JP2016535780A - 慢性腎臓病患者の心不全を軽減するためのクエン酸第二鉄 - Google Patents

慢性腎臓病患者の心不全を軽減するためのクエン酸第二鉄 Download PDF

Info

Publication number
JP2016535780A
JP2016535780A JP2016552432A JP2016552432A JP2016535780A JP 2016535780 A JP2016535780 A JP 2016535780A JP 2016552432 A JP2016552432 A JP 2016552432A JP 2016552432 A JP2016552432 A JP 2016552432A JP 2016535780 A JP2016535780 A JP 2016535780A
Authority
JP
Japan
Prior art keywords
ferric citrate
iron
patient
ckd
serum
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2016552432A
Other languages
English (en)
Japanese (ja)
Other versions
JP2016535780A5 (https=
Inventor
ポラドス エンリクエ
ポラドス エンリクエ
ベントスル ロン
ベントスル ロン
エフ．オリビエロ サード ジェームス
エフ．オリビエロ サード ジェームス
Original Assignee
ケリク バイオファーマシューティカルス， インコーポレーテッド
ケリク バイオファーマシューティカルス， インコーポレーテッド
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ケリク バイオファーマシューティカルス， インコーポレーテッド, ケリク バイオファーマシューティカルス， インコーポレーテッド filed Critical ケリク バイオファーマシューティカルス， インコーポレーテッド
Publication of JP2016535780A publication Critical patent/JP2016535780A/ja
Publication of JP2016535780A5 publication Critical patent/JP2016535780A5/ja
Pending legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/24—Heavy metals; Compounds thereof
    • A61K33/26—Iron; Compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/12—Drugs for disorders of the metabolism for electrolyte homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Cardiology (AREA)
  • Epidemiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Inorganic Chemistry (AREA)
  • Urology & Nephrology (AREA)
  • Hospice & Palliative Care (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Vascular Medicine (AREA)
  • Diabetes (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
JP2016552432A 2013-11-04 2014-11-03 慢性腎臓病患者の心不全を軽減するためのクエン酸第二鉄 Pending JP2016535780A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201361899866P 2013-11-04 2013-11-04
US61/899,866 2013-11-04
PCT/US2014/063643 WO2015066593A1 (en) 2013-11-04 2014-11-03 Ferric citrate for reducing cardiac failure in chronic kidney disease patients

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2019140640A Division JP6828100B2 (ja) 2013-11-04 2019-07-31 慢性腎臓病患者の心不全を軽減するためのクエン酸第二鉄

Publications (2)

Publication Number Publication Date
JP2016535780A true JP2016535780A (ja) 2016-11-17
JP2016535780A5 JP2016535780A5 (https=) 2017-12-14

Family

ID=53005244

Family Applications (3)

Application Number Title Priority Date Filing Date
JP2016552432A Pending JP2016535780A (ja) 2013-11-04 2014-11-03 慢性腎臓病患者の心不全を軽減するためのクエン酸第二鉄
JP2019140640A Active JP6828100B2 (ja) 2013-11-04 2019-07-31 慢性腎臓病患者の心不全を軽減するためのクエン酸第二鉄
JP2021007091A Pending JP2021073230A (ja) 2013-11-04 2021-01-20 慢性腎臓病患者の心不全を軽減するためのクエン酸第二鉄

Family Applications After (2)

Application Number Title Priority Date Filing Date
JP2019140640A Active JP6828100B2 (ja) 2013-11-04 2019-07-31 慢性腎臓病患者の心不全を軽減するためのクエン酸第二鉄
JP2021007091A Pending JP2021073230A (ja) 2013-11-04 2021-01-20 慢性腎臓病患者の心不全を軽減するためのクエン酸第二鉄

Country Status (15)

Country Link
US (3) US20160256486A1 (https=)
EP (2) EP3747432A1 (https=)
JP (3) JP2016535780A (https=)
KR (1) KR102392441B1 (https=)
CN (1) CN105873583A (https=)
AU (1) AU2014341975A1 (https=)
BR (1) BR112016009901A8 (https=)
CA (1) CA2928200A1 (https=)
EA (1) EA201690926A1 (https=)
HK (1) HK1223031A1 (https=)
IL (1) IL245317A0 (https=)
MX (1) MX2016005734A (https=)
SG (1) SG11201603091QA (https=)
TW (2) TW202203910A (https=)
WO (1) WO2015066593A1 (https=)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108938585A (zh) 2009-07-21 2018-12-07 凯克斯生物制药公司 柠檬酸铁剂型
SI3287133T1 (sl) 2013-06-05 2019-09-30 Tricida Inc. Polimeri, ki vežejo protone,za peroralno dajanje
EP3157516A4 (en) 2014-06-22 2017-12-13 Dexcel Pharma Technologies Ltd. Pharmaceutical compositions comprising ferric citrate and methods for the production thereof
LT3229816T (lt) 2014-12-10 2020-05-25 Tricida Inc. Protoną prijungiantys polimerai, skirti peroraliniam įvedimui
WO2017193024A1 (en) 2016-05-06 2017-11-09 Tricida, Inc. Hcl-binding compositions for and method of treating acid-base disorders
IL319146A (en) 2017-11-03 2025-04-01 Tricida Inc Compositions for and method of treating acid-base disorders
JP2022505697A (ja) 2018-10-29 2022-01-14 ファーマコスモス ホールディング エー／エス カルボキシマルトース第二鉄による鉄欠乏症の治療
EA202191858A1 (ru) * 2019-06-12 2021-11-12 Фармакосмос Холдинг А/С Лечение дефицита железа у субъектов с риском нежелательных явлений со стороны сердечно-сосудистой системы и железо для лечения фибрилляции предсердий
CN117999069A (zh) * 2021-05-27 2024-05-07 凯克斯生物制药公司 柠檬酸铁的儿科调配物

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2009504777A (ja) * 2005-08-18 2009-02-05 グロボアジア エルエルシー 医薬グレードの第二鉄有機化合物、その使用およびその製造方法
JP2009525277A (ja) * 2006-01-30 2009-07-09 グロボアジア エルエルシー 軟組織石灰化の回復、予防、遅延または安定化方法
JP2013533886A (ja) * 2010-07-07 2013-08-29 アーデリクス，インコーポレーテッド リン酸輸送を阻害する化合物及び方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE351366B (https=) * 1965-06-08 1972-11-27 Teikoku Hormone Mfg Co Ltd
US20050203169A1 (en) * 2001-08-06 2005-09-15 Moskowitz David W. Methods and compositions for treating diseases associated with excesses in ACE
US8093423B2 (en) 2003-02-19 2012-01-10 Globoasia, Llc Pharmaceutical-grade ferric organic compounds, uses thereof and method of making same
TWI335218B (en) 2003-02-19 2011-01-01 Panion & Bf Biotech Inc Ferric organic compounds, uses thereof and methods of making same
KR20080094013A (ko) * 2006-01-30 2008-10-22 글로보아시아 엘엘씨 연조직의 석회화 역전, 예방, 지연 또는 안정화 방법
CN108938585A (zh) * 2009-07-21 2018-12-07 凯克斯生物制药公司 柠檬酸铁剂型
SG11201408521WA (en) * 2012-06-21 2015-01-29 Keryx Biopharmaceuticals Inc Use of ferric citrate in the treatment of chronic kidney disease patients

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2009504777A (ja) * 2005-08-18 2009-02-05 グロボアジア エルエルシー 医薬グレードの第二鉄有機化合物、その使用およびその製造方法
JP2009525277A (ja) * 2006-01-30 2009-07-09 グロボアジア エルエルシー 軟組織石灰化の回復、予防、遅延または安定化方法
JP2013533886A (ja) * 2010-07-07 2013-08-29 アーデリクス，インコーポレーテッド リン酸輸送を阻害する化合物及び方法

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
AMERICAN J. OF NEPHROLOGY, vol. 36(5), JPN6018024257, 2012, pages 478 - 487, ISSN: 0004009684 *
AMERICAN J. OF NEPHROLOGY, vol. 37(4), JPN6018024258, 2013, pages 346 - 358, ISSN: 0004009685 *

Also Published As

Publication number Publication date
TWI744215B (zh) 2021-11-01
TW202203910A (zh) 2022-02-01
JP2021073230A (ja) 2021-05-13
SG11201603091QA (en) 2016-05-30
IL245317A0 (en) 2016-06-30
US20160256486A1 (en) 2016-09-08
HK1223031A1 (zh) 2017-07-21
JP6828100B2 (ja) 2021-02-10
MX2016005734A (es) 2016-11-08
AU2014341975A1 (en) 2016-05-19
WO2015066593A1 (en) 2015-05-07
CA2928200A1 (en) 2015-05-07
KR20160096597A (ko) 2016-08-16
EP3065734A1 (en) 2016-09-14
JP2019206562A (ja) 2019-12-05
BR112016009901A8 (pt) 2020-04-14
KR102392441B1 (ko) 2022-05-02
EP3065734A4 (en) 2017-05-17
CN105873583A (zh) 2016-08-17
TW201609088A (zh) 2016-03-16
US20190307791A1 (en) 2019-10-10
US20250360167A1 (en) 2025-11-27
EA201690926A1 (ru) 2016-09-30
EP3747432A1 (en) 2020-12-09

Similar Documents

Publication Publication Date Title
JP6828100B2 (ja) 慢性腎臓病患者の心不全を軽減するためのクエン酸第二鉄
AU2018203205B2 (en) Use of ferric citrate in the treatment of chronic kidney disease patients
US20240075006A1 (en) Use of ferric citrate in the treatment of iron-deficiency anemia
US20240041816A1 (en) Use of ferric citrate in the treatment of chronic kidney disease patients
US20190269645A1 (en) Use of ferric citrate in the treatment of chronic kidney disease patients
HK1210013B (en) Use of ferric citrate in the treatment of chronic kidney disease patients
NZ742524B2 (en) Use of ferric citrate in the treatment of chronic kidney disease patients

Legal Events

Date Code Title Description
A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20171102

A621 Written request for application examination

Free format text: JAPANESE INTERMEDIATE CODE: A621

Effective date: 20171102

A977 Report on retrieval

Free format text: JAPANESE INTERMEDIATE CODE: A971007

Effective date: 20180627

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20180703

A601 Written request for extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A601

Effective date: 20180831

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20181227

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A821

Effective date: 20181227

A02 Decision of refusal

Free format text: JAPANESE INTERMEDIATE CODE: A02

Effective date: 20190402