JP2016526050A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2016526050A5 JP2016526050A5 JP2016518053A JP2016518053A JP2016526050A5 JP 2016526050 A5 JP2016526050 A5 JP 2016526050A5 JP 2016518053 A JP2016518053 A JP 2016518053A JP 2016518053 A JP2016518053 A JP 2016518053A JP 2016526050 A5 JP2016526050 A5 JP 2016526050A5
- Authority
- JP
- Japan
- Prior art keywords
- level
- lyso
- spm
- therapeutic agent
- biological sample
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361832302P | 2013-06-07 | 2013-06-07 | |
| US61/832,302 | 2013-06-07 | ||
| PCT/US2014/041405 WO2014197859A1 (en) | 2013-06-07 | 2014-06-06 | Marker for acid sphingomyelinase disorders and uses thereof |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018236856A Division JP6835806B2 (ja) | 2013-06-07 | 2018-12-19 | 酸性スフィンゴミエリナーゼ障害のマーカーおよびその使用 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2016526050A JP2016526050A (ja) | 2016-09-01 |
| JP2016526050A5 true JP2016526050A5 (https=) | 2017-07-13 |
| JP6457501B2 JP6457501B2 (ja) | 2019-01-23 |
Family
ID=51062988
Family Applications (5)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016518053A Active JP6457501B2 (ja) | 2013-06-07 | 2014-06-06 | 酸性スフィンゴミエリナーゼ障害のマーカーおよびその使用 |
| JP2018236856A Active JP6835806B2 (ja) | 2013-06-07 | 2018-12-19 | 酸性スフィンゴミエリナーゼ障害のマーカーおよびその使用 |
| JP2021015390A Active JP7414750B2 (ja) | 2013-06-07 | 2021-02-03 | 酸性スフィンゴミエリナーゼ障害のマーカーおよびその使用 |
| JP2023220385A Active JP7830414B2 (ja) | 2013-06-07 | 2023-12-27 | 酸性スフィンゴミエリナーゼ障害のマーカーおよびその使用 |
| JP2025244095A Pending JP2026041958A (ja) | 2013-06-07 | 2025-12-10 | 酸性スフィンゴミエリナーゼ障害のマーカーおよびその使用 |
Family Applications After (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018236856A Active JP6835806B2 (ja) | 2013-06-07 | 2018-12-19 | 酸性スフィンゴミエリナーゼ障害のマーカーおよびその使用 |
| JP2021015390A Active JP7414750B2 (ja) | 2013-06-07 | 2021-02-03 | 酸性スフィンゴミエリナーゼ障害のマーカーおよびその使用 |
| JP2023220385A Active JP7830414B2 (ja) | 2013-06-07 | 2023-12-27 | 酸性スフィンゴミエリナーゼ障害のマーカーおよびその使用 |
| JP2025244095A Pending JP2026041958A (ja) | 2013-06-07 | 2025-12-10 | 酸性スフィンゴミエリナーゼ障害のマーカーおよびその使用 |
Country Status (29)
| Country | Link |
|---|---|
| US (4) | US10022428B2 (https=) |
| EP (2) | EP3584580A1 (https=) |
| JP (5) | JP6457501B2 (https=) |
| KR (3) | KR102292298B1 (https=) |
| CN (2) | CN105474017A (https=) |
| AU (5) | AU2014274670B2 (https=) |
| CA (1) | CA2914751C (https=) |
| CL (1) | CL2015003563A1 (https=) |
| CR (1) | CR20150638A (https=) |
| DK (1) | DK3004896T3 (https=) |
| EA (1) | EA035342B1 (https=) |
| ES (1) | ES2762608T3 (https=) |
| HR (1) | HRP20192246T1 (https=) |
| HU (1) | HUE047863T2 (https=) |
| IL (3) | IL298675B2 (https=) |
| LT (1) | LT3004896T (https=) |
| MA (1) | MA38638B1 (https=) |
| MX (1) | MX370570B (https=) |
| MY (1) | MY185990A (https=) |
| NZ (1) | NZ754328A (https=) |
| PH (1) | PH12015502687A1 (https=) |
| PL (1) | PL3004896T3 (https=) |
| PT (1) | PT3004896T (https=) |
| RS (1) | RS59677B1 (https=) |
| SG (2) | SG11201509622WA (https=) |
| SI (1) | SI3004896T1 (https=) |
| UA (1) | UA120591C2 (https=) |
| WO (1) | WO2014197859A1 (https=) |
| ZA (1) | ZA201508630B (https=) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SI3998078T1 (sl) * | 2009-08-28 | 2026-02-27 | Genzyme Corporation | Encimsko nadomestno zdravljenje z naraščajočim odmerkom za zdravljenje pomanjkanja kisle sfingomielinaze |
| ES2762608T3 (es) * | 2013-06-07 | 2020-05-25 | Genzyme Corp | Marcador para trastornos de esfingomielinasa ácida y usos del mismo |
| JP6984854B2 (ja) * | 2015-10-08 | 2021-12-22 | 国立大学法人千葉大学 | ニーマン・ピック病ｃ型を予防または治療するための医薬組成物 |
| KR20250025051A (ko) | 2017-08-24 | 2025-02-20 | 사노피 | 산성 스핑고미엘린분해효소 결핍증 환자에서의 비정상적 골병태의 치료 |
| CR20200129A (es) | 2017-10-02 | 2020-08-22 | Denali Therapeutics Inc | Proteínas de fusión que comprenden enzimas de terapia de reemplazo de enzimas |
| HUE071194T2 (hu) * | 2019-05-31 | 2025-08-28 | Genzyme Corp | Kétdimenziós LC-MS/MS rendszerek |
| WO2024026390A2 (en) * | 2022-07-28 | 2024-02-01 | Wylder Nation Foundation | Compositions and methods for diagnosing, treating, and preventing lysosomal storage diseases |
Family Cites Families (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4082781A (en) | 1976-06-04 | 1978-04-04 | The United States Of America As Represented By The Department Of Health, Education And Welfare | Synthesis of 2-alkanoylamino-4-nitrophenyl phosphorylcholine-hydroxide |
| US4039388A (en) | 1976-06-04 | 1977-08-02 | The United States Of America As Represented By The Government | Diagnostic test for Niemann-Pick disease |
| US5773278A (en) | 1991-05-03 | 1998-06-30 | Mount Sinai Medical Center | Acid sphingomyelinase gene |
| AR034413A1 (es) | 2000-08-25 | 2004-02-25 | Nestor Abel Chamoles | Metodo para determinar la actividad de las enzimas lisosomales |
| US7001994B2 (en) | 2001-01-18 | 2006-02-21 | Genzyme Corporation | Methods for introducing mannose 6-phosphate and other oligosaccharides onto glycoproteins |
| US7615224B2 (en) | 2004-12-02 | 2009-11-10 | Women's And Children's Hospital | Multiplex-bead complex for determination of lysosomal storage disorders |
| JP2006214731A (ja) * | 2005-02-01 | 2006-08-17 | Institute Of Physical & Chemical Research | スフィンゴミエリンの検出方法 |
| WO2007078806A2 (en) | 2005-12-15 | 2007-07-12 | The Research Foundation Of State University Of New York | Enzymatic methods for measuring plasma and tissue sphingomylelin and phosphatidylcholine |
| AR059089A1 (es) | 2006-01-20 | 2008-03-12 | Genzyme Corp | Administracion intraventricular de una enzima para enfermedades de almacenamiento lisosomal |
| US8026099B2 (en) | 2007-07-26 | 2011-09-27 | Washington University | Lipid profile as a biomarker for early detection of neurological disorders |
| US8497122B2 (en) | 2008-04-11 | 2013-07-30 | Washington University | Biomarkers for Niemann-pick C disease and related disorders |
| SI3998078T1 (sl) * | 2009-08-28 | 2026-02-27 | Genzyme Corporation | Encimsko nadomestno zdravljenje z naraščajočim odmerkom za zdravljenje pomanjkanja kisle sfingomielinaze |
| JP2013002933A (ja) | 2011-06-16 | 2013-01-07 | Hitachi Plant Technologies Ltd | ３次元測位システム |
| BR112014009223B1 (pt) * | 2011-11-15 | 2021-04-06 | Centogene Gmbh | Métodos para o diagnóstico da doença de niemann-pick, método para determinação do curso da doença de niemann-pick, método para determinação da eficácia de pelo menos um tratamento, uso de análise espectrométrica de massa e kit |
| JP6660291B2 (ja) * | 2013-05-14 | 2020-03-11 | セントジーン アーゲー | ニーマン・ピック病の診断のための方法 |
| ES2762608T3 (es) | 2013-06-07 | 2020-05-25 | Genzyme Corp | Marcador para trastornos de esfingomielinasa ácida y usos del mismo |
-
2014
- 2014-06-06 ES ES14735056T patent/ES2762608T3/es active Active
- 2014-06-06 EP EP19191053.8A patent/EP3584580A1/en active Pending
- 2014-06-06 LT LTEP14735056.5T patent/LT3004896T/lt unknown
- 2014-06-06 CN CN201480043918.2A patent/CN105474017A/zh active Pending
- 2014-06-06 JP JP2016518053A patent/JP6457501B2/ja active Active
- 2014-06-06 AU AU2014274670A patent/AU2014274670B2/en active Active
- 2014-06-06 IL IL298675A patent/IL298675B2/en unknown
- 2014-06-06 SG SG11201509622WA patent/SG11201509622WA/en unknown
- 2014-06-06 IL IL284102A patent/IL284102B2/en unknown
- 2014-06-06 PT PT147350565T patent/PT3004896T/pt unknown
- 2014-06-06 EP EP14735056.5A patent/EP3004896B1/en active Active
- 2014-06-06 UA UAA201600158A patent/UA120591C2/uk unknown
- 2014-06-06 RS RS20191627A patent/RS59677B1/sr unknown
- 2014-06-06 MX MX2015016844A patent/MX370570B/es active IP Right Grant
- 2014-06-06 HU HUE14735056A patent/HUE047863T2/hu unknown
- 2014-06-06 SI SI201431434T patent/SI3004896T1/sl unknown
- 2014-06-06 PL PL14735056T patent/PL3004896T3/pl unknown
- 2014-06-06 US US14/895,472 patent/US10022428B2/en active Active
- 2014-06-06 DK DK14735056.5T patent/DK3004896T3/da active
- 2014-06-06 MY MYPI2015704368A patent/MY185990A/en unknown
- 2014-06-06 SG SG10201709925SA patent/SG10201709925SA/en unknown
- 2014-06-06 KR KR1020217007269A patent/KR102292298B1/ko active Active
- 2014-06-06 CN CN202210555370.6A patent/CN115128287A/zh active Pending
- 2014-06-06 WO PCT/US2014/041405 patent/WO2014197859A1/en not_active Ceased
- 2014-06-06 KR KR1020217025969A patent/KR102434244B1/ko active Active
- 2014-06-06 EA EA201592265A patent/EA035342B1/ru not_active IP Right Cessation
- 2014-06-06 MA MA38638A patent/MA38638B1/fr unknown
- 2014-06-06 NZ NZ754328A patent/NZ754328A/en unknown
- 2014-06-06 HR HRP20192246TT patent/HRP20192246T1/hr unknown
- 2014-06-06 KR KR1020167000011A patent/KR102228367B1/ko active Active
- 2014-06-06 CA CA2914751A patent/CA2914751C/en active Active
-
2015
- 2015-11-23 ZA ZA2015/08630A patent/ZA201508630B/en unknown
- 2015-12-01 PH PH12015502687A patent/PH12015502687A1/en unknown
- 2015-12-04 CL CL2015003563A patent/CL2015003563A1/es unknown
- 2015-12-04 CR CR20150638A patent/CR20150638A/es unknown
- 2015-12-06 IL IL242964A patent/IL242964B/en unknown
-
2018
- 2018-02-09 AU AU2018200977A patent/AU2018200977B2/en active Active
- 2018-06-08 US US16/003,598 patent/US10888607B2/en active Active
- 2018-12-19 JP JP2018236856A patent/JP6835806B2/ja active Active
-
2020
- 2020-10-22 AU AU2020257114A patent/AU2020257114B2/en active Active
- 2020-12-11 US US17/119,035 patent/US11998592B2/en active Active
-
2021
- 2021-02-03 JP JP2021015390A patent/JP7414750B2/ja active Active
-
2023
- 2023-02-23 AU AU2023201062A patent/AU2023201062B2/en active Active
- 2023-12-27 JP JP2023220385A patent/JP7830414B2/ja active Active
-
2024
- 2024-04-29 US US18/649,453 patent/US12589138B2/en active Active
-
2025
- 2025-08-25 AU AU2025220876A patent/AU2025220876A1/en active Pending
- 2025-12-10 JP JP2025244095A patent/JP2026041958A/ja active Pending
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2016526050A5 (https=) | ||
| Garg et al. | Subacute sclerosing panencephalitis | |
| Ortega et al. | Role of HIV in amyloid metabolism | |
| Macrez et al. | Mechanisms of glutamate toxicity in multiple sclerosis: biomarker and therapeutic opportunities | |
| Vlisides et al. | Neurotoxicity of general anesthetics: an update | |
| Silva et al. | Muscle dysfunction in the long coronavirus disease 2019 syndrome: Pathogenesis and clinical approach | |
| Dursun et al. | The interleukin 1 alpha, interleukin 1 beta, interleukin 6 and alpha-2-macroglobulin serum levels in patients with early or late onset Alzheimer's disease, mild cognitive impairment or Parkinson's disease | |
| Mathis et al. | Management and therapeutic perspectives in amyotrophic lateral sclerosis | |
| McClafferty et al. | Approach to critical illness myopathy and polyneuropathy in the older SARS-CoV-2 patients | |
| Smith et al. | Effects of a novel sodium channel blocker, GSK2339345, in patients with refractory chronic cough | |
| Wood et al. | Mannitol challenge for assessment of airway responsiveness, airway inflammation and inflammatory phenotype in asthma | |
| JP2026041958A5 (https=) | ||
| JP2016516074A5 (https=) | ||
| CN108289930A (zh) | 用于治疗神经退行性和神经炎性病症的方法和组合物 | |
| Gromova et al. | Direct and indirect neurological signs of COVID-19 | |
| NZ754328A (en) | Marker for acid sphingomyelinase disorders and uses thereof | |
| Patil et al. | Nintedanib as an antifibrotic in post COVID lung fibrosis: Are we really overestimating | |
| Gao et al. | Effectiveness and tolerability of adjunctive perampanel in the treatment of pediatric patients with uncontrolled epilepsy: a retrospective, single-center, real-world study | |
| JP2017519008A5 (https=) | ||
| KR101619238B1 (ko) | 체내 단백질 응집체의 용해를 이용한 단백질의 비정상적인 응집 또는 미스폴딩과 관련된 질환 또는 질병을 진단하는 혈액진단키트 | |
| Shah et al. | Chronic kidney disease–associated pruritus: what is known and its application in children | |
| Levin et al. | Efficacy of akatinol memantine in moderate cognitive impairments | |
| WO2024011094A1 (en) | Regimen for treating amyotrophic lateral sclerosis having onset 24 months prior to treatment | |
| Taniguchi et al. | Chest pain relieved with a bronchodilator or other asthma drugs | |
| US20250099544A1 (en) | Treatment of Type 1 Diabetes and Other Conditions Using the Gut Microbiome |