JP2016527481A5 - - Google Patents
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- Publication number
- JP2016527481A5 JP2016527481A5 JP2016518523A JP2016518523A JP2016527481A5 JP 2016527481 A5 JP2016527481 A5 JP 2016527481A5 JP 2016518523 A JP2016518523 A JP 2016518523A JP 2016518523 A JP2016518523 A JP 2016518523A JP 2016527481 A5 JP2016527481 A5 JP 2016527481A5
- Authority
- JP
- Japan
- Prior art keywords
- atom
- theta
- iota
- ligand
- atoms
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB1310544.0 | 2013-06-13 | ||
| GBGB1310544.0A GB201310544D0 (en) | 2013-06-13 | 2013-06-13 | Obtaining an improved therapeutic ligand |
| PCT/EP2014/062478 WO2014198951A2 (en) | 2013-06-13 | 2014-06-13 | Obtaining an improved therapeutic ligand |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2016527481A JP2016527481A (ja) | 2016-09-08 |
| JP2016527481A5 true JP2016527481A5 (https=) | 2017-07-20 |
| JP6484612B2 JP6484612B2 (ja) | 2019-03-13 |
Family
ID=48914497
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016518523A Active JP6484612B2 (ja) | 2013-06-13 | 2014-06-13 | 改善された治療リガンドの取得 |
Country Status (15)
| Country | Link |
|---|---|
| US (2) | US20160125124A1 (https=) |
| EP (1) | EP3008648B1 (https=) |
| JP (1) | JP6484612B2 (https=) |
| KR (1) | KR20160019504A (https=) |
| CN (1) | CN105308602B (https=) |
| AU (1) | AU2014280055A1 (https=) |
| BR (1) | BR112015031171A2 (https=) |
| CA (1) | CA2914726A1 (https=) |
| CL (1) | CL2015003591A1 (https=) |
| GB (1) | GB201310544D0 (https=) |
| HK (1) | HK1218579A1 (https=) |
| MX (1) | MX2015016822A (https=) |
| RU (1) | RU2016100234A (https=) |
| SG (2) | SG11201510084TA (https=) |
| WO (1) | WO2014198951A2 (https=) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL296732A (en) | 2020-03-27 | 2022-11-01 | UCB Biopharma SRL | Autonomous knob domain peptides |
| CN113380320B (zh) * | 2021-07-01 | 2022-03-15 | 中国海洋大学 | 基于阳性化合物残基贡献相似度的分子对接结果筛选方法 |
| CN115708166A (zh) * | 2021-08-20 | 2023-02-21 | 北京望石智慧科技有限公司 | 一种药物分子设计方法、装置、电子设备及存储介质 |
| CN114530215B (zh) * | 2022-02-18 | 2023-03-28 | 北京有竹居网络技术有限公司 | 设计配体分子的方法和装置 |
| CN115171774A (zh) * | 2022-05-17 | 2022-10-11 | 慧壹科技(上海)有限公司 | 一种抗体/大分子药物的亲和力改造系统和方法 |
| CN121712809A (zh) | 2023-07-03 | 2026-03-20 | Ucb生物制药有限责任公司 | 工程化的aav衣壳蛋白 |
| GB202314896D0 (en) | 2023-09-28 | 2023-11-15 | UCB Biopharma SRL | Knob domain proteins |
Family Cites Families (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5331573A (en) * | 1990-12-14 | 1994-07-19 | Balaji Vitukudi N | Method of design of compounds that mimic conformational features of selected peptides |
| US5642292A (en) | 1992-03-27 | 1997-06-24 | Akiko Itai | Methods for searching stable docking models of biopolymer-ligand molecule complex |
| GB0011818D0 (en) * | 2000-05-16 | 2000-07-05 | Inpharmatica Ltd | Lead molecule generation |
| US20020025535A1 (en) | 2000-06-15 | 2002-02-28 | Diller David J. | Prioritization of combinatorial library screening |
| AU2001279973A1 (en) | 2000-08-21 | 2002-03-04 | Ribotargets Limited | Computer-based modelling of ligand/receptor structures |
| JP2004511803A (ja) * | 2000-10-16 | 2004-04-15 | オーソ−マクニール・フアーマシユーチカル・インコーポレーテツド | バニロイド受容体についての改良リガンド結合アッセイ |
| AU2002246737B2 (en) * | 2000-12-29 | 2007-03-01 | Savient Pharmaceuticals, Inc. | Specific human antibodies for selective cancer therapy |
| US20030148391A1 (en) * | 2002-01-24 | 2003-08-07 | Salafsky Joshua S. | Method using a nonlinear optical technique for detection of interactions involving a conformational change |
| EP1620548A2 (en) | 2003-05-07 | 2006-02-01 | Duke University | Protein design for receptor-ligand recognition and binding |
| US20060105390A1 (en) * | 2003-10-29 | 2006-05-18 | Yi Zhang | Method of characterizing heterogeneity in receptor-ligand interactions and related method of assay signal histogram transformation |
| JP2005181104A (ja) * | 2003-12-19 | 2005-07-07 | Hitachi Ltd | 高精度ドッキングスコアリング方法 |
| JP4719223B2 (ja) | 2005-03-11 | 2011-07-06 | シュレディンガー エルエルシー | 結合親和性を推定するための予測的スコア関数 |
| GB0620729D0 (en) | 2006-10-18 | 2006-11-29 | Ucb Sa | Biological products |
| US20090006040A1 (en) | 2007-05-24 | 2009-01-01 | Peter Hrnciar | Systems and Methods for Representing Protein Binding Sites and Identifying Molecules with Biological Activity |
| EP2216429A4 (en) | 2007-11-12 | 2011-06-15 | In Silico Sciences Inc | SILICO SCREENING SYSTEM AND SILICO SCREENING METHOD |
| GB0807413D0 (en) | 2008-04-23 | 2008-05-28 | Ucb Pharma Sa | Biological products |
| JPWO2010110288A1 (ja) * | 2009-03-24 | 2012-09-27 | 株式会社カネカ | 免疫グロブリンに親和性を有するタンパク質および免疫グロブリン結合性アフィニティーリガンド |
| US9023876B2 (en) * | 2010-07-08 | 2015-05-05 | Adhaere Pharmaceuticals, Inc. | Compounds and methods for regulating integrins |
| ME02734B (me) | 2011-01-14 | 2017-10-20 | Ucb Biopharma Sprl | Antitelo koje vezuje il-17a i il-17f |
-
2013
- 2013-06-13 GB GBGB1310544.0A patent/GB201310544D0/en not_active Ceased
-
2014
- 2014-06-13 SG SG11201510084TA patent/SG11201510084TA/en unknown
- 2014-06-13 WO PCT/EP2014/062478 patent/WO2014198951A2/en not_active Ceased
- 2014-06-13 JP JP2016518523A patent/JP6484612B2/ja active Active
- 2014-06-13 SG SG10201707917UA patent/SG10201707917UA/en unknown
- 2014-06-13 AU AU2014280055A patent/AU2014280055A1/en not_active Abandoned
- 2014-06-13 CN CN201480033334.7A patent/CN105308602B/zh active Active
- 2014-06-13 HK HK16106512.8A patent/HK1218579A1/zh unknown
- 2014-06-13 BR BR112015031171A patent/BR112015031171A2/pt not_active IP Right Cessation
- 2014-06-13 MX MX2015016822A patent/MX2015016822A/es unknown
- 2014-06-13 KR KR1020167000533A patent/KR20160019504A/ko not_active Withdrawn
- 2014-06-13 US US14/897,459 patent/US20160125124A1/en not_active Abandoned
- 2014-06-13 EP EP14729693.3A patent/EP3008648B1/en active Active
- 2014-06-13 RU RU2016100234A patent/RU2016100234A/ru not_active Application Discontinuation
- 2014-06-13 CA CA2914726A patent/CA2914726A1/en not_active Abandoned
-
2015
- 2015-12-10 CL CL2015003591A patent/CL2015003591A1/es unknown
-
2020
- 2020-03-18 US US16/823,055 patent/US11942188B2/en active Active
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