JP2016526016A - がんを治療する方法 - Google Patents

がんを治療する方法 Download PDF

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Publication number
JP2016526016A
JP2016526016A JP2016512011A JP2016512011A JP2016526016A JP 2016526016 A JP2016526016 A JP 2016526016A JP 2016512011 A JP2016512011 A JP 2016512011A JP 2016512011 A JP2016512011 A JP 2016512011A JP 2016526016 A JP2016526016 A JP 2016526016A
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JP
Japan
Prior art keywords
fgfr1
cancer
ecd
fgfr1 ecd
overexpression
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JP2016512011A
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English (en)
Japanese (ja)
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JP2016526016A5 (https=
Inventor
ジュリー ハンブルトン，
ジュリー ハンブルトン，
モーリーン アール． ブリーム，
モーリーン アール． ブリーム，
モーリス ピー． デヤング，
モーリス ピー． デヤング，
ジェラルディーン フェロン−ブレイディ，
ジェラルディーン フェロン−ブレイディ，
ラケシュ クマール，
ラケシュ クマール，
ローン オッテセン，
ローン オッテセン，
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GlaxoSmithKline Intellectual Property No 2 Ltd
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GlaxoSmithKline Intellectual Property No 2 Ltd
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Publication of JP2016526016A publication Critical patent/JP2016526016A/ja
Publication of JP2016526016A5 publication Critical patent/JP2016526016A5/ja
Pending legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/177—Receptors; Cell surface antigens; Cell surface determinants
    • A61K38/179—Receptors; Cell surface antigens; Cell surface determinants for growth factors; for growth regulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Cell Biology (AREA)
  • Zoology (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Dermatology (AREA)
  • Peptides Or Proteins (AREA)
  • Toxicology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
JP2016512011A 2013-05-01 2014-04-30 がんを治療する方法 Pending JP2016526016A (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201361818220P 2013-05-01 2013-05-01
US61/818,220 2013-05-01
US201361831029P 2013-06-04 2013-06-04
US61/831,029 2013-06-04
PCT/US2014/036140 WO2014179448A2 (en) 2013-05-01 2014-04-30 Methods of treating cancer

Publications (2)

Publication Number Publication Date
JP2016526016A true JP2016526016A (ja) 2016-09-01
JP2016526016A5 JP2016526016A5 (https=) 2017-06-15

Family

ID=50928263

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2016512011A Pending JP2016526016A (ja) 2013-05-01 2014-04-30 がんを治療する方法

Country Status (13)

Country Link
US (2) US20160067307A1 (https=)
EP (1) EP2991669A2 (https=)
JP (1) JP2016526016A (https=)
KR (1) KR20160003141A (https=)
CN (1) CN105188732A (https=)
AU (1) AU2014259956A1 (https=)
BR (1) BR112015027607A8 (https=)
CA (1) CA2908391A1 (https=)
HK (1) HK1213817A1 (https=)
MX (1) MX2015015115A (https=)
RU (1) RU2015150233A (https=)
SG (1) SG11201508878WA (https=)
WO (1) WO2014179448A2 (https=)

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EP1910542B1 (en) 2005-07-22 2009-12-02 Five Prime Therapeutics, Inc. Compositions and methods of treating disease with fgfr fusion proteins
US8481038B2 (en) 2010-11-15 2013-07-09 Five Prime Therapeutics, Inc. Treatment of cancer with elevated dosages of soluble FGFR1 fusion proteins
JP2015505818A (ja) 2011-11-14 2015-02-26 ファイブ プライム セラピューティックス インコーポレイテッド 癌を治療する方法
PH12021552742A1 (en) 2013-08-01 2022-05-23 Five Prime Therapeutics Inc Afucosylated anti-fgfr2iiib antibodies
BR112018001438A2 (en) * 2015-07-24 2018-12-04 Debiopharm International S.A. gffr expression and susceptibility to a gffr inhibitor
US20170145103A1 (en) * 2015-11-23 2017-05-25 Five Prime Therapeutics, Inc. Predicting response to cancer treatment with fgfr2 inhibitors
PL238516B1 (pl) 2016-06-13 2021-08-30 Univ Wroclawski Sposób otrzymywania modyfikowanego polipeptydu
SG11201906249PA (en) * 2017-02-06 2019-08-27 Rainier Therapeutics Inc Methods, compositions, and kits for treatment of cancer
WO2018195273A1 (en) * 2017-04-19 2018-10-25 The Corporation Of Mercer University Sam-1 protein, composition and methods of use
SG10202112636SA (en) 2017-05-16 2021-12-30 Five Prime Therapeutics Inc Anti-fgfr2 antibodies in combination with chemotherapy agents in cancer treatment
EP3915576A1 (en) * 2020-05-28 2021-12-01 Fundació Privada Institut d'Investigació Oncològica de Vall-Hebron Chimeric antigen receptors specific for p95her2 and uses thereof

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2008525493A (ja) * 2004-12-22 2008-07-17 オキシジーン， インコーポレイテッド 腫瘍増殖および転移を調節する方法
JP2009514879A (ja) * 2005-11-04 2009-04-09 メルク エンド カムパニー インコーポレーテッド Ｓａｈａ、カルボプラチン及びパクリタキセルを用いて癌を治療する方法及びその他の併用療法
WO2012068032A1 (en) * 2010-11-15 2012-05-24 Five Prime Therapeutics, Inc. Fgfr1 extracellular domain combination therapies
WO2013074492A1 (en) * 2011-11-14 2013-05-23 Five Prime Therapeutics, Inc. Methods of treating cancer

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US4318980A (en) 1978-04-10 1982-03-09 Miles Laboratories, Inc. Heterogenous specific binding assay employing a cycling reactant as label
EP0154316B1 (en) 1984-03-06 1989-09-13 Takeda Chemical Industries, Ltd. Chemically modified lymphokine and production thereof
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WO2001075166A2 (en) 2000-03-31 2001-10-11 Genentech, Inc. Compositions and methods for detecting and quantifying gene expression
KR20130056201A (ko) 2000-05-19 2013-05-29 제넨테크, 인크. ＥｒｂＢ 길항제에 의한 암 치료요법에 대한 효과적인 반응의 가능성을 개선시키기 위한 유전자 검출 분석
US6900292B2 (en) 2001-08-17 2005-05-31 Lee-Hwei K. Sun Fc fusion proteins of human erythropoietin with increased biological activities
JP4810427B2 (ja) 2003-05-22 2011-11-09 アボット・ラボラトリーズ インダゾール、ベンズイソオキサゾールおよびベンズイソチアゾールキナーゼ阻害剤
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EP1910542B1 (en) * 2005-07-22 2009-12-02 Five Prime Therapeutics, Inc. Compositions and methods of treating disease with fgfr fusion proteins
ES2342646B1 (es) 2008-06-02 2011-04-26 Institut De Recerca Hospital Universitari Vall Hebron Metodo de diagnostico de canceres que expresan el receptor her-2 o sus variantes truncadas.
US8481038B2 (en) * 2010-11-15 2013-07-09 Five Prime Therapeutics, Inc. Treatment of cancer with elevated dosages of soluble FGFR1 fusion proteins
US8951972B2 (en) * 2010-12-09 2015-02-10 Five Prime Therapeutics, Inc. FGFR1 extracellular domain combination therapies for lung cancer

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2008525493A (ja) * 2004-12-22 2008-07-17 オキシジーン， インコーポレイテッド 腫瘍増殖および転移を調節する方法
JP2009514879A (ja) * 2005-11-04 2009-04-09 メルク エンド カムパニー インコーポレーテッド Ｓａｈａ、カルボプラチン及びパクリタキセルを用いて癌を治療する方法及びその他の併用療法
WO2012068032A1 (en) * 2010-11-15 2012-05-24 Five Prime Therapeutics, Inc. Fgfr1 extracellular domain combination therapies
WO2013074492A1 (en) * 2011-11-14 2013-05-23 Five Prime Therapeutics, Inc. Methods of treating cancer

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
HARDING, THOMAS C. ET AL.: "Blockade of Nonhormonal Fibroblast Growth Factors by FP-1039 Inhibits Growth of Multiple Types of Ca", SCIENCE TRANSLATIONAL MEDICINE, vol. 5, no. 178, JPN7018000009, March 2013 (2013-03-01), pages 178 - 39, ISSN: 0003717134 *
PROCEEDINGS:AACR 103RD ANNUAL MEETING 2012, CANCER RESEARCH, vol. 72(8 Supplement), JPN6018051141, April 2012 (2012-04-01), pages 1876, ISSN: 0004083900 *
中島誠ほか: "非小細胞肺がんに対する３ｗｅｅｋｓ−カルボプラチン／パクリタキセル併用療法におけるアプレピタントの有", 医療薬学, vol. 39, no. 5, JPN6018000227, May 2013 (2013-05-01), pages 294 - 303, ISSN: 0004083899 *

Also Published As

Publication number Publication date
SG11201508878WA (en) 2015-11-27
WO2014179448A3 (en) 2014-12-24
KR20160003141A (ko) 2016-01-08
AU2014259956A1 (en) 2015-11-12
WO2014179448A2 (en) 2014-11-06
US20160067307A1 (en) 2016-03-10
RU2015150233A (ru) 2017-06-02
EP2991669A2 (en) 2016-03-09
US20180280470A1 (en) 2018-10-04
BR112015027607A8 (pt) 2018-01-23
BR112015027607A2 (pt) 2017-12-05
CN105188732A (zh) 2015-12-23
CA2908391A1 (en) 2014-11-06
HK1213817A1 (zh) 2016-07-15
MX2015015115A (es) 2016-06-07

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