JP2016524611A - がんを治療する方法 - Google Patents

がんを治療する方法 Download PDF

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JP2016524611A
JP2016524611A JP2016515080A JP2016515080A JP2016524611A JP 2016524611 A JP2016524611 A JP 2016524611A JP 2016515080 A JP2016515080 A JP 2016515080A JP 2016515080 A JP2016515080 A JP 2016515080A JP 2016524611 A JP2016524611 A JP 2016524611A
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cancer
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vegf
fgfr1
fgf2
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JP2016524611A5 (enExample
Inventor
デーヴィッド ベロヴィン,
デーヴィッド ベロヴィン,
ケヴィン ベイカー,
ケヴィン ベイカー,
トーマス ブレナン,
トーマス ブレナン,
エランダシー ニルマリニ パンディーテ,
エランダシー ニルマリニ パンディーテ,
ビジョイエッシュ ムケルジー,
ビジョイエッシュ ムケルジー,
モーリス ピー. デヤング,
モーリス ピー. デヤング,
ラケシュ クマール,
ラケシュ クマール,
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GlaxoSmithKline Intellectual Property No 2 Ltd
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GlaxoSmithKline Intellectual Property No 2 Ltd
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Publication of JP2016524611A5 publication Critical patent/JP2016524611A5/ja
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    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/177—Receptors; Cell surface antigens; Cell surface determinants
    • A61K38/179—Receptors; Cell surface antigens; Cell surface determinants for growth factors; for growth regulators
    • A—HUMAN NECESSITIES
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    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/337—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having four-membered rings, e.g. taxol
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    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
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    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
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    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
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    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
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    • G01N33/575—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/5758—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumours, cancers or neoplasias, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides or metabolites
    • G01N33/57595—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumours, cancers or neoplasias, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides or metabolites involving intracellular compounds
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    • A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
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    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
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    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
    • A—HUMAN NECESSITIES
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    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
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    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/106—Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism
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    • G01N2333/475—Assays involving growth factors
    • G01N2333/49—Platelet-derived growth factor [PDGF]
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JP2016515080A 2013-05-23 2014-05-22 がんを治療する方法 Pending JP2016524611A (ja)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US201361826975P 2013-05-23 2013-05-23
US61/826,975 2013-05-23
US201461936471P 2014-02-06 2014-02-06
US61/936,471 2014-02-06
US201461974279P 2014-04-02 2014-04-02
US61/974,279 2014-04-02
PCT/US2014/039129 WO2014190147A2 (en) 2013-05-23 2014-05-22 Methods of treating cancer

Related Child Applications (1)

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JP2018169261A Division JP2019023193A (ja) 2013-05-23 2018-09-11 がんを治療する方法

Publications (2)

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JP2016524611A true JP2016524611A (ja) 2016-08-18
JP2016524611A5 JP2016524611A5 (enExample) 2017-07-13

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JP2016515080A Pending JP2016524611A (ja) 2013-05-23 2014-05-22 がんを治療する方法
JP2018169261A Pending JP2019023193A (ja) 2013-05-23 2018-09-11 がんを治療する方法

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US (1) US9775881B2 (enExample)
EP (2) EP2999799A4 (enExample)
JP (2) JP2016524611A (enExample)
KR (1) KR20160013092A (enExample)
CN (1) CN105307669A (enExample)
AU (1) AU2014268519A1 (enExample)
BR (1) BR112015029145A2 (enExample)
CA (1) CA2909689A1 (enExample)
HK (1) HK1219513A1 (enExample)
MX (1) MX2015015426A (enExample)
RU (1) RU2015154985A (enExample)
SG (2) SG10201703977UA (enExample)
WO (1) WO2014190147A2 (enExample)
ZA (1) ZA201507762B (enExample)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2019023193A (ja) * 2013-05-23 2019-02-14 ファイヴ プライム セラピューティクス インク がんを治療する方法
JP2021518532A (ja) * 2018-03-16 2021-08-02 ザ ボード オブ トラスティーズ オブ ザ レランド スタンフォード ジュニア ユニバーシティー がんにおける治療薬に対する応答の分析

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2016090546A1 (en) * 2014-12-09 2016-06-16 Wentao Zhang Nbp158 and uses thereof
GB201609402D0 (en) * 2016-05-27 2016-07-13 Cancer Res Inst Royal Materials and methods for treating cancer
WO2024005423A1 (ko) * 2022-06-29 2024-01-04 고려대학교 산학협력단 인간 FCγRS 결합력이 제거된 당화 FC 변이체들
WO2025221718A1 (en) * 2024-04-15 2025-10-23 Arizona Board Of Regents On Behalf Of Arizona State University Repurposing fda approved therapeutics

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JP2010510801A (ja) * 2006-11-28 2010-04-08 サントリオン 生物学的活性が向上した修飾可溶性FGF受容体Fc融合物
WO2012159550A1 (zh) * 2011-05-20 2012-11-29 烟台荣昌生物工程有限公司 FGFR-Fc融合蛋白及其用途

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