JP2016532115A - 被験体において心不全を診断するための手段及び方法 - Google Patents

被験体において心不全を診断するための手段及び方法 Download PDF

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Publication number
JP2016532115A
JP2016532115A JP2016537328A JP2016537328A JP2016532115A JP 2016532115 A JP2016532115 A JP 2016532115A JP 2016537328 A JP2016537328 A JP 2016537328A JP 2016537328 A JP2016537328 A JP 2016537328A JP 2016532115 A JP2016532115 A JP 2016532115A
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Prior art keywords
sphingomyelin
cholesteryl ester
biomarkers
group
heart failure
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Ceased
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JP2016537328A
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English (en)
Japanese (ja)
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JP2016532115A5 (enExample
Inventor
ヴィット,ヘニング
カストラー,ユルゲン
ベタン,ビアンカ
ペーター,エリク
シャッツ,フィリップ
ディルク デュンゲン,ハンス
ディルク デュンゲン,ハンス
ダニエル トリッペル,トビアス
ダニエル トリッペル,トビアス
タイロビック,エルヴィス
アー. カトゥス,フューゴ
アー. カトゥス,フューゴ
フライ,ノルベルト
ヴァイス,タンヤ
Original Assignee
メタノミクス ゲーエムベーハー
メタノミクス ゲーエムベーハー
ルプレヒト−カールス−ウニベルジテート ハイデルベルク
ルプレヒト−カールス−ウニベルジテート ハイデルベルク
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Application filed by メタノミクス ゲーエムベーハー, メタノミクス ゲーエムベーハー, ルプレヒト−カールス−ウニベルジテート ハイデルベルク, ルプレヒト−カールス−ウニベルジテート ハイデルベルク filed Critical メタノミクス ゲーエムベーハー
Publication of JP2016532115A publication Critical patent/JP2016532115A/ja
Publication of JP2016532115A5 publication Critical patent/JP2016532115A5/ja
Ceased legal-status Critical Current

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    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/92Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving lipids, e.g. cholesterol, lipoproteins, or their receptors
    • GPHYSICS
    • G16INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16BBIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B50/00ICT programming tools or database systems specially adapted for bioinformatics
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2405/00Assays, e.g. immunoassays or enzyme assays, involving lipids
    • G01N2405/08Sphingolipids
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2560/00Chemical aspects of mass spectrometric analysis of biological material
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2570/00Omics, e.g. proteomics, glycomics or lipidomics; Methods of analysis focusing on the entire complement of classes of biological molecules or subsets thereof, i.e. focusing on proteomes, glycomes or lipidomes
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/32Cardiovascular disorders
    • G01N2800/325Heart failure or cardiac arrest, e.g. cardiomyopathy, congestive heart failure

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  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Physics & Mathematics (AREA)
  • Chemical & Material Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Immunology (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Analytical Chemistry (AREA)
  • Cell Biology (AREA)
  • Biophysics (AREA)
  • Microbiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Databases & Information Systems (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Bioethics (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Evolutionary Biology (AREA)
  • Medical Informatics (AREA)
  • Theoretical Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Endocrinology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
JP2016537328A 2013-08-30 2014-09-01 被験体において心不全を診断するための手段及び方法 Ceased JP2016532115A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP13182441 2013-08-30
EP13182441.9 2013-08-30
PCT/EP2014/068530 WO2015028671A1 (en) 2013-08-30 2014-09-01 Means and methods for diagnosing heart failure in a subject

Publications (2)

Publication Number Publication Date
JP2016532115A true JP2016532115A (ja) 2016-10-13
JP2016532115A5 JP2016532115A5 (enExample) 2017-10-12

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JP2016537328A Ceased JP2016532115A (ja) 2013-08-30 2014-09-01 被験体において心不全を診断するための手段及び方法

Country Status (5)

Country Link
US (1) US20160209433A1 (enExample)
EP (1) EP3039430A1 (enExample)
JP (1) JP2016532115A (enExample)
CA (1) CA2922331A1 (enExample)
WO (1) WO2015028671A1 (enExample)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BR112012018771A2 (pt) * 2010-01-29 2017-06-20 Metanomics Gmbh ''método para dianosticar insuficência cardíaca em um sujeito''
JP2017523417A (ja) * 2014-07-28 2017-08-17 メタノミクス ゲーエムベーハー コレステロールパラメータ、スフィンゴミエリンおよび/またはトリアシルグリセロールに基づいて心不全を診断するための手段および方法
US20170285049A1 (en) * 2014-09-01 2017-10-05 Metanomics Gmbh Means and Methods for Diagnosing Heart Failure in a Subject
US20180238914A1 (en) * 2015-08-19 2018-08-23 Metanomics Gmbh Means and methods for diagnosing cardiac disease in a subject
KR102362234B1 (ko) * 2016-03-09 2022-02-11 씨비메드 게엠베하 센터 포 바이오마커 리서치 인 메디슨 폐고혈압 (ph)의 진단을 위한 바이오마커
CN115112776B (zh) * 2021-03-18 2023-07-04 中国科学院大连化学物理研究所 联合标志物及在诊断心房颤动中应用及诊断试剂或试剂盒

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2006526140A (ja) * 2002-12-24 2006-11-16 バイオサイト インコーポレイテッド 鑑別診断のためのマーカーおよびその使用方法
WO2011092285A2 (en) * 2010-01-29 2011-08-04 Metanomics Gmbh Means and methods for diagnosing heart failure in a subject
WO2013014286A2 (en) * 2011-07-28 2013-01-31 Metanomics Gmbh Means and methods for diagnosing and monitoring heart failure in a subject

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2006526140A (ja) * 2002-12-24 2006-11-16 バイオサイト インコーポレイテッド 鑑別診断のためのマーカーおよびその使用方法
WO2011092285A2 (en) * 2010-01-29 2011-08-04 Metanomics Gmbh Means and methods for diagnosing heart failure in a subject
JP2013518271A (ja) * 2010-01-29 2013-05-20 メタノミクス ゲーエムベーハー 被験体において心不全を診断するための手段及び方法
WO2013014286A2 (en) * 2011-07-28 2013-01-31 Metanomics Gmbh Means and methods for diagnosing and monitoring heart failure in a subject

Also Published As

Publication number Publication date
CA2922331A1 (en) 2015-03-05
WO2015028671A1 (en) 2015-03-05
EP3039430A1 (en) 2016-07-06
US20160209433A1 (en) 2016-07-21

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