JP2016539131A5 - - Google Patents
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- Publication number
- JP2016539131A5 JP2016539131A5 JP2016535210A JP2016535210A JP2016539131A5 JP 2016539131 A5 JP2016539131 A5 JP 2016539131A5 JP 2016535210 A JP2016535210 A JP 2016535210A JP 2016535210 A JP2016535210 A JP 2016535210A JP 2016539131 A5 JP2016539131 A5 JP 2016539131A5
- Authority
- JP
- Japan
- Prior art keywords
- salt
- arachidylamide
- cholan
- dihydroxy
- amine
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361911478P | 2013-12-04 | 2013-12-04 | |
| US61/911,478 | 2013-12-04 | ||
| PCT/IL2014/051052 WO2015083164A1 (en) | 2013-12-04 | 2014-12-04 | Aramchol salts |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020040825A Division JP2020111584A (ja) | 2013-12-04 | 2020-03-10 | アラムコール塩 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2016539131A JP2016539131A (ja) | 2016-12-15 |
| JP2016539131A5 true JP2016539131A5 (https=) | 2018-01-18 |
| JP6675310B2 JP6675310B2 (ja) | 2020-04-01 |
Family
ID=53272986
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016535210A Active JP6675310B2 (ja) | 2013-12-04 | 2014-12-04 | アラムコール塩 |
| JP2020040825A Pending JP2020111584A (ja) | 2013-12-04 | 2020-03-10 | アラムコール塩 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020040825A Pending JP2020111584A (ja) | 2013-12-04 | 2020-03-10 | アラムコール塩 |
Country Status (21)
| Country | Link |
|---|---|
| US (1) | US20160304553A1 (https=) |
| EP (1) | EP3077047B1 (https=) |
| JP (2) | JP6675310B2 (https=) |
| KR (1) | KR102320191B1 (https=) |
| CN (2) | CN110437298A (https=) |
| AU (2) | AU2014358668B2 (https=) |
| BR (1) | BR112016012465B1 (https=) |
| CA (1) | CA2930232C (https=) |
| CY (1) | CY1121736T1 (https=) |
| DK (1) | DK3077047T3 (https=) |
| ES (1) | ES2732845T3 (https=) |
| HR (1) | HRP20191023T1 (https=) |
| HU (1) | HUE045209T2 (https=) |
| LT (1) | LT3077047T (https=) |
| PL (1) | PL3077047T3 (https=) |
| PT (1) | PT3077047T (https=) |
| RS (1) | RS59067B1 (https=) |
| SI (1) | SI3077047T1 (https=) |
| SM (1) | SMT201900363T1 (https=) |
| TR (1) | TR201909447T4 (https=) |
| WO (1) | WO2015083164A1 (https=) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL227890A0 (en) * | 2013-08-08 | 2014-01-30 | Galderm Therapeutics Ltd | Antiaging compounds containing bile acid and fatty acid conjugates |
| SI3077047T1 (sl) * | 2013-12-04 | 2019-09-30 | Galmed Research & Development Ltd. | Soli aramchola |
| US10849911B2 (en) | 2015-06-10 | 2020-12-01 | Galmed Research And Development Ltd. | Low dose compositions of Aramachol salts |
| CN108337879B (zh) * | 2015-07-12 | 2021-01-19 | 西夫索有限公司 | 硫酸胆钙化醇的盐及其用于治疗维生素d3缺乏的用途 |
| WO2017017677A1 (en) * | 2015-07-27 | 2017-02-02 | Galmed Research And Development Ltd. | Combination treatment for liver disease |
| IL243707A0 (en) | 2016-01-20 | 2016-05-01 | Galmed Res And Dev Ltd | Treatment to regulate the microbiota in the intestine |
| FR3050112B1 (fr) | 2016-04-15 | 2020-09-04 | Soc Civ Immobiliere Gecinq | Utilisation de l'acide fenofibrique dans le traitement des maladies hepatiques |
| EP3518918A4 (en) * | 2016-09-28 | 2020-04-22 | Eiger Biopharmaceuticals, Inc. | METHOD AND PHARMACEUTICAL COMPOSITIONS FOR TREATING NON-ALCOHOLIC STEATOHEPATITIS |
| US11197870B2 (en) | 2016-11-10 | 2021-12-14 | Galmed Research And Development Ltd | Treatment for hepatic fibrosis |
| MA46786A (fr) * | 2016-11-10 | 2019-09-18 | Galmed Res And Development Ltd | Inhibition de la fibrose chez des patients atteints d'une stéatose hépatique non alcoolique |
| US11136347B2 (en) | 2017-06-07 | 2021-10-05 | Crystal Pharmaceutical (Suzhou) Co., Ltd. | Crystalline forms of a fatty acid bile acid conjugate, preparation method thereof and use thereof |
| WO2019055280A1 (en) | 2017-09-13 | 2019-03-21 | Emmyon, Inc. | DIETHANOLAMINE SALTS AND URSOLIC ACID MORPHOLIN |
| US20190183832A1 (en) * | 2017-12-20 | 2019-06-20 | Michael Guarnieri | Nutritional bolus for animals |
| WO2020026471A1 (ja) * | 2018-07-31 | 2020-02-06 | 株式会社親広産業 | グルコース消費促進剤および解糖系促進剤 |
| JP6612004B1 (ja) * | 2018-07-31 | 2019-11-27 | 株式会社親広産業 | グルコース消費促進剤および解糖系促進剤 |
| CN117769561A (zh) * | 2021-04-19 | 2024-03-26 | 神经创伤科学有限责任公司 | (3E)3-[o-[(膦酰氧基)甲基]肟]-孕烯-4-烯-3,20-二酮的盐和晶型及相关用途 |
| US20260062432A1 (en) * | 2022-09-02 | 2026-03-05 | Rexpharmtech Co., Ltd | Novel benfotiamine choline salt |
| US12090151B1 (en) | 2023-05-12 | 2024-09-17 | Michael Guarnieri | Injectable sustained release buprenorphine formulation |
Family Cites Families (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2252863A (en) * | 1941-02-03 | 1941-08-19 | Searle & Co | Quaternary ammonium salts |
| GB1532413A (en) * | 1974-12-23 | 1978-11-15 | Union International Co Ltd | Chenodeoxycholic acid |
| IL123998A (en) * | 1998-04-08 | 2004-09-27 | Galmed Int Ltd | Conjugates of bile salts and pharmaceutical preparations containing them |
| IL142650A (en) * | 1998-04-08 | 2007-06-03 | Galmed Int Ltd | Use of bile acid conjugates or bile salts and fatty acids or fatty acids in the preparation of pharmaceuticals for lowering cholesterol, for the treatment of fatty liver and for the treatment of hyperglycemia and diabetes |
| CA2386190C (en) * | 1999-10-13 | 2009-04-14 | Johns Hopkins University School Of Medicine | Regulators of the hedgehog pathway, compositions and uses related thereto |
| US8975246B2 (en) * | 2001-04-17 | 2015-03-10 | Galmed Research And Development Ltd. | Bile acid or bile salt fatty acid conjugates |
| CN1950086A (zh) * | 2004-04-28 | 2007-04-18 | 默克公司 | 作为雄激素受体调节剂的氟化的4－氮杂甾族化合物 |
| ITMI20061735A1 (it) * | 2006-09-12 | 2008-03-13 | Dipharma Spa | Procedimento per la preparazione di acidi colanici |
| DE102007032507A1 (de) * | 2007-07-12 | 2009-04-02 | Merck Patent Gmbh | Pyridazinonderivate |
| US20120157419A1 (en) * | 2009-02-02 | 2012-06-21 | Tuvia Gilat | Methods and compositions for treating alzheimer's disease |
| US20120251492A1 (en) * | 2009-12-15 | 2012-10-04 | Meiji Seika Pharma Co., Ltd. | Triterpene derivative and agent for preventing or treating chronic hepatitis c |
| CN102115486B (zh) * | 2009-12-30 | 2015-06-03 | 上海特化医药科技有限公司 | 一种3-β-花生酰胺基-7α,12α,5β-胆烷-24-羧酸的制备方法 |
| BR112012018913A2 (pt) * | 2010-01-28 | 2017-06-20 | Merck Sharp & Dohme | "composição farmacêutica, e, uso da composição" |
| PL2531501T3 (pl) * | 2010-02-03 | 2014-05-30 | Takeda Pharmaceuticals Co | Inhibitory kinazy 1 regulującej sygnał apoptotyczny |
| EP3360552A1 (en) * | 2010-12-07 | 2018-08-15 | Amira Pharmaceuticals, Inc. | Polycyclic lpa1 antagonist and uses thereof |
| SI3077047T1 (sl) * | 2013-12-04 | 2019-09-30 | Galmed Research & Development Ltd. | Soli aramchola |
-
2014
- 2014-12-04 SI SI201431253T patent/SI3077047T1/sl unknown
- 2014-12-04 JP JP2016535210A patent/JP6675310B2/ja active Active
- 2014-12-04 US US15/100,993 patent/US20160304553A1/en not_active Abandoned
- 2014-12-04 PL PL14868582T patent/PL3077047T3/pl unknown
- 2014-12-04 BR BR112016012465-0A patent/BR112016012465B1/pt active IP Right Grant
- 2014-12-04 HU HUE14868582A patent/HUE045209T2/hu unknown
- 2014-12-04 CN CN201910687060.8A patent/CN110437298A/zh active Pending
- 2014-12-04 KR KR1020167017460A patent/KR102320191B1/ko active Active
- 2014-12-04 HR HRP20191023TT patent/HRP20191023T1/hr unknown
- 2014-12-04 SM SM20190363T patent/SMT201900363T1/it unknown
- 2014-12-04 TR TR2019/09447T patent/TR201909447T4/tr unknown
- 2014-12-04 CA CA2930232A patent/CA2930232C/en active Active
- 2014-12-04 DK DK14868582.9T patent/DK3077047T3/da active
- 2014-12-04 EP EP14868582.9A patent/EP3077047B1/en active Active
- 2014-12-04 AU AU2014358668A patent/AU2014358668B2/en active Active
- 2014-12-04 CN CN201480064913.8A patent/CN105848718B/zh active Active
- 2014-12-04 WO PCT/IL2014/051052 patent/WO2015083164A1/en not_active Ceased
- 2014-12-04 RS RS20190787A patent/RS59067B1/sr unknown
- 2014-12-04 LT LTEP14868582.9T patent/LT3077047T/lt unknown
- 2014-12-04 ES ES14868582T patent/ES2732845T3/es active Active
- 2014-12-04 PT PT14868582T patent/PT3077047T/pt unknown
-
2019
- 2019-07-01 CY CY20191100688T patent/CY1121736T1/el unknown
- 2019-12-06 AU AU2019275638A patent/AU2019275638B2/en active Active
-
2020
- 2020-03-10 JP JP2020040825A patent/JP2020111584A/ja active Pending
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