファン、デキストロチロキシン、デクスセラピミル(dexcerapimil)、デザグアニン(sezaguanine)、デジナミド、デゾシン、ジアセレイン、ジアセタマート、ジアセトロール、ジアンフェネチド、ジアモカイン、ジアンプロミド、ジアンチアゾール(diamthiazole)、ジアパミド、ジアルバロン、ジアチモスルホン、ジアトリゾアート、ジアベリジン、ジアゼパム、ジアジクォン、ジアゾキシド、ジベカシン、ジベメチン、ジベンゼピン、ジベンゾチオフェン、ジブロムプロパミジン、ジブロムサラン(bibromsalan)、ジブロスピジウム、ジブカイン、ジブプロール、ジブピロン、ジブサドール、ジカルビン、ジカルフェン、ジクロラールフェナゾン、ジクロラミン、ジクロリソン、ジクロルメザノン、ジクロロフェン、ジクロロフェナルシン(dichlorphenarsine)、ジクロロキシレノール、ジクロルフェナミド、ジクロボス(dichlovos)、ジシフェロン、ジシレノン、ジクラズリル、ジクロフェナク、ジクロフェナミド、ジクロフェンシン、ジクロフトリウム(diclofutrime)、ジクロメチド、ジクロニキシン、ジクロラル尿素、ジクロキサシリン、ジクロリニウム(diclolinium)、ジクモール(dicummol)、ジシクロミン、ジダノシン、ジドロバルトラート、ジエルドリン、ジエネストロール、ジエノゲスト、ジエタジオン、ジエチルフタラート、ジエチルカルバマジン、ジエチルプロピオン(dietylpropion)、ジエチルスチルベストロール、ジエチルチアンブテン(dethylthambutene)、ジエチルトルアミド(dietyltoluamide)、ジエチフェン、ジフェバルバマート、ジフェメリン、ジフェメトレクス、ジフェナミゾール、ジフェンクロキサジン、ジフェノキシミド、ジフェノキシン、ジフェタルソン、ジフェテロール、ジフロモテカン、ジフロラゾン、ジフロキサシン、ジフルアニン、ジフルコルトロン、ジフルミドン、ジフルニサル、ジフルプレドナート、ジフタロン、ジギタリス、ジギトキシン、ジゴキシン、ジヘキシベリン、ジヒドララジン、ジヒドロコデイン、ジヒドロエルゴタミン、ジヒドロストレプトマイシン、ジヒドロタキステロール、ジイソブチルアミノベンゾイルオキシプロピルテオフィリン、ジイソプロミン、ジイソプロパノールアミン、ジイソプロピルアミン、ジラゼプ、ジレバロール、ジルメホン、ジロキサニド、ジルチアゼム、ジマベフィリン、ジマデクチン(dimadectin)、ジメカミン、ジメクロニウム(dimeclonium)、ジメクロト酸、ジメファダン、ジメフリン、ジメラジン、ジメンヒドリナート、ジメノキサドール、ジメフェプタノール、ジメプラノール、ジメプレグネン、ジメプロピオン(dimepropion)、ジメプロザン、ジメスナ、ジメソン、ジメタクリン、ジメタンフェタミン、ジメタジオン、ジメタザン、ジメチソキン、ジメチステロン、ジメトリジン、ジメトチジン(dimethothizine)、ジメトキサナート、ジメチルアミノエチルレセルピリネート、ジメチルタンブテン、ジメチルツボクラリニウム(dimethyltubocurarinium)、ジメチピリウム、ジメトフリン、ジメトリダゾール、ジミナゼン、ジミラセタム、ジモキサミン、ジモキサプロスト、ジモキシリン、ジムピラート、ジナリン、ジナザホン、ジニプロフィリン、ジニトルミド、ジノプロスト、ジノプロストン、ジンセド、ジオヒプル酸(diohippuric acid)、ジオスミン、ジオチロシン、ジオキサドロール、ジオキサマート、ジオキサフェチルブチラート、ジオキサチオン、ジオキセテドリン、ジオキシフェドリン、ジオキシベンゾン(dioxyben
azone)、ジオキシリン、ジペニン、ジペロドン、ジフェマニル、ジフェナジオン、ジフェナン、ジフェンクロキサジン、ジフェンヒドラミン、ジフェニドール、ジフェノキシラート、ジフェニルピペリジノメチルジオキソラン、ジフェニルピラリン、ジフェノキサジド(diphenoxazide)、ジピパノン、ジピプロベリン、ジピベフリン、ジプラフェノン、ジプレノルフィン、ジプロブチン、ジプロフェン、ジプログル酸、ジプロレアンドマイシン、ジプロフィリン(diprofylline)、ジプロクアロン、ジプロテベリン、ジプロトリゾアート、ジプロキサドール、ジピリダモール、ジピリチオン、ジピロセチル、ジピロン、ジクアホソル、ジリスロマイシン(dirithomycin)、ジルロタピド、ジセルモリド、ジスクオニウム、ジソブタミド、ジソフェニン(sidofenin)、ジソグルシド(sdisogluside)、ジソピラミド、ジソキサリル、ジスチグミン、ジスフェントン、ジスレルギン、ジスルファミド、ジスルフィラム(disulfuram)、ジスプラゾール(disuprazoole)、ジタゾール、ジテキレン、ジテルカリニウム、ジチアニン(dithiaanine)、ジチオケイド(ditiocade)、ジチオカルブ、ジチオムスタン(ditiomustane)、ジトラミド、ジトファール、ジバブテロール、ジバルプロエクス、ジバプロン、ジキサントゲン、ジザトリホン、ジゾシルピン(dizcilpine)、ドベシラート、ドブプリド、ドブタミド(dobutamide)、ドブタミン、ドカルパミン、ドセベノン、ドセタキセル、ドコナゾール、ドコネキセント、ドコサノール、ドクサート、ドデクロニウム、ドジシン、ドファミウム、ドフェキダル、ドフェチリド、ドラセトロン、ドリラセタム、ドマゾリン、ドミオドール、ドミフェン、ドミピゾン、ドミトロバン、ドモプレドナート、ドモキシン、ドンペリドン、ドネペジル、ドネチジン、ドニトリプタン、ドパマンチン、ドパミン、ドペキサミン、ドプロピジル、ドクァラスト、ドラマピモド(dorampimod)、ドラメクチン、ドラニダゾール、ドラスチン、ドレプチド(soreptidei)、ドレチネル、ドリペネム、ドルゾラミド、ドセルゴシド(dosergoside)、ドスマルファート、ドタリジン、ドテホニウム、ドチエピン、ドキサクリウム、ドキサプラム、ドキサプロスト、ドキサゾシン、ドキセファゼパム、ドキセニトイン、ドキセピン、ドキセルゴカルシフェロール(doxergocalciferol)、ドキシベタソール、ドキシフルリジン、ドキソフィリン、ドキソルビシン、ドクスピコミン、ドキシサイクリン、ドキシラミン、ドラフィアジン、ドラメジロール、ドラキノロール(draquinolo)、ドラジドクス、ドリベンダゾール(dribendazolew)、ドリミデン(drimidene)、ドロブリン、ドロシノニド、ドロクリジニウム、ドロフェニン、ドロロキシフェン、ドロメトリゾール、ドロモスタノロン、ドロナビノール、ドロネダロン(drinedarone)、ドロペンピン、ドロペリドール、ドロプレニラミン、ドロプロピジン、ドロスピレノン、ドロタベリン、ドロテバノール、ドロキサシン、
ドロキシカミド(droxicamide)、ドロキシカム、ドロキシドパ、ドロキシナビル(droxinavir)、ドロキシプロピン、ズアゾマイシン、デュロフィブラート、デュロキセチン、ズロザホン、ズモレリン(dumorelin)、ズメタシン(dumetacin)、デュオペロン、デュプラセタム、デュタステリド、ジクロニン、ジヒドロゲストロン(dyhydrogestrone)、ジマンチン、ジフィリン(dyphylline)、エバルゾタン、エバスチン、エベルコナゾール、エビラチド、エブロチジン、エブセレン、エカバピド、エカベト、エカドトリル、エカルシデン、エカムスル(ecamsule)、エカストロール、エセノフロキサシン(ecenofloxacin)、エコチオフェート(echothiophate)、エシプラミジル、エクラナミン、エクラゾラスト、エコムスチン、エコナゾール、エコピパム、エクラプロスト(ecraprost)、エクチル尿素、エダグリタゾン(edaglitazone)、エダラボン、エダトレキセート、エデルホシン、エデトール、エジホロン、エドゲストロン(edogestrone)、エドネンタン、エドテカリン、エドトレオチド、エドクスジン、エドラチド、エドロノカイン、エドロホニウム、エファプロキシラール、エファロキサン、エファビレンズ、エフェガトラン、エフェプリスチン(efepristin
)、エフェトゾール、エフレチリジン、エフロルニチン、エフロキサート、エフルチミブ、エルフマスト(elfumast)、エホニジピン、エフロトマイシン、エガノプロスト(eganoprost)、エグルメタッド、エグタズ酸、エクアレン(equalen)、エラクリダール、エラントリン、エランゼピン、エラロフィバン(elaarofiban)、エルバニジン、エルダシミブ、エレトリプタン、エルファゼパム、エルゴチピン(elgotipine)、エリナフィド、エリブロジル、エリサルタン、エラグ酸、エリプチニウム、エルムスチン、エルナジピン、エロピプラゾール、エルサミトルシン、エルタノロン、エルテナク、エルトプラジン、エルカイン、エルブシタビン、エルザゾナン、エルジベリン、エマカリム、エマプニル(emapunil)、エンブラミン、エンブサルタン、エンブトラミド、エメダスチン、エメプロニウム、エメチン、エミグリタート(emeglitate)、エミリウム、エミテフルル(emiteflur)、エミベリン(emiverine)、エモデプシド、エモパミル、エモルファゾン、エムトリシタビン、エミルカマート、エナドリン、エナラプリル、エナラプリラト、エナルキレン、エナザドレム、エンブクリラート、エンカミド(encamide)、エンシプラジン、エンクロミフェン、エンシプラート、エンジキサプリン、エンドミド、エンドララジン、エンドリソン、エネカジン、エネフェキシン、エネステボール、エンフェナム酸、エンフビルチド(enfluvirtide)、エングリタゾン、エニクロブラート、エニルコナゾール、エニロスピロン、エニルウラシル、エニポリド、エニソプロスト、エンロプラチン、エノシタビン、エノフェラスト、エノリカム、エノキサシン、エノキサマスト、エノキサパリン、エノキシモン、エノキソロン、エニピプラゾール(enipiprazole)、エンピロリン、エンプラゼピン、エンプロフィリン、エンプロマート、エンプロスチル、エンラマイシン、エンラセンタン、エンロフロキサシン、エンサシリン(ensacillin)、エンスリゾール(ensulizole)、エンタカポン、エンテカビル、エントスルホン(entsulfon)、エンビオマイシン、エンビラデン、エンビロキシム、エンザカメン(enzacamene)、アンザスタウリン(anzastaurin)、エパルレスタット、エパノロール、エペレゾリド、エペリゾン、エペルブジン、エフェドリン、エピカミド、エピシリン(epicillin)、エピクリプチン(epicriptine)、エピエストリオール、エピメストロール、エピナスチン、エピネフリン、エピネフェリル(epinepheryl)、エピプロピジン、エピリゾール、エピロプリム(apiroprim)、エピルビシン、エピテトラサイクリン、エピチアジド、エピチオスタノール、エプレレノン、エプリバセリン(elivanserin)、エポプロステノール、エポスタン、エプラジノン、エプリノメクチン、エプリステリド、エプロベミド、エプロサルタン、エプロバフェン、エプロキシンジン、エプロジノール、エプシプラネル(epsipranel)、エプタロプロスト(epaloprost)、エプタピロン、エプタプラチン、エプタスチグミン、エプタゾシン、エプチフィバチド、エキリン(equillin)、エルブロゾール、エルドステイン、エルゴカルシフェロール、エルゴノビン、エルゴタミン、エリトラン、エリゼピン、エルロチニブ、エルカミド(ercamide)、エルセンチリド、エルタペネム、エルチプロタフィブ、四硝酸エリスリチル(erythrity tetrnitrate)、エリスロマイシン、エサフロキサシン、エサプラゾール、エサテノロール(esatenolol)、エスシタロプラム、エスクラミン、エセリジン、エスフルルビプロフェン、エスケタミン、エスリカルバゼピン(escarbazepine)、エスモロール、エソメプラゾール、エソナリモッド、エソルビシン、エソキシブチニン(esoxybutynin)、エスパトロパート、エスプロキン、エスタゾラム、エストラジオール、エストラムスチン、エストラジノール(estrazinol)、エストリオール、エストロフラート、エストロン、エストロピパテンエスポン(estropipaten esupone)、エスゾピクロン(eszopclone)、エタベンザロン、エタセプリド、エタフェドリン、エタフェノン、エタロシブ、エタメストロール、エタミニル、エタミフィリン、エタモサイクリン、エタニダゾール、エタンテロール、エタクァロン、エタロテン、エタスリン、エタゼピン、エタゾラート、エテベネシド、エテロバルブ、エテルサラート
、エタクリジン、エタクリン酸、エタンブトール(ehtambutol)、エタミバン、エタムシラート、エタベリン、エテンザミド(ethenzameide)、エチアジド、エチナメート、エチニルエストラジオール、エチオナミド、エチステロン、エトヘプタジン、エトモキサン、エトナム、エトパバート、エトプロパジン、エトスクシミド、エトトイン、エトキサゼン、エトキサゾルトシド、エトキシゾラミド、エチベンズトロピン、エチルビスクマセタート、カルフルゼプ酸エチル、カルトリゾ酸エチル、エチルジブナート、ジラゼプ酸エチル、ロフラゼプ酸エチル、エチルエストレノール、エチルヒドロクプレイン、エチルメチルチアンブテン、エチルモルフィン、エチルノルエピネフリン(ethylnorepinepherine)、エチルスチルバミン(ethylstilbamine)、エチルネロン(ethylnerone)、エチルノジル(ethylnodil)、エチピコン、エチベンダゾール、エチクロプリド、エチシクリジン、エチドカイン、エチドロナート、エチドロン酸、エチフェルミン、エチフェニン、エチホキシン、エチランフェタミン、エチレフリン、エチレボドパ、エチニジン(etinidine)、エチピリウム、エチプレンドール(etiprendol)、エチプロストン、エチラセタム、エチロキサート、エチサゾール、エチソミシン、エチスレルギン、エチゾラム、エトカルリド、エトクリレン、エトドラク、エトドロキシジン、エトファミド、エトフェナマート、エトフェンプロクス、エトフィブラート、エトフェルミン(etofermin)、エトフラジン、エトフィリン、エトグルシド、エオロレクス(eorolex)、エトロチフェン、エトロキサミン、エトミダート、エトミドリン、エトモキシル、エトミタゼン(etomitazene)、エトノゲストレル、エトペリドン、エトポシド、エトプリンドール、エトプリン、エトリコキシブ、エトルフィン、エトサラミド、エトキサドロール、エトキセリジン、エトゾリン、エトラバミン、エトラビリン、エトレチナート、エトリシグアト、エトリプタミン、エチメマジン、オイカイン、オイカリプトール、オイゲノール、オイプロシン、エバンダミン、エベルニミシン、エベロリムス、エビクロミル、エキサラミド、エキサメタジム、エキサモレリン(examorelin)、エキサプロロール、エクサテカン、エキセメスタン、エキセパノール、エキシホン、エキシプロフェン(exiprofen)、エクシスリンド、エゼチミブ、エズロピタント、ファドルミジン、ファドロゾール、ファレカルシトリオール、ファリントロール、ファリパミル、ファルニダモール、ファムシクロビル、ファミラピニウム(famirapinium)、ファモチジン、ファモチン、ファンプリジン、ファンプロファゾン、ファンプロニル(fampronil)、ファナンセリン、ファナパネル、ファンドフロキサシン、ファンドセンタン、ファネチゾール、ファントファロン、ファントリドン、ファルグリタザル、ファシドトリル、ファシプロン、ファソラセタム、ファスジル(faudil)、ファザジニウム、ファザラビン、フェバンテル、フェバルバマート、フェブプロール、フェブベリン、フェブキソスタット、フェクレミン、フェクロブゾン、フェドトジン、フェドリラート、フェルバマート、フェルビナク、フェリピリン、フェロジピン、フェロプレンタン、フェリプレシン、フェモキセチン、フェナブテン、フェナセチノール、フェナクロン、フェナジアゾール、フェナフト酸、フェナラミド、フェマルコミン(femalcomine)、フェナミフリル、フェナモール、フェナペロン、フェンベンダゾール、フェンベニシリン、フェンブフェン、フェンブトレアザート(fenbutreazate)、フェンカンファミン、フェンシブチロール、フェンクレキソニウム、フェンクロフェナク(fleclofenac)、フェンクロニン、フェンクロラク、フェンクロズ酸、フェンジリン、フェンジゾアート、フェンドサール、フェネリトロール、フェネストレル、フェネタジン、フェネチリン、フェネトラジル、フェンフィウムゾール(fenfiumizole)、フェンフルラミン、フレンフルトリン(flenfluthrin)、フェンガビン、フェンハルマン、フェニミド、フェニオジウム、フェニペントール、フェニロフィブラート(fenirfibrate)、フェニソレクス、フェニトロチオン、フェンレウトン、フェンメトゾール、フェンメトラミド(fenmetraminde)、フェノバム、フェノシノール、フェノシチミン(fenocitimine)、フェノフィブラート、フェノールドパム、フェノプロフェン、フェノテロール、フェノエリン(
fenoerine)、フェノキサゾリン、フェノキセジル、フェノゾロン、フェンペンタジオール、フェンペラート、フェンプルパロン(fenprpalone)、フェンピプラミド、フェンピプラン、フェンピベリニウム、フェンプリナスト、フェンプロポレクス、フェンプロスタレン、フェンキアオン(fenquiaone)、フェンレチニド、フェンスピリド、フェンタニール、フェンチオン、フェンチアザク、フェンチクロル、フェンチコナゾール(fenticonazolem)、フェントニウム(fentonium)、フェンバレラート、フェニリポール、フェペントール酸、フェピトリゾール、フェプラジノール、フェプラゾン、フェプロミド、フェプロシドニン、フェルピホサート、フェソテロジン、フェトキシラート、フェキシカイン、フェキシニダゾール、フェキソフェナジン、フェザチオン、フェゾラミン、フィアシタビン、フィアルリジン、フィブラシリン、フィダレスタット、フィデキサバン、フィデュキソシン、フィゴピタント、フィラミナスト、フィレナドール、フィリピン、フィナフロキサシン、フィナステリド、フィンゴリモド、フィパメゾール、フィペキシド、フィプロニル、フィロコキシブ、
フラバミン、フラボド酸、フラボジロール、フラボキサート、フラザロン、フレカイニド(flecamide)、フレロブテロール、フレロキサシン、フレシノキサン、フレストロール、フレタゼパム、フレゼラスチン、フリバンセリン、フリンドカルネル、フロカルシトリオール(flocalcitriol)、フロクタフェニン、フロモキセフ、フロプロピオン(floptopione)、フロランチロン、フロルジピン、フロレジル、フロルフェニコール、フロリフェニン、フロサチジル、フロセキナン、フロスリド、フロトレニジン、フロベリン、フロキサシリン、フロキサクリン、フロクスウリジン、フルシジン(flucizine)、フルアラミン(flualamine)、フルアニソン、フルアザコルト、フルアズロン、フルバニラート、フルベンダゾール、フルベプリド、フルカルブリル、フルセトレクス、フルシンドール、フルシンプラジン(flucinprazine)、フルクロロニド、フルコナゾール、フルクリラート、フルシトシン、フルダラニン、フルダラビン、フルダゾニウム、フルデオキシグルコース、フルジアゼパム、フルドレクス、フルドキソポン、フルドロコルチゾン、フルフェナム酸、フルフェニサール、フルホサール、フルフィリン、フルゲストン(flugestone)、フルインダロール、フルインジオン、フルマゼニル、フリメシノール(flimecinol)、フルメドロキソン、フルメキン、フルメリドン、フルメタゾン、フルメチアゾール(flumethiazole)、フルメトラミド、フルメキサドール、フルメザピン、フルミノレクス、フルミゾール、フルモキソニド、フルナミン、フルナリジン、フルニダゾール、フルニソリド、フルニトラゼパム、フルニキシン、フルノプロスト、フルノキサプロフェン、フルオシノロン、フルオシノニド、フルオコルチンブチル、フルオコルトロン、フルオレセイン、フルオレソン、フルオロドパ、フルオロメトロン、フルオロサラン、フルオロウラシル、フルオトラセン、フルオキセチン、フルオキシメステロン、フルパロキサン、フルペンチキソール、フルペラミド、フルペルラピン、フルペロロン、フルフェナジン(flupheazine)、フルピマジン、フルピルチン、フルプラノン、フルプラジン、フルプレドニデン、フルプレドニソロン、フルプロフェン、フルプロフィリン、フルプロクァゾン、フルプロステノール、フルクァゾン、フルラドリン、フルランドレノリド、フルランテル、フルラゼパム、フルルビプロフェン、フルレトフェン、フルリスロマイシン、フルオロシタビン(fluorocitabine)、フルオロファミド(fluorofamide)、フルオロゲストン、フルソキソロール、フルスピペロン、フルスピリレン、フルタミド、フルタゾラム、フルテマゼパム、フルチアジン、フルチカゾン、フルチゼノール、フルトミダート、フルトニジン、フルトプラゼパム、フルトリマゾール、フルトロリン、フルトロピウム、フルバスタチン、フルボキサミン、フルジナミド、フルゾペリン、フォジピル、葉酸、ホメピゾール、ホミダシリン、ホミノベン、ホミビルセン、ホモカイン、ホナジン、ホンダパリヌクス、ホピルトリン、フォラサルタン、ホルフェニメックス、ホルメボロン、ホルメスタン、ホルメトレクス、ホルミニトラゾール、ホルモコルタール、フォルモテロール、ホロデシン、フォロパファント(foropafant)、ホスアンプレナビル、ホサリラート、ホサゼパム、ホセナジド、ホスフルコナ
ゾール、ホスホクレアチニン、ホスホマイシン、ホスホネト、ホスホサール、ホスフルクトース、ホシノプリル、ホシノプリラト、ホスメン酸、ホスミドマイシン、ホソパミン、ホスフェニトイン(fosphenyloin)、ホスピラート、ホスキドン、ホステジル、ホスルトリエシン(fosrtriecin)、ホスベセット(fosveset)、ホテムスチン、ホルトレナミン(fortrenamine)、ホジブジン、フラブプロフェン、フラダフィバン、フラケファミド、フラミセチン、フレンチゾール、フレセレスタット、フロネピジル、フロペネム、フロバトリプタン、フロキシプロスト、フタキシリド、フチバジド、フトルメタジン、フトルプロパジン、フブロゴニウム、フドステイン、フラデクチン(fuladectin)、フルベストラント、フマギリン、フモキシシリン、フンギマイシン(fungimycin)、フプラゾール、フラクリン酸、フラフィリン、フララジン、フラルタドン、フラプロフェン、フラザボール、フラゾリドン、フラゾリウム、フルビシリン(furbicillin)、フルクロプロフェン、フレグレラート、フレチジン、フルフェノレクス、フリダロン、フルメトキサドン、フルニジピン、フロブフェン、フロダゾール、フロフェナク、フロマジン、フロミン、フロセミド、フロスチルベストロール、フルサラン、フルスルチアミン、フルテレン(furtherene)、フルトレトニウム、フサフンギン、フシダート、フシジン酸、フズロシリン、ガバペンチン、ガバペキサート(gabapexate)、ガボキサドール、ガシクリジン、ガドベナート(gadobenate)、ガドブトロール、ガドコレクト酸(gadocolectic acid)、ガドジアミン(gadodiamine)、ガドホスベセット、ガドメリトール、ガドペナミド、ガドペンテタート、ガドテル酸、ガドテリドール、ガドベルセタミド、ガドキセタート(gadoxetate)、ガドキセト酸(gadoxeticaicid)、ガラムスチン、ガランタミン(galntamine)、ガラルビシン(galarubicin)、ガラソマイト(galasomite)、ガルダンセトロン、ガラミントリエチオジド、ガロパミル、ガロシタビン、ガロセミド、ガルチフェニン、ガンフェキシン、ガモレン酸、ガナキソロン(gamaxolone)、ガンシクロビル、ガネフロマイシン、ガングレフェン、ガンスチグミン、ガンタクリウム、ガントフィバン、ガピコミン、ガプロミジン、ガレノキサシン、ガチフロキサシン、ガベスチネル、ゲクロスポリン、ゲドカルニル、ゲフェルナート、ゲフィチニブ、ゲマゾシン、ゲムカベン、ゲムカジオール、ゲムシタビン、ゲメプロスト、ゲムフィブロジル(genfibtrozil)、ゲミフロキサシン、ゲモパトリラト、ゲンタマイシン、ゲペフリン、ゲピロン、ゲロキノール、ゲスタクロン、ゲスタジエノール、ゲストデン、ゲストノロン、ゲストリノン、ゲボトロリン、ギマテカン、ギメラシル、ギパルメン、ギラコダゾール、ギラクチド、ギリソパム、ギタロキシン、ギトホルマート、グラフェニン、グラスピモド、酢酸グラチラマー、グレマンセリン、グレンバスタチン、グリアミリド、グリボツヌリド(glibotnuride)、グリブチミン、グリカラミド、グリセタニド(glicetanide)、グリクラジド、グリコンダミン(glicondamine)、グリダザミド、グリフィウミド(glifiumide)、グリメピリド、グリパラミド、グリピジド、グリキドン、グリサムリド、グリセンチド、グリシンダミン(glisindamine)、グリソラミド、グリソキセピド、グロキサゾン、グロキシモナム(gloximonam)、グルカメタシン、グルコサミン、グルクロノラクトン(gluronolactone)、グルクロンアミド、グルニカート、グリブリド、グリブチアゾール、グルブゾール(glubuzole)、グリコピロラート(gycopyrrolate)、グリシルアミド(glycylamide)、グリヘキサミド、グリミジン、グリオクタミド、グリパラミド、グリピナミド、グリプロチアゾール(glyprothiazole)、グリソブゾール、ゴララチド、ゴセレリン、グラミシジン、グラニセトロン、グレパフロキサシン、グリセオフルビン、グアベンキサン、グアセチサール、グアフェカイノール、グアイアクタミン、グアヤパート、グアイエトリン、グアイフェネシン、グアイメサール、グアイステイン、グアイチリン、グアナベンズ、グアナクリン、グアナドレル、グアナゾジン、グアンクロフィン、グアンシジン、グアネチジン、グアンファシン、グアニソキン、グアノクロル、グアノクチン、グアノキサベンズ、グアノ
キサン、グアノキシフェン、グスペリムス、ハラゼパム、ハラゾン、ハルシノニド、ハレタゾール、ハロベタソール、ハロコルトロン、ハロファントリン、ハロフェナート、ハロフギノン、ハロメタゾン、ハロナミン、ハロペミド、ハロペニウム、ハロペリドール、ハロプレドン、ハロプロゲステロン、ハロプロジン、ハロキサゾラム、ハロキソン、ハロキノール(haloqionol)、ハマイシン(hamycin)、ヘダキニウム、ヘリオマイシン(heliomycin)、ヘプロニカート、ヘプタバルビタール、ヘプタベリン、ヘプトラミド、ヘプジシン、ヘロイン、ヘタシリン、ヘタフルル、ヘテロニウム、ヘキサクロロフェン、ヘキサシクロナート、ヘキサシプロン、ヘキサジリン、ヘキサフルオレニウム(hexafluorenium)、ヘキサメトニウム、ヘキサアミノレブリナート(hexaminolevulinate)、ヘキサプラドール、ヘキサプロフェン、ヘキサプロピマート、ヘキサソニウム、ヘキサゾール、ヘキセジン、ヘキセストロール、ヘキセチジン、ヘキソバルビタール、ヘキソベンジン、ヘキソシクリウム、ヘキソプレナリン、ヘキソピロニウム、ヘイルカイン(heylcaine)、ヒスタミン、ヒスタピロジン、ヒスチジン、ホマリラミン、ホマトロピン、ホミジウム、ホモクロルシクリジン、ホモフェナジン、ホモピプラモール、ホモサラート、ホムプレノルフィン、ホパンテン酸、ホキジル、ヒカントン、ヒドラカルバジン、ヒドララジン、ヒドラガフェン(hydragaphen)、ヒドロベンチジド、ヒドロクロロチアジド、ヒドロコドン、ヒドロコルチゾン、ヒドロフルメチアジド、ヒドロマジノン、ヒドロモルフィノール、ヒドロモルホン、ヒドロキノン、ヒドロキシインダサート(hydroxyindasate)、ヒドロキシインダソール(hydroxyindasol)、ヒドロキソコバラミン、ヒドロキシアンフェタミン、ヒドロキシクロロキン、ヒドロキシジオン、ヒドロキシペチジン、ヒドロキシフェナマート、ヒドロキシプロカイン、ヒドロキシプロゲステロン、酒石酸ヒドロキシピリジン、ヒドロキシステノゾール、ヒドロキシスチルバミジン、ヒドロキシテトラカイン、ヒドロキシジン、ヒメクロモン、ヒヨスチアミン、イバフロキサシン、イバンドロナート、イバゾシン、イボパミン、イブロリピム、イブロタミド、イブジラスト(ibudalast)、イブフェナク、イブプロフェン、イブプロキサム、イブタモレン、イブテロール、イブチリド、イブベリン、イカリジン、イカチバント、イクラプリム、イカゼパム(icazepam)、イコデュリニウム、イコフンギペン、イフォメタゾン(ifometasone)、イコペジル、イコサペント、イコスピラミド、イコチジン、イクロカプチド、イダルビシン、イダベリン、イダゾキサン、イデベノン、イデナスト、イドキシフェン、イドクスウリジン、イドラルフィジン、イドラマントン、イドラパリヌクス、イドラプリル、イドレムシナル(idremcinal)、イドロシリアミド(idrociliamide)、イドロノキシル、イドロプラノロール、イフェランセリン、イフェトロバン、イホスファミド、イホキセチン、イガニジピン、イグメシン、イグラチモド、イラプラゾール、イラトレオチド、イレプシミド、イリパルシル、イルモホシン、イロマスタット(iloomastat)、イロニダップ、イロペリドン、イマフェン、イマニキシル、イマチニブ、イマゾダン、イムカルボホス、イミクロパジン、イミダフェナシン、イミダプリル、イミダプリラト、イミドカルブ、イミドリン、イミド尿素、イミグリタザル、イミロキサン、イミノフェニミド、イミペネム、イミプラミン、イミプラミノキシド、イミキモド、イミレスタット、イミトロダスト、イモラミン、イモキシテロール、インパカルジン、インプリタピド、インプロミジン、
インプロスルファン、イムラセタム、イナミロン(inamirone)、イナペリゾン、インカドロン酸、インダカテロール、インダクリノン、インダルピン、インダナゾリン、インダニジン、インダノレクス、インダパミド、インダトラリン、インデカミド(indecamide)、インデロキサジン、インデノロール、インジブリン、インジゴチンジスルホネート、インジナビル、インジプロン、インジセトロン、インドブフェン、インドカート、インドシアニン・グリーン、インドラプリル、インドリダン、インドメタシン、インドパノロール、インドピン、インドプロフェン、インドラミン、インドレナート、インドキソール、インドリリン、イネカルシトール、イングリホリブ、イニカロン、酢酸イノクテロン(inocterone acetate)、イノガトラン、イノシン、イ
ノシトール、インプロクオン(improquoone)、イントプリシン、イントラゾール、イントリプチリン、イヌリン、イオベングアン、イオベンザム酸、イオビトリドール、イオブト酸、イカンリジン酸(icanlidic acid)、イオカルム酸、イオセタム酸、ヨーダミン、ヨージパミド、イオジキサノール、ヨードアンチピリン、ヨードコレステロール、ヨウ化ヒプル酸、ヨードキノール(iodoquinol)、ヨードチオウラシル、ヨードキサム酸(idoxamic acid)、イオフェタミン、イオフルパン、イオフラトール、イオグリク酸、イオグルコール、イオグルニド、イオグリカム酸、イオグラアミド(iogulaamide)、イオヘキシル(iohexyl)、イオリドン酸、イオリキサン酸、イオロプリド、イオマゼニール、イオメグラム酸、イオメプロール、ヨーメチン、イオメトパン、イオモリン酸、イオパミドール、イオパノ酸、イオペントール、イオフェンジラート、イオフェノキシ酸、イオプロミド、イオプロン酸、イオピドール、イオピドン、イオサルコール、イソフェナム酸(isofenamic
acid)、イオセル酸、イオシメノール、イオシミド、イオスラミド、イオスメト酸、イオタスル、イオテル酸(ioteric acid)、イオタラマート(iothalamate)、イオタラム酸、イオトラン酸、イオトリシド、イオトリゾ酸、イオトロラン、イオトロクス酸、ヨーチロシン、ヨーベソル(iovesol)、イオキサブロール酸、イオキサグル酸、イオキシラン、イオキシタラム酸、イオキソトリゾ酸、イオゾム酸、イパモレリン、イパジリド、イペノキサゾン、イペキシジン、イピダクリン、イポド酸塩、イプラグラチン(iprgratine)、イプラミジル、イプラトロピウム、イプラバカイン、イプラゾクロム、イプリフラボン、イプリンドール、イポシニジン(ipocinidine)、イプロクロジド、イプロクロドール(iprocrodol)、イプロフェニン、イプロヘプチン、イプロニアジド(iproniazide)、イプロニダゾール、イプロプラチン、イプロチアゼム、イプロキサミン、イプロジラミン、イプサラジド、イプサピロン、イキンダミン、イラルカスト(iralukast)、イラムパネル、イルベサルタン、イリンダロン、イリノテカン、イルロキサシン、イロフルベン、イロラプリド、イロキサナジン、イルソグラジン、イルテマゾール、イサリドール(isalidole)、イサルステイン、イサンファゾン、イサモルタン、イサモキソール、イサトリビン、イサキソニン、イスボグレル、イスブフィリン、イスパマイシン(ispamicin)、イソアミリニル(isoamilinile)、イソブロミンジオン、イソブカイン、イソブタンベン、イソカルボキサジド、イソコナゾール、イソクロミル、イソエタリン、イソフルプレドン(isofiupredone)、イソフルロファート(isofluorophate)、イソマゾール、イソメロール、イソメタミジウム、イソメサドン、イソメテプテン、イソモルパン、イソアミルアミン、イソニアジド、イソニキシン、イソプラゾール(isoprazole)、イソプレドニデン、イソプロフェン、イソプロパミド、イソプロピシリン(isopropicillin)、イソプロテレノール、イソソルビド(isosrbide)、イソスパグルム酸、イソスルファンブルー(isosulfan blue)、イソスルプリド、イソチペンジル、イソチキミド、イソトレチノイン、イソキサプロロール、イソキセパク、イソキシカム、イソクスプリン、イスラジピン、イスラパファント、イストラデフィリン(istrdefylline)、イタメリン、イタノキソン、イタセトロン、イタジグレル、イトプリド、イトラコナゾール、イトリグルミド、イトロカミド(itrocamide)、イトロシノニド(itrocinonide)、イツレリクス、イバブラジン(ivbradine)、イバリモド、イベルメクチン、イボクァリン、イキサベピロン、イゾンステリド、ジョサマイシン、カイニン酸、カラフンギン、カナマイシン、ケブゾン、ケラシアニン、ケタミン、ケタンセリン、ケタゾシン、ケタゾラム、ケトキサール、ケチプラミン、ケトベミドン、ケトカイン、ケトカイノール、ケトコナゾール、ケトプロフェン、ケトルファノール、ケトロラク、ケトチフェン、ケトトレキサート、ケリン、ケロシド、キタサマイシン、ラベタロール、ラブラジミル、ラケシン、ラシジピン、ラコサミド、ラクタルファート、ラクチロール(lactilol)、ラクツロース、ラジルビシン、ラドスチギル、ラフルニムス、ラクチジン(laftiine)、ライドロマイシンプロピオナート、ラミ
フィバン、ラミブジン、ラモトリギン、ラミチジン(lamitidine)、ラナトシド、ランジオロール、ラネピタント、ラニセミン、ラニキダル、ラノコナゾール、ランペリソン、ランプロストン、ランレオチド、ランソプラゾール、ラパチニブ、ラピステリド、ラプラフィリン(laprafylline)、ラピリウム、ラキニモド、ラサロシド、ラシナビル、ラソホキシフェン、ラタノプロスト、ラウデキシウム、ラウルセチウム、ラウロカプラム、ラウログアジン、ラウロリニウム、ラウリルイソキノリニウム、ラボルチジン、ラザベミド、レシミビド、レダゼロール、レドキサントロン、レフェタミン、レフルノミド、レフラダフィバン、レイオピロール、レミドスル、レミジピン(lemidipine)、レミノプラゾール、レモキシノール(lemoxinol)、レムテポルフィン、レナリドミド(lanalidomine)、レナンピシリン、レナペネム、レニキシン(leniquisin)、ロイペロン(leuperone)、レプタクリン、レルカニジピン、レルゴトリル、レリセトロン、レソプチロン(lesoptiron)、レストールチニブ、レテプリニム、レテプリニム、レチミド、レトステイン、レトラズリル、レトロゾール、ロイシノカイン、ロイコシアニドール、ロイコボリン、ロイルビシン、レバルブテロール、レバロルファン、レバンフェタミン、レバミソール、レブクロマカリム、レブシクロセリン、レブドブタミン、レベモアミル(levemoamil)、レベチラセタム、レビソプレナリン、レブロフェキシジン、レブメタンフェタミン、レボベタキソロール、レボブノロール、レボブピバカイン(levobupiacaine)、レボカバスチン、レボカルニチン(levocamitine)、レボドパ、レボドロプロピジン、レボファセトペラン、レボフェンフルラミン、レボフロキサシン、レボフルラルタドン(levofluraltadone)、レボロイコボリン、レボメノール、レボメプロマジン、レボメサドン、レボメタジルアセタート、レボメソルファン、レボメチオメプラジン、レボモプロロール、レボモラミド、レボナントラドール、レボノルデフリン、レボノルゲストレル、レボフェナシルモルファン、レボプロポキシフェン、レボプロピルシリン(levopropylcilline)、レボプロピルヘキセドリン(levopropuylhexedrine)、レボプロチリン、レボリン、レボルメロキシフェン、レボルファノール、レボサルブタモール、レボセモチアジル、レボシメンダン、レボスルピリド、レボチロキシン、レボトフィソパム、レボキサドロール、レキシパファント、レキシスロマイシン、レキソフェナク、リアロゾール、リベシリド、リベンザプリル、リカルバゼピン、リコフェロン、リコスチネル、リダドロン酸、リダミン(lidamine)、リダンセリン、リドカイン、リドフェリン(lidoferin)、リドレスタット、リファリジン(lifariaine)、リフィブラート、リフィブロール、リロプリストン、リマプロスト、リマゾシク酸(limazocic acid)、リナロテン、リンコマイシン、リンダン、リネタスチン、リネゾリド、リノグリリド、リノピルジン、リノトロバン、リシニドミン(lisinidomine)、リンチトリプト、リントプリド、リオチロニン、リポ酸、リラグルチド、リラナフタート、リレキニル、リレキサプリド、リリミラスト、リロルジン、リサジマート、リシノプリル、リソフィリン、リスリド、リトメグロビル、リトキセチン、リトラセン、リビドマイシン、リキサジノン、リキシバプタン、ロバプラチン(lobapolatin)、ロベリン、ロベンダゾール、ロベンザリット、ロブカビル、ロブプロフェン、ロシコルトロン(locicortolone)、ロダキサプリン、ロダゼカル、ロデラベン、ロデノシン、ロジニキシル(Iodiuixil)、ロジペロン、ロドキサミド、ロフェミゾール、ロフェンダザム、ロフェンタニル、ロフェプラミン、ロフェキシジン、ロフルカルバン、ロンバゾール、ロメフロキサシン(lomefioxacin)、ロメグアリブ(lomeguarib)、ロメリジン、ロメトラリン、ロメトレキソール、ロメバクトン、ロミフィリン、ロモフンギン、ロムスチン、ロナファルニブ、ロナパレン、ロナプロフェン、ロナゾラク、ロニダミン、ロペラミド、ロピナビル、ロピラゼパム、ロポブタン、ロプラゾラム、ロラカルベフ、ロラジミン、ロラプリド、ロラゼパム、ロルバマート、ロルカミド(lorcamide)、ロルシナドール、ロレクレゾール、ロルグルミド、ロルメタゼパム、ロルノキシカム、ロピプラゾール(lopiprazole)、ロルタラミン、ロルザホン
、ロサルタン、ロシガモン、ロシンドール、ロスミプロフェン、ロソキサントロン、ロスラジン、ロテプレドノール、ロトラフィバン、ロトリフェン、ロツカイン、ロバスタチン、ロビリド、ロキサナスト、ロキサピン、ロキシグルミド、ロキソプロフェン、ロキソリビン、ロジル尿素、ルバゾドン、ルベルゾール、ルビプロストン、ルカントン、ルカルタミド、ルイマイシン(lucimycin)、ルフェヌロン、ルフィロニル、ルフラドム、ルリコナゾール、ルミラコキシブ、ルピチジン、ルプロスチオール、ルラシドン、ルロセトロン、ルルトテカン(lurototecan)、ルザペリドン、ルキサベンダゾール、リジマイシン(lydimycin)、リメサイクリン、リネストレノール、リプレッシン(lypressin)、マブプロフェン、マブテロール、マヅラミシン、マフェニド、マホプラジン、マホスファミド、マラチオン、マレイルスルファチアゾール、マロチラート、マンガホジピル、マニジピン、マニファキシン、マンノムスチン、マノゾジル、マンタベグロン、マピナスチン(mapinastine)、マプロチリン、マラビロク、マルボフロキサシン、マリバビル、マリドマイシン、マリマスタット、マリプチリン、マロピタント、マロキセピン、マソプロコール、マキサカルシトール、メイタンシン、マザペルチン、マザチコール、マジンドール、マジプレドン、マゾカリム、メバナジン、メベンダゾール、メンベノシド(menbenoside)、メベベリン、メベゾニウム、メブヒドロリン、メビキン、メボラジン、メブロフェニン、メブタマート、メブチジド、メカミルアミン、メカルビナート、メセトロニウム、メシアダニル(meciadanil)、メシナロン、メクリネルタント、メクリジン、メクロサイクリン、
メクロフェナム酸(meclofenamaic acid)、メクロフェノキサート、メクロナゼパム、メクロカロン、メクロリソンジブチラート、メクロキサミン、メコバラミン、メダゼパム、メダゾミド、メデトミジン、メジバジン、メジホキサミン、メドリノン、メドルビシン、メドロゲストロン(medrogestrone)、メドロン酸、メドロキサロール、酢酸メドロキシプロゲステロン、メドリルアミン、メドリソン、メフェクロラジン、メフェナム酸、メフェニジル、メフェニドラミウム、メフェノレクス、メフェセルピン、メフェキサミド、メフロキン、メフルシド、メガロマイシン(megalomyciin)、メゲストロール、メガス(megace)、メグリチニド、メグルサイクリン、メグルミン、メグルトール、メラドリジン(meladrizine)、メラガトラン(melagatran)、メラルソミン、メラルソニル、メラルソプロール、メルドニウム、メレンゲストロールアセタート、メレチミド、メレボドパ、メリナミド、メリトラセン、メリザム、メロキシカム、メルペロン、メルファラン、メルキナスト、メルアドリン、メマンチン(mamantine)、メモチン、メナビタン、メナジオール、メナジオン、メナドキシム、メナテトレノン、メンブトン、メンフェゴール、メングリタート、メニトラゼパム、メノクトン、メノガリル、メノベンチン(menobentine)、メパジン、メペンゾラート、メペリジン、メフェネシン、メフェノキサロン、メフェンテルミン、メフェニトイン(mephenyloin)、メホバルビタール、メバラール、メピンドロール、メピペルフェニドール、メピプラゾール、メピロキソール、メピチオスタン、メピバカイン、メピキサノクス、メプラミジル、メプレドニゾン、メプロバメート、メプロコール、メプロスシラリン、メプロチキソール、メプリルカイン、メプタジノール、メキドクス、メキノール、メキタミウム、メキタジン、メラジンケート(meradimqate)、アントラニル酸メチル(menthyl anthranilate)、メラフロキサシン、メラレイン、メラルリド、メルバフェン(merbaphen)、メルブロミン、メルカプトメリン、メルカプトプリン、メルクデラミド、メルクフェノール、マーキュマチリン(mercumatilin)、メルゴクリプチン、メリベンダン、メリメポジブ、メロペネム、メルサリル、メルチアリド(mertialide)、メサボロン(mesabolone)、メサラミン、メセクラゾン、メソカルブ、メソリダジン、メシピペロン(mesipiperone)、メスピレノン、メスタノロン、メステロロン、メストラノール、メスジピン、メスレルギン、メスルファミド、メスルフェン、メスプリン、メタブロムサラン、メトブテタミン(metbutethamine)、メタブトキシカイン、メタセタモール、メタクラゼパム、メタクレゾール、メタグ
リコドール、メタヘキサミド、メタルコニウム、メタロール、メタメルファラン、メタンファゾン、メタンフェンプラモン(metamfenpramone)、メタンピシリン、メタニキシン、メタプラミン、メタプロテレノール、メタラミノール、メタキサロン、メタザミド、メタジド、メタゾシン(matazocine)、メトブフェン、メテネプロスト、メテルゴリン、メテルゴタミン、メテスクフィリン(metescufylline)、メテスクレトール、メテシンド、メテトヘプタジン、メトホルミン、メタコリン、メタサイクリン、メサドン、メタジルアセタート、メタレネストリル、メタリブレ、メタルチアジド、メタンフェタミン、メタンドリオール、メタンドロステノロン、メタニアジド、メタンテリン、メタフェニレン、メタピリレン、メタクアロン、メタルビタール、メタスチリドン、メタゾラミド、メトジラジン、メテナミン、メテノロン、メトヘプタジン、メテストロール、メテトイン、メチシリン(methikcillin)、メチマゾール、メチオダール、メチオメプラジン、メチオニン、メチサゾン、メチツラール、メチキセン、メトカルバモール、メトシジン、メトヘキシタール、メトホロン(methopholone)、メトプレン、メトセルピジン、メトトレキサート、メトトリメプラジン、メトキサミン、メトキサレン、メトキシフェドリン、メトキシフェナミン、メトキシプロマジン、メトスコポラミン、メトスクシミド、メチクロチアジド、アミノレブリン酸メチル、パルモキシル酸メチル、サリチル酸メチル、メチルアトロピン、メチルベナクチジン、メチルベンゼトニウム、メチルクロモン(methylcromone)、メチルデソルフィン、メチルジヒドロモルフィン、メチルドパ、メチレンブルー(methylene blie)、メチルエフェドリン、メチルエルゴメトリン、メチルエルゴノビン、メチルパラベン(methyl lparaben)、メチルフェニダート、メチルプレドニゾロン、メチルテストステロン、メチルチオウラシル、メチノジオール、メチプリロン、メチセルギド、メチアミド、メチアピン、メチアジン酸、メチブリド、メチクラン、メチルジゴキシン、メチンジザート、メチオプリム、メチオキサート、メチピロクス、メチプレナリン、メチテピン、メチゾリン、メトケファミド、メトカルコン、メトシニウム、メトクロプラミド、メトクリン、メトフェナザート、メトゲスト、メトラゾン、メトミダート、メトピマジン、メトポン、メトプリン、メトプロロール、メトキジン、メトセルパート、メトスチレノール、メトキセピン、メトラファゾリン、メトラリンドール、メトラジホン、メトレンペロン、メトリボロン、メトリホネート(metrifonate)、メトリフジル、メトリザミド、メトリゾアート、メトロニダゾール(metronidiazole)、メツレデパ、メチラポン、メチロシン、メバスタチン、メキサフィリン、メキサゾラム、メキセノン、メキシレチン、メキシプロシル(mexiprosil)、メキソプロフェン、メコスレノエート(mexrenoate)、メザコプリド、メゼピン、メジラミン、メズロシリン、ミアンセリン(miaanserin)、ミベフラジル、ミボレロン、ミボプラチン、ミカファンギン、ミコナゾール、ミクロノマイシン、ミダフルル、ミダホテル、ミダグリゾール、ミダマリン、ミダキシフィリン(midaxifylline)、ミダゾグレル、ミダゾラム、ミデカマイシン、ミデステイン、ミドドリン、ミドスタウリン、ミフェンチジン、ミフェプリストン、ミホバート、ミグリトール、ミグルスタット、ミカマイシン、ミラカミド(milacamide)、ミラセミド、ミラメリン、ミラタキセル、ミレンペロン、ミルファサルタン、ミリペルチン、ミロキサシン、ミルリノン、ミルテホシン、ミルベリン、ミンバン、ミナルレスタット、ミナメスタン、ミナプリン、ミナキソロン、ミンドジロール、ミンドペロン、ミネペンタート、ミノクロミル、ミノサイクリン、ミノドロン酸、ミノパファント、ミノキシジル、ミオフラジン(mioflaazine)、ミピトロバン、ミプラゴシド、ミプロキシフェン、ミルフェンタニル、ミリンカマイシン、ミリピリウム、ミリプラチン、ミリセトロン(mirisetron)、ミリスタルコニウム、ミロプロフェン、ミロサマイシン、ミロスチペン(mirostipen)、ミルタザピン、ミソニダゾール、ミソプロストール、ミテムシナール、ミチグリニド、ミチンドミド(mitindomine)、ミトブロニトール、ミトカルシン(mitocarcin)、ミトクロミン(mitoclomine)、ミトクロミン(mitocromin)、ミトフラキソン、ミトギリン(mitog
illin)、ミトグアゾン、ミトラクトール、ミトマルシン(mitomalcin)、マイトマイシン、ミトナフィド、ミトポドジド、ミトキドン、ミトスペル(mitosper)、ミトラン(mitolane)、ミトテナミン、ミトキサントロン、ミトゾロミド、ミトラジピド(mitradipide)、ミバクリウム、ミボブリン、ミボチラート、ミキシジン、ミゾラスチン、ミゾリビン、モベカルブ、モベンゾキサミン、モシマイシン、モシプラジン、モクロネミド(moclonemide)、モクタミド、モダフィニル、モダリン、モデカイニド(modecamide)、モジパファント、モエキシプリル、モエキシプリラト、モファロテン、モフェブタゾン(mofebtazone)、モフェギリン、モフェゾラク、モフロベリン、モホキシン(mofoxine)、モフイステイン(mofuisteine)、モルファルナート、モリナゾン、モリンドン、モルラセタム、モリシドミン、モメタゾン、モナラゾン、モナテピル、モネシン(mon
esin)、モノベンゾン、モノクタノイン(monoctanoin)、モノメタクリン、モノホスホチアミン(monophosphothiamine)、モノキセルチン、モンテルカスト、モンテレリン(monterelin)、モペロン、モピダモール、モピドララジン、モプロロール、モキゾン、モランテル、モラゾン、モルクロホン、モルホレクス、モリシジン、モリナミド、モルニフルマート、モロクロメン、モロキシジン、モルフェリジン、モルフィン、モルスクシミド、モサプラミン、モサプリド、モタピゾン、モテキサフィン、モトラゼパム、モトルチニド(motrtinide)、モベルチプリル、モキサドレン、モキサラクタム、モキサプリンジン、モキサスチン、モキサベリン、モキサゾシン、モキセストロール、モキシクモン、モキシデクチン、モキシフロキサシン、モキシルバント、モキシプラキン、モキシラピン(moxirapine)、モキシシレート(moxisylate)、モクスニダゾール、モキソニジン、モザバプタン、モゼナビル、ムブリチニブ(mubritnib)、ムピロシン、ムラブチド、ムラグリタザル、ムレレテカン、ムロカミド(murocamide)、ムゾリミン、ミコフェノール酸、ミファドール、ミロフィン、ミルテカイン、ナバゼニル、ナビロン、ナビタン、ナボクタート、ナブメトン、ナカルトシン、ナダイド、ナジフロキサシン(nadiofloxacin)、ナドロール、ナドキソロール、ナファグレル、ナファモスタット、ナファレリン、ナファザトロム、ナフカプロ酸、ナフシリン、ナフェノドン、ナフェノピン、ナフェトロール、ナフィミドン、ナフィベリン、ナフロコルト、ナホミン、ナホキサドール、ナホキシジン、ナフロニル、ナフタロホス、ナフタゾン、ナフチフィン、ナフトピジル、ナフトキサート、ナフチパミド(naftypamide)、ナグリバン、ナルブフィン、ナルフラフィン、ナリジクス酸、ナルメフェン、ナルメキソン、ナロルフィン、ナロキソン、ナルトレキソン、ナミニジル、ナミンテロール、ナミロテン、ナモキシラート、ナナフロシン、ナンドロロン、ナンテリノン、ナントラドール、ナパクタジン、ナパメゾール、ナファゾリン(naphazaoline)、ナフトノン、ナピリムス、ナピタン、ナプロキシム(naproxime)、ナプロキセン、ナプロキソール、ナプサガトラン、ナラノール、ナラシン、ナラトリプタン、ナルデトテロール(nardetoterol)、ナロパルシル、ナタマイシン、ナテグリニド、ナブリジン、ナキサゴリド、ナキサプロステン(naxaprosteine)、ナキシリン(naxiiylline)、ネアルバルビタール、ネベンタン(nebantan)、ネビドラジン、ネビボロール、ネボグラミン、ネブラセタム、ネブラマイシン、ネコピデム、ネダプラチン、ネドクロミル、ネファゾドン、ネフィラセタム、ネフルモジド、ネホパム、ネララビン、ネルダゾシン、ネレザプリン、ネルフィナビル、ネルテネキシン、ネルザラビン、ネマデクチン、ネマゾリン、ネミフィチド、ネモナプリド、ネモルビシン、ネオシンコフェン、ネオマイシン、ネオスチグミン、ネパズタント、ネパフェナク、ネパプラゾール、ネピカスタット、ネピナロン、ネキナート、ネラメキサン、ネラミノール、ネルバカドール、ネリドロン酸、ネリソパム、ネサピジル、ネシリチド(nesiritide)、ネソステイン、ネスチフィリン、ネチコナゾール、
ネチルミシン、ネチブジン、ネトビミン、ネトグリタゾン、ネツピタント、ニュートラマイシン、ネビパリン(neviparine)、ネキセリジン、ネキソパミル、ナイアシ
ン、ナイアシンアミド、ニアラミド、ニアプラジン、ニブロキサン、ニカフェニン、ニカイノプロール、ニカメタート(nicametane)、ニカナルチン、ニカラベン、ニカルバジン、ニカルジピン、ニセルゴリン、ニセリトロール(niceritol)、ニセベリン、ニクロホラン、ニクロサミド、ニコボキシル、ニコクロナート、ニココジン、ニコルトニド(nicocortonide)、ニコシドジン(nicocidodine)、ニコズオジド(nicoduozide)、ニコフィブラート、ニコフラノース、ニフラテート(nifurate)、ニコグレラート、ニコモール、ニコモルフィン、ニコホリン、ニコラセタム、ニコランジル、ニコチアゾン、ニコトレドール(nicotredole)、ニコキサマト、ニクチアゼム、ニクチンドール、ニドロキシゾン、ニフェジピン、ニフェカラント、ニフェナロール、ニフェナゾン、ニフルム酸、ニフンギン(nifungin)、ニフィラデン(nifiradene)、ニフラルデゾン、ニフラリド、ニフラテル、ニフラトロン、ニフルダジル、ニフレタゾン、ニフルホリン、ニフリミド、ニフリゾン、ニフルマゾール、ニフルメロン、ニフロキン、ニフロキサジド、ニフロキシム、ニフルピポン、ニフルピリノール、ニフルプラジン(nifirprazine)、ニフルキナゾール、ニフルセミゾン、ニフルソール、ニフルチアゾール、ニフルチモクス、ニフルトイノール、ニフルビジン、ニフルジド、ニグルジピン(nigludipine)、ニヒドラゾン、ニケタミド、ニレプロスト、ニルプラゾール、ニルジピン、ニルタミド、ニルバジピン、ニマゾン、ニメスリド、ニメタゼパム、ニミダン、ニモジピン、ニモラゾール、ニムスタン(nimustane)、ネオメタシン(neometacin)、ニペロチジン、ニプラジロール、ニプロファゾン、ニラボリン(nitavoline)、ニリダゾール(nirdazole)、ニスブテロール、ニソバマート、ニソルジピン、ニソキセチン、ニステリム、ニタルソン、ニタゾキサニド、ニテカポン、ニチアミド、ニチシノン、ニトラクリン、ニトロフダン(nitrafudan)、ニトララミン、ニトラミソール、ニトラクァゾン、ニトラゼパム、ニトレファゾール、ニトレンジピン、ニトロセフィン、ニトロクロフェン、ニトロサイクリン、ニトロダン、ニトロフラントイン、ニトロフラゾン、ニトロメルソール、ニトロミド、ニトロミフェン、ニトロスカナート、ニトロビン、ニトロキシニル、ニトロキソリン、ニバゾール、ニビメドン、ニザチジン、ニゾフェノン、ノベラスチン、ノクロプロスト、ノコダゾール、ノフェカミド(nofecamide)、ノガラマイシン、ノラトレキセド、ノリニウム、ノロミロール、ノルピタンチウム、ノメゲストロール、ノメリジン、ノミフェンシン、ノナビン、ノナペロン、ノナピリミン、ノナチムリン、ノニバミド、ノルアシメタドール、ノルボレトン、ノルブドロイン(norbudroine)、ノルコレステノール、ノルクロステボール、ノルコデイン、ノルダゼパム、ノルデフリン、ノルジノン、ノルエルゲストロミン、ノルエピネフリン(norepinepherine)、ノルエタンドロロン、ノルエチンドロン(noethindrone)、ノルエチノドレル、ノルエキシミド、ノルフェネフリン、ノルフロキサシン、ノルゲステロン、ノルゲスチマート、ノルゲストメト、ノルゲストレル、ノルゲストリエネオン(norgestrieneone)、ノルレチモール、ノルレボルフェノール(norlevorphenol)、ノルメサドン、ノルモルフィン、ノルピパノン、ノルテトラゼパム、ノルトピキサントロン、ノルトリプチリン、ノルビニステロン、ノサンチン、ノスカピン、ノシヘプチド、ノボビオシン、ノキシプチリン、ノキシチオリン、ヌクロメドン、ヌクロキセチン(nuclotixene)、ヌフェノキソール、ヌパファント、ヌベンゼピン、ニレストリオール、ニリドリン、ナイスタチン、オビドキシム、オカペリドン、オクフェンタニル、オシルチド、オシナプロン、オクタカイン、オクタホニウム、オクタモキシン、オクタピノール、オクタスチン(octatine)、オクタベリン、オクタザミド、オクテニジン、オクチシゼル、オクチミバート、オクチノキサート(octinoxate)、オクチサレート(octisalate)、オクトクリレン、オクトドリン、オクトパミン、オクトチアミン、オクトレオチド、オクトリプチリン、オクトリゾール(octriazole)、オダルプロフェン、オダピパム、オジパルシル、オフロキサシン、オフォミン(ofomine)、オフタスセイン、オグルファニド、オラフルル、オラムフロキサシン、オラネキシジン、オ
ランザピン、オラキンドクス、オルセゲパント、オレアンドマイシン、オレチモール、オルメサルタン、オロパタジン、オルパドロン酸、オルピメドン、オルプリノン、オルラジピン、オルサラジン、オルチプラズ、オルバニル、オマシクロビル、オマパトリラト(omapartrilat)、オメプラゾール、オミドリン、オミガピル、オミロキセチン、オモコナゾール、オモナステイン、オナプリストン、オンダンセトロン、オンタゾラスト、オンチアニル、オパニキシル、オパビラリン、オピニアジド、オピプラモール、オプラトニウム、オラザミド、オラジポン、オルボフィバン、オルブトプリル、オルコナゾール、オリエンチパルシン(orientiparcin)、オリタバンシン、オルリスタット、オルマプラチン、オルメロキシフェン、オルメトプリム(ormetoprin)、オルニダゾール、オルニプレッシン(ornipreessin)、オルニチン、オルノプロスチル、オロチン酸、オロチレリン、オルパノキシン、オルフェナドリン、オルタタキセル、オルテタミン(orteteamine)、オサネタント、オサテロン、オセルタミビル、オセモゾタン、オスマジゾン、オスペミフェン、オストレオグリシン、オスチジン、オタミキサバン、オテンゼパド、オテラシル、オチロニウム、オチメラート、ウアバイン、オキサボロン、オキサブレキシン、オキサセプロール、オキサシリン、オキサジメジン、オキサフロザン、オキサフルマジン、オキサグレラート、オキサリナスト、オキサリプラチン、オキサマリン、オキサメタシン、オキサミソール、オキサミニキネム(oxaminiquinem)、オキサナミド、オキサンドロロン、オキサンテル、オキサパドール、オキサピウム、オキサプラジン(oxaprazine)、オキサプロチリン、オキサプロジン、オキサカルバゾール(oxcarbazole)、オキサトミド、オキサザホン、オキサゼパム、オキサジドン(oxazidone)、オキサゾラム、オキサゾロン、オクスカルバゼピン、オクスドララジン、オキセクロスポリン、オキセドリン、オキセグリタザル、オキセラジン、オキセンドロン、オキセピナク、オキセタシリン、オキセサジン(oxethazine)、オキセトロン、オクスフェンダゾール、オクスフェニシン、オキシベンダゾール、オキシベタイン、オキシコナゾール(oxiconizole)、オキシドーパミン(oxidapamine)、オキシドロン酸、オキシフェントレクス(oxfentorex)、オキシフンギン、オキシグルタチオン(oxigluttione)、オキシロフリン、オキシロルファン、オキシモナム、オキシンダナク、オキシニアク酸、オキシペロミド(oxperomide)、オキシラセタム、オキシラミド、オキシソプレド、オキシスラン、オキシテホニウム、オキシトリプタン、オキシトリプチリン、オキシトリポニウム(oxtriponium)、オクスメチジン、オキソジピン、オキソゲストン、オキソラミン、オキソリン酸、オキソメマジン(oxomermazine)、オキソナジン、オキソフェナルシン、オキソプロストール(oxoprosto;l)、オクスフェネリジン、オクスプレノアート、オクスプレノロール、オキシトリフィリン(oxtriphylline)、オキシベンゾン(oxbenzone)、オキシブチニン、オキシクロロセン(oxychlorosene)、オキシシンコフェン、オキシクリピン、オキシクロザニド、オキシコドン、オキシジペントニウム、オキシフェドリン、オキシメステロン、オキシメタゾリン、オキシメタロン(oxymethalone)、オキシモルフォン、オキシペンジル、オキシペルチン、オキシフェンブタゾン、オキシフェンサイクリミン、オキシフェニサチン、オキシフェノニウム、オキシプリノール、オキシピロニウム(oxypurronium)、オキシキノリン、オキシリダジン、オキシソニウム、オキシテトラサイクリン、オキシトシン、オザグレル、オザガマイシン、オゾリノドン(ozolindone)、パクリタキセル、ブシンドロール(pacrindolol)、パクチミブ、パジマートA、パジマートQ、パフェノロール、パゴクロン、パルジマイシン、パリナビル、パリペリドン、パルミドロール、パルモキシレート、パロニジピン、パロノセトロン(palonosertron)、パロスラン、パマブロン(pamabron)、パマクエシド、パマキン(pamaquin)、パミコグレル、パミドロン酸、パナジプロン、パナメシン、パンコプリド、パンクロニウム、パニペネム、パノミフェン、パンテニカート、パンテチン、パンテノール、パントプラゾール、パヌラミン、パパベリン(papverine)、パパベロリン(p
apveroline)、パラクロロフェノール(parachlorphenol)、パラフルチジド(parafiutizide)、パラメタジオン、酢酸パラメタゾン、パラニトロスルファチアゾール(paranitrosulfathiazole)、パラニリン、パラペンゾラート、パラプロパモール、パラロザリニン、パラキサゾン、パルベンダゾール、パルセタサール、パルコナゾール、パレコキシブ、パレプチド、パレトキシカイン、パルゲベリン、パルゴロール、パルギリン、パリカルシトール、パリドカイン、パロジロール、パロモマイシン、パロキセチン、パロキシプロピオン、パルサルミド、パルチシン(particin)、パルバクォン、パシニアジド、パシレオチド、パタモスタット、パツピロン(patupilone)、パウロマイシン、パキサマート、パゼリプチン、パジナクロン、パゾキシド、パズフロキサシン、ペシロシン、ペコサイクリン、ペフロキサシン(pefloxocin)、ペランセリン、ペルデシン、ペプロマイシン(peliomycin)、ペリチニブ、ペリトレキソール、ペルレチン、ペルリノン、ペルビプロフェン(pelubiprofen)、ペメドラク、ペメリド、ペメトレキセド、ペミロラスト、ペモリン、ペナメシリン、ペンブトロール、ペンシクロビル、ペンデカマイン(pendecamine)、ペンデチド、ペンフルリドール、ペンフルチジド、ペンギトキシン、ペニシラミン、ペニシリンG、ペニシリンV、ペニメピサイクリン(penimepicycline)、ペニモシクリン、ペニロロール、ペンメステロール(penmesterol)、ペノクトニウム、ペンプロステン、ペンタバマート、ペンタシニウム、ペントフルラノール(pentfluranol)、ペンタガストリン、ペンタゲストロン(pentagestrone)、ペンタラミド、ペンタメトニウム、ペンタミジン、ペンタモルフォン、ペンタモキサン、ペンタムスチン、ペンタピペリド、ペンタピペリウム、ペンタキン、ペンタゾシン、ペンテト酸、ペントレオチド(pentreotide)、ペンチエナート、ペントリクロラール、ペンチアピン、ペンチフィリン、ペンチゲチド、ペンチソミシン、ペンチソミド(pentisomeide)、ペンチジドン、ペントバルビタール、ペントリニウム、
ペントロニウム、ペントモン、ペントプリル、ペントレクス、ペントサレン(pentosalen)、ペントスタチン、ペントキシフィリン、ペントキシベリン、ペントリニトロール、ペンチレンテトラゾール、ペプロマイシン、ペプスタチン、ペラクロポン、ペラドキシム、ペラフェンシン、ペラロプリド、ペラミビル、ペラキシン(peraquisin)、ペラスチン、ペラチゾール、ペラジン(perazine)、ペルブフィリン(perbufylline)、ペルホメジル、ペルホスファミド、ペルゴリド(pegolide)、ペルヘキシリン(perhexyline)、ペリシアジン、ペリホシン、ペリメタジン、ペリンドプリル、ペリンドプリラト、ペリソキサール、ペルラピン、ペルメトリン、ペロスピロン、ペルフェナジン、ペルシル酸、ペルジンホテル、ペトリクロラール、ペキサンテル、ファンクオン、フェナカイン、フェナセミド、フェナセチン、フェナクトロピニウム、フェナドキソン、フェナグリコドール、フェナマゾリン、フェナンプロミド、フェナフタジン(phenaphthazine)、フェナルソン、フェナゾシン、フェナゾピリジン、フェンブタゾン、フェンカルバミド、フェンシクリジン、フェンジメトラジン、フェネルジン、フェネリジン、フェネチシリン、フェネツリド、フェニルグルタルイミド(phenylglutarimide)、フェニカルバジド、フェニンダミン、フェニンジオン、フェニプラジン、フェニラミン、フェニソノン、フェンメトラジン、フェノバルビタール、フェノブチオジル、フェノモルファン、フェノチアジン、フェノトリン、フェノキシベンズアミン、フェノキシプロパジン、フェンプロバマート、フェンプロクモン、フェンプロメタミン、フェンスキシミド、フェンテルミン、フェントラミン、フェニルアミノサリチル酸、フェニルアラニン、フェニルブタゾン、フェニレフリン、フェニルプロパノールアミン、フェニルチオロン(phenylthiolone)、フェニルトロキサミン、フェニラシリン(phenyracillin)、フェニラミドール、フェニトイン(phenyloin)、ペントバルビタール(pnetharbital)、ホルコジン、フォレドリン、ホキシム、フタロフィン、フタルスルファセタミド(phthylsulfacetamide)、フタリルスルファメチゾール(ph
thalylsulfamethiazole)、フタリルスルファチアゾール、フィゾスチグミン、フィチン酸、フィトナジオン、ピバキシジン、ピベカルブ、ピベラリン、ピボセロド、ピブロゼレシン、ピブチジエン(pibutidien)、ピカフィブラート、ピカルタミド、ピセナドール、ピシロレクス、ピクラミラスト、ピクロニジン、ピクロパスチン、ピクロキシジン、ピコベンジド、ピコドララジン、ピコラミン、ピコノール、ピコペリン、ピコプラチン、ピコプラゾール、ピコタミド、ピコトリン、ピクマスト、ピクメテロール、ピドベンゾン、ピドラセタモール、ピドール酸(pidolicaicd)、ピドチモド、ピファミン(pifamine)、ピフィネート(pifinate)、ピフェキソール、ピフルチキソール、ピケトプロフェン、ピルドララジン、ピロカルピン、ピルシカイニド(pilsicamide)、ピマゲジン、ピメクロン、ピメクロリムス、ピメチリン(pimethylline)、ピメラウチド、ピメタシン、ピメチキセン、ピメチン、ピメトレミド(imetremide)、ピミルプロスト、ピミノジン、ピモベンダン、ピモニダゾール、ピモジド、ピナシジル、ピナドリン、ピナフィド、ピナベリウム、ピナゼパム、ピンカミド(pincamide)、ピンドロール、ピノカラント、ピノールカイン、ピノキセピン(pinoxepine)、ピオグリタゾン、ピパサイクリン、ピパマジン、ピパンペロン、ピパゼタート、ピペブゾン、ピペクロニウム、ピペミド酸、ピペンドキシフェン、ピペンゾラート、ピペクァリン、ピペラセタジン、ピペラシリン、ピペラミド、ピペリドラート、ピペリラート、ピペロカイン、ピペロニルブトキシド、ピペロキサン、ピペルフェニドール(piperphenidol)、ピペリロン、ピポブロマン、ピポクタノン、ピポフェジン、ピポスルファン、ピポチアジン、ピポキシジン、ピポキソラン、ピプラジマドール、ピプラドロール、ピプラマドール、ピプラテコール、ピプリヒドリナート(piprinhydrinate)、ピポクラリウム(pipocurarium)、ピプロフロール、ピプロゾリン、ピキンドン、ピキジル、ピラセタム、ピランダミン、ピラルビシン、ピラキセラート、ピルズモナム(pirzmonam)、ピラゾラク、ピルベニシリン、ピルブテロール、ピルドニウム、ピレノキシン、ピレンペロン、ピレンゼピン(pirezepine)、ピレポロール、ピレタニド、ピルフェニドン、ピリベジル(pirbendil)、ピリジシリン、ピリドカイン、ピリドキシラート、ピリドロン酸、ピリフィブラート、ピリミホスエチル、ピリンダゾール(pirindazole)、ピリニクス酸、ピリニキシル、ピリプロスト、ピリクァロン、ピリスダノール、ピリトラミド、ピリトレキシン(piritrexin)、ピルリマイシン、ピルリンドール、ピルマグレル、ピルメノール、ピルナビン、ピロクトン、ピロダビル、ピリオドマスト(priodomast)、ピログリリド、ピロヘプチン、ピロラート、ピロラザミド、ピロミド酸、ピロキサントロン、ピロキシカム、ピロキシシリン、ピロキシモン、ピロザジル、ピルプロフェン、ピルキノゾール、ピラルコニウム、ピルシドミン、ピルテニジン、ピテノジル、ピトフェノン、ピツキサート、ピバガビン、ピバンピシリン、ピベンフリン、ピボプリル、ピボキサゼパム、ピキサントロン、ピゾチリン、プラフィブリド(plafbride)、プラウノトール、プラウラシン(plauracin)、プレコナリル、プレウロムリン、プレビトレキセド、プリカマイシン(plicamuycin)、プロメスタン、ポビルカスト(pobilukast)、ポジルフェン、ポドフィロックス、ポルジン、ポリミキシン、ポリチアジド、ポミサルタン、ポナルレスタット、ポナズリル、ポンフィブラート、ポルフィロマイシン、ポサコナゾール、ポサチレリン、ポシゾリド、ポスカイン(poskine)、プラクトロール、プラドフロキサシン(pradolfoxacin)、プラジマリン(prajmalium)、プララトレキサート、プラリドキシム、プラルモレリン、プラルナカサン、プラミペキソール、プラミラセタム、プラモキシン、プラミピン(prampine)、プラナゼピド、プラニジピン、プランクラスト(prankulast)、プラノリウム、プラノプロフェン、プラノサール、プラステロン、プラスグレル、プラトサルタン、プラバドリン、プラバスタチン、プラキサジン、プラザレリクス、プラゼパム、プラゼピン、プラジカンテル、プラジトン、プラゾシリン、プラゾシン、プレクラモール、プレドナザート(prednazate)、プレドナゾリン(prednazoline)、プレドニ
カルバート、プレドニムスチン、プレドニゾラマート(prednisolamate)、プレドニゾロン、プレドニゾン、プレドニバール、プレドニリデン、プレガバリン、プレグナジオール(pregnadiol)、プレグネノロン、プレマフロキサシン、プレマゼパム、プレナルテロール、プレニステイン、プレノベリン、プレノクスジアジン、プレニラミン、プレタマジウム、プレチアドイル(pretiadoil)、プレザチド、プリベカイン、プリデフィン、プリデペロン、プリジノール、プリフェロン、プリフィニウム、プリフロリン、ピロカイン(pilocalne)、プリマペロン、プリマキン、プリミドロール、プリミドン、プリマイシン、プリノマスタット、プリノミド、プリノキソダン、プリスチノール(pristinol)、プリスチナマイシン、プリジジロール、プロアジフェン、プロバルビタール、プロベネシド、プロビクロミル、プロブコール、プロカインアミド、プロカイン、プロカルバジン、プロカテロール、プロクロルペラジン、プロシノロール、プロシノニド、プロクロノール、プロクロミル(procromil)、プロシクリジン、プロシマート、プロデコニウム、プロジリジン、プロジピン、プロドール酸、プロファドール、プロフェキサロン、プロフラビン、プロフラゼパム、プロガビド、プロゲステロン、プログルメタシン、プログルミド、プロヘプタジン、プロリゲストン、プラリン(praline)、プロリンタン、プロロニウム、プロマジン、プロメゲストン、プロメストリエン、プロメタジン、プロモラート、プロモキソラン、プロンタロール(prontalol)、プロパセタモール、プロパフェノン、プロパゲルマニウム、プロパミジン、プロパニジド、プロパノカイン、プロパンテリン、プロパラカイン、プロパチルニトラート、プロパゾラミド、プロペニダゾール、プロペントフィリン(proprntofylline)、プロペンゾラート、プロペリジン、プロペタミド、プロペタンホス(propetamfos)、プロペタンドロール(propetandrol)、プロピシリン、プロピカシン、プロピネチジン、プロピオマジン、プロピポカイン(propiocaine)、プロピラム、プロピセルギド、プロピベリン、プロピゼピン、プロポフォール、プロポキサート、プロポキスル、プロポキシカイン、プロポキシフェン、プロプラノロール、ドセトリゾ酸プロピル、没食子酸プロピル、プロピルヘキセドリン、プロピリオドン、プロピルチオウラシル、プロピペロン、プロピフェナゾン、プロピロマジン、プロクァゾン、プロキノラート、プロレノアート、プロロキサン、プロスシラリジン(prscillardin)、プロスピジウム、プロスタレン、プロスルプリド、プロスルチアミン、プロテルグリド、プロテオブロミン(protheobromine)、プロチペンジル、プロチキセン、プロチオファート、プロチオナミド、プロチレリン、プロチジン酸、プロトキロール、プロトポルフィリン、プロトリプチリン、プロキサゾール(proxzole)、プロキシバルバール、プロキシブテン、プロキシクロミル、プロキシフェゾン、プロキソルファン、プロキシメタカイン、プロキシフィリン、プロザピン、プルカロプリド、プルリフロキサシン、プルバンセリン、プソイドエフェドリン、プマフェントリン、プマプラゾール、プミテパ、プモセトラグ、ピューロマイシン、ピラブロム(pyrabrom)、ピランテル、ピラチアジン、ピラジナミド、ピラゾフリン、ピリカルバート、ピリダロン、ピリジノール、ピリドフィリン(pyridofylline)、ピリドスチグミン、ピリドキサール、ピリドキサミン、ピリドキシン、ピリラミン、ピリメタミン、ピリマート(pyrimate)、ピリノリン、ピリチオン、ピリチルジオン、ピリチジウム、ピリチノール、ピロフェンインダン(pyrophenindane)、ピロバレロン、ピロキサミン、ピロブタミン、ピロカイン、ピロリフェン、ピロリフェン(pyrroliphene)、ピロールニトリン(pyrroInitrin)、ピロキサン(pyrroxane)、ピルビニウム、ピタミン、クァダゾシン、クァドロシラン、カタカイン、クァゼパム、クァジノン、クァゾジン、クァゾラスト、クエチアピン、キフェナジン、キフラポン、キリホリン、キロスチグミン、キナカイノール、キナシリン、キナクリン、キナゴリド、キナルジンブルー、キナプリル、キナプリラト、キナゾシン、キボロン(quibolone)、キンカルバート、キンデカミン、キンドニウム、キンドキシン、キネロラン、キネストラドール、キネストロール、キネタゾン、キネトラート(quinetolate)、キネザミド、キンファミド、酢酸キン
ゲスタノール、キンゲストロン、キニジン、キニン、キノトラスト、キンピロール、キンテレノール、キチオホス(quitiofos)、キヌクリウム、キヌプラミン、キヌプリスチン、キパジン、キスルタジン、ラベプラゾール、ラクロプリド、ラクトパミン、
ラダファキシン、ラホキサニド、ラガグリタザル、ラリトリン、ラロキシフェン、ラルチトレキセド、ラルリジン、ラマトロバン、ラムシクラン、ラメルテオン、ラミフェナゾン、ラミプリル、ラミプリラト、ラミキソチジン、ラムノジギン、ラモプラニン(ramnoplanin)、ラモレリックス、ラモセトロン、ラネル酸、ラニムスチン、ラニマイシン(ranimycin)、ラニレスタット、ラニチジン、ラノラジン(ranolaine)、ラパクロニウム、ラサギリン、ラスブリカーゼ、ラチロニン、ラブコナゾール、ラザキサバン、ラジノジル、ラゾバザム、ラゾキサン、レビマスタット、レボキセチン、レカイナム、レクラゼパム、レガデノゾン、レグリタザル、レルコバプタン、レロマイシン、レマセミド、レミフェンタニル、レミキレン、レミプロストール、レモキシプリド、レナノロン、レンチアプリル、レンザプリド、レパグリニド、レパリキシン、レピノタン、レピリナスト、レプロマイシン、レプロテロール、レシメトール、レシンナミン、ラセキニル(resequinil)、レセルピン、レジキモド、レソコルトールブチラート(resocortol butyrate)、レソランテル、レゾルシノール、レタパムリン、レテリプチン、レチガビン、レチノール、レバプラザン、レバトロパート、レベナスト、レビパリン、レビジノン、レボスピロン、リバビリン、リボフラビン、リボプリン、リボスタマイシン(ribostamuycin)、リカセトロン、リダゾロール、リドグレル、リファブチン、リファラジル、リファメタン、リファメキシル、リファミド、リファンピン、リファペンチン、リファキシミン、リラピン、リルマカリム、リルマザホン、リルメニジン、リロピロクス、リロザロン、リルピビリン(rilpovorine)、リルゾール、リマンタジン、リマゾリウム、リムカゾール、リメキソロン、リミテロール、リモナバント、リモプロギン、リオジピン、リオプロスチル、リパゼパム、リピサルタン、レザレスタット、リセドロン酸、リソカイン、リソチリド、リスペンゼピン、リスペリドン、リスチアノール、リストセチン、リタンセリン、リトメタン(ritometan)、リチペネム、リトベグロン、リトドリン、リトルカスト、リトナビル、リトロピロニウム、リトロスルファン、リバロキサバン、リバスチグミン、リボグリタゾン、リザトリプタン、ロバルゾタン、ロベニジン、ロカスチン、ロセパファント、ロシクロビル、ロクロニウム、ロドカイン、ロドルビシン、ロフェコキシブ、ロフェロジン、ロフレポニド、ロフルミラスト、ログレチミド、ロキタマイシン、ロラファグレル、ロレタミド、ロルガミジン、ロリシクリジン、ロリシプリン、ロリプラム、ロリテトラサイクリン、ロロジン、ロルジラセタム、ロマザリット、ロメルゴリン、ロミフェノン、ロミフィジン、ロムルチド、ロナクトロール、ロニダゾール、ロニフィブラート、ロニパミル、ランネル(runnel)、ロピニロール、ロピトイン、ロピバカイン、ロピジン、ロキニメクス、ロサプロストール、ロサラミシン、ローズベンガル、ロシグリタゾン、ロソキサシン、ロスタフロキシン、ロスタポルフィン、ロステロロン(rosterolone)、ロスバスタチン、ロタミシリン、ロチゴチン、ロトキサミン、ロトラキサート(rotaxate)、ロキサジマート、ロキサルソン、ロキサチジンアセタート、ロキシボロン、ロキシフィバン、ロキシンドール、ロキシスロマイシン、ロキソロニウム、ロキソペロン、ルビテカン、ルボキシスタウリン、ルフィナミド、ルフロキサシン、ルパタジン、ルピントリビル、ルタマイシン、ルバゾン、ルザドラン、サバルビシン、サブコメリン、サベルゾール、サビポリド、サッカリン、サフィンゴール、サフィリノール(safirinol)、サガンジピン、サラセタミド、サラフィブラート、サランテル、サラゾジン、サラゾスルファジミジン、サラゾスルファミド、サラゾスルファチアゾール、サルカプロジン酸(salcaprozoic acid)、サルコレクス、サレタミド、サルフルセリン(salflucerine)、サリチルアルコール、サリチルアミド、サリチル酸、サリナジド、サリノマイシン、サルメファモール、サルメテロール、サルミステイン、サルナセジン、サルプロトシド、サルサラート、サメリジン、サミキソグレル、サンパトリラット、サンピルチン、サンサイクリン、サンフェトリネム、サングイナリウム、サペ
ルコナゾール、サプリサルタン、サプロプテリン、サキナビル、サラフロキサシン、サラカリム、サララシン、サルコリシン、サルドモジド、サレズタント、サリペデム(saripedem)、サリゾタン、サルマゼニル、サモキシシリン(samoxicillin)、サルピシリン、サルポグレラート、サテリノン、サチグレル、サトラニダゾール、サトラプラチン、サビプラゾール、サボキセピン、スコパフンギン、スコピナスト、スコポラミン、セカルシフェロール、セクラゾン、セクニダゾール、セコバルビタール、セクリニン、セデカマイシン、セドキサントロン(sedoxantrone)、セガンセリン、セゲステロン(segesterone)、セグリチド、セラメクチン、セレギリン(selgiline)、セルホテル、ソルデノソン(soldenoson)、セルプラジン、セマピモド(sampimod)、セマチリド、セマキサニブ、セムズラマイシン、セモルホン、セモチアジル、セムスチン、セナゾダン、セオカルシトール、セパゾニウム、セペリドール、セピモスタット、セプリロース、セプロキセチン、セキフェナジン、セラトロダスト、セラザピン、セルフィブラート、セルゴレキソール、セルメタシン、セルチンドール、セルトラリン、セタスチン、セチンドール(setzindol)、セチパファント、セチプチリン、セトペロン、セビトロピウム(sevitropium)、セボプラミド、セザラミド(sezalamide)、サゴシド(sagoside)、シベナデト、シボピルジン、シブラフィバン、シブトラミン、シッカニン、シフルプラジン(sifrprazine)、シグアゾタン、シランドロン、シルデナフィル、シリビニン、シルクリスチン(silcristin)、シルジアニン(sildianin)、シロドシン、シロドラート(silodrate)、シルペリソン、シルテンゼピン、シメンダン、シメトリド、シンフィブラート、シムトラゼン、シンバスタチン、シンカリド、シネフンギン、シニトロジル、シントロピウム(sintropium)、シパトリギン、シラメシン、シラチアゼム、シロリムス、シソミシン、シタフロキサシン、シタリドン、シタマキン、シタキセンタン、シトフィブラート、シトグルソイド(sitoglusoide)、シベレスタット、ソブリドチン、ソブゾキサン、ソラベグロン、ソリフェナシン(solifenasin)、ソリマスタット(solimastat)、ソルペカイノール、ソリペルチン、ソマタジン(somatadine)、ソネクロザン、ソネピプラゾール、ソピタジン、ソプロミジン、ソキノロール、ソラフェニブ、ソラプラザン、ソルビニカート、ソルビニル、ソリブジン、ソルニジピン、ソタロール、ソテレノール、スパグルム酸、スパルフロキサシン、スパルホサート、スパルソマイシン、スパルテイン、スペクチノマイシン、スピクラミン、スピペロン、スピラドリン、スピラミド、スピラマイシン、スピラプリル、スピラプリラト、スピレンドロール、スピルゲチン、スピリレン、スピリプロスチル、スピロフィリン(spirofylline)、スピロゲルマニウム、スピログルミド、スピロムスチン、スピロノラクトン、スピロプラチン、スピロレノン、スピロトリアジン(spirotriazine)、スピロキサソン、スピロキサトリン、スピロキセピン、スピゾフロン、スピロジアミン(sprodiamine)、スクアラミン、スクアラン、スタコフィリン(stacofylline)、スツルマイシン(stllimycin)、スタンスポルフィン(stannsoprfin)、スタノロン(stanolone)、スタノアオロール(stanoaolol)、スタブジン、ステアリルスファミド(stearylsufamide)、ステフィマイシン、ステンボロン、ストルプロニン(strpronin)、ステルクロニウム、ステバラジル、スチバミン、スチボフェン(stibophen)、スチルバミジン、スチルバジウム、スチロニウム、ストリマゾール(strimazole)、スチリペントール、スチロカミド(stirocamide)、スチロホス、ストレプトマイシン、ストレプトニコジド(streptonicozid)、ストレプトニグリン、ストレプトゾシン、スチラミン(styramine)、スバチアゾン(subathiazone)、スベンダゾール、スクシニルコリン、スクシニルスルファチアゾール、スクシスルホン、スクロフェニド、スクラルファート、スクラロース、スクロースオクタアセタート、スクロスルフェート(sucrosufate)、スデキサノクス、スドキシカム、スフェナチル(sufenatil)、スホチジン、スフゴリクス、スガマデクス、スラムセロド
、スラゼパム、スラズリル、スルバクタム、スルベニシリン、スルベノクス、スルベンチン、スルブチアミン、スルクラミン(sulclamine)、スルコナゾール、スルファベンズ、スルファベンズアミド、スルファブロモメタジン、スルファカルバミド、スルファセコール、スルファセタミド、スルファクロルピリダジン、スルファクリソイジン、スルファクロミド、スルファクロラゾール、スルファクロジン、スルファシチン、スルファジアジン、スルファジメトキシン、スルファドキシン、スルファエチドール、スルファグアニジン、スルファグアノール、スルファレン、スルファロクス酸、スルファマゾン、スルファメラジン(suifamerazine)、スルファメトル、スルファメタジン(sulfamethaziine)、スルファメチゾール、スルファメトキサゾール、スルファメトキシピリダジン、スルファメトミジン(sulfametmidine)、スルファメトロール、スルファモノメトキシン、スルファモキソール、スルファニルアミド、スルファニレート(sulfanilate)、スルファニトラン(sulfaanitran)、スルファペリン、スルファフェナゾール、スルファプロキシリン、スルファピリジン、スルファキノキサリン、スルファルスフェナミン、スルファサラジン、スルファソミゾール、スルファスクシナミド、スルファシマジン、スルファチアゾール、スルファチオ尿素、スルファトラミド、スルファトロキサゾール、スルファトロゾール、スルファザメト、スルフィナロール(sulfinaolol)、スルフィンピラゾン、スルフラム(sulfuram)、スルフィソミジン、スルフィソキサゾール、スルホブロモフタレイン、スルホンテロール、スルホリダジン、スルホサリチル酸、スルホキソン、スルクリナト(sulcrinat)、スリンダク、スリサチン、スリソベンゾン、スルマリン、スルマゾール、スルメプリド、スルニダゾール、スロカルビラート、スロクチジル、スロデキシド(sulodexide)、スロフェヌル、スルペネム、スロセミド、スロトロバン、スロキシフェン、スルピリド、スルプロサール、スルプロストン、スルタミシリン、スルチアム、スルトプリド、スルトシル酸、スルトロポニウム(sultroponium)、スルカスト、スルベラプリド、スマセタモール、スマニロール、スマロテン、スマトリプタン、
スメチジド、スナグレル、スンシリン、スネピトロン、スピジミド、スプラタスト(supalast)、スプロクロン、スプロフェン、スラミン、スリカミド(suricamide)、スリクロン、スリトゾール、スロナクリン、スサリモド、スキセメリド、スキセトニウム、スキシブゾン、シムクロセン、シメチン(synetine)、タビラウチド、タビモレリン、タカルシトール、タカペネム(tacapenem)、タセジナリン、タクラミン、タクリン、タクロリムス、タダラフィル、タフルポシド、タグルタミン(taglutamine)、タゴリジン、タランパネル、タランピシリン、タラポルフィン、タラスチン、タルブタール、タレラノール、タリベグロン、タリノロール、タリペキソール、タリソマイシン、タリムスチン、タルメタシン、タルメトプリム、タルネタント、タルニフルマート、タロプラム、タロサラート(talsalate)、タロキシミン(toloximine)、タルサクリジン、タルスプラム、タルチレリン、タルトブリン、タルトリミド、テルジピン(taludipine)、タルビラリン、タメリドン(tameridone)、タメチシリン、タメトラリン、タミバロテン、タミチノール、タモラリジン(tanolarizine)、タモキシフェン、タンプラミン、タムスロシン、タナプロゲト、タンダミン、タンドスピロン、タンデュチニブ、タニプロン、タノマスタット、タペンタドール、タプリゾシン、タプロステン、タラゼピド、タリキダル(tariquindar)、タソサルタン、タスルジン、タウロリジン、タウロムスチン、タウロセルコール酸、タウロステイン、タザドレン、タザノラスト、タザロテン、タザスブラート、タゼプロフェン、タジフィリン、タジプリノン、タゾバクタム、タゾフェロン、タゾロール、タゾメリン(tazometine)、テバニクリン、テバチゾール、テビペネム、テブフェロン、テブキン、テカデノゾン、テカルセト、テカステミゾール、テクロチアジド(teclthiazide)、テクロザン、テジサミル、テファゾリン、テフェンペラート、テフルダジン(teflufazine)、テフルチキソール(tefiutixol)、テガフール、テガセロド、テグリカル、テイコプラニン(tei
copanin)、テラバンシン、テルビブジン、テレンゼピン、テリナビル、テリスロマイシン、テルメステイン、テルミサルタン、テロキサントロン、テルジピン、テマフロキサシン(temafioxacin)、テマロテン、テマロピウム、テマゼパム、テメホス、テメラスチン、テミベリン、テモカプリル、テモカプリラト、テモシリン、テモドクス、テモポルフィン、テモゾロミド、テムシロリムス(temisirolimus)、テムルチド、テナンフェタミン、テナトプラゾール、テンダミスタット、テニダップ、テニラピン、テニロキサジン、テニルセタム、テニポシド、テニバスタチン、テノシクリジン、テノホビル、テノホビルジソプロキシル、テノニトロゾール、テノサール、テノシプロール、テノキシカム、テニリドン、テオプランチル(teoprantil)、テオプロロール、テピリンドール、テポキサリン、テプレノン、テプロチド、テラゾシン、テルベキニル、テルビナフィン、テルボグレル、テルブクロミル、テルブフィロール(terbufirol)、テルブフィシン、テルブプロール、テルブタリン、テルシプラジン、テルコナゾール、テルデカマイシン、テレスチグミン(teerestigmine)、テルフェナジン(terfeadine)、テルフラボキサート(terfiavoxate)、テルフルラノール(terfuranol)、テルグリド、テリフルノミド、テリカラント、テリジドン、テルラキレン、テルリプレシン、テルニダゾール、テロジリン、テロフェナマート、テロキサレン、テロキシレン、テルタトロール、テサグリタザル、テシカム、テシミド、テスミリフェン(tesimilifene)、テソフェンシン、テストラクトン、テストステロン、テトミラスト(tetomilst)、テトラバルビタール、テトラベナジン、テトラカイン、テトラサイクリン、テトラヒドロゾリン、テトラメトリン、テトラミソール、テトラキセタン、テトラゼパム、テトラゾラスト、テトリプロフェン、テトロホスミン、テトロナシン、テトロキノン、テトロキソプリム(tetroxoprin)、テトリダミン、テベレリクス、テキサクロミル、テザシタビン、テゾセンタン、サリドマイド、テバコン、テナリジン、テニウム、テニルジアミン、テオブロミン、テオドレナリン、テオフィブラート、テオフィリン、チアベンダゾール、チアセタルサミド、チアルバルビタール、チアマゾール、チアミン、チアミプリン、チアンフェニコール、サミラル、チアゼシム、チアジナミウム、チアゾールスルホン、チエチルペラジン(thiethyperazine)、チヘキシノールエチルブロミド(thihexinol ethylbromide)、チメルホナート、チメロサール、チオコルチコシド、チオクト酸、チオフラデン、チオグアニン、チオヘキサミド、チオイノシン、チオペンタール、チオファナート、チオプロパザート、チオプロペラジン、チオリダジン、チオサラン、チオストレプトン(thiostrpton)、チオテパ、チオテトラバ
ルビタール、チオチキセン(thiothixene)、チフェナミル、チフェンシリン、チラム、トンゾニウム、トンジルアミン、トザリノン、スレオニン、チモカルチン、チモクトナン、チモール、チモペンチン、チモトリナン、チロメダン(thyromedan)、チロプロプ酸、サイロキシン、チアクリラスト、チアデノール、チアフィブラート、チアガビン、チアメニジン、チアメトニウム(tiametomnium)、チアムリン、チアナファク、チアネプチン、チアパミル、チアピリノール、チアプリド、チアプロフェン酸、チアプロスト、チアラミド、チアゾフリン、チアズリル、チアバロシン(tiabalosin)、チベグリセン、チベネラスト、チベンザート、チベゾニウム、チボロン、チブル酸、チブロファン、チカベシン(ticabesine)、チカロプリド、チカルボジン、チカルシリン、チクラトン、チクロピジン、チコルバント、チクリナフェン、チデンベルサト、チジアシク酸(tidiacic acid)、チエモニウム、チエノカルビン、チエノプラミン、チエノキソロール、チフェモキソン、チフェナゾキシド、チフラミゾール、チフロレクス、チフルアドム、チフルカルビン、チホルミン、チフラク、チゲサイクリン、チゲモナム、チゲストール、チグロイジン、チラルゲニン(tilargenine)、チレタミン、チリジン、チリキノール、チリソロール、チルマコキシブ、チルミコシン、チルノプロフェン(tilnoprofen)、チロミソール、チロロン、チロゼピン、チルスプロスト、チルドロン酸(tiludonic acid)、チムコダル(timcodar)、チメフロン、チメガジン、チメロテム、チメピジウ
ム、チミペロン、チミルジン、チモベソンアセタート、チモフィブラート、チモロール、チモナシク、チモプラゾール、チナビノール、チナゾリン、テルニダゾール(timidazole)、チニスルプリド、チノフェドリン、チノリジン、チオカルリド、チオクロマロール、チオコナゾール、チオクチラート、チオダゾシン、チオドニウム、チオメルギン、チオメステロン、チオペリドン、チオピナート(tiopinate)、チオプロニン、チオプロパミン、チオスピロン、チオチジン、チオトロピウム、チオキサシン、チオキサマスト、チオキサプロフェン、チオキシダゾール、チオキソロン、チペントシン、チペピジン、チペトロピウム、チピファルニブ、チピンドール、チプラナビル、チプレダン、チプレノロール、チプリナスト、チプロピジル(tiprodil)、チプロスタニド、チプロチモド(tiportimod)、チクェシド、チキナミド、チキジウム、チラシジン、チラパザミン、チラトリコール、チリラザド、チロフィバン、チロプラミド(tiropramine)、チサルタン(tisartan)、チソカルシタート、チソクロミド、チソプリン、チソクォン、チバニダゾール、チビシクロビル、チビラピン、チキサジル、チキサノクス、チキソコルトール、チザブリン、チザニジン、チゾレミド、チゾプロール酸、トビシリン、トボリノン、トブラマイシン、トカミド(tocamide)、トカンフィル、トクラデシン、トコフェノキサート、トコフィブラート、トコフェルソラン(tocophersolan)、トドララジン、トフェナシン、トフェトリジン、トフィミラスト、トフィソリン、トフィソパム(tofisppam)、トラフェントリン、トラモロール、トラザミド、トルボキサン、トルブタミド、トルバポン(tolvapone)、トルシクラート、トルジムホス、トルファミド、トルフェナム酸、トルガビド、トリミドン、トリンダート、トリオジウム、トリプロロール、トルメソキシド、トルメチン(tometin)、トルナフテート、トルナペルシン、トルニダミン、トロコニウム、トロニジン、トロニウム、トロキサトン、トロキシクロリノール、トルパドール、トルペンタミド、トルペリゾン、トルピプラゾール、トルプロニン、トルプロパミド(tolpropamide)、トルピラミド、トルキンゾール、トルレスタット、トルテロジン、トルトラズリル、トルファゼパム、トルバプタン、トリカイニン、トメグロビル、トメルカスト、トモグルミド、トモキシプロール、トナベルサト、トナゾシン、トピルタミド、トピラマート、トピキサントロン(topixantrone)、トポテカン、トプリリジン、トプテロン、トキジン、トルバフィリン、トルセトラピブ、トルシタビン、トレミフェン、トリプリストン、トルセミド、トサゲスチン(tosagestin)、トシフェン、トスフロキサシン(tosufioxacin)、トスルル、トラベクテジン、トラボキソピン、トラカゾラート、トラデカミド、トラロニド、トラマドール、トラマゾリン、トランドラプリル、トランドラプリラト、トラネキサム酸、トラニラスト、トランスカイニド(transcamide)、トランテリニウム、トラニルシプロミン(tranycypromine)、トラペンカイン、トラピジル、トラボプロスト、トラキサノクス、トラキソプロジル、トラジチリン、トラジウム、トラゾドン、トラゾロプリド、トレベンゾミン、トレカドリン、トレセチリド、トレフェンタニル、トレルナリジン、トレロキシナート、トレンボロン、トレンゲストン、トレニジン、トレオスルファン、トレピブトン、トレピパム、トレピリウム、トレプロスチニル、トレプチラミン、テルキシン(terquisin)、トレスペリムス、トレストロン、トレチニウム、トレトカン酸(trethocanoic acid)、トレチノイン、トレチノイントコフェリル、トレトキノール、トリアセチン、トリアフンギン、トリアムシノロン、トリアムシノロンアセトニド、トリアムシノロンベネトニド、トリアムシノロンフレトニド、トリアンジピン、トリアムテレントリアジコン(triamternem triaziquone)、トリアゾラム、トリベンジロール、トリベノシド、トリブロムサラン、トリブゾン、トリカプリリン(tricaprilin)、トリセタミド(tricetamide)、トリクロルホン、トリクロルメチアジド、トリクロルメチン(trichlomethine)、トリシリビン、トリクラベンダゾール、トリクラセタモール、トリクラザート、トリクロビソニウム、トリクロカルバン、トリクロダゾール、トリクロフェノール、トリクロホス、トリクロフィリン、トリクロニド、トリクロサン、トリシクラモール、ト
リジヘキセチル、トリドルゴシル、トリエンチン、トリエチレンメラミン、トリフェナグレル、トリフェゾラク、
トリフロシン、トリフルバザム、トリフルミダート、トリフルオメプラジン(triflomeprazine)、トリフロペラジン(trifluperazine)、トリフルペリドール、トリフルプロマジン、トリフルイジン(trifluidine)、トリフルサール、トリホスミン(trifosmin)、トリゲボロール、トリヘキシフェニジル(trihexylpheidyl)、トリレチド、トリロスタン、トリマゾシン、トリメブチン、トリメカイン(trimecain)、トリメドキシム(trimedoxime)、トリメゲストン、トリメペリジン、トリメプラジン、トリメタジジン、トリメタドン(trimethadone)、トリメタミド、トリメタファン、トリメチジニウム、トリメトベンズアミド、トリメトプリム、トリメトジン、トリメトレキサート(trimetrexzate)、トリメキシリン、トリミプラミン、トリモプロスチル、トリモキサミン、トリオキシフェン、トリオキスサレン、トリパルミチン、トリパミド、トリパラノール、トリペレナミン、トリプラチン、トリプロリジン、トリプトレリン、トリトクァリン、トリキソラン、トリゾキシム、トロシミン、トロクロセン、トロデュスケミン、トロホスファミド、トログリタゾン、トロレアンドマイシン、トロマンタジン(tromanttadine)、トロパバザート、トロパンセリン、トロパプリド、トロパテピン、トロペンジリン、トロピカミド、トロピグリン(tropigline)、トロピリン、トロピセトロン、トロポジフェン(tropodifene)、トロキダゾール、トロスペクトマイシン、トロスピウム、トロバフロキサシン、トロビルジン、トロキサシタビン、トロキセルチン、トロキシピド、トロキソラミド、トロキソニウム、トロキシピロリウム、トルキシクリウム、トルキシピクリウム、トリパルサミド、ツボクラリン、ツブロゾール、ツカレソール、ツクラゼパム、ツラスロマイシン、ツロブテロール、ツロパファント、ツロステリド、ツバチジン、チバマート、タイロシン、チマゾリン(tymazolin)、チロパノエート、チロシン、チロトリシン、ウベニメクス、ユビデカレノン、ウビシンジン、ウフェナマート、ウフィプラゾール、ウルダゼパム、ウリフロキサシン、ウリプリスニル(uliprisnil)、ウメスピロン、ウンデシレン酸、ウノプロストン、ウペナジム、ウピドシン、ウラシル、ウラシルマスタード、ウラピジル、ウレデパ、ウレドホス、ウレフィブラート、ウルソジオール、ウルスルコール酸(urulcholic acid)、ウチバプリル、ウチバプリラト、バドカイン、バラシクロビル、バルコナゾール、バルデコキシブ、バルデタミド、バルジプロミド、バレタマート、バルガンシクロビル(vlaganiciclovir)、バリン、バルネムリン、バルノクタミド(vlanoctamide)、バロファン、バロマシクロビル、バルペリノール、バルプロエート、バルプロ酸(vlaproicacid)、バルプロミド、バルロセミド、バルルビシン(valrubicin)、バルサルタン、バロルシタビン(valorcitabine)、バルトラート、バミカミド、バンコマイシン、バンデタニブ、バネプリム、バニチオリド、バノキセリン、バニルジスルファミド、バピプロスト、バプレオチド、バルデナフィル(vardenfanil)、バレニクリン、バレスプラジブ、バタラニブ、バタニジピン、ベブフロキサシン、ベクロニウム、ベダクリジン、ベダプロフェン、ベラレソール、ベルナクリン、ベンラファキシン、ベンリチジン、ベラドリン(verodoline)、ベラリプリド、ベラパミル、ベラジド、ベリロパム、ベルルカスト、ベロフィリン、ベルセタミド、ベルテポルフィン、ベスナリノン、ベスチピタント、ベトラブチン、ビダラビン、ビガバトリン、ビラゾドン、ビルダグリプチン(vildaglipin)、ビロキサジン、ビンバルビタール、ビンブラスチン、ビンブルニン、ビンカミン、ビンカノール、ビンコホス、ビンコナート、ビンクリスチン、ビンデブルノール、ビンデシン、ビンピジン(vinpidine)、ビンフルニン、ビンホルミド(vinformide)、ビンホシルチン、ビングリシナート、ビンロイシノール、ビンロイロシン、ビンメガラート(vinmegallate)、ビノレルビン、ビンポセチン、ビンポリン、ビンロシジン、ビンチアモール、ビントペロール、ビントリプトール、ビニルビタール、ビンゾリジン、バイオマイシン、ビプロストール、ビクァリン、ビ
キジル、バージニアマイシン、ビリドフルビン、ビロキシム、ビスナジン、ビスナフィリン(visnafylline)、ボホピタント、ビグリボース、ボラゾシン、ボルプリスチン(volpristin)、ボリコナゾール、ボロゾール、ボキセルゴリド、キサリプロデン、キサモテロール、キサノメリン、キサノクス酸、キサンチノール、キサンチフィブラート(xantifibrate)、キサントシリン(xantocillin)、パルミチン酸キサントフィル、キセミロフィバン、キセナリピン、キセナゾ酸、キセンブシン、キセニペントン、キセンチオラート(xenothiorate)、キセニグロキサール、キセニヘキセン酸(xenylhexenicacid)、キセニトロピウム(xenylropium)、キシベノロール、キシボルノール、キシデカフルール、キシロバム、キシメラガトラン、キシモプロフェン、キシニダミン(ximidamine)、キシノミリン、キシパミド(sipamide)、キシプラノロール、キソルファノール、キシラミジン、キシラジン、キシロクマロール、キシロメタゾリン、キシロキセミン、ヨヒンビン酸、ザビシプリル、ザビシプリラト、ザコプリド、ザフィルルカスト、ザフレプチン、ザルシタビン、ザルデリド(zalderide)、ザレプロン、ザロスピロン、ザリチジン(zalitidine)、ザルトプロフェン、ザミフェナシン、ザナミビル、ザナペジル、ザンキレン、ザノテロン、ザピゾラム、ザプリナスト、ザルダベリン、ザテブラジン、ザトセトロン、ゼランドパム(zelandopam)、ゼナレスタット、ゼナゾシン(zenazocine)、ゼニプラチン、ゼパスチン、ゼラノール、ゼチドリン、ジダパミド、ジドメタシン、ジドブジン、ジフロシロン(zifrostilone)、ジランテル、ジラスコルブ、ジレウトン、ジルパテロール、ジメルジン、ジミドベン(zimiidoben)、ジンドトリン、ジンドキシフェン、ジンコナゾール(zinconazole)、ジノスタチン、ジンテロール、ジンビロキシム、ジペプロール、ジプラシドン(ziprsidone)、ゾカイノン、ゾフェノプリル、ゾフェノプリラト、ゾフィコナゾール、ゾラミン、ゾラサルタン、ゾラゼパム、ゾレンドロン酸(zolendronic acid)、ゾレンゼピン、ゾレルチン、ゾリミジン、ゾリプロフェン、ゾルミトリプタン、ゾロペロン、ゾルピデム、ゾメバザム、ゾメピラク、ゾメタピン、ゾナムパネル、ゾニクレゾール、ゾニポリド、ゾニサミド、ゾピクロン、ゾポルレスタット、ゾルバマイシン、ゾルビシン、ゾスキダル、ゾテピン、ゾチカソン(zoticasone)、ゾキサゾラミン、ズカプサイシン、ズクロミフェン、ズクロペンチキソール、ジロフラミン、およびこれらの組み合わせ。
本発明の例示的実施形態は、薬学的に活性な化合物の長期間の放出のための吸収が制御された薬学的製剤を含む。いくつかの実施形態において、上記放出が制御された投与形態は、固体の経口投与形態を嚥下するのに当たって困難を伴う患者に投与するために適した薬学的に活性な薬剤の経口投与のために製剤化される。さらなる実施形態において、上記吸収が制御された薬学的製剤は、錠剤、カプセル剤もしくは丸剤を嚥下するのにあたって困難を伴う患者で使用するために、受容可能な「軟らかい食品」とともに使用され得る。いくつかの実施形態において、上記吸収が制御された薬学的製剤は、上記薬学的に活性な化合物の時限式放出が望ましい経鼻胃管栄養チューブもしくは任意の他の「栄養チューブ」タイプの装置において、上記薬学的に活性な化合物を投与するために改変され得る。
8mm〜0.9mm、0.1mm〜0.2mm、0.1mm〜0.3mm、0.1mm〜0.4mm、0.1mm〜0.5mm、0.1mm〜0.6mm、0.1mm〜0.7mm、0.1mm〜0.8mm、0.2mm〜0.3mm、0.2mm〜0.4mm、0.2mm〜0.5mm、0.2mm〜0.6mm、0.2mm〜0.7mm、0.2mm〜0.8mm、0.3mm〜0.4mm、0.3mm〜0.5mm、0.3mm〜0.6mm、0.3mm〜0.7mm、0.3mm〜0.8mm、0.4mm〜0.5mm、0.4mm〜0.6mm、0.4mm〜0.7mm、0.4mm〜0.8mm、0.5mm〜0.6mm、0.5mm〜0.7mm、0.5mm〜0.8mm、0.6mm〜0.7mm、もしくは0.7mm〜0.8mmの範囲に及ぶ。
ここでn(i)は、特定の範囲の粒子直径を有する粒子の数であり、n(t)は、サンプル中の総粒子数である。図6において、例えば、n(t)=(6+15+16+10+3+2+1+5+1)=59であり、102〜207mmの粒子直径範囲を有する粒子のパーセンテージは、(6/59)×100%≒10.2%である。この計算は、粒子直径の範囲の各々について行われ得る。類似のセットの計算が、粒子直径の各範囲内の粒子のパーセンテージを決定するために、図7における粒子分布について行われ得る。
くとも約179μmであるが約240μm以下である粒子直径を有し;上記粒子のうちの約14%は、少なくとも約179μmであるが約302μm以下である粒子直径を有し;上記粒子のうちの約37%は、少なくとも約179μmであるが約364μm以下である粒子直径を有し;上記粒子のうちの約53%は、少なくとも約179μmであるが約426μm以下である粒子直径を有し;上記粒子のうちの約74%は、少なくとも約179μmであるが約488μm以下である粒子直径を有し;上記粒子のうちの約87%は、少なくとも約179μmであるが約550μm以下である粒子直径を有し;上記粒子のうちの約90%は、少なくとも約179μmであるが約612μm以下である粒子直径を有し;上記粒子のうちの約93%は、少なくとも約179μmであるが約674μm以下である粒子直径を有し;上記粒子のうちの約97%は、少なくとも約179μmであるが約736μm以下である粒子直径を有し;そして上記粒子のうちの少なくとも約98%は、少なくとも約179μmであるが約860μm以下である粒子直径を有する。
おいて、上記薬学的に活性な物質は、ナプロキセンナトリウム塩である。別の実施形態において、上記薬学的に活性な物質は、ナプロキセン遊離酸である。一実施形態において、上記吸収が制御された組成物は、ナプロキセンの経口投与に適合され、上記の長期効果と一緒に鎮痛に有効な血中レベルの迅速な達成を確実にするために十分な量のナプロキセンの即放性形態を含む。
1、約62:1、約63:1、約64:1、約65:1、約66:1、約67:1、約68:1、約69:1、約70:1、約71:1、約72:1、約73:1、約74:1、約75:1、約76:1、約77:1、約78:1、約79:1、約80:1、約81:1、約82:1、約83:1、約84:1、約85:1、約86:1、約87:1、約88:1、約89:1、約90:1、約91:1、約92:1、約93:1、約94:1、約95:1、約96:1、約97:1、約98:1、約99:1、約100:1、約101:1、約102:1、約103:1、約104:1、約105:1、約106:1、約107:1、約108:1、約109:1、約110:1、約111:1、約112:1、約113:1、約114:1、約115:1、約116:1、約117:1、約118:1、約119:1、約120:1、約121:1、約122:1、約123:1、約124:1、約125:1、約126:1、約127:1、約128:1、約129:1、約130:1、約131:1、約132:1、約133:1、約134:1、約135:1、約136:1、約137:1、約138:1、約139:1、約140:1、約141:1、約142:1、約143:1、約144:1、約145:1、約146:1、約147:1、約148:1、約149:1、約150:1、約151:1、約152:1、約153:1、約154:1、約155:1、約156:1、約157:1、約158:1、約159:1、約160:1、約161:1、約162:1、約163:1、約164:1、約165:1、約166:1、約167:1、約168:1、約169:1、約170:1、約171:1、約172:1、約173:1、約174:1、約175:1、約176:1、約177:1、約178:1、約179:1、約180:1、約181:1、約182:1、約183:1、約184:1、約185:1、約186:1、約187:1、約188:1、約189:1、約190:1、約191:1、約192:1、約193:1、約194:1、約195:1、約196:1、約197:1、約198:1、約199:1、もしくは約200:1。
において、上記水溶性ポリマーは、エチルセルロースである。
ましい実施形態において、上記ナプロキセン成分および結合ポリマー成分は、約6:1〜1:1の重量比において存在する。一実施形態において、上記ブレンドは、製粉機を使用して、適切なメッシュスクリーンに通過させられ得る。
ガムおよびこれらの組み合わせが挙げられる。
以下の実施例は、本発明の比較物(comparators)および実施形態、ならびにこれらの種々の使用の例示である。これらは、例示目的で示されるに過ぎず、本発明を限定するとして解釈されるべきでない。
Methocel(20g)およびナプロキセンナトリウム(44g)を、周囲温度において25RPMに設定したKitchenaidミキサー(Model KSM103)中で10分間にわたってブレンドした。
粒機)に移した。造粒溶液(Surelease K−L−7 19040 clear)を、20% 固形物を含むように希釈した。上記床を、スプレーを開始する前に5分間にわたって流動化した。被覆を適用している間中、床温度を30〜35℃に維持しながら、Sureleaseを5g/分の速度においてスプレーした。全ての造粒がし尽くされるまで、造粒を継続した。次いで、上記床を流動化しながら上記造粒物を40℃において2時間にわたって造粒機中に残しておいて、上記Sureleaseを硬化させた。
Methocel(56g)およびナプロキセンナトリウム(44g)を、周囲温度において25RPMに設定したKitchenaidミキサー(Model KLM109)中で10分間にわたってブレンドした。
Avocel(17g)およびナプロキセンナトリウム(53g)を、周囲温度において25RPMに設定したKitchenaidミキサー(Model KLM103)中で10分間にわたってブレンドした。
Prosolv HD90(25g)およびナプロキセンナトリウム(58.3g)を、周囲温度において25RPMに設定したKitchenaidミキサー(Model KLM103)中で10分間にわたってブレンドする。
Prosolv HD90(20g)およびナプロキセンナトリウム(58g)を、周囲温度において25RPMに設定したKitchenaidミキサー(Model KLM103)中で10分間にわたってブレンドする。
添付の図面は、米国薬局方XXIIバスケット法という方法によって、2種の参照ナプロキセン製剤と比較して本発明に従うナプロキセン製剤についての、リン酸緩衝液(pH7.2)中および75r.p.m.で試験した場合に放出されたナプロキセン%の、時間(時間)に対するグラフである。上記ナプロキセンナトリウムを、331nmでの紫外線分光光度計を使用して定量的に決定した。
(項1)
粒状組成物であって、
(a)生物学的に活性なコアであって、該生物学的に活性なコアは、薬学的に活性な物質および1種以上の薬物結合ポリマーのセットを含み、ここで該薬学的に活性な物質は、1種以上の薬物結合ポリマーの該セットと可逆的に会合(association)した状態である、生物学的に活性なコア;ならびに
(b)被覆であって、該被覆は、膜形成ポリマーを含み、該膜形成ポリマーは、該コアを取り囲んでおり、ここで該薬学的に活性な物質は、薬学的に活性な化合物、該薬学的に活性な化合物の薬学的に受容可能な塩もしくはこれらの組み合わせを含む、被覆、
を含む、粒状組成物。
(項2)
粒状組成物であって、
(a)1種以上の薬物結合ポリマーのセットを含む、生物学的に不活性なコア;および
(b)被覆であって、該被覆は、膜形成ポリマーを含み、該膜形成ポリマーは、該コアを取り囲んでいる、被覆、
を含む、粒状組成物。
(項3)
1種以上の薬物結合ポリマーの前記セットは、エチルセルロース、セルロースアセテート、セルロースプロピオネート(低分子量、中間分子量、もしくは高分子量)、セルロースアセテートプロピオネート、セルロースアセテートブチレート、セルロースアセテートフタレート、セルローストリアセテート、ポリ(メチルメタクリレート)、ポリ(エチルメタクリレート)、ポリ(ブチルメタクリレート)、ポリ(イソブチルメタクリレート)、ポリ(ヘキシルメタクリレート)、ポリ(イソデシルメタクリレート)、ポリ(ラウリルメタクリレート)、ポリ(フェニルメタクリレート)、ポリ(メチルアクリレート)、ポリ(イソプロピルアクリレート)、ポリ(イソブチルアクリレート)、ポリ(オクタデシルアクリレート)、ポリ(エチレン)、ポリ(エチレン)低密度、ポリ(エチレン)高密度、ポリ(プロピレン)、ポリ(エチレンオキシド)、ポリ(エチレンテレフタレート)、ポリ(ビニルイソブチルエーテル)、ポリ(ビニルアセテート)、ポリ(ビニルクロリド)もしくはポリウレタンおよびこれらの組み合わせからなる群より選択される、上記項1に記載の粒状組成物。
(項4)
前記薬学的に活性な物質および1種以上の薬物結合ポリマーの前記セットは、それぞれ、約20:1〜約1:2の重量比において前記生物学的に活性なコアに存在する、上記項1に記載の粒状組成物。
(項5)
前記薬学的に活性な物質と1種以上の薬物結合ポリマーの前記セットとの間の前記可逆的会合は、化学結合、イオン結合、錯体形成、ファンデルワールス相互作用、水素結合、もしくはこれらの組み合わせを含む、上記項1に記載の粒状組成物。
(項6)
1種以上の薬物結合ポリマーの前記セットのうちの少なくとも1種は、水不溶性である、上記項1に記載の粒状組成物。
(項7)
1種以上のポリマーの前記セットのうちの少なくとも1種は、水溶性である、上記項1に記載の粒状組成物。
(項8)
前記被覆は、薬物放出を遅らせ得る水不溶性の透水性ポリマーを含む、上記項1に記載の粒状組成物。
(項9)
前記生物学的に活性なコアは、粉末を含み、前記粉末は、1種以上の薬物結合ポリマーの前記セットの粒子と混合された前記薬学的に活性な物質の粒子を含み、前記被覆は、水不溶性の透水性ポリマーを含む、上記項1に記載の粒状組成物。
(項10)
前記生物学的に活性なコアは、粉末を含み、該粉末は、1種以上の薬物結合ポリマーの前記セットの粒子と混合された前記薬学的に活性な物質の粒子を含み、ここで1種以上の薬物結合ポリマーの該セットは、少なくとも1種の薬学的に受容可能な水不溶性ポリマーを含み、前記被覆は、水不溶性の透水性ポリマーを含む、上記項1に記載の粒状組成物。
(項11)
上記項1に記載の粒状組成物を作製する方法であって、該方法は、
(a)粉末をブレンドして、均質な粉末化薬物−ポリマーブレンドを形成する工程であって、該粉末は、薬学的に活性な物質の粒子および1種以上のポリマーのセットの粒子を含む、工程;
(b)該均質な粉末化薬物−ポリマーブレンドの一部を成形して、中心コアを形成する工程;ならびに
(c)ポリマー結合溶液を該中心コアに適用して、該中心コア上に層状構造を形成する工程であって、ここで該薬学的に活性な物質は、薬学的に活性な化合物、該薬学的に活性な化合物の薬学的に受容可能な塩もしくはこれらの組み合わせを含む、工程、
を包含する、方法。
(項12)
上記項2に記載の粒状組成物を作製する方法であって、該方法は、
(a)粉末をブレンドして、均質な粉末化薬物−ポリマーブレンドを形成する工程であって、該粉末は、1種以上のポリマーのセットの粒子を含む、工程;
(b)該均質な粉末化薬物−ポリマーブレンドの一部を成形して、中心不活性コアを形成する工程;ならびに
(c)ポリマー結合溶液を該中心不活性コアに適用して、該中心コア上に層状構造を形成する工程、
を包含する、方法。
(項13)
上記項1に記載の粒状組成物を含み、米国薬局方XXIIに従うタイプ1溶解バスケット装置においてリン酸緩衝液(pH7.2)中および75r.p.m.で測定した場合に、以下の溶解パターンに相当する溶解速度を有する、放出が制御された薬学的組成物:
(a)薬学的に活性な化学物質の全体のうちの15〜30%が、該装置において0.5時間後の測定時に放出されている;
(b)薬学的に活性な化学物質の全体のうちの25〜60%が、該装置において1時間後の測定時に放出されている;および
(c)薬学的に活性な化学物質の全体のうちの65%以上が、該装置において4時間後の測定時に放出されている。
(項14)
前記組成物は、1日1回の固体で放出が制御された経口投与形態である、上記項13に記載の放出が制御された薬学的組成物。
(項15)
前記組成物は、1日2回の固体で放出が制御された経口投与形態である、上記項13に記載の放出が制御された薬学的組成物。
(項16)
薬学的に活性な物質の単一用量の送達を1日1回へと、もしくは被験体への該用量の投与から1日を超えて長期化するための方法であって、該方法は、
(a)粉末をブレンドして、均質な粉末薬物−ポリマーブレンドを形成する工程であって、該粉末は、該薬学的に活性な物質の粒子および1種以上のポリマーのセットの粒子を含み、
ここで該均質な粉末薬物−ポリマーブレンドは、該薬学的に活性な物質を1種以上の薬物結合ポリマーの該セットと可逆的に会合した状態において含み、
該薬学的に活性な物質は、薬学的に活性な化合物、該薬学的に活性な化合物の薬学的に受容可能な塩もしくはこれらの組み合わせを含む、工程;
(b)該均質な粉末薬物−ポリマーブレンドの一部を成形して、中心コアを形成する工程;ならびに
(c)ポリマー結合溶液を該中心コアに適用して、該中心コア上に層状構造を形成して、放出が制御された薬学的組成物を形成する工程であって、
ここで該放出が制御された薬学的組成物は、該薬学的に活性な物質を該被験体に、該薬学的組成物の単一用量の投与から、少なくとも1日以上の日数にわたって送達する,工程を包含する、方法。
(項17)
前記粒状組成物は、約100μm〜約900μmの平均直径を有する微粒子/微小粒状物質を含む、上記項1〜10のいずれか1項に記載の粒状組成物。
(項18)
前記粒状組成物は、以下からなる群より選択される平均直径を有する微粒子/微小粒状物質を含む、上記項17に記載の粒状組成物: 100μm〜約150μm;約150μm〜約200μm;約200μm〜約250μm;約250μm〜約300μm;約300μm〜約350μm;約350μm〜約400μm;約400μm〜約450μm;約450μm〜約500μm;約500μm〜約550μm;約550μm〜約600μm;約600μm〜約650μm;約650μm〜約700μm;約700μm〜約750μm;約750μm〜約800μm;約800μm〜約850μm;約850μm〜約900μm;約150μm〜約200μm;約200μm〜約250μm;約250μm〜約300μm;約300μm〜約350μm;約350μm〜約400μm;約400μm〜約450μm;約450μm〜約500μm;約500μm〜約550μm;約550μm〜約600μm;約600μm〜約650μm;約650μm〜約700μm;約700μm〜約750μm;約750μm〜約800μm;約800μm〜約850μm;約200μm〜約250μm;約250μm〜約300μm;約300μm〜約350μm;約350μm〜約400μm;約400μm〜約450μm;約450μm〜約500μm;約500μm〜約550μm;約550μm〜約600μm;約600μm〜約650μm;約650μm〜約700μm;約700μm〜約750μm;約750μm〜約800μm;約250μm〜約300μm;約300μm〜約350μm;約350μm〜約400μm;約400μm〜約450μm;約450μm〜約500μm;約500μm〜約550μm;約550μm〜約600μm;約600μm〜約650μm;約650μm〜約700μm;約700μm〜約750μm;約300μm〜約350μm;〜約350μm〜約400μm;〜約400μm〜約450μm;〜約450μm〜約500μm;〜約350μm〜約400μm;〜約400μm〜約450μm;〜約450μm〜約500μmおよびこれらの組み合わせ。
(項19)
薬学的製剤であって、カプセルに充填されたかもしくは圧縮されて錠剤にされた上記項1〜10、17、および18のいずれか1項に記載の粒状組成物を含む、薬学的製剤。
(項20)
前記錠剤は、任意の水性媒体中に迅速に溶解して、前記粒状組成物の微小粒状物質を放出する、上記項19に記載の薬学的製剤。
(項21)
前記カプセルは、任意の水性媒体中に迅速に溶解して、前記粒状組成物の微小粒状物質を放出する、上記項19に記載の薬学的製剤。
(項22)
前記薬学的に活性な物質は、前記微小粒状物質単独の放出プロフィールに実質的に同じ/同一である放出プロフィールを有する制御された様式において放出される、上記項18〜21のいずれか1項に記載の薬学的製剤。
(項23)
前記薬学的製剤は、カプセルに充填された前記粒状組成物を含む、上記項18〜22のいずれか1項に記載の薬学的製剤。
(項23)
前記薬学的製剤は、圧縮されて錠剤にされた前記粒状組成物を含む、上記項18〜22のいずれか1項に記載の薬学的製剤。
(項24)
前記粒状組成物は、以下からなる群より選択される粒度分布を有する、上記項1〜10、17および18のいずれかに記載の組成物:前記粒子のうちの約60%は、約1267μm以下の粒子直径を有する;粒子のうちの58%は、約1055μm以下の粒子直径を有する;粒子のうちの約53%は、約949μm以下の粒子直径を有する;粒子のうちの約52%は、約737μm以下の粒子直径を有する;粒子のうちの約50%は、約631μm以下の粒子直径を有する;粒子のうちの約47%は、約525μm以下の粒子直径を有する;粒子のうちの約37%は、約419μm以下の粒子直径を有する;粒子のうちの約21%は、約313μm以下の粒子直径を有する;約および粒子のうちの6%は、約207μm以下の粒子直径を有する。
(項25)
前記粒状組成物は、以下からなる群より選択される粒度分布を有する、上記項1〜10、17および18のいずれかに記載の組成物:前記粒子のうちの約80%は、約860μm以下の直径を有する;粒子のうちの約77%は、約798μm以下の粒子直径を有する;粒子のうちの約75%は、約736μm以下の粒子直径を有する;粒子のうちの約69%は、約674μm以下の粒子直径を有する;粒子のうちの約65%は、約612μm以下の粒子直径を有する;粒子のうちの約61%は、約550μm以下の粒子直径を有する;粒子のうちの約52%は、約488μm以下の粒子直径を有する;粒子のうちの約37%は、約426μm以下の粒子直径を有する;粒子のうちの約26%は、約364μm以下の粒子直径を有する;粒子のうちの約10%は、約302μm以下の粒子直径を有する;約および粒子のうちの5%は、約240μm以下の粒子直径を有する。
Claims (17)
- 粒状組成物であって:
(a)生物学的に活性なコアであって、該生物学的に活性なコアは、以下:
(i)ナプロキセン、該ナプロキセンの薬学的に受容可能な塩、もしくはこれらの組み合わせ、および
(ii)ケイ化高密度微結晶セルロースを含む薬物結合ポリマーであって、ここで、該ナプロキセン、該ナプロキセンの薬学的に受容可能な塩、もしくはこれらの組み合わせは、該薬物結合ポリマーと可逆的に会合した状態でそして約20:1〜約1:2のそれとの重量比である、薬物結合ポリマー
を含む、生物学的に活性なコア;ならびに
(b)被覆であって、該被覆は、膜形成ポリマーを含み、該膜形成ポリマーは、エチルセルロースを含みそして該生物学的に活性なコアを取り囲む、被覆
を含み、ここで、該粒状組成物は、約100μm〜約900μmの平均直径を有する微粒子/微小粒状物質を含み;
ここで、該粒状組成物は、米国薬局方XXIIに従うタイプ1溶解バスケット装置においてリン酸緩衝液(pH7.2)中および75r.p.m.で測定した場合に、以下の溶解パターンに相当する溶解速度を有する、粒状組成物:
(c)該ナプロキセン、該ナプロキセンの薬学的に受容可能な塩、もしくはこれらの組み合わせの合計量のうちの15〜50%が、該装置において0.5時間後の測定時に放出されている;
(d)該ナプロキセン、該ナプロキセンの薬学的に受容可能な塩、もしくはこれらの組み合わせの合計量のうちの25〜75%が、該装置において1時間後の測定時に放出されている;および
(e)該ナプロキセン、該ナプロキセンの薬学的に受容可能な塩、もしくはこれらの組み合わせの合計量のうちの65%以上が、該装置において4時間後の測定時に放出されている。 - 粒状組成物であって:
(a)生物学的に活性なコアであって、該生物学的に活性なコアは、以下:
(i)ナプロキセン、該ナプロキセンの薬学的に受容可能な塩、もしくはこれらの組み合わせ、および
(ii)ケイ化高密度微結晶セルロースからなる薬物結合ポリマーであって、ここで、該ナプロキセン、該ナプロキセンの薬学的に受容可能な塩、もしくはこれらの組み合わせは、該薬物結合ポリマーと可逆的に会合した状態でそして約20:1〜約1:2のそれとの重量比である、薬物結合ポリマー
を含む、生物学的に活性なコア;ならびに
(b)被覆であって、該被覆は、膜形成ポリマーを含み、該膜形成ポリマーは、エチルセルロースを含みそして該生物学的に活性なコアを取り囲む、被覆
を含み、ここで、該粒状組成物は、約100μm〜約900μmの平均直径を有する微粒子/微小粒状物質を含み;
ここで、該粒状組成物は、米国薬局方XXIIに従うタイプ1溶解バスケット装置においてリン酸緩衝液(pH7.2)中および75r.p.m.で測定した場合に、以下の溶解パターンに相当する溶解速度を有する、粒状組成物:
(c)該ナプロキセン、該ナプロキセンの薬学的に受容可能な塩、もしくはこれらの組み合わせの合計量のうちの15〜50%が、該装置において0.5時間後の測定時に放出されている;
(d)該ナプロキセン、該ナプロキセンの薬学的に受容可能な塩、もしくはこれらの組み合わせの合計量のうちの25〜75%が、該装置において1時間後の測定時に放出されている;および
(e)該ナプロキセン、該ナプロキセンの薬学的に受容可能な塩、もしくはこれらの組み合わせの合計量のうちの65%以上が、該装置において4時間後の測定時に放出されている。 - 粒状組成物であって:
(a)生物学的に活性なコアであって、該生物学的に活性なコアは、以下:
(i)ナプロキセン、該ナプロキセンの薬学的に受容可能な塩、もしくはこれらの組み合わせ、および
(ii)ケイ化高密度微結晶セルロースであって、ここで、該ナプロキセン、該ナプロキセンの薬学的に受容可能な塩、もしくはこれらの組み合わせは、該ケイ化高密度微結晶セルロースと可逆的に会合した状態でそして約20:1〜約1:2のそれとの重量比である、ケイ化高密度微結晶セルロース
からなる、生物学的に活性なコア;ならびに
(b)被覆であって、該被覆は、膜形成ポリマーを含み、該膜形成ポリマーは、エチルセルロースを含みそして該生物学的に活性なコアを取り囲む、被覆
を含み、ここで、該粒状組成物は、約100μm〜約900μmの平均直径を有する微粒子/微小粒状物質を含み;
ここで、該粒状組成物は、米国薬局方XXIIに従うタイプ1溶解バスケット装置においてリン酸緩衝液(pH7.2)中および75r.p.m.で測定した場合に、以下の溶解パターンに相当する溶解速度を有する、粒状組成物:
(c)該ナプロキセン、該ナプロキセンの薬学的に受容可能な塩、もしくはこれらの組み合わせの合計量のうちの15〜50%が、該装置において0.5時間後の測定時に放出されている;
(d)該ナプロキセン、該ナプロキセンの薬学的に受容可能な塩、もしくはこれらの組み合わせの合計量のうちの25〜75%が、該装置において1時間後の測定時に放出されている;および
(e)該ナプロキセン、該ナプロキセンの薬学的に受容可能な塩、もしくはこれらの組み合わせの合計量のうちの65%以上が、該装置において4時間後の測定時に放出されている。 - 前記生物学的に活性なコアがさらに、セルロースアセテート、セルロースプロピオネート、セルロースアセテートプロピオネート、セルロースアセテートブチレート、セルロースアセテートフタレート、セルローストリアセテート、ポリ(メチルメタクリレート)、ポリ(エチルメタクリレート)、ポリ(ブチルメタクリレート)、ポリ(イソブチルメタクリレート)、ポリ(ヘキシルメタクリレート)、ポリ(イソデシルメタクリレート)、ポリ(ラウリルメタクリレート)、ポリ(フェニルメタクリレート)、ポリ(メチルアクリレート)、ポリ(イソプロピルアクリレート)、ポリ(イソブチルアクリレート)、ポリ(オクタデシルアクリレート)、ポリ(エチレン)、ポリ(エチレン)低密度、ポリ(エチレン)高密度、ポリ(プロピレン)、ポリ(エチレンオキシド)、ポリ(エチレンテレフタレート)、ポリ(ビニルイソブチルエーテル)、ポリ(ビニルアセテート)、ポリ(ビニルクロリド)もしくはポリウレタンおよびこれらの組み合わせからなる群から選択される1種以上の薬物結合ポリマーのセットを含む、請求項1に記載の粒状組成物。
- 前記ナプロキセン、前記ナプロキセンの薬学的に受容可能な塩もしくはこれらの組み合わせと前記薬物結合ポリマーとの間の前記可逆的会合は、化学結合、イオン結合、錯体形成、ファンデルワールス相互作用、水素結合、もしくはこれらの組み合わせを含む、請求項1に記載の粒状組成物。
- 前記1種以上の薬物結合ポリマーのセットのうちの少なくとも1種が水不溶性である、請求項4に記載の粒状組成物。
- 前記1種以上の薬物結合ポリマーのセットのうちの少なくとも1種が水溶性である、請求項4に記載の粒状組成物。
- 前記被覆は、薬物放出を遅らせ得る水不溶性の透水性ポリマーを含む、請求項4に記載の粒状組成物。
- 前記生物学的に活性なコアは、粉末を含み、該粉末は、前記薬物結合ポリマーの粒子と混合された前記ナプロキセン、前記ナプロキセンの薬学的に受容可能な塩もしくはこれらの組み合わせの粒子を含む、請求項1および2のいずれか1項に記載の粒状組成物。
- 前記生物学的に活性なコアは、粉末を含み、該粉末は、前記1種以上の薬物結合ポリマーのセットの粒子と混合された前記ナプロキセン、前記ナプロキセンの薬学的に受容可能な塩もしくはこれらの組み合わせの粒子を含み、ここで、該1種以上の薬物結合ポリマーのセットが、少なくとも1種の薬学的に受容可能な水不溶性ポリマーを含む、請求項4に記載の粒状組成物。
- 前記組成物は、1日1回の固体で放出が制御された経口投与形態である、請求項1、2、および3のいずれか1項に記載の粒状組成物。
- 前記組成物は、1日2回の固体で放出が制御された経口投与形態である、請求項1、2、および3のいずれか1項に記載の粒状組成物。
- 前記粒状組成物は、以下からなる群より選択される平均直径を有する微粒子/微小粒状物質を含む、請求項1、2、および3のいずれか1項に記載の粒状組成物:100μm〜約150μm;約150μm〜約200μm;約200μm〜約250μm;約250μm〜約300μm;約300μm〜約350μm;約350μm〜約400μm;約400μm〜約450μm;約450μm〜約500μm;約500μm〜約550μm;約550μm〜約600μm;約600μm〜約650μm;約650μm〜約700μm;約700μm〜約750μm;約750μm〜約800μm;約800μm〜約850μm;約850μm〜約900μm;約150μm〜約200μm;約200μm〜約250μm;約250μm〜約300μm;約300μm〜約350μm;約350μm〜約400μm;約400μm〜約450μm;約450μm〜約500μm;約500μm〜約550μm;約550μm〜約600μm;約600μm〜約650μm;約650μm〜約700μm;約700μm〜約750μm;約750μm〜約800μm;約800μm〜約850μm;約200μm〜約250μm;約250μm〜約300μm;約300μm〜約350μm;約350μm〜約400μm;約400μm〜約450μm;約450μm〜約500μm;約500μm〜約550μm;約550μm〜約600μm;約600μm〜約650μm;約650μm〜約700μm;約700μm〜約750μm;約750μm〜約800μm;約250μm〜約300μm;約300μm〜約350μm;約350μm〜約400μm;約400μm〜約450μm;約450μm〜約500μm;約500μm〜約550μm;約550μm〜約600μm;約600μm〜約650μm;約650μm〜約700μm;約700μm〜約750μm;約300μm〜約350μm;〜約350μm〜約400μm;〜約400μm〜約450μm;〜約450μm〜約500μm;〜約350μm〜約400μm;〜約400μm〜約450μm;〜約450μm〜約500μmおよびこれらの組み合わせ。
- 薬学的製剤であって、該薬学的製剤は、カプセルに充填されたかまたは圧縮されて錠剤にされた、請求項1、2および3のいずれか1項に記載の粒状組成物を含む、薬学的製剤。
- 前記粒状組成物は、以下からなる群より選択される粒度分布を有する、請求項1、2および3のいずれか1項に記載の組成物:
粒子のうちの約60%は、約1267μm以下の粒子直径を有する;粒子のうちの58%は、約1055μm以下の粒子直径を有する;粒子のうちの約53%は、約949μm以下の粒子直径を有する;粒子のうちの約52%は、約737μm以下の粒子直径を有する;粒子のうちの約50%は、約631μm以下の粒子直径を有する;粒子のうちの約47%は、約525μm以下の粒子直径を有する;粒子のうちの約37%は、約419μm以下の粒子直径を有する;粒子のうちの約21%は、約313μm以下の粒子直径を有する;および粒子のうちの約6%は、約207μm以下の粒子直径を有する。 - 前記粒状組成物は、以下からなる群より選択される粒度分布を有する、請求項1、2および3のいずれか1項に記載の組成物:
前記粒子のうちの約80%は、約860μm以下の直径を有する;粒子のうちの約77%は、約798μm以下の粒子直径を有する;粒子のうちの約75%は、約736μm以下の粒子直径を有する;粒子のうちの約69%は、約674μm以下の粒子直径を有する;粒子のうちの約65%は、約612μm以下の粒子直径を有する;粒子のうちの約61%は、約550μm以下の粒子直径を有する;粒子のうちの約52%は、約488μm以下の粒子直径を有する;粒子のうちの約37%は、約426μm以下の粒子直径を有する;粒子のうちの約26%は、約364μm以下の粒子直径を有する;粒子のうちの約10%は、約302μm以下の粒子直径を有する;および粒子のうちの約5%は、約240μm以下の粒子直径を有する。 - 前記膜形成ポリマーの溶液を15g/分の速度においてそして20〜25℃でスプレーすることにより前記被覆が生じる、請求項1、2および3のいずれか1項に記載の組成物。
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Families Citing this family (24)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US8445018B2 (en) | 2006-09-15 | 2013-05-21 | Cima Labs Inc. | Abuse resistant drug formulation |
EP3646870A1 (en) | 2009-07-22 | 2020-05-06 | Puretech Health LLC | Methods and compositions for treatment of disorders ameliorated by muscarinic receptor activation |
US10265311B2 (en) | 2009-07-22 | 2019-04-23 | PureTech Health LLC | Methods and compositions for treatment of disorders ameliorated by muscarinic receptor activation |
JP2014516080A (ja) | 2011-06-08 | 2014-07-07 | エスティーアイ ファーマ, エルエルシー | 一日一回の投与のための吸収が制御された水溶性の薬学的に活性な有機化合物製剤 |
AR096628A1 (es) | 2013-06-17 | 2016-01-20 | Raptor Pharmaceuticals Inc | Formulación en perlas de cisteamina de liberación retardada y métodos de preparación y uso de ella |
US9452181B2 (en) | 2013-07-22 | 2016-09-27 | Duchesnay Inc. | Composition for the management of nausea and vomiting |
PT3024466T (pt) | 2013-07-22 | 2018-07-13 | Duchesnay Inc | Composição para a gestão de náuseas e vómitos |
BR112017009876A2 (pt) | 2014-11-14 | 2017-12-19 | Gemphire Therapeutics Inc | processos e intermediários para a preparação de éteres de dialcano terminados em ácido alfa,ômega-dicarboxílico |
WO2017055935A1 (en) * | 2015-09-30 | 2017-04-06 | Symed Labs Limited | Amorphous co-precipitates of flibanserin |
US10143665B2 (en) | 2015-11-17 | 2018-12-04 | Horizon Orphan Llc | Methods for storing cysteamine formulations and related methods of treatment |
CN106866546A (zh) * | 2015-12-10 | 2017-06-20 | 常州爱诺新睿医药技术有限公司 | 氟班色林或其药学上可接受的盐与药用辅料的固体分散体及其制备方法 |
WO2018047002A1 (en) * | 2016-09-12 | 2018-03-15 | St Ip Holding Ag | Formulations of 4-methyl-5-(pyrazin-2-yl)-3h-1.2-dithiole-3-thione, taste-modified formulations, and methods of making and using same |
EP3509642A1 (en) | 2016-09-12 | 2019-07-17 | ST IP Holding AG | Formulations of 4-methyl-5-(pyrazin-2-yl)-3h-1, 2-dithiole-3-thione, and methods of making and using same |
WO2018047013A1 (en) * | 2016-09-12 | 2018-03-15 | St Ip Holding Ag | Formulations of 4-methyl-5-(pyrazin-2-yl)-3h-1, 2-dithiole-3-thione, and methods of making and using same |
JP2019533008A (ja) | 2016-09-12 | 2019-11-14 | エスティー アイピー ホールディング エージー | 4−メチル−5−(ピラジン−2−イル)−3h−1,2−ジチオール−3−チオンの処方物、味覚修飾処方物、ならびにそれらの製造方法及び使用方法 |
LT3519394T (lt) * | 2016-09-27 | 2020-09-25 | Bayer Pharma Aktiengesellschaft | Kalkobutrolio modifikacijos kristalinės formos gavimo būdas |
US11202760B2 (en) | 2016-09-30 | 2021-12-21 | Xenamed Corp. | Compositions of midodrine and methods of using the same |
TW201902471A (zh) * | 2017-04-18 | 2019-01-16 | 美商珍費爾醫療公司 | 賈卡賓尼(gemcabene)、其醫藥上可接受之鹽、彼等之組成物及使用彼等之方法 |
NZ773719A (en) | 2018-09-28 | 2022-07-29 | Karuna Therapeutics Inc | Compositions and methods for treating disorders ameliorated by muscarinic receptor activation |
US20210022994A1 (en) * | 2019-07-22 | 2021-01-28 | Lupin Holdings, B.V. | Sustained release trepostinil-compound microparticle compositions |
MX2022011196A (es) * | 2020-03-09 | 2022-09-19 | Sushma Paul Berlia | Formulaciones de liberacion controlada que comprenden drotaverina o una sal de la misma. |
US11135220B1 (en) | 2020-04-08 | 2021-10-05 | St Ip Holding Ag | Methods of treating viral infections with formulated compositions comprising 4-methyl-5-(pyrazin-2-yl)-3H-1,2-dithiole-3-thione |
KR20220048341A (ko) * | 2020-10-12 | 2022-04-19 | 뉴지랩테라퓨틱스 주식회사 | 나파모스타트 또는 이의 약제학적으로 허용가능한 염을 함유하는 방출 조절 제형 및 이의 제조방법 |
EP4304564A1 (en) * | 2021-03-09 | 2024-01-17 | Ensysce Biosciences, Inc. | Modified release compositions of nafamostat and methods of using same |
Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2014516080A (ja) * | 2011-06-08 | 2014-07-07 | エスティーアイ ファーマ, エルエルシー | 一日一回の投与のための吸収が制御された水溶性の薬学的に活性な有機化合物製剤 |
Family Cites Families (31)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS521867A (en) | 1975-06-24 | 1977-01-08 | Tonichi Kotsu Consultant:Kk | Rotary vertical garrage |
JPS6327424A (ja) * | 1986-07-17 | 1988-02-05 | Shionogi & Co Ltd | 徐放性製剤およびその製造法 |
GB8618811D0 (en) | 1986-08-01 | 1986-09-10 | Approved Prescription Services | Sustained release ibuprofen formulation |
GB8724763D0 (en) * | 1987-10-22 | 1987-11-25 | Aps Research Ltd | Sustained-release formulations |
US4971805A (en) * | 1987-12-23 | 1990-11-20 | Teysan Pharmaceuticals Co., Ltd. | Slow-releasing granules and long acting mixed granules comprising the same |
NZ247044A (en) * | 1989-06-23 | 1997-04-24 | Syntex Usa Inc Substituted For | Use of ranolazine and related piperazine derivatives to treat tissue affected by muscle and neuronal damage, including transplant tissue |
IE66933B1 (en) * | 1990-01-15 | 1996-02-07 | Elan Corp Plc | Controlled absorption naproxen formulation for once-daily administration |
US5431922A (en) | 1991-03-05 | 1995-07-11 | Bristol-Myers Squibb Company | Method for administration of buspirone |
KR100221695B1 (ko) | 1991-08-12 | 1999-09-15 | 그린 마틴, 브라이언 쥐 테슬리 | 약학적 구상 제형 |
US5376384A (en) * | 1992-12-23 | 1994-12-27 | Kinaform Technology, Inc. | Delayed, sustained-release pharmaceutical preparation |
DK66493D0 (da) | 1993-06-08 | 1993-06-08 | Ferring A S | Praeparater, isaer til brug ved behandling af inflammatoriske tarmsygdomme eller til at opnaa forbedret saarheling |
US5558879A (en) * | 1995-04-28 | 1996-09-24 | Andrx Pharmaceuticals, Inc. | Controlled release formulation for water soluble drugs in which a passageway is formed in situ |
SE9600070D0 (sv) * | 1996-01-08 | 1996-01-08 | Astra Ab | New oral pharmaceutical dosage forms |
AU6283299A (en) * | 1998-10-01 | 2000-04-17 | Elan Pharma International Limited | Controlled release nanoparticulate compositions |
US6528090B2 (en) | 1998-12-18 | 2003-03-04 | Abbott Laboratories | Controlled release formulation of divalproex sodium |
FR2796790B1 (fr) | 1999-07-23 | 2002-11-29 | Sagem | Procedes de transmission et de diffusion de paquets de donnees et recepteurs pour la mise en oeuvre des procedes |
DK1411900T4 (da) | 2001-06-01 | 2014-01-27 | Pozen Inc | Farmaceutiske sammensætninger til den koordinerede frigørelse af NSAIDs |
US7101573B2 (en) * | 2001-09-28 | 2006-09-05 | Mcneil-Pcc, Inc. | Simethicone solid oral dosage form |
EP1572164A2 (en) | 2002-12-18 | 2005-09-14 | Pain Therapeutics, Inc. | Oral dosage forms with therapeutically active agents in controlled release cores and immediate release gelatin capsule coats |
CA2520321A1 (en) * | 2003-04-04 | 2004-10-14 | Pharmacia Corporation | Oral extended release compressed tablets of multiparticulates |
US20040219210A1 (en) * | 2003-05-01 | 2004-11-04 | Jian-Hwa Guo | Controlled release solid dosage nifedipine formulations |
SI21638A (sl) * | 2003-11-12 | 2005-06-30 | LEK farmacevtska družba d.d. | Farmacevtska oblika z nadzorovanim sproščanjem ketoprofena |
US9161918B2 (en) * | 2005-05-02 | 2015-10-20 | Adare Pharmaceuticals, Inc. | Timed, pulsatile release systems |
JP4936420B2 (ja) * | 2005-08-02 | 2012-05-23 | 塩野義製薬株式会社 | 徐放性顆粒剤 |
WO2007078895A2 (en) * | 2005-12-30 | 2007-07-12 | Biovail Laboratories International S.R.L. | Modified release formulations of tramadol and uses thereof |
US20070160667A1 (en) * | 2006-01-11 | 2007-07-12 | Nava Shterman | Controlled release formulation of divalproex sodium |
WO2008157240A1 (en) * | 2007-06-13 | 2008-12-24 | Auspex Pharmaceuticals, Inc. | Substituted piperazines |
US20100008986A1 (en) * | 2008-07-14 | 2010-01-14 | Glenmark Generics, Ltd. | Pharmaceutical compositions comprising sumatriptan and naproxen |
WO2010009432A1 (en) * | 2008-07-17 | 2010-01-21 | Horizon Therapeutics, Inc. | Nsaid dose unit formulations with h2-receptor antagonists and methods of use |
WO2010014502A1 (en) * | 2008-07-31 | 2010-02-04 | Aptapharma, Inc. | Functionally coated breakable tablets |
US20100305163A1 (en) * | 2009-05-20 | 2010-12-02 | Pramod Dattatray Yedurkar | Pharmaceutical formulations comprising nsaid and proton pump inhibitor drugs |
-
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Patent Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2014516080A (ja) * | 2011-06-08 | 2014-07-07 | エスティーアイ ファーマ, エルエルシー | 一日一回の投与のための吸収が制御された水溶性の薬学的に活性な有機化合物製剤 |
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