JP2016521266A5 - - Google Patents
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- Publication number
- JP2016521266A5 JP2016521266A5 JP2016507617A JP2016507617A JP2016521266A5 JP 2016521266 A5 JP2016521266 A5 JP 2016521266A5 JP 2016507617 A JP2016507617 A JP 2016507617A JP 2016507617 A JP2016507617 A JP 2016507617A JP 2016521266 A5 JP2016521266 A5 JP 2016521266A5
- Authority
- JP
- Japan
- Prior art keywords
- combination
- ibrutinib
- lymphoma
- relapsed
- refractory
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000002177 L01XE27 - Ibrutinib Substances 0.000 claims 22
- XYFPWWZEPKGCCK-GOSISDBHSA-N ibrutinib Chemical compound C1=2C(N)=NC=NC=2N([C@H]2CN(CCC2)C(=O)C=C)N=C1C(C=C1)=CC=C1OC1=CC=CC=C1 XYFPWWZEPKGCCK-GOSISDBHSA-N 0.000 claims 22
- 229960001507 ibrutinib Drugs 0.000 claims 22
- 210000003719 b-lymphocyte Anatomy 0.000 claims 10
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims 9
- 230000002062 proliferating effect Effects 0.000 claims 9
- 208000010839 B-cell chronic lymphocytic leukemia Diseases 0.000 claims 8
- 208000031671 Large B-Cell Diffuse Lymphoma Diseases 0.000 claims 8
- 206010012818 diffuse large B-cell lymphoma Diseases 0.000 claims 8
- LQBVNQSMGBZMKD-UHFFFAOYSA-N venetoclax Chemical compound C=1C=C(Cl)C=CC=1C=1CC(C)(C)CCC=1CN(CC1)CCN1C(C=C1OC=2C=C3C=CNC3=NC=2)=CC=C1C(=O)NS(=O)(=O)C(C=C1[N+]([O-])=O)=CC=C1NCC1CCOCC1 LQBVNQSMGBZMKD-UHFFFAOYSA-N 0.000 claims 7
- 229960001183 venetoclax Drugs 0.000 claims 7
- 208000031422 Lymphocytic Chronic B-Cell Leukemia Diseases 0.000 claims 5
- 239000002775 capsule Substances 0.000 claims 4
- 208000025205 Mantle-Cell Lymphoma Diseases 0.000 claims 3
- 239000002552 dosage form Substances 0.000 claims 2
- 201000003444 follicular lymphoma Diseases 0.000 claims 2
- 201000007924 marginal zone B-cell lymphoma Diseases 0.000 claims 2
- 208000021937 marginal zone lymphoma Diseases 0.000 claims 2
- 208000024893 Acute lymphoblastic leukemia Diseases 0.000 claims 1
- 208000014697 Acute lymphocytic leukaemia Diseases 0.000 claims 1
- 208000036170 B-Cell Marginal Zone Lymphoma Diseases 0.000 claims 1
- 208000003950 B-cell lymphoma Diseases 0.000 claims 1
- 208000011691 Burkitt lymphomas Diseases 0.000 claims 1
- 201000004085 CLL/SLL Diseases 0.000 claims 1
- 206010025323 Lymphomas Diseases 0.000 claims 1
- 208000034578 Multiple myelomas Diseases 0.000 claims 1
- 201000003793 Myelodysplastic syndrome Diseases 0.000 claims 1
- 206010035226 Plasma cell myeloma Diseases 0.000 claims 1
- 208000006664 Precursor Cell Lymphoblastic Leukemia-Lymphoma Diseases 0.000 claims 1
- 208000033559 Waldenström macroglobulinemia Diseases 0.000 claims 1
- 230000001154 acute effect Effects 0.000 claims 1
- 210000004027 cell Anatomy 0.000 claims 1
- 230000001684 chronic effect Effects 0.000 claims 1
- 208000032852 chronic lymphocytic leukemia Diseases 0.000 claims 1
- 208000023738 chronic lymphocytic leukemia/small lymphocytic lymphoma Diseases 0.000 claims 1
- 210000001280 germinal center Anatomy 0.000 claims 1
- 208000021173 high grade B-cell lymphoma Diseases 0.000 claims 1
- 208000032839 leukemia Diseases 0.000 claims 1
- 230000000306 recurrent effect Effects 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361809810P | 2013-04-08 | 2013-04-08 | |
| US61/809,810 | 2013-04-08 | ||
| PCT/US2014/033378 WO2014168975A1 (en) | 2013-04-08 | 2014-04-08 | Ibrutinib combination therapy |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019147994A Division JP6871978B2 (ja) | 2013-04-08 | 2019-08-09 | イブルチニブ併用療法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2016521266A JP2016521266A (ja) | 2016-07-21 |
| JP2016521266A5 true JP2016521266A5 (enExample) | 2017-05-25 |
| JP6575952B2 JP6575952B2 (ja) | 2019-09-18 |
Family
ID=51689963
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016507617A Active JP6575952B2 (ja) | 2013-04-08 | 2014-04-08 | イブルチニブ併用療法 |
| JP2019147994A Active JP6871978B2 (ja) | 2013-04-08 | 2019-08-09 | イブルチニブ併用療法 |
| JP2021069171A Pending JP2021119150A (ja) | 2013-04-08 | 2021-04-15 | イブルチニブ併用療法 |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019147994A Active JP6871978B2 (ja) | 2013-04-08 | 2019-08-09 | イブルチニブ併用療法 |
| JP2021069171A Pending JP2021119150A (ja) | 2013-04-08 | 2021-04-15 | イブルチニブ併用療法 |
Country Status (14)
| Country | Link |
|---|---|
| US (2) | US20160287592A1 (enExample) |
| EP (1) | EP2983670A4 (enExample) |
| JP (3) | JP6575952B2 (enExample) |
| KR (1) | KR20150141971A (enExample) |
| CN (2) | CN111317821A (enExample) |
| AU (3) | AU2014251028A1 (enExample) |
| BR (1) | BR112015025711A8 (enExample) |
| CA (1) | CA2908375A1 (enExample) |
| EA (1) | EA201591656A1 (enExample) |
| HK (1) | HK1215374A1 (enExample) |
| IL (2) | IL241710B (enExample) |
| MX (2) | MX369503B (enExample) |
| PH (2) | PH12015502337A1 (enExample) |
| WO (1) | WO2014168975A1 (enExample) |
Families Citing this family (76)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BRPI0906473A8 (pt) | 2008-01-04 | 2016-02-10 | Intellikine Inc | Certas entidades químicas, composições e métodos |
| US8193182B2 (en) | 2008-01-04 | 2012-06-05 | Intellikine, Inc. | Substituted isoquinolin-1(2H)-ones, and methods of use thereof |
| CN102159214A (zh) | 2008-07-16 | 2011-08-17 | 药品循环公司 | 用于实体肿瘤的治疗的布鲁顿酪氨酸激酶的抑制剂 |
| MX380504B (es) | 2010-06-03 | 2025-03-12 | Pharmacyclics Llc | El uso de inhibidores de la tirosina quinasa de bruton (btk). |
| EP3238722B1 (en) | 2011-01-10 | 2019-03-13 | Infinity Pharmaceuticals, Inc. | Solid forms of isoquinolinones |
| KR20140048968A (ko) | 2011-07-13 | 2014-04-24 | 파마시클릭스, 인코포레이티드 | 브루톤형 티로신 키나제의 억제제 |
| CN103889987B (zh) | 2011-07-19 | 2016-09-14 | 默沙东有限责任公司 | 作为btk抑制剂的选择的咪唑并吡嗪类 |
| EP2548877A1 (en) | 2011-07-19 | 2013-01-23 | MSD Oss B.V. | 4-(5-Membered fused pyridinyl)benzamides as BTK-inhibitors |
| DK2734205T3 (en) | 2011-07-21 | 2018-06-14 | Tolero Pharmaceuticals Inc | Heterocyclic Protein Kinase Inhibitors |
| MA37711A1 (fr) | 2012-06-04 | 2017-05-31 | Pharmacyclics Inc | Formes cristallines d'un inhibiteur de tyrosine kinase de bruton |
| US8828998B2 (en) | 2012-06-25 | 2014-09-09 | Infinity Pharmaceuticals, Inc. | Treatment of lupus, fibrotic conditions, and inflammatory myopathies and other disorders using PI3 kinase inhibitors |
| HK1206073A1 (en) | 2012-07-24 | 2015-12-31 | 药品循环有限责任公司 | Mutations associated with resistance to inhibitors of bruton's tyrosine kinase (btk) |
| RU2702908C2 (ru) | 2012-11-01 | 2019-10-14 | Инфинити Фармасьютикалз, Инк. | Лечение злокачественных опухолей с использованием модуляторов изоформ pi3-киназы |
| PT2970205T (pt) | 2013-03-14 | 2019-08-26 | Tolero Pharmaceuticals Inc | Inibidores da jak2 e da alk2 e métodos para a sua utilização |
| JP6430483B2 (ja) | 2013-03-15 | 2018-11-28 | ジー1、セラピューティクス、インコーポレイテッドG1 Therapeutics, Inc. | 化学療法の間の正常細胞の一時的な保護 |
| CA2906157C (en) | 2013-03-15 | 2022-05-17 | G1 Therapeutics, Inc. | Highly active anti-neoplastic and anti-proliferative agents |
| JP6800750B2 (ja) * | 2013-08-02 | 2020-12-16 | ファーマサイクリックス エルエルシー | 固形腫瘍の処置方法 |
| CA2920534A1 (en) | 2013-08-12 | 2015-02-19 | Pharmacyclics Llc | Methods for the treatment of her2 amplified cancer |
| CA3103411A1 (en) * | 2013-10-25 | 2015-04-30 | Pharmacyclics Llc | Use of ibrutinib for treating and preventing chronic graft versus host disease |
| EP3076974A1 (en) | 2013-12-05 | 2016-10-12 | Acerta Pharma B.V. | Therapeutic combination of a pi3k inhibitor and a btk inhibitor |
| US9885086B2 (en) | 2014-03-20 | 2018-02-06 | Pharmacyclics Llc | Phospholipase C gamma 2 and resistance associated mutations |
| WO2015146159A1 (en) | 2014-03-25 | 2015-10-01 | Ono Pharmaceutical Co., Ltd. | Prophylactic agent and/or therapeutic agent for diffuse large b-cell lymphoma |
| US9937171B2 (en) | 2014-04-11 | 2018-04-10 | Acerta Pharma B.V. | Methods of blocking the CXCR-4/SDF-1 signaling pathway with inhibitors of bruton's tyrosine kinase |
| WO2015160975A2 (en) | 2014-04-16 | 2015-10-22 | Infinity Pharmaceuticals, Inc. | Combination therapies |
| WO2015161283A1 (en) | 2014-04-17 | 2015-10-22 | G1 Therapeutics, Inc. | Tricyclic lactams for use in hspc-sparing treatments for rb-positive abnormal cellular proliferation |
| CN105017256A (zh) | 2014-04-29 | 2015-11-04 | 浙江导明医药科技有限公司 | 多氟化合物作为布鲁顿酪氨酸激酶抑制剂 |
| WO2015193740A2 (en) * | 2014-06-17 | 2015-12-23 | Acerta Pharma B.V. | Therapeutic combinations of a btk inhibitor, a pi3k inhibitor and/or a jak-2 inhibitor |
| SMT202100674T1 (it) | 2014-08-11 | 2022-01-10 | Acerta Pharma Bv | Combinazioni terapeutiche di un inibitore di btk e un inibitore di bcl-2 |
| EP3191098A4 (en) | 2014-09-12 | 2018-04-25 | G1 Therapeutics, Inc. | Combinations and dosing regimes to treat rb-positive tumors |
| WO2016040848A1 (en) | 2014-09-12 | 2016-03-17 | G1 Therapeutics, Inc. | Treatment of rb-negative tumors using topoisomerase inhibitors in combination with cyclin dependent kinase 4/6 inhibitors |
| TW201628622A (zh) * | 2014-11-17 | 2016-08-16 | 製藥公司 | Tlr抑制劑與布魯頓氏(bruton's)酪胺酸激酶抑制劑之組合 |
| WO2016090255A1 (en) * | 2014-12-05 | 2016-06-09 | Sriram Balasubramanian | Biological markers for predicting responsiveness to ibrutinib and r-chop combination therapy and methods of using the same |
| IL315294A (en) | 2015-03-03 | 2024-10-01 | Pharmacyclics Llc | Pharmaceutical formulations of proton tyrosine kinase inhibitor |
| US9717745B2 (en) * | 2015-03-19 | 2017-08-01 | Zhejiang DTRM Biopharma Co. Ltd. | Pharmaceutical compositions and their use for treatment of cancer and autoimmune diseases |
| MA41827A (fr) * | 2015-03-27 | 2018-01-30 | Pharmacyclics Llc | Formes solvatées d'un inhibiteur de la tyrosine kinase de bruton |
| KR20170134462A (ko) | 2015-04-13 | 2017-12-06 | 다이이찌 산쿄 가부시키가이샤 | Mdm2 저해제와 btk 저해제의 병용 치료법 |
| MX391720B (es) | 2015-04-20 | 2025-03-21 | Epizyme Inc | Terapia combinada para tratar cáncer. |
| IL293821A (en) | 2015-07-02 | 2022-08-01 | Acerta Pharma Bv | Solid forms and formulations of (S)-4-(8-amino-3-(1-(but-2-aminoyl)pyrrolidine-2-yl)imidazo[5,1-yl]pyrazin-1-yl)-en- (pyridine-2-yl)benzamide |
| JP2018522028A (ja) * | 2015-07-31 | 2018-08-09 | ファーマサイクリックス エルエルシー | ブルトン型チロシンキナーゼ阻害剤の組み合わせ及びそれらの使用 |
| AU2016304172A1 (en) * | 2015-08-03 | 2018-03-15 | Gilead Sciences, Inc. | Combination therapies for treating cancers |
| EP3355871A1 (en) * | 2015-10-02 | 2018-08-08 | Gilead Sciences, Inc. | Combinations of the btk inhibitor gs-4059 with inhibitors selected from a jak, ask1, brd and/or mmp9 inhibitor to treat cancer, allergic disorders, autoimmune diseases or inflammatory diseases |
| WO2017087947A2 (en) * | 2015-11-19 | 2017-05-26 | Pharmacyclics Llc | Method of treatment of follicular lymphoma with a btk inhibitor |
| EP3474856B1 (en) | 2016-06-24 | 2022-09-14 | Infinity Pharmaceuticals, Inc. | Combination therapies |
| AU2017290362B2 (en) | 2016-07-01 | 2021-08-05 | Pharmacosmos Holding A/S | Synthesis of N-(heteroaryl)-pyrrolo[3,2-d]pyrimidin-2-amines |
| EP3484477B1 (en) | 2016-07-14 | 2023-09-13 | Mingsight Pharmaceuticals, Inc. | Treatment of cancer |
| KR101911063B1 (ko) * | 2016-07-29 | 2018-10-23 | 이화여자대학교 산학협력단 | 크로메논 유도체 및 이를 포함하는 항암용 조성물 |
| CN109789127B (zh) | 2016-07-29 | 2022-03-25 | 英克特诺治疗公司 | 吲哚啉酮化合物的用途 |
| IL317919A (en) | 2016-12-05 | 2025-02-01 | G1 Therapeutics Inc | Preservation of immune response during chemotherapy regimens |
| US11040027B2 (en) | 2017-01-17 | 2021-06-22 | Heparegenix Gmbh | Protein kinase inhibitors for promoting liver regeneration or reducing or preventing hepatocyte death |
| EP3626239B1 (en) * | 2017-05-18 | 2024-07-03 | Jiangsu Hengrui Pharmaceuticals Co., Ltd. | Ezh2 inhibitor combined with btk inhibitor for treating tumor |
| CN111565721A (zh) * | 2017-09-19 | 2020-08-21 | 西普拉有限公司 | 具有增强的生物利用度的包含依鲁替尼和生物碱的组合物 |
| TW201922256A (zh) | 2017-10-27 | 2019-06-16 | 中國大陸商浙江導明醫藥科技有限公司 | 治療淋巴樣惡性疾病之方法 |
| CN112165939A (zh) * | 2018-03-21 | 2021-01-01 | 梅制药公司 | 联合疗法 |
| BR112020020246A8 (pt) | 2018-04-05 | 2022-10-18 | Sumitomo Dainippon Pharma Oncology Inc | Inibidores de cinase axl e uso dos mesmos |
| MX2020010556A (es) | 2018-04-13 | 2021-03-02 | Sumitomo Pharma Oncology Inc | Inhibidores de cinasa de insercion proviral en linfomas murinos (pim) para el tratamiento de neoplasias mieloproliferativas y fibrosis asociadas con cancer. |
| BR112020022185A2 (pt) | 2018-05-03 | 2021-02-02 | Juno Therapeutics Inc | terapia de combinação de uma terapia de células t do receptor de antígeno quimérico (car) e um inibidor de quinase |
| KR20210038906A (ko) | 2018-07-26 | 2021-04-08 | 스미토모 다이니폰 파마 온콜로지, 인크. | 비정상적 acvr1 발현과 연관된 질환을 치료하는 방법 및 그에 사용하기 위한 acvr1 억제제 |
| CA3095699A1 (en) * | 2018-07-31 | 2020-02-06 | Ascentage Pharma (Suzhou) Co., Ltd. | Combination product of bcl-2 inhibitor and chemotherapeutic agent and use thereof in the prevention and/or treatment of diseases |
| KR102962306B1 (ko) | 2018-08-24 | 2026-05-08 | 쥐원 쎄라퓨틱스, 인크. | 1,4-디아자스피로[5.5]운데칸-3-온의 개선된 합성 |
| JP7541974B2 (ja) * | 2018-08-26 | 2024-08-29 | カーディフ・オンコロジー・インコーポレイテッド | Plk1標的のリン酸化状態及びplk1阻害剤を用いた癌の治療 |
| US20220362357A1 (en) * | 2018-08-31 | 2022-11-17 | Stichting Radboud Universitair Medisch Centrum | Synergistic Combinations of Amino Acid Depletion Agent Sensitizers (AADAS) and Amino Acid Depletion Agents (AADA), and Therapeutic Methods of Use Thereof |
| JP2022500408A (ja) * | 2018-09-12 | 2022-01-04 | デノボ バイオファーマ エルエルシー | エンザスタウリンとbtkの阻害剤との組合せおよびその使用 |
| US20200171001A1 (en) * | 2018-11-30 | 2020-06-04 | Aptose Biosciences Inc. | Combination therapy with 2,3-dihydro-isoindole-1-one compounds and methods for treating patients with various mutations |
| JP2022513666A (ja) * | 2018-11-30 | 2022-02-09 | ヤンセン バイオテツク,インコーポレーテツド | 濾胞性リンパ腫の治療方法 |
| HUE072069T2 (hu) | 2019-02-12 | 2025-10-28 | Sumitomo Pharma America Inc | 2-((1R,4R)-4-((3-(3-(trifluormetil)fenil)imidazo[1,2- b]piridazin-6-il)amino)ciklohexil)propán-2-ol sósavas sójának kristályos formája |
| US20200262925A1 (en) * | 2019-02-15 | 2020-08-20 | Janssen Biotech, Inc. | Combination Therapy For Treatment Of B-Cell Malignancies |
| WO2020186149A1 (en) * | 2019-03-13 | 2020-09-17 | The Brigham And Women's Hospital, Inc. | Targeting regulatory b cells and their regulators for cancer immunotherapy |
| EP4101468A4 (en) * | 2020-02-05 | 2024-02-28 | Carna Biosciences, Inc. | Anticancer agent composition |
| US10988479B1 (en) | 2020-06-15 | 2021-04-27 | G1 Therapeutics, Inc. | Morphic forms of trilaciclib and methods of manufacture thereof |
| GB202009764D0 (en) * | 2020-06-26 | 2020-08-12 | Cambridge Entpr Ltd | Therapeutic treatment using protein kinase c (pkc) inhibitors and cytotoxic agents |
| US20230010803A1 (en) * | 2021-06-30 | 2023-01-12 | Janssen Pharmaceutica Nv | Treatments for diffuse large b-cell lymphoma |
| WO2023285677A1 (en) * | 2021-07-16 | 2023-01-19 | Spexis Ag | Pharmaceutical combinations for treating cancer |
| US20250302954A1 (en) | 2022-05-11 | 2025-10-02 | Celgene Corporation | Methods to overcome drug resistance by re-sensitizing cancer cells to treatment with a prior therapy via treatment with a t cell therapy |
| CN115554301A (zh) * | 2022-10-24 | 2023-01-03 | 徐诺药业(南京)有限公司 | Hdac抑制剂和伊布替尼在制备预防或者治疗套细胞淋巴瘤的药物中的用途 |
| AU2023372386A1 (en) | 2022-10-31 | 2025-05-08 | Sumitomo Pharma America, Inc. | Pim1 inhibitor for treating myeloproliferative neoplasms |
| WO2025249980A1 (ko) * | 2024-05-31 | 2025-12-04 | (주)노보메디슨 | 림프종의 예방 또는 치료를 위한 포셀티닙의 병용투여 요법 |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2008001156A1 (en) * | 2006-06-26 | 2008-01-03 | Centre Regional De Lutte Contre Le Cancer - Centre Francois Baclesse | CANCER THERAPY USING BcI-XL-SPECIFIC siNA |
| EP2529621B1 (en) * | 2006-09-22 | 2016-10-05 | Pharmacyclics LLC | Inhibitors of bruton's tyrosine kinase |
| EP2126082A1 (en) * | 2007-03-02 | 2009-12-02 | MDRNA, Inc. | Nucleic acid compounds for inhibiting bcl2 gene expression and uses thereof |
| DK2134374T3 (en) * | 2007-03-14 | 2014-02-24 | Bionsil S R L In Liquidazione | BTK-INHIBITORS FOR USE IN PROCESSING chemotherapeutic agent RESISTANT TUMORS Epithelial |
| WO2009118384A1 (en) * | 2008-03-27 | 2009-10-01 | Janssen Pharmaceutica Nv | Quinazolinone derivatives as tubulin polymerization inhibitors |
| ES2546294T7 (es) * | 2009-05-26 | 2024-06-06 | Abbvie Ireland Unlimited Co | Agentes inductores de la apoptosis para el tratamiento de cáncer y enfermedades inmunitarias y autoinmunitarias |
| MX380504B (es) * | 2010-06-03 | 2025-03-12 | Pharmacyclics Llc | El uso de inhibidores de la tirosina quinasa de bruton (btk). |
| EP3919079A1 (en) * | 2012-09-07 | 2021-12-08 | Genentech, Inc. | Combination therapy of a type ii anti-cd20 antibody with a selective bcl-2 inhibitor |
-
2014
- 2014-04-08 US US14/778,536 patent/US20160287592A1/en not_active Abandoned
- 2014-04-08 CN CN201911007617.5A patent/CN111317821A/zh active Pending
- 2014-04-08 WO PCT/US2014/033378 patent/WO2014168975A1/en not_active Ceased
- 2014-04-08 EA EA201591656A patent/EA201591656A1/ru unknown
- 2014-04-08 EP EP14782886.7A patent/EP2983670A4/en not_active Withdrawn
- 2014-04-08 CN CN201480025176.0A patent/CN105263496A/zh active Pending
- 2014-04-08 BR BR112015025711A patent/BR112015025711A8/pt not_active Application Discontinuation
- 2014-04-08 JP JP2016507617A patent/JP6575952B2/ja active Active
- 2014-04-08 MX MX2015013970A patent/MX369503B/es active IP Right Grant
- 2014-04-08 HK HK16103284.1A patent/HK1215374A1/zh unknown
- 2014-04-08 KR KR1020157029969A patent/KR20150141971A/ko not_active Ceased
- 2014-04-08 AU AU2014251028A patent/AU2014251028A1/en not_active Abandoned
- 2014-04-08 CA CA2908375A patent/CA2908375A1/en not_active Abandoned
-
2015
- 2015-09-20 IL IL241710A patent/IL241710B/en active IP Right Grant
- 2015-10-02 MX MX2019013429A patent/MX2019013429A/es unknown
- 2015-10-08 PH PH12015502337A patent/PH12015502337A1/en unknown
-
2018
- 2018-11-14 IL IL263026A patent/IL263026A/en unknown
-
2019
- 2019-05-07 AU AU2019203205A patent/AU2019203205A1/en not_active Abandoned
- 2019-08-01 US US16/529,467 patent/US20200368235A1/en not_active Abandoned
- 2019-08-09 JP JP2019147994A patent/JP6871978B2/ja active Active
-
2020
- 2020-12-01 PH PH12020552065A patent/PH12020552065A1/en unknown
-
2021
- 2021-01-07 AU AU2021200066A patent/AU2021200066A1/en not_active Abandoned
- 2021-04-15 JP JP2021069171A patent/JP2021119150A/ja active Pending
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