JP2017023143A5 - - Google Patents
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- Publication number
- JP2017023143A5 JP2017023143A5 JP2016144065A JP2016144065A JP2017023143A5 JP 2017023143 A5 JP2017023143 A5 JP 2017023143A5 JP 2016144065 A JP2016144065 A JP 2016144065A JP 2016144065 A JP2016144065 A JP 2016144065A JP 2017023143 A5 JP2017023143 A5 JP 2017023143A5
- Authority
- JP
- Japan
- Prior art keywords
- hev
- reaction mixture
- cell line
- hepg2
- concentration
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 241000724675 Hepatitis E virus Species 0.000 claims 23
- 238000000034 method Methods 0.000 claims 17
- 239000011541 reaction mixture Substances 0.000 claims 11
- 239000002299 complementary DNA Substances 0.000 claims 5
- 102000040430 polynucleotide Human genes 0.000 claims 5
- 108091033319 polynucleotide Proteins 0.000 claims 5
- 239000002157 polynucleotide Substances 0.000 claims 5
- 229920000209 Hexadimethrine bromide Polymers 0.000 claims 4
- 239000001963 growth medium Substances 0.000 claims 4
- 239000012620 biological material Substances 0.000 claims 3
- 239000003795 chemical substances by application Substances 0.000 claims 3
- 239000002609 medium Substances 0.000 claims 3
- 238000003556 assay Methods 0.000 claims 2
- 239000003153 chemical reaction reagent Substances 0.000 claims 2
- 230000000295 complement effect Effects 0.000 claims 2
- 239000000203 mixture Substances 0.000 claims 2
- FWMNVWWHGCHHJJ-SKKKGAJSSA-N 4-amino-1-[(2r)-6-amino-2-[[(2r)-2-[[(2r)-2-[[(2r)-2-amino-3-phenylpropanoyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]hexanoyl]piperidine-4-carboxylic acid Chemical compound C([C@H](C(=O)N[C@H](CC(C)C)C(=O)N[C@H](CCCCN)C(=O)N1CCC(N)(CC1)C(O)=O)NC(=O)[C@H](N)CC=1C=CC=CC=1)C1=CC=CC=C1 FWMNVWWHGCHHJJ-SKKKGAJSSA-N 0.000 claims 1
- 238000012258 culturing Methods 0.000 claims 1
- 239000003814 drug Substances 0.000 claims 1
- 229940079593 drug Drugs 0.000 claims 1
- 238000000338 in vitro Methods 0.000 claims 1
- 239000002773 nucleotide Substances 0.000 claims 1
- 125000003729 nucleotide group Chemical group 0.000 claims 1
- 229920001184 polypeptide Polymers 0.000 claims 1
- 102000004196 processed proteins & peptides Human genes 0.000 claims 1
- 108090000765 processed proteins & peptides Proteins 0.000 claims 1
- 238000004448 titration Methods 0.000 claims 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201562195936P | 2015-07-23 | 2015-07-23 | |
| US62/195,936 | 2015-07-23 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2017023143A JP2017023143A (ja) | 2017-02-02 |
| JP2017023143A5 true JP2017023143A5 (enExample) | 2018-09-06 |
| JP6588397B2 JP6588397B2 (ja) | 2019-10-09 |
Family
ID=56409494
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016144065A Active JP6588397B2 (ja) | 2015-07-23 | 2016-07-22 | 高力価のe型肝炎ウイルスストックを生成する方法及びe型肝炎ウイルスの力価測定アッセイ |
Country Status (22)
| Country | Link |
|---|---|
| US (1) | US10208291B2 (enExample) |
| EP (1) | EP3121267B1 (enExample) |
| JP (1) | JP6588397B2 (enExample) |
| KR (1) | KR102154380B1 (enExample) |
| CN (1) | CN106367397B (enExample) |
| AR (1) | AR106015A1 (enExample) |
| AU (1) | AU2016204734B2 (enExample) |
| BR (1) | BR102016016677A2 (enExample) |
| CA (1) | CA2937088C (enExample) |
| CL (1) | CL2016001768A1 (enExample) |
| ES (1) | ES2669021T3 (enExample) |
| HU (1) | HUE036699T2 (enExample) |
| IL (1) | IL246634B (enExample) |
| MX (1) | MX375106B (enExample) |
| MY (1) | MY176204A (enExample) |
| NZ (1) | NZ722213A (enExample) |
| PL (1) | PL3121267T3 (enExample) |
| PT (1) | PT3121267T (enExample) |
| RU (1) | RU2691123C1 (enExample) |
| SG (1) | SG10201605867UA (enExample) |
| TW (1) | TWI666322B (enExample) |
| UY (1) | UY36778A (enExample) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR102158641B1 (ko) * | 2019-03-06 | 2020-09-22 | 대한민국 | 야누스 인산화효소 저해제 및 헥사디메트린 브로마이드를 포함하는 바이러스 배양용 조성물 및 이를 이용한 바이러스 배양 방법 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6506604B2 (en) * | 1993-06-11 | 2003-01-14 | Cell Genesys, Inc. | Method for production of high titer virus and high efficiency retroviral mediated transduction of mammalian cells |
| US6217858B1 (en) * | 1997-02-11 | 2001-04-17 | Hadasit & Medical Research Services & Development Company, Ltd. | Pharmaceutical composition for treating hepatitis B virus (HBV) infection |
| WO2003001198A1 (en) * | 2001-06-21 | 2003-01-03 | Regents Of The University Of California | Immortalization of human cells by the ectopic expression of human telomerase reverse transcriptase |
| WO2007046962A2 (en) * | 2005-09-02 | 2007-04-26 | The University Of Maryland, Baltimore | Cell lines harboring hepatitis virus and methods for using thereof |
| JP2012504647A (ja) * | 2008-10-03 | 2012-02-23 | ザ ロックフェラー ユニヴァーシティ | 新規なhcv侵入因子、オクルディン |
| US9181530B2 (en) * | 2011-01-10 | 2015-11-10 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Infectious hepatitis E virus genotype 3 recombinants |
| US9789139B2 (en) * | 2011-06-10 | 2017-10-17 | Bluebird Bio, Inc. | Gene therapy vectors for adrenoleukodystrophy and adrenomyeloneuropathy |
-
2016
- 2016-07-06 IL IL246634A patent/IL246634B/en active IP Right Grant
- 2016-07-07 UY UY0001036778A patent/UY36778A/es not_active Application Discontinuation
- 2016-07-08 AU AU2016204734A patent/AU2016204734B2/en active Active
- 2016-07-08 MX MX2016009048A patent/MX375106B/es active IP Right Grant
- 2016-07-08 RU RU2016127546A patent/RU2691123C1/ru active
- 2016-07-11 EP EP16178844.3A patent/EP3121267B1/en active Active
- 2016-07-11 HU HUE16178844A patent/HUE036699T2/hu unknown
- 2016-07-11 PL PL16178844T patent/PL3121267T3/pl unknown
- 2016-07-11 CL CL2016001768A patent/CL2016001768A1/es unknown
- 2016-07-11 PT PT161788443T patent/PT3121267T/pt unknown
- 2016-07-11 ES ES16178844.3T patent/ES2669021T3/es active Active
- 2016-07-12 MY MYPI2016702506A patent/MY176204A/en unknown
- 2016-07-15 NZ NZ722213A patent/NZ722213A/en not_active IP Right Cessation
- 2016-07-18 CN CN201610566601.8A patent/CN106367397B/zh active Active
- 2016-07-18 SG SG10201605867UA patent/SG10201605867UA/en unknown
- 2016-07-19 US US15/213,766 patent/US10208291B2/en active Active
- 2016-07-19 BR BR102016016677-2A patent/BR102016016677A2/pt not_active Application Discontinuation
- 2016-07-20 TW TW105122892A patent/TWI666322B/zh not_active IP Right Cessation
- 2016-07-21 AR ARP160102202A patent/AR106015A1/es not_active Application Discontinuation
- 2016-07-22 JP JP2016144065A patent/JP6588397B2/ja active Active
- 2016-07-22 CA CA2937088A patent/CA2937088C/en active Active
- 2016-07-22 KR KR1020160093629A patent/KR102154380B1/ko not_active Expired - Fee Related
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