JP2016524914A5 - - Google Patents

Download PDF

Info

Publication number
JP2016524914A5
JP2016524914A5 JP2016527005A JP2016527005A JP2016524914A5 JP 2016524914 A5 JP2016524914 A5 JP 2016524914A5 JP 2016527005 A JP2016527005 A JP 2016527005A JP 2016527005 A JP2016527005 A JP 2016527005A JP 2016524914 A5 JP2016524914 A5 JP 2016524914A5
Authority
JP
Japan
Prior art keywords
hpv
cells
specific
cell population
fragments
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2016527005A
Other languages
English (en)
Japanese (ja)
Other versions
JP2016524914A (ja
JP6616295B2 (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2014/046478 external-priority patent/WO2015009604A1/en
Publication of JP2016524914A publication Critical patent/JP2016524914A/ja
Publication of JP2016524914A5 publication Critical patent/JP2016524914A5/ja
Priority to JP2019202239A priority Critical patent/JP7315435B2/ja
Application granted granted Critical
Publication of JP6616295B2 publication Critical patent/JP6616295B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

JP2016527005A 2013-07-15 2014-07-14 抗ヒトパピローマウイルス抗原t細胞の調製方法 Active JP6616295B2 (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2019202239A JP7315435B2 (ja) 2013-07-15 2019-11-07 抗ヒトパピローマウイルス抗原t細胞の調製方法

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201361846161P 2013-07-15 2013-07-15
US61/846,161 2013-07-15
PCT/US2014/046478 WO2015009604A1 (en) 2013-07-15 2014-07-14 Methods of preparing anti-human papillomavirus antigen t cells

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2019202239A Division JP7315435B2 (ja) 2013-07-15 2019-11-07 抗ヒトパピローマウイルス抗原t細胞の調製方法

Publications (3)

Publication Number Publication Date
JP2016524914A JP2016524914A (ja) 2016-08-22
JP2016524914A5 true JP2016524914A5 (cg-RX-API-DMAC7.html) 2017-08-31
JP6616295B2 JP6616295B2 (ja) 2019-12-04

Family

ID=51257632

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2016527005A Active JP6616295B2 (ja) 2013-07-15 2014-07-14 抗ヒトパピローマウイルス抗原t細胞の調製方法
JP2019202239A Active JP7315435B2 (ja) 2013-07-15 2019-11-07 抗ヒトパピローマウイルス抗原t細胞の調製方法

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2019202239A Active JP7315435B2 (ja) 2013-07-15 2019-11-07 抗ヒトパピローマウイルス抗原t細胞の調製方法

Country Status (9)

Country Link
US (8) US20160144018A1 (cg-RX-API-DMAC7.html)
EP (3) EP3022294B1 (cg-RX-API-DMAC7.html)
JP (2) JP6616295B2 (cg-RX-API-DMAC7.html)
CN (2) CN105452448B (cg-RX-API-DMAC7.html)
AU (3) AU2014290286A1 (cg-RX-API-DMAC7.html)
CA (1) CA2918080A1 (cg-RX-API-DMAC7.html)
ES (3) ES2773548T3 (cg-RX-API-DMAC7.html)
RU (1) RU2713333C2 (cg-RX-API-DMAC7.html)
WO (1) WO2015009604A1 (cg-RX-API-DMAC7.html)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10828353B2 (en) 2015-01-31 2020-11-10 The Trustees Of The University Of Pennsylvania Compositions and methods for T cell delivery of therapeutic molecules
WO2017049237A1 (en) * 2015-09-18 2017-03-23 The General Hospital Corporation Dba Massachusetts General Hospital Personalized approach to dosage of anti-fugetactic agent for treatment of cancer
EP3368051A4 (en) * 2015-10-30 2019-06-26 Children's National Medical Center GENERATION OF HPV ANTIGEN-SPECIFIC T CELLS FROM A NAIVEN T CELL POPULATION
US11834675B2 (en) * 2015-12-30 2023-12-05 Celgene Corporation T lymphocyte production methods and t lymphocytes produced thereby
AU2017338827B2 (en) 2016-10-03 2023-08-31 Juno Therapeutics, Inc. HPV-specific binding molecules
IL266209B2 (en) 2016-10-26 2025-02-01 Iovance Biotherapeutics Inc Re-stimulation of cryopreserved infiltrating lymphocytes
TWI788307B (zh) 2016-10-31 2023-01-01 美商艾歐凡斯生物治療公司 用於擴增腫瘤浸潤性淋巴細胞之工程化人造抗原呈現細胞
GB201700621D0 (en) 2017-01-13 2017-03-01 Guest Ryan Dominic Method,device and kit for the aseptic isolation,enrichment and stabilsation of cells from mammalian solid tissue
KR20190124214A (ko) * 2017-01-20 2019-11-04 아타라 바이오테라퓨틱스 인크. 자가 t 세포를 사용하여 다발성 경화증을 치료하는 방법
JOP20190224A1 (ar) 2017-03-29 2019-09-26 Iovance Biotherapeutics Inc عمليات من أجل إنتاج الخلايا اللمفاوية المرتشحة للأورام واستخداماتها في العلاج المناعي
US11254913B1 (en) 2017-03-29 2022-02-22 Iovance Biotherapeutics, Inc. Processes for production of tumor infiltrating lymphocytes and uses of same in immunotherapy
EP3635097A1 (en) 2017-06-05 2020-04-15 Iovance Biotherapeutics, Inc. Methods of using tumor infiltrating lymphocytes in double-refractory melanoma
US11952408B2 (en) 2017-10-03 2024-04-09 Juno Therapeutics, Inc. HPV-specific binding molecules
JP2021509586A (ja) 2018-01-08 2021-04-01 アイオバンス バイオセラピューティクス,インコーポレイテッド 腫瘍抗原特異的t細胞について濃縮されたtil製品を生成するためのプロセス
US11713446B2 (en) 2018-01-08 2023-08-01 Iovance Biotherapeutics, Inc. Processes for generating TIL products enriched for tumor antigen-specific T-cells
CN112585276A (zh) 2018-04-05 2021-03-30 朱诺治疗学股份有限公司 产生表达重组受体的细胞的方法和相关组合物
US20210015869A1 (en) 2018-04-05 2021-01-21 Juno Therapeutics, Inc. T cells expressing a recombinant receptor, related polynucleotides and methods
RU2020135968A (ru) 2018-04-05 2022-05-06 Джуно Терапьютикс, Инк. T-клеточные рецепторы и модифицированные клетки, экспрессирующие
WO2019196088A1 (en) * 2018-04-13 2019-10-17 Syz Cell Therapy Co. Methods of obtaining tumor-specific t cell receptors
WO2019210131A1 (en) 2018-04-27 2019-10-31 Iovance Biotherapeutics, Inc. Closed process for expansion and gene editing of tumor infiltrating lymphocytes and uses of same in immunotherapy
US12473532B2 (en) 2018-05-10 2025-11-18 Iovance Biotherapeutics, Inc. Processes for production of tumor infiltrating lymphocytes and uses of same in immunotherapy
WO2020033927A2 (en) 2018-08-09 2020-02-13 Juno Therapeutics, Inc. Processes for generating engineered cells and compositions thereof
JP7504891B2 (ja) 2018-09-11 2024-06-24 ジュノー セラピューティクス インコーポレイテッド 操作された細胞組成物のマススペクトロメトリー分析のための方法
JP2022506586A (ja) 2018-11-05 2022-01-17 アイオバンス バイオセラピューティクス,インコーポレイテッド 腫瘍浸潤リンパ球の産生のためのプロセスおよび免疫療法におけるその使用
GB201821207D0 (en) * 2018-12-24 2019-02-06 Tcer Ab Immunotherapy therapy
KR20220016475A (ko) 2019-05-01 2022-02-09 주노 쎄러퓨티크스 인코퍼레이티드 변형된 tgfbr2 유전자 좌에서 재조합 수용체를 발현하는 세포, 관련 폴리뉴클레오티드 및 방법
CN115244173A (zh) 2019-12-20 2022-10-25 英研生物(英国)有限公司 用于分离肿瘤浸润淋巴细胞的装置及方法及其用途
WO2021260186A1 (en) 2020-06-26 2021-12-30 Juno Therapeutics Gmbh Engineered t cells conditionally expressing a recombinant receptor, related polynucleotides and methods
WO2023196884A1 (en) 2022-04-06 2023-10-12 Juno Therapeutics, Inc. Detection assay for human papillomavirus (hpv) type 16 (hpv-16)
EP4507704A1 (en) 2022-04-15 2025-02-19 Iovance Biotherapeutics, Inc. Til expansion processes using specific cytokine combinations and/or akti treatment

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK1545204T3 (en) 2002-09-06 2016-11-14 The Government Of The Us Secretary Dept Of Health And Human Services Immunotherapy with in vitro selected antigen-specific lymphocytes following non-myeloablative lymphodepletive chemotherapy
CN1609196A (zh) * 2003-10-17 2005-04-27 上海普泛生物科技有限公司 用于发现肿瘤特异性抗原和肿瘤特异性抗原决定簇的高产率t淋巴细胞克隆技术
AU2009214980B2 (en) * 2008-02-11 2013-10-31 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Methods of obtaining antigen-specific T cell populations
US8383099B2 (en) * 2009-08-28 2013-02-26 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Adoptive cell therapy with young T cells
US20120244133A1 (en) 2011-03-22 2012-09-27 The United States of America, as represented by the Secretary, Department of Health and Methods of growing tumor infiltrating lymphocytes in gas-permeable containers
CN102816734A (zh) * 2012-05-09 2012-12-12 阮润生 一种肿瘤抗原特异性t细胞的获取方法

Similar Documents

Publication Publication Date Title
JP2016524914A5 (cg-RX-API-DMAC7.html)
RU2016103614A (ru) Способы получения т-клеток против антигена папилломавируса человека
Welters et al. Induction of tumor-specific CD4+ and CD8+ T-cell immunity in cervical cancer patients by a human papillomavirus type 16 E6 and E7 long peptides vaccine
Tran et al. Minimally cultured tumor-infiltrating lymphocytes display optimal characteristics for adoptive cell therapy
EP4289944A3 (en) Method for preparing genetically-modified t cells which express chimeric antigen receptor
JP2016509840A5 (cg-RX-API-DMAC7.html)
JP2012521215A5 (cg-RX-API-DMAC7.html)
MY180750A (en) Expansion of lymphocytes with a cytokine composition for active cellular immunotherapy
IL273516B2 (en) Methods of isolating t cells having antigenic specificity for a p53 cancer-specific mutation
JP2014087372A5 (cg-RX-API-DMAC7.html)
CN111902533A (zh) 产生自然杀伤细胞的方法
Ge et al. Potential biomarkers: Identifying powerful tumor specific T cells in adoptive cellular therapy
Chen et al. Blocking IL-10 signalling at the time of immunization renders the tumour more accessible to T cell infiltration in mice
WO2019070435A8 (en) Methods for selectively expanding cells expressing a tcr with a murine constant region
TWI458485B (zh) 毒殺型樹突細胞群組用於製備藥物的用途及包含其之醫藥組合物
Klein et al. Restricted expression of EBV encoded proteins in in vitro infected CLL cells
Galluzzi et al. Rejuvenated T cells attack old tumors
CN120796184A (zh) 一种用于扩增多能干细胞来源的nk细胞的非细胞刺激剂
HK40038785A (en) Methods of preparing anti-human papillomavirus antigen t cells
Torisu-Itakura et al. High IFNγ and perforin and low GM-CSF and sCD40L production correlate with CD8 TIL growth in breast cancer
Mohs et al. Blockage of CCL5/RANTES modifies immune infiltration and the inflammatory milieu during chronic liver disease: 65
HK40025869B (en) Methods of preparing anti-human papillomavirus antigen t cells
Cho et al. CT7 (MAGE-C1)-Specific Cellular Immune Responses in the Bone Marrow Microenvironment of Multiple Myeloma Patients.
Magg et al. 349: Ethylenecarbodiimide (ECDI) Coupled Allogeneic Antigen Presenting Cells Induce Human CD4+ Regulatory T Cells
Rangelova et al. GENERATION OF TUMOR-INFILTRATING LYMPHOCYTES FROM PANCREATIC CANCER FOR CELLULAR THERAPY: HP015P