JP2016534048A5 - - Google Patents

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Publication number
JP2016534048A5
JP2016534048A5 JP2016522040A JP2016522040A JP2016534048A5 JP 2016534048 A5 JP2016534048 A5 JP 2016534048A5 JP 2016522040 A JP2016522040 A JP 2016522040A JP 2016522040 A JP2016522040 A JP 2016522040A JP 2016534048 A5 JP2016534048 A5 JP 2016534048A5
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JP
Japan
Prior art keywords
cancer
compound according
aryl
alkyl
compound
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JP2016522040A
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English (en)
Japanese (ja)
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JP6765302B2 (ja
JP2016534048A (ja
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Priority claimed from PCT/CA2014/050974 external-priority patent/WO2015051458A1/en
Publication of JP2016534048A publication Critical patent/JP2016534048A/ja
Publication of JP2016534048A5 publication Critical patent/JP2016534048A5/ja
Application granted granted Critical
Publication of JP6765302B2 publication Critical patent/JP6765302B2/ja
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

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JP2016522040A 2013-10-08 2014-10-08 標的化化学療法に使用するための非白金ベースの抗がん化合物 Expired - Fee Related JP6765302B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201361887988P 2013-10-08 2013-10-08
US61/887,988 2013-10-08
PCT/CA2014/050974 WO2015051458A1 (en) 2013-10-08 2014-10-08 Non-platimun-based anti-cancer compounds for use in targeted chemotherapy

Publications (3)

Publication Number Publication Date
JP2016534048A JP2016534048A (ja) 2016-11-04
JP2016534048A5 true JP2016534048A5 (https=) 2018-02-15
JP6765302B2 JP6765302B2 (ja) 2020-10-07

Family

ID=52812401

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2016522040A Expired - Fee Related JP6765302B2 (ja) 2013-10-08 2014-10-08 標的化化学療法に使用するための非白金ベースの抗がん化合物

Country Status (8)

Country Link
US (2) US10463662B2 (https=)
EP (2) EP3578176A1 (https=)
JP (1) JP6765302B2 (https=)
KR (1) KR102307387B1 (https=)
CN (2) CN114380700A (https=)
AU (1) AU2014334461B2 (https=)
CA (1) CA2926571C (https=)
WO (1) WO2015051458A1 (https=)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3319968A1 (en) 2015-07-06 2018-05-16 Rodin Therapeutics, Inc. Heterobicyclic n-aminophenyl-amides as inhibitors of histone deacetylase
WO2017007756A1 (en) 2015-07-06 2017-01-12 Rodin Therapeutics, Inc Hetero-halo inhibitors of histone deacetylase
MX388576B (es) 2016-06-07 2025-03-20 Jacobio Pharmaceuticals Co Ltd Derivados heterociclicos novedosos utiles como inhibidores de shp2.
US11168068B2 (en) 2016-07-18 2021-11-09 Janssen Pharmaceutica Nv Tau PET imaging ligands
HUE057849T2 (hu) 2017-01-11 2022-06-28 Alkermes Inc Hiszton deacetiláz biciklusos gátlói
EA202190196A1 (ru) 2017-03-23 2021-08-31 Джакобио Фармасьютикалс Ко., Лтд. Новые гетероциклические производные, применимые в качестве ингибиторов shp2
LT3664802T (lt) 2017-08-07 2022-06-27 Alkermes, Inc. Bicikliniai histonų deacetilazės inhibitoriai
US20210393623A1 (en) 2018-09-26 2021-12-23 Jacobio Pharmaceuticals Co., Ltd. Novel Heterocyclic Derivatives Useful as SHP2 Inhibitors

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3822261A (en) * 1972-10-30 1974-07-02 Dow Chemical Co 5,6-dihalo-2-fluoroalkyl-1h-imidazo(4,5-b)pyrazines
EP0743855A1 (en) * 1994-01-03 1996-11-27 Acea Pharmaceuticals, Inc. 8-aza, 6-aza and 6,8-diaza-1,4-dihydroquinoxaline-2,3-diones and the use thereof as antagonists for the glycine/nmda receptor
US7622117B2 (en) * 2002-04-17 2009-11-24 Dynamis Therapeutics, Inc. 3-deoxyglucosone and skin
DE102004054545A1 (de) * 2004-09-16 2006-04-06 Max-Delbrück-Centrum für Molekulare Medizin Änderung des Beladungszustandes von MHC-Molekülen
US20060089316A1 (en) * 2004-10-25 2006-04-27 Brown Truman R Method for reducing a susceptibility to tumor formation induced by 3-deoxyglucosone and precursors thereof
GB0428082D0 (en) 2004-12-22 2005-01-26 Welcome Trust The Ltd Therapeutic compounds
EP1853583B1 (en) * 2005-02-16 2011-09-07 Schering Corporation Amine-linked pyridyl and phenyl substituted piperazine-piperidines with cxcr3 antagonist activity
CN101611007A (zh) 2006-12-20 2009-12-23 先灵公司 新颖的jnk抑制剂
MX2009013332A (es) * 2007-06-08 2010-01-25 Mannkind Corp Inhibidores de ire-1 alfa.
ATE551336T1 (de) * 2007-08-16 2012-04-15 Hoffmann La Roche Substituierte hydantoine
DK200801600A (en) 2008-11-17 2010-05-18 Engkilde Kaare Method for treatment of inflammatory diseases
EP2493862B1 (en) * 2009-10-28 2016-10-05 Newlink Genetics Corporation Imidazole derivatives as ido inhibitors
WO2012096813A1 (en) * 2011-01-11 2012-07-19 Merck Sharp & Dohme Corp. Imidazole derivatives
CN105164107B (zh) 2012-12-20 2017-12-05 卢庆彬 用于与放射结合使用的放射增敏剂化合物

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