GB201310544D0 - Obtaining an improved therapeutic ligand - Google Patents

Obtaining an improved therapeutic ligand

Info

Publication number
GB201310544D0
GB201310544D0 GBGB1310544.0A GB201310544A GB201310544D0 GB 201310544 D0 GB201310544 D0 GB 201310544D0 GB 201310544 A GB201310544 A GB 201310544A GB 201310544 D0 GB201310544 D0 GB 201310544D0
Authority
GB
United Kingdom
Prior art keywords
obtaining
improved therapeutic
therapeutic ligand
ligand
improved
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
GBGB1310544.0A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
UCB Biopharma SRL
Original Assignee
UCB SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by UCB SA filed Critical UCB SA
Priority to GBGB1310544.0A priority Critical patent/GB201310544D0/en
Publication of GB201310544D0 publication Critical patent/GB201310544D0/en
Priority to PCT/EP2014/062478 priority patent/WO2014198951A2/en
Priority to SG10201707917UA priority patent/SG10201707917UA/en
Priority to MX2015016822A priority patent/MX2015016822A/es
Priority to SG11201510084TA priority patent/SG11201510084TA/en
Priority to CA2914726A priority patent/CA2914726A1/en
Priority to EP14729693.3A priority patent/EP3008648B1/en
Priority to US14/897,459 priority patent/US20160125124A1/en
Priority to KR1020167000533A priority patent/KR20160019504A/ko
Priority to BR112015031171A priority patent/BR112015031171A2/pt
Priority to CN201480033334.7A priority patent/CN105308602B/zh
Priority to HK16106512.8A priority patent/HK1218579A1/zh
Priority to AU2014280055A priority patent/AU2014280055A1/en
Priority to JP2016518523A priority patent/JP6484612B2/ja
Priority to RU2016100234A priority patent/RU2016100234A/ru
Priority to CL2015003591A priority patent/CL2015003591A1/es
Priority to US16/823,055 priority patent/US11942188B2/en
Ceased legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B5/00—ICT specially adapted for modelling or simulations in systems biology, e.g. gene-regulatory networks, protein interaction networks or metabolic networks
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C07K16/244—Interleukins [IL]
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B15/00—ICT specially adapted for analysing two-dimensional [2D] or three-dimensional [3D] molecular structures, e.g. structural or functional relations or structure alignment
    • G16B15/30—Drug targeting using structural data; Docking or binding prediction
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16C—COMPUTATIONAL CHEMISTRY; CHEMOINFORMATICS; COMPUTATIONAL MATERIALS SCIENCE
    • G16C20/00—Chemoinformatics, i.e. ICT specially adapted for the handling of physicochemical or structural data of chemical particles, elements, compounds or mixtures
    • G16C20/50—Molecular design, e.g. of drugs
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16C—COMPUTATIONAL CHEMISTRY; CHEMOINFORMATICS; COMPUTATIONAL MATERIALS SCIENCE
    • G16C20/00—Chemoinformatics, i.e. ICT specially adapted for the handling of physicochemical or structural data of chemical particles, elements, compounds or mixtures
    • G16C20/90—Programming languages; Computing architectures; Database systems; Data warehousing
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/55—Fab or Fab'
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B15/00—ICT specially adapted for analysing two-dimensional [2D] or three-dimensional [3D] molecular structures, e.g. structural or functional relations or structure alignment
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A90/00—Technologies having an indirect contribution to adaptation to climate change
    • Y02A90/10—Information and communication technologies [ICT] supporting adaptation to climate change, e.g. for weather forecasting or climate simulation

Landscapes

  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Theoretical Computer Science (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Biophysics (AREA)
  • Medicinal Chemistry (AREA)
  • Computing Systems (AREA)
  • Evolutionary Biology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medical Informatics (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Physiology (AREA)
  • Organic Chemistry (AREA)
  • Databases & Information Systems (AREA)
  • Software Systems (AREA)
  • Immunology (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Information Retrieval, Db Structures And Fs Structures Therefor (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Steroid Compounds (AREA)
GBGB1310544.0A 2013-06-13 2013-06-13 Obtaining an improved therapeutic ligand Ceased GB201310544D0 (en)

Priority Applications (17)

Application Number Priority Date Filing Date Title
GBGB1310544.0A GB201310544D0 (en) 2013-06-13 2013-06-13 Obtaining an improved therapeutic ligand
RU2016100234A RU2016100234A (ru) 2013-06-13 2014-06-13 Получение терапевтического лиганда с улучшенными свойствами
KR1020167000533A KR20160019504A (ko) 2013-06-13 2014-06-13 개선된 치료용 리간드 획득
CN201480033334.7A CN105308602B (zh) 2013-06-13 2014-06-13 获得改善的治疗性配体的方法及由此获得的治疗性配体
MX2015016822A MX2015016822A (es) 2013-06-13 2014-06-13 Obtencion de un ligando terapeutico mejorado.
SG11201510084TA SG11201510084TA (en) 2013-06-13 2014-06-13 Obtaining an improved therapeutic ligand
CA2914726A CA2914726A1 (en) 2013-06-13 2014-06-13 Obtaining an improved therapeutic ligand
EP14729693.3A EP3008648B1 (en) 2013-06-13 2014-06-13 Obtaining an improved therapeutic ligand
US14/897,459 US20160125124A1 (en) 2013-06-13 2014-06-13 Obtaining an Improved Therapeutic Ligand
PCT/EP2014/062478 WO2014198951A2 (en) 2013-06-13 2014-06-13 Obtaining an improved therapeutic ligand
BR112015031171A BR112015031171A2 (pt) 2013-06-13 2014-06-13 obtenção de um ligante terapêutico melhorado
SG10201707917UA SG10201707917UA (en) 2013-06-13 2014-06-13 Obtaining an improved therapeutic ligand
HK16106512.8A HK1218579A1 (zh) 2013-06-13 2014-06-13 获得改善的治疗性配体
AU2014280055A AU2014280055A1 (en) 2013-06-13 2014-06-13 Obtaining an improved therapeutic ligand
JP2016518523A JP6484612B2 (ja) 2013-06-13 2014-06-13 改善された治療リガンドの取得
CL2015003591A CL2015003591A1 (es) 2013-06-13 2015-12-10 Obtención de un ligando terapéutico mejorado
US16/823,055 US11942188B2 (en) 2013-06-13 2020-03-18 Obtaining an improved therapeutic ligand

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB1310544.0A GB201310544D0 (en) 2013-06-13 2013-06-13 Obtaining an improved therapeutic ligand

Publications (1)

Publication Number Publication Date
GB201310544D0 true GB201310544D0 (en) 2013-07-31

Family

ID=48914497

Family Applications (1)

Application Number Title Priority Date Filing Date
GBGB1310544.0A Ceased GB201310544D0 (en) 2013-06-13 2013-06-13 Obtaining an improved therapeutic ligand

Country Status (15)

Country Link
US (2) US20160125124A1 (https=)
EP (1) EP3008648B1 (https=)
JP (1) JP6484612B2 (https=)
KR (1) KR20160019504A (https=)
CN (1) CN105308602B (https=)
AU (1) AU2014280055A1 (https=)
BR (1) BR112015031171A2 (https=)
CA (1) CA2914726A1 (https=)
CL (1) CL2015003591A1 (https=)
GB (1) GB201310544D0 (https=)
HK (1) HK1218579A1 (https=)
MX (1) MX2015016822A (https=)
RU (1) RU2016100234A (https=)
SG (2) SG11201510084TA (https=)
WO (1) WO2014198951A2 (https=)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL296732A (en) 2020-03-27 2022-11-01 UCB Biopharma SRL Autonomous knob domain peptides
CN113380320B (zh) * 2021-07-01 2022-03-15 中国海洋大学 基于阳性化合物残基贡献相似度的分子对接结果筛选方法
CN115708166A (zh) * 2021-08-20 2023-02-21 北京望石智慧科技有限公司 一种药物分子设计方法、装置、电子设备及存储介质
CN114530215B (zh) * 2022-02-18 2023-03-28 北京有竹居网络技术有限公司 设计配体分子的方法和装置
CN115171774A (zh) * 2022-05-17 2022-10-11 慧壹科技(上海)有限公司 一种抗体/大分子药物的亲和力改造系统和方法
CN121712809A (zh) 2023-07-03 2026-03-20 Ucb生物制药有限责任公司 工程化的aav衣壳蛋白
GB202314896D0 (en) 2023-09-28 2023-11-15 UCB Biopharma SRL Knob domain proteins

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5331573A (en) * 1990-12-14 1994-07-19 Balaji Vitukudi N Method of design of compounds that mimic conformational features of selected peptides
US5642292A (en) 1992-03-27 1997-06-24 Akiko Itai Methods for searching stable docking models of biopolymer-ligand molecule complex
GB0011818D0 (en) * 2000-05-16 2000-07-05 Inpharmatica Ltd Lead molecule generation
US20020025535A1 (en) 2000-06-15 2002-02-28 Diller David J. Prioritization of combinatorial library screening
AU2001279973A1 (en) 2000-08-21 2002-03-04 Ribotargets Limited Computer-based modelling of ligand/receptor structures
JP2004511803A (ja) * 2000-10-16 2004-04-15 オーソ−マクニール・フアーマシユーチカル・インコーポレーテツド バニロイド受容体についての改良リガンド結合アッセイ
AU2002246737B2 (en) * 2000-12-29 2007-03-01 Savient Pharmaceuticals, Inc. Specific human antibodies for selective cancer therapy
US20030148391A1 (en) * 2002-01-24 2003-08-07 Salafsky Joshua S. Method using a nonlinear optical technique for detection of interactions involving a conformational change
EP1620548A2 (en) 2003-05-07 2006-02-01 Duke University Protein design for receptor-ligand recognition and binding
US20060105390A1 (en) * 2003-10-29 2006-05-18 Yi Zhang Method of characterizing heterogeneity in receptor-ligand interactions and related method of assay signal histogram transformation
JP2005181104A (ja) * 2003-12-19 2005-07-07 Hitachi Ltd 高精度ドッキングスコアリング方法
JP4719223B2 (ja) 2005-03-11 2011-07-06 シュレディンガー エルエルシー 結合親和性を推定するための予測的スコア関数
GB0620729D0 (en) 2006-10-18 2006-11-29 Ucb Sa Biological products
US20090006040A1 (en) 2007-05-24 2009-01-01 Peter Hrnciar Systems and Methods for Representing Protein Binding Sites and Identifying Molecules with Biological Activity
EP2216429A4 (en) 2007-11-12 2011-06-15 In Silico Sciences Inc SILICO SCREENING SYSTEM AND SILICO SCREENING METHOD
GB0807413D0 (en) 2008-04-23 2008-05-28 Ucb Pharma Sa Biological products
JPWO2010110288A1 (ja) * 2009-03-24 2012-09-27 株式会社カネカ 免疫グロブリンに親和性を有するタンパク質および免疫グロブリン結合性アフィニティーリガンド
US9023876B2 (en) * 2010-07-08 2015-05-05 Adhaere Pharmaceuticals, Inc. Compounds and methods for regulating integrins
ME02734B (me) 2011-01-14 2017-10-20 Ucb Biopharma Sprl Antitelo koje vezuje il-17a i il-17f

Also Published As

Publication number Publication date
JP2016527481A (ja) 2016-09-08
CN105308602A (zh) 2016-02-03
CL2015003591A1 (es) 2016-08-05
EP3008648B1 (en) 2023-05-10
US20160125124A1 (en) 2016-05-05
RU2016100234A (ru) 2018-02-06
BR112015031171A2 (pt) 2017-07-25
RU2016100234A3 (https=) 2018-03-23
SG11201510084TA (en) 2016-01-28
CA2914726A1 (en) 2014-12-18
US20210005277A1 (en) 2021-01-07
JP6484612B2 (ja) 2019-03-13
EP3008648A2 (en) 2016-04-20
SG10201707917UA (en) 2017-10-30
MX2015016822A (es) 2016-04-13
WO2014198951A3 (en) 2015-08-27
CN105308602B (zh) 2019-09-27
AU2014280055A1 (en) 2016-01-28
HK1218579A1 (zh) 2017-02-24
US11942188B2 (en) 2024-03-26
WO2014198951A2 (en) 2014-12-18
KR20160019504A (ko) 2016-02-19

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Legal Events

Date Code Title Description
COOA Change in applicant's name or ownership of the application

Owner name: UCB BIOPHARMA SPRL

Free format text: FORMER OWNER: UCB PHARMA S.A.

AT Applications terminated before publication under section 16(1)