JP2016527199A5 - - Google Patents
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- JP2016527199A5 JP2016527199A5 JP2016518595A JP2016518595A JP2016527199A5 JP 2016527199 A5 JP2016527199 A5 JP 2016527199A5 JP 2016518595 A JP2016518595 A JP 2016518595A JP 2016518595 A JP2016518595 A JP 2016518595A JP 2016527199 A5 JP2016527199 A5 JP 2016527199A5
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Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2019019828A JP6942744B2 (ja) | 2013-06-11 | 2019-02-06 | 生物学的に活性な特異的カーゴペプチドと結合したヒト由来の細胞透過性ペプチドの構造、製造および使用 |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361833819P | 2013-06-11 | 2013-06-11 | |
| US61/833,819 | 2013-06-11 | ||
| PCT/IB2014/002029 WO2015025217A2 (en) | 2013-06-11 | 2014-06-11 | Structure, manufacturing and uses of human-derived cell-permeable peptides conjugated with specific biologically active cargo peptides |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019019828A Division JP6942744B2 (ja) | 2013-06-11 | 2019-02-06 | 生物学的に活性な特異的カーゴペプチドと結合したヒト由来の細胞透過性ペプチドの構造、製造および使用 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2016527199A JP2016527199A (ja) | 2016-09-08 |
| JP2016527199A5 true JP2016527199A5 (enExample) | 2017-07-20 |
| JP6479777B2 JP6479777B2 (ja) | 2019-03-06 |
Family
ID=52484225
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016518595A Expired - Fee Related JP6479777B2 (ja) | 2013-06-11 | 2014-06-11 | 生物学的に活性な特異的カーゴペプチドと結合したヒト由来の細胞透過性ペプチドの構造、製造および使用 |
| JP2019019828A Expired - Fee Related JP6942744B2 (ja) | 2013-06-11 | 2019-02-06 | 生物学的に活性な特異的カーゴペプチドと結合したヒト由来の細胞透過性ペプチドの構造、製造および使用 |
| JP2021146120A Pending JP2021193112A (ja) | 2013-06-11 | 2021-09-08 | 生物学的に活性な特異的カーゴペプチドと結合したヒト由来の細胞透過性ペプチドの構造、製造および使用 |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019019828A Expired - Fee Related JP6942744B2 (ja) | 2013-06-11 | 2019-02-06 | 生物学的に活性な特異的カーゴペプチドと結合したヒト由来の細胞透過性ペプチドの構造、製造および使用 |
| JP2021146120A Pending JP2021193112A (ja) | 2013-06-11 | 2021-09-08 | 生物学的に活性な特異的カーゴペプチドと結合したヒト由来の細胞透過性ペプチドの構造、製造および使用 |
Country Status (12)
| Country | Link |
|---|---|
| US (3) | US10301629B2 (enExample) |
| EP (2) | EP3007729B1 (enExample) |
| JP (3) | JP6479777B2 (enExample) |
| CN (1) | CN105555317A (enExample) |
| AU (3) | AU2014310360B2 (enExample) |
| CA (1) | CA2915296A1 (enExample) |
| DK (2) | DK3581207T5 (enExample) |
| ES (2) | ES2745566T3 (enExample) |
| HK (1) | HK1223838A1 (enExample) |
| MX (1) | MX2015016588A (enExample) |
| WO (1) | WO2015025217A2 (enExample) |
| ZA (1) | ZA201600162B (enExample) |
Families Citing this family (27)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2014310360B2 (en) * | 2013-06-11 | 2019-10-24 | PPL (BVI) Limited | Structure, manufacturing and uses of human-derived cell-permeable peptides conjugated with specific biologically active cargo peptides |
| HK1247933A1 (en) | 2015-06-24 | 2018-10-05 | Jcr Pharmaceuticals Co., Ltd. | Fusion protein containing bdnf |
| WO2017189826A1 (en) * | 2016-04-29 | 2017-11-02 | Portage Pharmaceuticals Ltd. | Use of cell-permeable peptides and non-peptide carriers conjugated with nemo binding domain cargo sequence for the treatment of dry eye disease and uveitis |
| AU2017358282C1 (en) * | 2016-11-09 | 2020-11-26 | Icm Co., Ltd. | Nkx3.2 fragment and pharmaceutical composition comprising same as active ingredient |
| TWI833178B (zh) | 2016-12-26 | 2024-02-21 | 日商Jcr製藥股份有限公司 | 通過血腦障壁之新穎抗人類運鐵蛋白受體抗體 |
| TWI791006B (zh) | 2016-12-26 | 2023-02-01 | 日商Jcr製藥股份有限公司 | 包含bdnf之融合蛋白質 |
| JP2020508289A (ja) * | 2017-01-31 | 2020-03-19 | レジェンクスバイオ インコーポレーテッド | 完全ヒトグリコシル化ヒトα−L−イズロニダーゼ(IDUA)を用いたムコ多糖症I型の治療 |
| CN107033217A (zh) * | 2017-03-29 | 2017-08-11 | 华中科技大学同济医学院附属协和医院 | 一种可抑制NF‑κB蛋白活化的多肽及检测sORF表达的方法 |
| CN107236023B (zh) * | 2017-05-12 | 2021-05-07 | 苏州创澜生物科技有限公司 | 一种用于检测结核感染的抗原组合物及其应用 |
| CN107227343A (zh) * | 2017-05-12 | 2017-10-03 | 苏州创澜生物科技有限公司 | 一种检测包含潜伏期结核感染的试剂盒及其引物对和探针 |
| CA3068328A1 (en) | 2017-07-06 | 2019-01-10 | The Trustees Of The University Of Pennsylvania | Aav9-mediated gene therapy for treating mucopolysaccharidosis type i |
| JP7727385B2 (ja) | 2017-12-18 | 2025-08-21 | ヴェンタナ メディカル システムズ, インク. | ペプチド核酸コンジュゲート |
| US11897924B2 (en) * | 2018-03-28 | 2024-02-13 | Bioxodes | Anticoagulant fusion proteins and uses thereof |
| EP3808840A4 (en) * | 2018-06-14 | 2022-03-23 | Avixgen Inc. | Pharmaceutical composition comprising fusion protein of cell-penetrating peptide and rpe65 for treatment of leber's congenital amaurosis |
| CN113227121A (zh) * | 2018-10-05 | 2021-08-06 | Rnagene公司 | 通过特异性结合至靶细胞具有增强的多种免疫功能的嵌合抗原及其用途 |
| US12115212B2 (en) * | 2019-01-18 | 2024-10-15 | L & J Bio Co., Ltd. | Methods of decreasing amyloid beta (Aβ) plaque deposition and hyperphosphorylated tau plaque deposition in Alzheimer's disease using a cystatin C fusion protein |
| CN113795575A (zh) | 2019-02-04 | 2021-12-14 | 自由行疗法有限公司 | 多核苷酸 |
| WO2020163771A1 (en) * | 2019-02-08 | 2020-08-13 | Portage Glasgow Limited | Structure, manufacturing and uses of hoxd12-pde8a cell-penetrating peptides |
| SG11202108812SA (en) * | 2019-02-15 | 2021-09-29 | Sigma Aldrich Co Llc | Crispr/cas fusion proteins and systems |
| WO2021072056A1 (en) * | 2019-10-08 | 2021-04-15 | Portage Glasgow Limited | P53 peptide disrupters of f0x04:p53 protein binding, variants and conjugates thereof. |
| BR112022017715A2 (pt) * | 2020-03-04 | 2022-11-16 | Flagship Pioneering Innovations Vi Llc | Métodos e composições para modular um genoma |
| JP7834290B2 (ja) * | 2020-12-22 | 2026-03-24 | 国立研究開発法人理化学研究所 | 医薬組成物 |
| US20240316217A1 (en) * | 2021-02-05 | 2024-09-26 | Regents Of The University Of Minnesota | Methods for preventing cardiac or skeletal defects in diseases including mucopolysaccharidoses |
| EP4308234A4 (en) * | 2021-03-16 | 2025-01-22 | Rush University Medical Center | METHODS OF TREATING NEURODEGENERATIVE DISEASES WITH PEPTIDE WITH INTRANASALE NF-KAPPAB ETHER TARGET MODIFIER (NEMO) BINDING DOMAIN (NBD) |
| WO2023056450A1 (en) * | 2021-09-30 | 2023-04-06 | Yale University | Compositions and methods for the treatment of autosomal dominant polycystic kidney disease and other diseases having upregulated mtor activity |
| CN114181318B (zh) * | 2021-11-08 | 2023-08-01 | 四川大学 | 一种组织特异性表达穿透血脑屏障的idua融合蛋白的重组腺相关病毒及应用 |
| WO2026080471A2 (en) | 2024-10-07 | 2026-04-16 | Flagship Pioneering Innovations Vi, Llc | Compositions of trem conjugates and uses thereof |
Family Cites Families (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR519558A (fr) | 1917-11-12 | 1921-06-11 | Carl Linde | Procédé de fabrication de cordes ou ficelles souples à l'aide de fils de papier |
| US5723315A (en) * | 1996-08-23 | 1998-03-03 | Genetics Institute, Inc. | Secreted proteins and polynucleotides encoding them |
| GB9718609D0 (en) * | 1997-09-02 | 1997-11-05 | Imp College Innovations Ltd | Fusion protein |
| US6669951B2 (en) * | 1999-08-24 | 2003-12-30 | Cellgate, Inc. | Compositions and methods for enhancing drug delivery across and into epithelial tissues |
| GB0015090D0 (en) * | 2000-06-20 | 2000-08-09 | Implyx Ltd | Gene-activating conjugates |
| US20040147027A1 (en) * | 2003-01-28 | 2004-07-29 | Troy Carol M. | Complex for facilitating delivery of dsRNA into a cell and uses thereof |
| US20060024331A1 (en) * | 2004-08-02 | 2006-02-02 | Ester Fernandez-Salas | Toxin compounds with enhanced membrane translocation characteristics |
| GB0507598D0 (en) * | 2005-04-14 | 2005-05-18 | Trojantec Technologies Ltd | Composition |
| WO2007056511A2 (en) * | 2005-11-09 | 2007-05-18 | Ontherix, Inc. | Metal-binding therapeutic peptides |
| US8470976B2 (en) * | 2006-06-17 | 2013-06-25 | Board Of Regents, The University Of Texas System | Methods and compositions for targeting macromolecules into the nucleus |
| JP2011519558A (ja) * | 2008-04-28 | 2011-07-14 | プレシジョン バイオサイエンシズ,インク. | 合理的に設計されたdna結合タンパク質とエフェクタードメインとの融合分子 |
| US20100190691A1 (en) | 2009-01-27 | 2010-07-29 | Trojan Technologies, Ltd | Delivery of nucleic acids using cell-penetrating peptides |
| KR101106262B1 (ko) * | 2009-09-07 | 2012-01-18 | 충남대학교산학협력단 | 인간 호메오 도메인 유전자 유래의 단백질 도입 도메인 및 이를 이용한 단백질 도입 벡터 |
| US9249184B2 (en) * | 2010-10-14 | 2016-02-02 | University of Pittsburgh—of the Commonwealth System of Higher Education | Cardiac-specific protein targeting domain |
| WO2013158819A2 (en) * | 2012-04-20 | 2013-10-24 | St. Jude Children's Research Hospital | Method for generation of conditionally immortalized hematopoietic progenitor cell lines with multiple lineage potential |
| AU2014310360B2 (en) * | 2013-06-11 | 2019-10-24 | PPL (BVI) Limited | Structure, manufacturing and uses of human-derived cell-permeable peptides conjugated with specific biologically active cargo peptides |
-
2014
- 2014-06-11 AU AU2014310360A patent/AU2014310360B2/en not_active Ceased
- 2014-06-11 JP JP2016518595A patent/JP6479777B2/ja not_active Expired - Fee Related
- 2014-06-11 DK DK19175082.7T patent/DK3581207T5/da active
- 2014-06-11 ES ES14838596T patent/ES2745566T3/es active Active
- 2014-06-11 MX MX2015016588A patent/MX2015016588A/es unknown
- 2014-06-11 EP EP14838596.6A patent/EP3007729B1/en active Active
- 2014-06-11 EP EP19175082.7A patent/EP3581207B1/en active Active
- 2014-06-11 CA CA2915296A patent/CA2915296A1/en not_active Abandoned
- 2014-06-11 CN CN201480033651.9A patent/CN105555317A/zh active Pending
- 2014-06-11 US US14/897,450 patent/US10301629B2/en active Active
- 2014-06-11 WO PCT/IB2014/002029 patent/WO2015025217A2/en not_active Ceased
- 2014-06-11 ES ES19175082T patent/ES2938758T3/es active Active
- 2014-06-11 HK HK16112193.2A patent/HK1223838A1/zh unknown
- 2014-06-11 DK DK14838596.6T patent/DK3007729T3/da active
-
2016
- 2016-01-08 ZA ZA2016/00162A patent/ZA201600162B/en unknown
-
2019
- 2019-02-06 US US16/268,814 patent/US10947539B2/en not_active Expired - Fee Related
- 2019-02-06 JP JP2019019828A patent/JP6942744B2/ja not_active Expired - Fee Related
-
2020
- 2020-01-22 AU AU2020200454A patent/AU2020200454A1/en not_active Abandoned
-
2021
- 2021-02-18 US US17/179,079 patent/US20210180069A1/en not_active Abandoned
- 2021-09-08 JP JP2021146120A patent/JP2021193112A/ja active Pending
-
2022
- 2022-04-01 AU AU2022202225A patent/AU2022202225A1/en not_active Abandoned
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