JP2016529223A5 - - Google Patents
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- Publication number
- JP2016529223A5 JP2016529223A5 JP2016523852A JP2016523852A JP2016529223A5 JP 2016529223 A5 JP2016529223 A5 JP 2016529223A5 JP 2016523852 A JP2016523852 A JP 2016523852A JP 2016523852 A JP2016523852 A JP 2016523852A JP 2016529223 A5 JP2016529223 A5 JP 2016529223A5
- Authority
- JP
- Japan
- Prior art keywords
- rv1733c
- mtb
- rv2626c
- mtb antigen
- vector
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000000427 antigen Substances 0.000 claims 30
- 102000036639 antigens Human genes 0.000 claims 30
- 108091007433 antigens Proteins 0.000 claims 30
- 101100103958 Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) Rv1733c gene Proteins 0.000 claims 13
- 239000013598 vector Substances 0.000 claims 13
- 239000000203 mixture Substances 0.000 claims 12
- 108020001507 fusion proteins Proteins 0.000 claims 11
- 102000037865 fusion proteins Human genes 0.000 claims 11
- 241001217856 Chimpanzee adenovirus Species 0.000 claims 9
- 101100395578 Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) hrp1 gene Proteins 0.000 claims 9
- 208000002606 Paramyxoviridae Infections Diseases 0.000 claims 6
- 241000700605 Viruses Species 0.000 claims 6
- 101710088334 Diacylglycerol acyltransferase/mycolyltransferase Ag85B Proteins 0.000 claims 4
- -1 ESAT6 Proteins 0.000 claims 4
- 241000187479 Mycobacterium tuberculosis Species 0.000 claims 4
- 101100156500 Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) vapB47 gene Proteins 0.000 claims 4
- 101150053438 PPE51 gene Proteins 0.000 claims 4
- 230000001154 acute effect Effects 0.000 claims 4
- 239000003814 drug Substances 0.000 claims 4
- 241001135569 Human adenovirus 5 Species 0.000 claims 3
- 241001135572 Human adenovirus E4 Species 0.000 claims 3
- 206010046865 Vaccinia virus infection Diseases 0.000 claims 3
- 208000007089 vaccinia Diseases 0.000 claims 3
- 239000013603 viral vector Substances 0.000 claims 3
- 101100445609 Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) espC gene Proteins 0.000 claims 2
- 101150082852 PPE15 gene Proteins 0.000 claims 2
- 239000000443 aerosol Substances 0.000 claims 2
- 101150014428 mpt64 gene Proteins 0.000 claims 2
- 230000002265 prevention Effects 0.000 claims 2
- 201000008827 tuberculosis Diseases 0.000 claims 2
- 239000013604 expression vector Substances 0.000 claims 1
- 102000039446 nucleic acids Human genes 0.000 claims 1
- 108020004707 nucleic acids Proteins 0.000 claims 1
- 150000007523 nucleic acids Chemical class 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361838872P | 2013-06-25 | 2013-06-25 | |
| US61/838,872 | 2013-06-25 | ||
| PCT/US2014/043889 WO2014210018A1 (en) | 2013-06-25 | 2014-06-24 | Tuberculosis compositions and methods of using the same |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019124873A Division JP7269806B2 (ja) | 2013-06-25 | 2019-07-04 | 結核組成物及びそれを使用する方法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2016529223A JP2016529223A (ja) | 2016-09-23 |
| JP2016529223A5 true JP2016529223A5 (https=) | 2017-08-03 |
| JP6554095B2 JP6554095B2 (ja) | 2019-07-31 |
Family
ID=52111114
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016523852A Active JP6554095B2 (ja) | 2013-06-25 | 2014-06-24 | 結核組成物及びそれを使用する方法 |
| JP2019124873A Active JP7269806B2 (ja) | 2013-06-25 | 2019-07-04 | 結核組成物及びそれを使用する方法 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019124873A Active JP7269806B2 (ja) | 2013-06-25 | 2019-07-04 | 結核組成物及びそれを使用する方法 |
Country Status (7)
| Country | Link |
|---|---|
| US (4) | US10266574B2 (https=) |
| EP (2) | EP3013364B1 (https=) |
| JP (2) | JP6554095B2 (https=) |
| CN (1) | CN105431166B (https=) |
| ES (1) | ES2925950T3 (https=) |
| WO (1) | WO2014210018A1 (https=) |
| ZA (1) | ZA201509262B (https=) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TWI638829B (zh) * | 2012-07-10 | 2018-10-21 | 法商傳斯堅公司 | 分枝桿菌抗原疫苗 |
| ES2925950T3 (es) | 2013-06-25 | 2022-10-20 | Int Aids Vaccine Initiative Inc | Composiciones para la tuberculosis y procedimientos de uso de las mismas |
| WO2015104380A1 (en) * | 2014-01-09 | 2015-07-16 | Transgene Sa | Fusion of heterooligomeric mycobacterial antigens |
| WO2016120489A2 (en) * | 2015-02-01 | 2016-08-04 | Theravectys | Lentiviral vectors for expression of mycobacterium tuberculosis antigens |
| AU2017285424B2 (en) * | 2016-06-16 | 2022-08-18 | International Aids Vaccine Initiative, Inc. | Tuberculosis compositions and methods of treating or preventing tuberculosis |
| CN109843321A (zh) * | 2016-06-22 | 2019-06-04 | 国际艾滋病疫苗行动组织公司 | 作为结核病疫苗的重组巨细胞病毒载体 |
| US10684275B2 (en) | 2016-12-14 | 2020-06-16 | Becton, Dickinson And Company | Methods and compositions for obtaining a tuberculosis assessment in a subject |
| CN108239660B (zh) * | 2016-12-26 | 2021-08-10 | 上海生物制品研究所有限责任公司 | 一种重组结核病疫苗，其制备方法及应用 |
| WO2018236876A2 (en) * | 2017-06-19 | 2018-12-27 | Washington University | Nanoemulsion and methods of use thereof |
| WO2019079155A1 (en) | 2017-10-17 | 2019-04-25 | International Aids Vaccine Initiative, Inc. | CASSETTES OF ANTIGENS OF TUBERCULOSIS |
| KR102135334B1 (ko) * | 2018-12-19 | 2020-07-17 | 대한민국 | 결핵 다가 항원을 발현하는 재조합 아데노 바이러스 및 이를 포함하는 결핵 예방용 조성물 |
| CN116327906B (zh) * | 2021-12-22 | 2026-03-20 | 中国人民解放军总医院第八医学中心 | 一种结核分枝杆菌串联dna疫苗w545及其制备方法与应用 |
| CN116655754A (zh) * | 2023-03-31 | 2023-08-29 | 中国疾病预防控制中心传染病预防控制所 | 一种抗原组合物及其应用 |
| CN117777259B (zh) * | 2024-02-23 | 2024-06-07 | 上海科新生物技术股份有限公司 | 检测结核感染的抗原组合物、试剂盒及其应用 |
Family Cites Families (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US21579A (en) | 1858-09-21 | Rotary valve fob steam-engines | ||
| EP0646178A1 (en) | 1992-06-04 | 1995-04-05 | The Regents Of The University Of California | expression cassette with regularoty regions functional in the mammmlian host |
| US5593972A (en) | 1993-01-26 | 1997-01-14 | The Wistar Institute | Genetic immunization |
| HU219767B (hu) | 1993-01-26 | 2001-07-30 | Leslie R. Coney | Készítmények és eljárások genetikai anyag sejtbe történő beviteléhez |
| US5962428A (en) | 1995-03-30 | 1999-10-05 | Apollon, Inc. | Compositions and methods for delivery of genetic material |
| US20100047286A1 (en) | 2004-12-01 | 2010-02-25 | Aeras Global Tb Vaccine Foundation | Recombinant BCG strains with enhanced ability to escape the endosome |
| BRPI0612833A2 (pt) | 2005-06-23 | 2010-11-30 | Statens Seruminstitut | composição imunogênica, vacina, composição farmacêutica, polipeptìdeo de fusão e uso das três primeiras |
| EP1962910A4 (en) * | 2005-12-15 | 2010-03-31 | Aeras Global Tb Vaccine Found | Novel prime-boost combinations of attenuated mycobacterium |
| BRPI0809926B8 (pt) * | 2007-04-04 | 2021-05-25 | Infectious Disease Res Inst | composição que compreende antígenos de mycobacterium tuberculosis, polipeptídeo de fusão isolado, polinucleotídeo isolado que codifica o dito polipeptídeo e uso da dita composição para estimular uma resposta imune protetora |
| US8361482B2 (en) | 2007-11-27 | 2013-01-29 | Aeras Global Tb Vaccine Foundation | Recombinant BCG tuberculosis vaccine designed to elicit immune responses to mycobacterium tuberculosis in all physiological stages of infection and disease |
| US7670609B2 (en) * | 2007-11-27 | 2010-03-02 | Aeras Global Tb Vaccine Foundation | Recombinant BCG tuberculosis vaccine designed to elicit immune responses to Mycobacterium tuberculosis in all physiological stages of infection and disease |
| CN101289496B (zh) * | 2008-05-30 | 2011-06-29 | 中国医学科学院医学生物学研究所 | 能激发机体抗结核杆菌的保护性免疫反应的抗原表位筛选方法及用途 |
| BRPI1011902A2 (pt) * | 2009-04-28 | 2019-09-24 | Univ Johns Hopkins | composições e métodos para potencialização de respostas imunes antígeno-específicas |
| GB0918154D0 (en) * | 2009-10-16 | 2009-12-02 | Isis Innovation | Mycobacterial vaccines |
| US20120219582A1 (en) * | 2009-11-02 | 2012-08-30 | Mie University | Intranasal spray-type tuberculosis vaccine using paramyxovirus vector |
| BR112012018669A2 (pt) * | 2010-01-27 | 2017-09-05 | Glaxosmithkline Biologicals Sa | Proteína rv3616c modificada, uso de uma proteína rv3616c modificada, polinucleotídeo, uso de um polinucleotídeo, composição farmacêutica, composição imunogênica, proteína de fusão, e, polipeptídeo. |
| US20120003256A1 (en) | 2010-03-01 | 2012-01-05 | Huiling Han | Tuberculosis antigens, immunogenic compositions, diagnostics and methods related to the same |
| GB201008512D0 (en) * | 2010-05-21 | 2010-07-07 | Health Prot Agency | Mycobacterial antigen composition |
| TWI638829B (zh) * | 2012-07-10 | 2018-10-21 | 法商傳斯堅公司 | 分枝桿菌抗原疫苗 |
| ES2925950T3 (es) | 2013-06-25 | 2022-10-20 | Int Aids Vaccine Initiative Inc | Composiciones para la tuberculosis y procedimientos de uso de las mismas |
| CN104474538A (zh) | 2014-08-13 | 2015-04-01 | 华中科技大学 | 一种重组卡介苗 |
-
2014
- 2014-06-24 ES ES14817274T patent/ES2925950T3/es active Active
- 2014-06-24 US US14/313,694 patent/US10266574B2/en active Active
- 2014-06-24 EP EP14817274.5A patent/EP3013364B1/en active Active
- 2014-06-24 WO PCT/US2014/043889 patent/WO2014210018A1/en not_active Ceased
- 2014-06-24 CN CN201480040735.5A patent/CN105431166B/zh active Active
- 2014-06-24 EP EP22188098.2A patent/EP4176897A1/en active Pending
- 2014-06-24 JP JP2016523852A patent/JP6554095B2/ja active Active
-
2015
- 2015-12-18 ZA ZA2015/09262A patent/ZA201509262B/en unknown
-
2019
- 2019-03-01 US US16/289,919 patent/US11014969B2/en active Active
- 2019-07-04 JP JP2019124873A patent/JP7269806B2/ja active Active
-
2021
- 2021-04-21 US US17/236,409 patent/US11787842B2/en active Active
-
2023
- 2023-09-06 US US18/461,754 patent/US20240101612A1/en active Pending
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