CA2922331A1 - Means and methods for diagnosing heart failure in a subject - Google Patents

Means and methods for diagnosing heart failure in a subject Download PDF

Info

Publication number
CA2922331A1
CA2922331A1 CA2922331A CA2922331A CA2922331A1 CA 2922331 A1 CA2922331 A1 CA 2922331A1 CA 2922331 A CA2922331 A CA 2922331A CA 2922331 A CA2922331 A CA 2922331A CA 2922331 A1 CA2922331 A1 CA 2922331A1
Authority
CA
Canada
Prior art keywords
sphingomyelin
cholesterylester
group
heart failure
cysteine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA2922331A
Other languages
English (en)
French (fr)
Inventor
Henning Witt
Jurgen Kastler
Bianca Bethan
Erik Peter
Philipp Schatz
Hans Dirk DUENGEN
Tobias Daniel TRIPPEL
Elvis TAHIROVIC
Tanja Weis
Hugo A. Katus
Norbert Frey
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Universität Heidelberg
BASF Metabolome Solutions GmbH
Original Assignee
Universität Heidelberg
Metanomics GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Universität Heidelberg, Metanomics GmbH filed Critical Universität Heidelberg
Publication of CA2922331A1 publication Critical patent/CA2922331A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/92—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving lipids, e.g. cholesterol, lipoproteins, or their receptors
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B50/00—ICT programming tools or database systems specially adapted for bioinformatics
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2405/00—Assays, e.g. immunoassays or enzyme assays, involving lipids
    • G01N2405/08—Sphingolipids
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2560/00—Chemical aspects of mass spectrometric analysis of biological material
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2570/00—Omics, e.g. proteomics, glycomics or lipidomics; Methods of analysis focusing on the entire complement of classes of biological molecules or subsets thereof, i.e. focusing on proteomes, glycomes or lipidomes
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/32—Cardiovascular disorders
    • G01N2800/325—Heart failure or cardiac arrest, e.g. cardiomyopathy, congestive heart failure

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Physics & Mathematics (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Immunology (AREA)
  • Hematology (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Cell Biology (AREA)
  • Analytical Chemistry (AREA)
  • Biophysics (AREA)
  • Microbiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Databases & Information Systems (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Bioethics (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Evolutionary Biology (AREA)
  • Medical Informatics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Theoretical Computer Science (AREA)
  • Endocrinology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
CA2922331A 2013-08-30 2014-09-01 Means and methods for diagnosing heart failure in a subject Abandoned CA2922331A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP13182441.9 2013-08-30
EP13182441 2013-08-30
PCT/EP2014/068530 WO2015028671A1 (en) 2013-08-30 2014-09-01 Means and methods for diagnosing heart failure in a subject

Publications (1)

Publication Number Publication Date
CA2922331A1 true CA2922331A1 (en) 2015-03-05

Family

ID=49036531

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2922331A Abandoned CA2922331A1 (en) 2013-08-30 2014-09-01 Means and methods for diagnosing heart failure in a subject

Country Status (5)

Country Link
US (1) US20160209433A1 (enExample)
EP (1) EP3039430A1 (enExample)
JP (1) JP2016532115A (enExample)
CA (1) CA2922331A1 (enExample)
WO (1) WO2015028671A1 (enExample)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9285378B2 (en) * 2010-01-29 2016-03-15 Metanomics Gmbh Means and methods for diagnosing heart failure in a subject
JP2017523417A (ja) * 2014-07-28 2017-08-17 メタノミクス ゲーエムベーハー コレステロールパラメータ、スフィンゴミエリンおよび／またはトリアシルグリセロールに基づいて心不全を診断するための手段および方法
WO2016034600A1 (en) * 2014-09-01 2016-03-10 Metanomics Gmbh Means and methods for diagnosing heart failure in a subject
WO2017029401A1 (en) * 2015-08-19 2017-02-23 Metanomics Gmbh Means and methods for diagnosing cardiac disease in a subject
US11275093B2 (en) * 2016-03-09 2022-03-15 Cbmed Gmbh Center For Biomarker Research In Medicine Biomarker for the diagnosis of pulmonary hypertension (PH)
CN115112776B (zh) * 2021-03-18 2023-07-04 中国科学院大连化学物理研究所 联合标志物及在诊断心房颤动中应用及诊断试剂或试剂盒

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2006526140A (ja) * 2002-12-24 2006-11-16 バイオサイト インコーポレイテッド 鑑別診断のためのマーカーおよびその使用方法
US9285378B2 (en) * 2010-01-29 2016-03-15 Metanomics Gmbh Means and methods for diagnosing heart failure in a subject
AU2012288742B2 (en) * 2011-07-28 2016-12-08 Ruprecht-Karls-Universitaet Heidelberg Means and methods for diagnosing and monitoring heart failure in a subject

Also Published As

Publication number Publication date
EP3039430A1 (en) 2016-07-06
JP2016532115A (ja) 2016-10-13
WO2015028671A1 (en) 2015-03-05
US20160209433A1 (en) 2016-07-21

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Legal Events

Date Code Title Description
FZDE Discontinued

Effective date: 20200903