JP2016521858A - 表面多孔性材料を含むクロマトグラフィーカラムおよび分離デバイス、および超臨界流体クロマトグラフィーおよび他のクロマトグラフィーのためのこれらの使用 - Google Patents

表面多孔性材料を含むクロマトグラフィーカラムおよび分離デバイス、および超臨界流体クロマトグラフィーおよび他のクロマトグラフィーのためのこれらの使用 Download PDF

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JP2016521858A
JP2016521858A JP2016519596A JP2016519596A JP2016521858A JP 2016521858 A JP2016521858 A JP 2016521858A JP 2016519596 A JP2016519596 A JP 2016519596A JP 2016519596 A JP2016519596 A JP 2016519596A JP 2016521858 A JP2016521858 A JP 2016521858A
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porous
group
core
separation device
butyl
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JP2016521858A5 (enExample
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ウィンダム，ケビン・ダニエル
フェアチャイルド，ジェイコブ・ネイサン
イラネタ，パメラ・シー
シャイナー，スティーブン・ジェームズ
ブルースミーシュ，ダリル・ダブリュ
ウォルシュ，ダニエル・ピー
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ウオーターズ・テクノロジーズ・コーポレイシヨン
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    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08—Selective adsorption, e.g. chromatography
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08—Selective adsorption, e.g. chromatography
    • B01D15/26—Selective adsorption, e.g. chromatography characterised by the separation mechanism
    • B01D15/30—Partition chromatography
    • B01D15/305—Hydrophilic interaction chromatography [HILIC]
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08—Selective adsorption, e.g. chromatography
    • B01D15/26—Selective adsorption, e.g. chromatography characterised by the separation mechanism
    • B01D15/32—Bonded phase chromatography
    • B01D15/322—Normal bonded phase
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08—Selective adsorption, e.g. chromatography
    • B01D15/26—Selective adsorption, e.g. chromatography characterised by the separation mechanism
    • B01D15/40—Selective adsorption, e.g. chromatography characterised by the separation mechanism using supercritical fluid as mobile phase or eluent
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/28—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof characterised by their form or physical properties
    • B01J20/28002—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof characterised by their form or physical properties characterised by their physical properties
    • B01J20/28004—Sorbent size or size distribution, e.g. particle size
    • B—PERFORMING OPERATIONS; TRANSPORTING
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    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/28—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof characterised by their form or physical properties
    • B01J20/28014—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof characterised by their form or physical properties characterised by their form
    • B01J20/28016—Particle form
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    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/28—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof characterised by their form or physical properties
    • B01J20/28054—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof characterised by their form or physical properties characterised by their surface properties or porosity
    • B01J20/28057—Surface area, e.g. B.E.T specific surface area
    • B—PERFORMING OPERATIONS; TRANSPORTING
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    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
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    • B01J20/28057—Surface area, e.g. B.E.T specific surface area
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    • B01J20/28057—Surface area, e.g. B.E.T specific surface area
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    • B01J20/28069—Pore volume, e.g. total pore volume, mesopore volume, micropore volume
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    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
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    • B01J20/28069—Pore volume, e.g. total pore volume, mesopore volume, micropore volume
    • B01J20/28071—Pore volume, e.g. total pore volume, mesopore volume, micropore volume being less than 0.5 ml/g
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    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
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    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/28—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof characterised by their form or physical properties
    • B01J20/28054—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof characterised by their form or physical properties characterised by their surface properties or porosity
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    • B01J20/281—Sorbents specially adapted for preparative, analytical or investigative chromatography
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    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/281—Sorbents specially adapted for preparative, analytical or investigative chromatography
    • B01J20/286—Phases chemically bonded to a substrate, e.g. to silica or to polymers
    • B—PERFORMING OPERATIONS; TRANSPORTING
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    • B01J20/32—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating
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    • C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
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    • C07F7/08—Compounds having one or more C—Si linkages
    • C07F7/18—Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
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  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Nanotechnology (AREA)
  • Inorganic Chemistry (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
  • Treatment Of Liquids With Adsorbents In General (AREA)
JP2016519596A 2013-06-11 2014-06-10 表面多孔性材料を含むクロマトグラフィーカラムおよび分離デバイス、および超臨界流体クロマトグラフィーおよび他のクロマトグラフィーのためのこれらの使用 Pending JP2016521858A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201361833699P 2013-06-11 2013-06-11
US61/833,699 2013-06-11
PCT/US2014/041765 WO2014201033A1 (en) 2013-06-11 2014-06-10 Chromatographic columns and separation devices comprising a superficially porous material; and use thereof for supercritical fluid chromatography and other chromatography

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JP2016521858A true JP2016521858A (ja) 2016-07-25
JP2016521858A5 JP2016521858A5 (enExample) 2017-07-27

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US (2) US11577179B2 (enExample)
EP (2) EP3007792A4 (enExample)
JP (1) JP2016521858A (enExample)
CN (2) CN105555383B (enExample)
WO (1) WO2014201033A1 (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR102532719B1 (ko) * 2021-12-16 2023-05-16 한국표준과학연구원 액체크로마토그래피 컬럼 충전제

Families Citing this family (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2437882A4 (en) 2009-06-01 2016-11-23 Waters Technologies Corp HYBRID MATERIAL FOR CHROMATOGRAPHY SEPARATIONS
US11439977B2 (en) 2009-06-01 2022-09-13 Waters Technologies Corporation Hybrid material for chromatographic separations comprising a superficially porous core and a surrounding material
EP3834927B1 (en) 2010-07-26 2026-03-25 Waters Technologies Corporation Method for preparing a superficially porous material
US12623205B2 (en) 2010-07-26 2026-05-12 Waters Technologies Corporation Superficially porous materials comprising a substantially nonporous hybrid core having narrow particle size distribution
US10453675B2 (en) 2013-09-20 2019-10-22 Versum Materials Us, Llc Organoaminosilane precursors and methods for depositing films comprising same
EP4063849B1 (en) * 2015-03-24 2024-01-31 Daicel Corporation Stationary phase for supercritical fluid chromatography
WO2017019845A1 (en) * 2015-07-29 2017-02-02 Imerys Filtration Minerals, Inc. Chill-proofing composite filter air and related methods
JP6810039B2 (ja) * 2015-07-31 2021-01-06 株式会社ダイセル 超臨界流体クロマトグラフィー用の固定相
US11511213B2 (en) 2015-08-13 2022-11-29 Waters Technologies Corporation Nickel-cobalt alloy material devices and components
CN121869327A (zh) * 2016-03-06 2026-04-17 沃特世科技公司 用于色谱分离的具有受控孔隙度的多孔材料；其制备方法；以及其用途
JP6813247B2 (ja) * 2016-03-23 2021-01-13 株式会社ダイセル クロマトグラフィー用の固定相
WO2017223140A1 (en) * 2016-06-21 2017-12-28 Purdue Research Foundation Uniformly dense stationary phase for chromatography
WO2018163086A1 (en) 2017-03-08 2018-09-13 Waters Technologies Corporation Polar pesticide determination using chromatography
DE102017009236A1 (de) * 2017-10-04 2019-04-04 Dr. Albin Maisch High Performance LC GmbH Oberflächenporöse Trägermaterialien sowie das Verfahren zu deren Herstellung
US11325104B2 (en) * 2017-12-07 2022-05-10 Emp Biotech Gmbh System and method of applied radial technology chromatography
CN108976561B (zh) * 2018-08-03 2021-04-02 阜南佳利工艺品有限公司 一种低气味仿藤条的制备方法
EP3614414A1 (en) * 2018-08-20 2020-02-26 FEI Company Method of examining a sample using a charged particle microscope
WO2020045648A1 (ja) * 2018-08-30 2020-03-05 株式会社ダイセル クロマトグラフィー用の固定相
CN109692501B (zh) * 2018-12-29 2021-02-09 武汉谱立科技有限公司 一种色谱柱及其制备方法和应用
US11964874B2 (en) * 2020-06-09 2024-04-23 Agilent Technologies, Inc. Etched non-porous particles and method of producing thereof
EP4210853B1 (en) * 2020-09-11 2026-07-01 W. L. Gore & Associates, Inc. Affinity chromatography devices containing a fibrinated polymer membrane and collectors containing them
CN116209517B (zh) * 2020-09-16 2026-06-16 沃特世科技公司 具有羟基封端的peg键合和甲氧基封端的peg表面改性的基于二氧化硅的颗粒
CN112451996B (zh) * 2020-11-10 2021-09-24 浙江大学 一种多柱连续流层析捕获蛋白的优化方法
EP4267270A4 (en) * 2020-12-24 2025-07-30 Ligar Lp METHOD, SYSTEM AND/OR APPARATUS FOR THE USE OF LIQUID OR FLUID CARBON DIOXIDE IN THE EXTRACTION AND/OR SOLUBILIZATION OF A SOURCE MATERIAL AND BONDING AND/OR ELUTION WITH A MOLECULARLY IMPRINTED POLYMER
CN112903837B (zh) * 2021-01-14 2022-11-04 中国工程物理研究院材料研究所 一种氢同位素气体分析用金属多孔层开管柱及其制备方法
US20230047460A1 (en) * 2021-07-30 2023-02-16 Agilent Technologies, Inc. Methods of making media of substantially monodisperse populations of polyarylketone or polyarylthioetherketone particles, and containers comprising them
US12629656B2 (en) * 2021-08-26 2026-05-19 Waters Technologies Corporation Superficially porous organic polymer particles
US20240082820A1 (en) * 2022-08-26 2024-03-14 Waters Technologies Corporation Core-shell particles having a non-porous core and a porous shell
CN119744197A (zh) * 2022-08-26 2025-04-01 沃特世科技公司 具有无孔有机-无机杂化材料的复合颗粒
WO2024042372A1 (en) * 2022-08-26 2024-02-29 Waters Technologies Corporation Bonded hybrid polymer non-porous particles and their use for bioseparations
CN116422297B (zh) * 2023-04-24 2024-04-30 中国电建集团昆明勘测设计研究院有限公司 一种改性石墨烯材料的制备方法及应用
US12616931B2 (en) * 2023-09-08 2026-05-05 Spritius Technologies, PBC High performance gas adsorbing material
CN121606628B (zh) * 2026-02-02 2026-06-12 浙江中医药大学 一种半枝莲总黄酮的提取分离方法

Citations (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0084979A2 (en) * 1982-01-26 1983-08-03 Richard Stocks Limited Wheel coupling apparatus
US4415631A (en) * 1980-06-27 1983-11-15 Akzo Porous inorganic support material coated with an organic stationary phase, for use in chromatography, and process for its preparation
US20060207923A1 (en) * 2004-02-12 2006-09-21 Li Guang Q Polar-modified bonded phase materials for chromatographic separations
US20070090052A1 (en) * 2005-10-20 2007-04-26 Broske Alan D Chromatographic stationary phase
US20070189944A1 (en) * 2006-02-13 2007-08-16 Advanced Materials Technology, Inc. Porous microparticles with solid cores
JP2010533124A (ja) * 2007-07-13 2010-10-21 ユニバーシティ・カレッジ・コークーナショナル・ユニバーシティ・オブ・アイルランド，コーク 微粒子合成方法
WO2012018598A1 (en) * 2010-07-26 2012-02-09 Waters Technologies Corporation Superficially porous materials comprising a substantially nonporous core having narrow particle size distribution; process for the preparation thereof; and use thereof for chromatographic separations
US20120055860A1 (en) * 2009-06-01 2012-03-08 Waters Technologies Corporation Hybrid inorganic/organic materials having novel surface modification; process for the preparation of inorganic/organic hybrid materials; and use of said particles for chromatographic separations
JP2012509974A (ja) * 2008-11-26 2012-04-26 ユニバーシティ・カレッジ・コークーナショナル・ユニバーシティ・オブ・アイルランド，コーク シリカ微粒子を製造する方法
WO2013173494A1 (en) * 2012-05-15 2013-11-21 Waters Technologies Corporation Chromatographic materials

Family Cites Families (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2357184A1 (de) 1973-11-16 1975-05-22 Merck Patent Gmbh Verfahren zur herstellung von organisch modifizierten siliciumdioxiden
JP2504005B2 (ja) * 1986-11-17 1996-06-05 東ソー株式会社 充填剤およびその製法
US5374755A (en) 1992-07-17 1994-12-20 Millipore Corporation Liquid chromatography stationary phases with reduced silanol interactions
US5576453A (en) 1994-07-18 1996-11-19 Es Industries Stable, sterically-protected, bonded phase silicas prepared from bifunctional silanes
US6686035B2 (en) 1999-02-05 2004-02-03 Waters Investments Limited Porous inorganic/organic hybrid particles for chromatographic separations and process for their preparation
US6528167B2 (en) 2001-01-31 2003-03-04 Waters Investments Limited Porous hybrid particles with organic groups removed from the surface
DE10393207B4 (de) 2002-09-10 2022-04-07 Waters Technologies Corp. (N.D.Ges.D. Staates Delaware) Chromatographiesäule, Verfahren zu deren Herstellung sowie Verfahren zum Durchführen einer chromatographischen Trennung
WO2004041398A2 (en) 2002-10-30 2004-05-21 Waters Investments Limited Porous inorganic/organic hybrid materials and preparation thereof
US7074491B2 (en) 2003-11-04 2006-07-11 Dionex Corporation Polar silanes for binding to substrates and use of the bound substrates
US8658277B2 (en) 2004-07-30 2014-02-25 Waters Technologies Corporation Porous inorganic/organic hybrid materials with ordered domains for chromatographic separations and processes for their preparation
US7402243B2 (en) 2004-09-10 2008-07-22 Dionex Corporation Organosilanes and substrate bonded with same
ES2579756T3 (es) 2004-10-01 2016-08-16 Phenomenex, Inc. Medio cromatográfico con pH estable que utiliza plantilla multicapa orgánica / inorgánica injertada
CN1262476C (zh) * 2004-11-03 2006-07-05 武汉理工大学 单分散二氧化硅微孔微球及其制备方法
JP4936208B2 (ja) 2005-06-20 2012-05-23 株式会社豊田中央研究所 コアシェル型球状シリカ系メソ多孔体及びコアシェル型球状シリカ系メソ多孔体の製造方法
US9308520B2 (en) 2005-12-16 2016-04-12 Akzo Nobel N.V. Silica based material
EP2008971A4 (en) 2006-04-20 2010-08-04 Asahi Glass Co Ltd CORE SHELL SILICON DIOXIDE AND MANUFACTURING METHOD THEREFOR
US9120083B2 (en) 2007-02-21 2015-09-01 Waters Technologies Corporation Porous inorganic/organic hybrid particles having high organic content and enhanced pore geometry for chromatographic separations
WO2008121453A2 (en) 2007-02-22 2008-10-09 Waters Investments Limited Device, apparatus and method for performing separations
US7534352B2 (en) 2007-05-01 2009-05-19 Agilent Technologies, Inc. Reversed endcapping and bonding of chromatographic stationary phases using hydrosilanes
US20090218276A1 (en) 2008-02-29 2009-09-03 Brigham Young University Functionalized diamond particles and methods for preparing the same
US9248383B2 (en) 2008-04-08 2016-02-02 Waters Technologies Corporation Composite materials containing nanoparticles and their use in chromatography
US8277883B2 (en) 2008-06-13 2012-10-02 Agilent Technologies, Inc. Porous silica microspheres having organosilane modified surfaces
US8685283B2 (en) 2008-08-29 2014-04-01 Agilent Technologies, Inc. Superficially porous metal oxide particles, methods for making them, and separation devices using them
US9284456B2 (en) 2008-08-29 2016-03-15 Agilent Technologies, Inc. Superficially porous metal oxide particles, methods for making them, and separation devices using them
US20100061367A1 (en) 2008-09-11 2010-03-11 Pradeep Sindhu Methods and apparatus related to lossless operation within a data center
US7846337B2 (en) 2009-02-17 2010-12-07 Agilent Technologies, Inc. Superficially porous particles and methods of making and using same
US8219758B2 (en) 2009-07-10 2012-07-10 Apple Inc. Block-based non-transparent cache
EP2462188A4 (en) * 2009-08-04 2016-11-23 Waters Technologies Corp HIGH-QUALITY CHROMATOGRAPHIC MATERIALS WITH A IONIZABLE MODIFIER
WO2012110995A1 (en) 2011-02-16 2012-08-23 Glantreo Limited Silica core-shell microparticles

Patent Citations (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4415631A (en) * 1980-06-27 1983-11-15 Akzo Porous inorganic support material coated with an organic stationary phase, for use in chromatography, and process for its preparation
EP0084979A2 (en) * 1982-01-26 1983-08-03 Richard Stocks Limited Wheel coupling apparatus
US20060207923A1 (en) * 2004-02-12 2006-09-21 Li Guang Q Polar-modified bonded phase materials for chromatographic separations
US20070090052A1 (en) * 2005-10-20 2007-04-26 Broske Alan D Chromatographic stationary phase
US20070189944A1 (en) * 2006-02-13 2007-08-16 Advanced Materials Technology, Inc. Porous microparticles with solid cores
JP2010533124A (ja) * 2007-07-13 2010-10-21 ユニバーシティ・カレッジ・コークーナショナル・ユニバーシティ・オブ・アイルランド，コーク 微粒子合成方法
JP2012509974A (ja) * 2008-11-26 2012-04-26 ユニバーシティ・カレッジ・コークーナショナル・ユニバーシティ・オブ・アイルランド，コーク シリカ微粒子を製造する方法
US20120055860A1 (en) * 2009-06-01 2012-03-08 Waters Technologies Corporation Hybrid inorganic/organic materials having novel surface modification; process for the preparation of inorganic/organic hybrid materials; and use of said particles for chromatographic separations
WO2012018598A1 (en) * 2010-07-26 2012-02-09 Waters Technologies Corporation Superficially porous materials comprising a substantially nonporous core having narrow particle size distribution; process for the preparation thereof; and use thereof for chromatographic separations
WO2012018596A2 (en) * 2010-07-26 2012-02-09 Waters Technologies Corporation Superficially porous materials comprising a substantially nonporous hybrid core having narrow particle size distribution; process for the preparation thereof; and use thereof for chromatographic separations
US20130112605A1 (en) * 2010-07-26 2013-05-09 Waters Technologies Corporation Superficially porous materials comprising a substantially nonporous core having narrow particle size distribution; process for the preparation thereof; and use thereof for chromatographic separations
WO2013173494A1 (en) * 2012-05-15 2013-11-21 Waters Technologies Corporation Chromatographic materials

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR102532719B1 (ko) * 2021-12-16 2023-05-16 한국표준과학연구원 액체크로마토그래피 컬럼 충전제

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