|
US5437291A
(en)
|
1993-08-26 |
1995-08-01 |
Univ Johns Hopkins |
Method for treating gastrointestinal muscle disorders and other smooth muscle dysfunction
|
|
US6974578B1
(en)
|
1993-12-28 |
2005-12-13 |
Allergan, Inc. |
Method for treating secretions and glands using botulinum toxin
|
|
US5766605A
(en)
|
1994-04-15 |
1998-06-16 |
Mount Sinai School Of Medicine Of The City University Of New York |
Treatment of autonomic nerve dysfunction with botulinum toxin
|
|
ATE215832T1
(de)
*
|
1994-05-09 |
2002-04-15 |
William J Binder |
Botulinumtoxin zur reduktion von migraine - kopfschmerzen
|
|
US5670484A
(en)
|
1994-05-09 |
1997-09-23 |
Binder; William J. |
Method for treatment of skin lesions associated with cutaneous cell-proliferative disorders
|
|
US6063768A
(en)
|
1997-09-04 |
2000-05-16 |
First; Eric R. |
Application of botulinum toxin to the management of neurogenic inflammatory disorders
|
|
US6265379B1
(en)
|
1999-10-13 |
2001-07-24 |
Allergan Sales, Inc. |
Method for treating otic disorders
|
|
US6139845A
(en)
|
1999-12-07 |
2000-10-31 |
Allergan Sales, Inc. |
Method for treating cancer with a neurotoxin
|
|
US20030118598A1
(en)
*
|
2000-02-08 |
2003-06-26 |
Allergan, Inc. |
Clostridial toxin pharmaceutical compositions
|
|
US8632785B2
(en)
*
|
2000-02-08 |
2014-01-21 |
Allergan, Inc. |
Clostridial toxin pharmaceutical composition containing a gelatin fragment
|
|
US20060269575A1
(en)
*
|
2000-02-08 |
2006-11-30 |
Allergan, Inc. |
Botulinum toxin pharmaceutical compositions formulated with recombinant albumin
|
|
US7780967B2
(en)
*
|
2000-02-08 |
2010-08-24 |
Allergan, Inc. |
Reduced toxicity Clostridial toxin pharmaceutical compositions
|
|
US6464986B1
(en)
|
2000-04-14 |
2002-10-15 |
Allegan Sales, Inc. |
Method for treating pain by peripheral administration of a neurotoxin
|
|
US6299893B1
(en)
|
2000-04-17 |
2001-10-09 |
Marvin Schwartz |
Method to reduce hair loss and stimulate hair regrowth
|
|
US20040033241A1
(en)
*
|
2000-06-02 |
2004-02-19 |
Allergan, Inc. |
Controlled release botulinum toxin system
|
|
US6423319B1
(en)
|
2000-10-04 |
2002-07-23 |
Allergan Sales, Inc. |
Methods for treating muscle injuries
|
|
JP4138651B2
(ja)
|
2001-07-27 |
2008-08-27 |
ボード オブ スーパーバイザーズ オブ ルイジアナ ステイト ユニバーシティ アンド アグリカルチュラル アンド メカニカル カレッジ |
にきび治療または防止のためのボツリヌス毒素
|
|
MXPA01011542A
(es)
*
|
2001-11-13 |
2003-05-22 |
Alcon Inc |
Regeneracion del cartilago articular da°ado por la osteoartritis de grado i y ii, mediante la aplicacion intra-articular de una mezcla de hialuronato de sodio y de condroitin sulfato en un vehiculo de gel.
|
|
US7459164B2
(en)
|
2002-05-28 |
2008-12-02 |
Botulinum Toxin Research Associates, Inc. |
Composition for therapeutic and cosmetic botulinum toxin
|
|
US7691394B2
(en)
*
|
2002-05-28 |
2010-04-06 |
Botulinum Toxin Research Associates, Inc. |
High-potency botulinum toxin formulations
|
|
US20030224020A1
(en)
|
2002-05-31 |
2003-12-04 |
Zabudkin Alexander F. |
Pharmaceutical preparation of botulinum neurotoxin, methods of synthesis and methods of clinical use
|
|
NZ540425A
(en)
*
|
2002-12-20 |
2009-03-31 |
Botulinum Toxin Res Ass Inc |
Pharmaceutical botulinum toxin compositions
|
|
US7396535B2
(en)
*
|
2003-04-25 |
2008-07-08 |
Ackerman Alan H |
Therapy for obsessive compulsive head banging
|
|
DE10333317A1
(de)
*
|
2003-07-22 |
2005-02-17 |
Biotecon Therapeutics Gmbh |
Formulierung für Proteinarzneimittel ohne Zusatz von humanem Serumalbumin (HSA)
|
|
US7160699B2
(en)
*
|
2003-09-25 |
2007-01-09 |
Allergan, Inc. |
Media for clostridium bacterium and processes for obtaining a clostridial toxin
|
|
US20100266638A1
(en)
*
|
2004-02-26 |
2010-10-21 |
Allergan, Inc. |
Headache treatment method
|
|
US9078892B2
(en)
*
|
2004-02-26 |
2015-07-14 |
Allergan, Inc. |
Methods for treating pain and for treating a medication overuse disorder
|
|
US20050191321A1
(en)
*
|
2004-02-26 |
2005-09-01 |
Allergan, Inc. |
Methods for treating headache
|
|
GB2416122A
(en)
|
2004-07-12 |
2006-01-18 |
Ipsen Ltd |
Botulinum neurotoxin composition
|
|
EP1786459B1
(en)
*
|
2004-07-26 |
2014-02-12 |
Merz Pharma GmbH & Co. KGaA |
Therapeutic composition whit a botulinum neurotoxin
|
|
WO2006013357A1
(en)
*
|
2004-08-04 |
2006-02-09 |
Ipsen Limited |
Pharmaceutical composition containing botulinum neurotoxin a2
|
|
US20060073208A1
(en)
*
|
2004-10-01 |
2006-04-06 |
Allergan, Inc. |
Cosmetic neurotoxin compositions and methods
|
|
CN1930186A
(zh)
*
|
2005-03-03 |
2007-03-14 |
阿勒根公司 |
为获得梭菌毒素的梭菌细菌培养基及方法
|
|
WO2006122123A2
(en)
*
|
2005-05-09 |
2006-11-16 |
Levin Bruce H |
Methods of alleviating disorders and their associated pain
|
|
US8926991B2
(en)
*
|
2005-06-14 |
2015-01-06 |
Botulinum Toxin Research Associates, Inc. |
Botulinum toxin and the treatment of primary disorders of mood and affect
|
|
US8323666B2
(en)
*
|
2005-08-01 |
2012-12-04 |
Allergan, Inc. |
Botulinum toxin compositions
|
|
US7744904B1
(en)
*
|
2005-09-26 |
2010-06-29 |
B.B. Scientific L.L.C. |
Stabilization of Clostridium botulinum neurotoxin complex
|
|
US8137677B2
(en)
*
|
2005-10-06 |
2012-03-20 |
Allergan, Inc. |
Non-protein stabilized clostridial toxin pharmaceutical compositions
|
|
US8168206B1
(en)
*
|
2005-10-06 |
2012-05-01 |
Allergan, Inc. |
Animal protein-free pharmaceutical compositions
|
|
WO2007044809A2
(en)
*
|
2005-10-11 |
2007-04-19 |
Botulinum Toxin Research Associates, Inc. |
Albumin-free botulinum toxin based pharmaceutical compositions containing a hyaluronidase and methods of use
|
|
US9061025B2
(en)
*
|
2006-08-31 |
2015-06-23 |
Allergan, Inc. |
Methods for selecting headache patients responsive to botulinum toxin therapy
|
|
FR2910327B1
(fr)
|
2006-12-22 |
2013-04-26 |
Scras |
Utilisation d'au moins une neurotoxine botulique pour traiter la douleur induite par les traitements therapeutiques du virus du sida.
|
|
CA2690773C
(en)
*
|
2007-07-10 |
2013-09-17 |
Medy-Tox, Inc. |
Pharmaceutical liquid composition of botulinum toxin with improved stability
|
|
US9161970B2
(en)
*
|
2007-12-12 |
2015-10-20 |
Allergan, Inc. |
Dermal filler
|
|
US9044477B2
(en)
*
|
2007-12-12 |
2015-06-02 |
Allergan, Inc. |
Botulinum toxin formulation
|
|
EP2072039A1
(en)
*
|
2007-12-21 |
2009-06-24 |
Merz Pharma GmbH & Co.KGaA |
Use of a neurotoxic component of Clostridium botulinum toxin complex to reduce or prevent side effects
|
|
US9107815B2
(en)
*
|
2008-02-22 |
2015-08-18 |
Allergan, Inc. |
Sustained release poloxamer containing pharmaceutical compositions
|
|
US8617571B2
(en)
*
|
2008-04-03 |
2013-12-31 |
Allergan, Inc. |
Suture line administration technique using botulinum toxin
|
|
KR20090120222A
(ko)
*
|
2008-05-19 |
2009-11-24 |
(주)메디톡스 |
식물 유래 성분 함유 배지 및 가요성 폐쇄 용기를 이용하여클로스트리디움 보툴리눔 독소를 생산하는 방법
|
|
US8535276B2
(en)
*
|
2008-06-26 |
2013-09-17 |
Bellanovus Development Company Llc |
Syringe-attached topical anesthetic dispenser
|
|
CA2745657C
(en)
*
|
2008-12-04 |
2022-06-21 |
Botulinum Toxin Research Associates, Inc. |
Extended length botulinum toxin formulation for human or mammalian use
|
|
AU2009339292B2
(en)
|
2008-12-10 |
2016-01-21 |
Allergan, Inc. |
Clostridial toxin pharmaceutical compositions
|
|
LT2379104T
(lt)
*
|
2008-12-31 |
2018-04-10 |
Revance Therapeutics, Inc. |
Injekcinės botulino toksino vaisto formos
|
|
CA2749034C
(en)
|
2009-01-07 |
2019-01-15 |
Robert John Petrella |
Treatment of soft tissue injury using hyaluronic acid and botulinum toxin
|
|
EP2248518B1
(en)
*
|
2009-04-17 |
2013-01-16 |
Merz Pharma GmbH & Co. KGaA |
Formulation for stabilizing proteins, peptides or mixtures thereof.
|
|
US20120295914A1
(en)
|
2009-05-29 |
2012-11-22 |
Galderma Research & Development |
Combination of adrenergic receptor agonist alpha-1 or alpha-2, preferably brimonidine with fillers, preferably hyaluronic acid
|
|
CN102869373B
(zh)
*
|
2009-06-25 |
2017-05-10 |
雷文斯治疗公司 |
不含白蛋白的肉毒杆菌毒素制剂
|
|
JP5889185B2
(ja)
*
|
2009-06-30 |
2016-03-22 |
株式会社アモーレパシフィックＡｍｏｒｅｐａｃｉｆｉｃ Ｃｏｒｐｏｒａｔｉｏｎ |
トックリイチゴ酒蒸抽出物の製造方法
|
|
US8129139B2
(en)
*
|
2009-07-13 |
2012-03-06 |
Allergan, Inc. |
Process for obtaining botulinum neurotoxin
|
|
US20120196349A1
(en)
|
2009-10-21 |
2012-08-02 |
Revance Therapeutics, Inc. |
Methods and Systems for Purifying Non-Complexed Botulinum Neurotoxin
|
|
BR112012010058A2
(pt)
*
|
2009-10-30 |
2016-05-31 |
Duoject Inc |
aplicador tópico para um agente paralítico e método para aplicação do agente
|
|
WO2011075623A1
(en)
*
|
2009-12-18 |
2011-06-23 |
Latitude Pharmaceuticals, Inc. |
One - phase gel compos ition compri s ing phos pholi pids
|
|
US8940308B2
(en)
*
|
2010-03-30 |
2015-01-27 |
Allergan, Inc. |
Methods for treating depression
|
|
JP5990176B2
(ja)
*
|
2010-10-12 |
2016-09-07 |
メルツ ファーマ ゲゼルシャフト ミット ベシュレンクテル ハフツング ウント コンパニー コマンディト ゲゼルシャフト アウフ アクティーン |
タンパク質の安定化に好適な哺乳動物性賦形剤非含有製剤
|
|
MX338436B
(es)
*
|
2011-03-31 |
2016-04-18 |
Medy Tox Inc |
Preparacion liofilizada de toxinas de botulismo.
|
|
KR20130022923A
(ko)
*
|
2011-08-26 |
2013-03-07 |
삼성전자주식회사 |
가상 시점 합성 예측을 이용한 부호화/복호화 장치 및 부호화/복호화 방법
|
|
SG11201403714TA
(en)
*
|
2011-12-30 |
2014-07-30 |
Halozyme Inc |
Ph20 polypeptide variants, formulations and uses thereof
|
|
WO2013151664A1
(en)
*
|
2012-04-02 |
2013-10-10 |
modeRNA Therapeutics |
Modified polynucleotides for the production of proteins
|
|
US9480731B2
(en)
*
|
2013-12-12 |
2016-11-01 |
Medy-Tox, Inc. |
Long lasting effect of new botulinum toxin formulations
|
|
EP3109609B1
(en)
|
2014-03-18 |
2020-10-21 |
Hitachi Metals, Ltd. |
Electroconductive resin composition and pressure sensor
|
|
US9579502B2
(en)
*
|
2014-04-19 |
2017-02-28 |
Medtronic, Inc. |
Implantable medical leads, systems, and related methods for creating a high impedance within a conduction path in the presence of a magnetic field of a given strength
|
|
JP7120765B2
(ja)
*
|
2015-11-25 |
2022-08-17 |
レゴケム バイオサイエンシズ， インク． |
ペプチド基を含む複合体及びそれに関連する方法
|
|
HRP20251606T1
(hr)
|
2016-05-27 |
2026-02-13 |
Ipsen Biopharm Limited |
Tekuća neurotoksinska formulacija stabilizirana s triptofanom ili tirozinom
|
|
WO2018038301A1
(en)
|
2016-08-26 |
2018-03-01 |
Hugel Inc. |
Stabilized liquid formulation of botulinum toxin and preparation method thereof
|
|
KR102463881B1
(ko)
*
|
2016-10-04 |
2022-11-07 |
(주)메디톡스 |
보툴리눔 독소 함유 용액으로부터 보툴리눔 독소를 분리하는 방법
|
|
KR102088104B1
(ko)
*
|
2018-06-29 |
2020-03-11 |
호서대학교 산학협력단 |
개망초 꽃 에센셜 오일을 포함하는 신경 근육 관련 질환 예방 및 치료용 조성물
|
|
BR112021004771A2
(pt)
*
|
2018-09-13 |
2021-11-09 |
Allergan Inc |
Composições de ácido hialurônico-toxina clostridial
|
|
KR101968873B1
(ko)
*
|
2018-09-21 |
2019-04-29 |
아이큐어 주식회사 |
세포 침투 효과가 우수한 보툴리늄 유래 펩타이드를 포함하는 화장료 조성물
|
|
UY38744A
(es)
|
2019-06-07 |
2020-12-31 |
Nestle Skin Health S A |
Tratamiento de líneas glabelares y líneas cantales laterales de moderadas a muy graves
|