JP2016521266A5 - - Google Patents
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- Publication number
- JP2016521266A5 JP2016521266A5 JP2016507617A JP2016507617A JP2016521266A5 JP 2016521266 A5 JP2016521266 A5 JP 2016521266A5 JP 2016507617 A JP2016507617 A JP 2016507617A JP 2016507617 A JP2016507617 A JP 2016507617A JP 2016521266 A5 JP2016521266 A5 JP 2016521266A5
- Authority
- JP
- Japan
- Prior art keywords
- combination
- ibrutinib
- lymphoma
- relapsed
- refractory
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000002177 L01XE27 - Ibrutinib Substances 0.000 claims 22
- XYFPWWZEPKGCCK-GOSISDBHSA-N ibrutinib Chemical compound C1=2C(N)=NC=NC=2N([C@H]2CN(CCC2)C(=O)C=C)N=C1C(C=C1)=CC=C1OC1=CC=CC=C1 XYFPWWZEPKGCCK-GOSISDBHSA-N 0.000 claims 22
- 229960001507 ibrutinib Drugs 0.000 claims 22
- 210000003719 b-lymphocyte Anatomy 0.000 claims 10
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims 9
- 230000002062 proliferating effect Effects 0.000 claims 9
- 208000010839 B-cell chronic lymphocytic leukemia Diseases 0.000 claims 8
- 208000031671 Large B-Cell Diffuse Lymphoma Diseases 0.000 claims 8
- 206010012818 diffuse large B-cell lymphoma Diseases 0.000 claims 8
- LQBVNQSMGBZMKD-UHFFFAOYSA-N venetoclax Chemical compound C=1C=C(Cl)C=CC=1C=1CC(C)(C)CCC=1CN(CC1)CCN1C(C=C1OC=2C=C3C=CNC3=NC=2)=CC=C1C(=O)NS(=O)(=O)C(C=C1[N+]([O-])=O)=CC=C1NCC1CCOCC1 LQBVNQSMGBZMKD-UHFFFAOYSA-N 0.000 claims 7
- 229960001183 venetoclax Drugs 0.000 claims 7
- 208000031422 Lymphocytic Chronic B-Cell Leukemia Diseases 0.000 claims 5
- 239000002775 capsule Substances 0.000 claims 4
- 208000025205 Mantle-Cell Lymphoma Diseases 0.000 claims 3
- 239000002552 dosage form Substances 0.000 claims 2
- 201000003444 follicular lymphoma Diseases 0.000 claims 2
- 201000007924 marginal zone B-cell lymphoma Diseases 0.000 claims 2
- 208000021937 marginal zone lymphoma Diseases 0.000 claims 2
- 208000024893 Acute lymphoblastic leukemia Diseases 0.000 claims 1
- 208000014697 Acute lymphocytic leukaemia Diseases 0.000 claims 1
- 208000036170 B-Cell Marginal Zone Lymphoma Diseases 0.000 claims 1
- 208000003950 B-cell lymphoma Diseases 0.000 claims 1
- 208000011691 Burkitt lymphomas Diseases 0.000 claims 1
- 201000004085 CLL/SLL Diseases 0.000 claims 1
- 206010025323 Lymphomas Diseases 0.000 claims 1
- 208000034578 Multiple myelomas Diseases 0.000 claims 1
- 201000003793 Myelodysplastic syndrome Diseases 0.000 claims 1
- 206010035226 Plasma cell myeloma Diseases 0.000 claims 1
- 208000006664 Precursor Cell Lymphoblastic Leukemia-Lymphoma Diseases 0.000 claims 1
- 208000033559 Waldenström macroglobulinemia Diseases 0.000 claims 1
- 230000001154 acute effect Effects 0.000 claims 1
- 210000004027 cell Anatomy 0.000 claims 1
- 230000001684 chronic effect Effects 0.000 claims 1
- 208000032852 chronic lymphocytic leukemia Diseases 0.000 claims 1
- 208000023738 chronic lymphocytic leukemia/small lymphocytic lymphoma Diseases 0.000 claims 1
- 210000001280 germinal center Anatomy 0.000 claims 1
- 208000021173 high grade B-cell lymphoma Diseases 0.000 claims 1
- 208000032839 leukemia Diseases 0.000 claims 1
- 230000000306 recurrent effect Effects 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361809810P | 2013-04-08 | 2013-04-08 | |
| US61/809,810 | 2013-04-08 | ||
| PCT/US2014/033378 WO2014168975A1 (en) | 2013-04-08 | 2014-04-08 | Ibrutinib combination therapy |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019147994A Division JP6871978B2 (ja) | 2013-04-08 | 2019-08-09 | イブルチニブ併用療法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2016521266A JP2016521266A (ja) | 2016-07-21 |
| JP2016521266A5 true JP2016521266A5 (enExample) | 2017-05-25 |
| JP6575952B2 JP6575952B2 (ja) | 2019-09-18 |
Family
ID=51689963
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016507617A Active JP6575952B2 (ja) | 2013-04-08 | 2014-04-08 | イブルチニブ併用療法 |
| JP2019147994A Active JP6871978B2 (ja) | 2013-04-08 | 2019-08-09 | イブルチニブ併用療法 |
| JP2021069171A Pending JP2021119150A (ja) | 2013-04-08 | 2021-04-15 | イブルチニブ併用療法 |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019147994A Active JP6871978B2 (ja) | 2013-04-08 | 2019-08-09 | イブルチニブ併用療法 |
| JP2021069171A Pending JP2021119150A (ja) | 2013-04-08 | 2021-04-15 | イブルチニブ併用療法 |
Country Status (14)
| Country | Link |
|---|---|
| US (2) | US20160287592A1 (enExample) |
| EP (1) | EP2983670A4 (enExample) |
| JP (3) | JP6575952B2 (enExample) |
| KR (1) | KR20150141971A (enExample) |
| CN (2) | CN105263496A (enExample) |
| AU (3) | AU2014251028A1 (enExample) |
| BR (1) | BR112015025711A8 (enExample) |
| CA (1) | CA2908375A1 (enExample) |
| EA (1) | EA201591656A1 (enExample) |
| HK (1) | HK1215374A1 (enExample) |
| IL (2) | IL241710B (enExample) |
| MX (2) | MX369503B (enExample) |
| PH (2) | PH12015502337A1 (enExample) |
| WO (1) | WO2014168975A1 (enExample) |
Families Citing this family (75)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
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| DK2240451T3 (da) | 2008-01-04 | 2017-11-20 | Intellikine Llc | Isoquinolinonderivater substitueret med en purin, der er anvendelig som pi3k-inhibitorer |
| AU2009270856B2 (en) | 2008-07-16 | 2013-07-25 | Pharmacyclics Llc | Inhibitors of Bruton's tyrosine kinase for the treatment of solid tumors |
| EA201890869A3 (ru) | 2010-06-03 | 2019-03-29 | Фармасайкликс, Инк. | Применение ингибиторов тирозинкиназы брутона (btk) |
| PE20180318A1 (es) | 2011-01-10 | 2018-02-09 | Infinity Pharmaceuticals Inc | Procedimiento para preparar isoquinolinonas y formas solidas de isoquinolinonas |
| AU2012283775A1 (en) | 2011-07-13 | 2014-01-23 | Pharmacyclics Llc | Inhibitors of Bruton's tyrosine kinase |
| EP2548877A1 (en) | 2011-07-19 | 2013-01-23 | MSD Oss B.V. | 4-(5-Membered fused pyridinyl)benzamides as BTK-inhibitors |
| JP5826931B2 (ja) | 2011-07-19 | 2015-12-02 | メルク・シャープ・エンド・ドーム・ベー・フェー | Ｂｔｋ阻害剤としての４−イミダゾピリダジン−１−イル−ベンズアミドおよび４−イミダゾトリアジン−１−イル−ベンズアミド |
| EP3409278B8 (en) | 2011-07-21 | 2020-11-04 | Sumitomo Dainippon Pharma Oncology, Inc. | Heterocyclic protein kinase inhibitors |
| CA3218491A1 (en) | 2012-06-04 | 2013-12-12 | Pharmacyclics Llc | Crystalline forms of a bruton's tyrosine kinase inhibitor |
| US8828998B2 (en) | 2012-06-25 | 2014-09-09 | Infinity Pharmaceuticals, Inc. | Treatment of lupus, fibrotic conditions, and inflammatory myopathies and other disorders using PI3 kinase inhibitors |
| WO2014018567A1 (en) | 2012-07-24 | 2014-01-30 | Pharmacyclics, Inc. | Mutations associated with resistance to inhibitors of bruton's tyrosine kinase (btk) |
| LT2914296T (lt) | 2012-11-01 | 2018-09-25 | Infinity Pharmaceuticals, Inc. | Vėžio gydymas, panaudojant p13 kinazės izoformos moduliatorius |
| US10202356B2 (en) | 2013-03-14 | 2019-02-12 | Tolero Pharmaceuticals, Inc. | JAK2 and ALK2 inhibitors and methods for their use |
| EP2967050A4 (en) | 2013-03-15 | 2016-09-28 | G1 Therapeutics Inc | HIGH-ACTIVE ANTINEOPLASTIC AND ANTIPROLIFERATIVE AGENTS |
| EP2968291B1 (en) | 2013-03-15 | 2025-04-16 | Pharmacosmos Holding A/S | Hspc-sparing treatments for rb-positive abnormal cellular proliferation |
| AR097204A1 (es) * | 2013-08-02 | 2016-02-24 | Pharmacyclics Inc | Métodos de tratamiento de tumores sólidos |
| EP3033079B1 (en) | 2013-08-12 | 2018-10-31 | Pharmacyclics LLC | Methods for the treatment of her2 amplified cancer |
| MX392373B (es) * | 2013-10-25 | 2025-03-24 | Pharmacyclics Llc | Uso de ibrutinib en el tratamiento de enfermedad injerto contra huesped cronica |
| US10328080B2 (en) | 2013-12-05 | 2019-06-25 | Acerta Pharma, B.V. | Therapeutic combination of PI3K inhibitor and a BTK inhibitor |
| CA2942528A1 (en) | 2014-03-20 | 2015-09-24 | Pharmacyclics Inc. | Phospholipase c gamma 2 and resistance associated mutations |
| WO2015146159A1 (en) | 2014-03-25 | 2015-10-01 | Ono Pharmaceutical Co., Ltd. | Prophylactic agent and/or therapeutic agent for diffuse large b-cell lymphoma |
| WO2015181633A2 (en) | 2014-04-11 | 2015-12-03 | Acerta Pharma B.V. | Methods of blocking the cxcr-4/sdf-1 signaling pathway with inhibitors of bruton's tyrosine kinase |
| US20150320755A1 (en) | 2014-04-16 | 2015-11-12 | Infinity Pharmaceuticals, Inc. | Combination therapies |
| US9717735B2 (en) | 2014-04-17 | 2017-08-01 | G1 Therapeutics, Inc. | Tricyclic lactams for use in HSPC-sparing treatments for RB-positive abnormal cellular proliferation |
| CN105017256A (zh) | 2014-04-29 | 2015-11-04 | 浙江导明医药科技有限公司 | 多氟化合物作为布鲁顿酪氨酸激酶抑制剂 |
| US9949971B2 (en) | 2014-06-17 | 2018-04-24 | Acerta Pharma B.V. | Therapeutic combinations of a BTK inhibitor, a PI3K inhibitor and/or a JAK-2 inhibitor |
| LT3179991T (lt) | 2014-08-11 | 2021-11-10 | Acerta Pharma B.V. | Terapiniai btk inhibitoriaus ir bcl-2 inhibitoriaus deriniai |
| WO2016040858A1 (en) * | 2014-09-12 | 2016-03-17 | G1 Therapeutics, Inc. | Combinations and dosing regimes to treat rb-positive tumors |
| WO2016040848A1 (en) | 2014-09-12 | 2016-03-17 | G1 Therapeutics, Inc. | Treatment of rb-negative tumors using topoisomerase inhibitors in combination with cyclin dependent kinase 4/6 inhibitors |
| TW201628622A (zh) * | 2014-11-17 | 2016-08-16 | 製藥公司 | Tlr抑制劑與布魯頓氏(bruton's)酪胺酸激酶抑制劑之組合 |
| WO2016090255A1 (en) * | 2014-12-05 | 2016-06-09 | Sriram Balasubramanian | Biological markers for predicting responsiveness to ibrutinib and r-chop combination therapy and methods of using the same |
| IL315294A (en) | 2015-03-03 | 2024-10-01 | Pharmacyclics Llc | Pharmaceutical formulations of bruton's tyrosine kinase inhibitor |
| US9717745B2 (en) | 2015-03-19 | 2017-08-01 | Zhejiang DTRM Biopharma Co. Ltd. | Pharmaceutical compositions and their use for treatment of cancer and autoimmune diseases |
| MA41827A (fr) * | 2015-03-27 | 2018-01-30 | Pharmacyclics Llc | Formes solvatées d'un inhibiteur de la tyrosine kinase de bruton |
| JP6823587B2 (ja) | 2015-04-13 | 2021-02-03 | 第一三共株式会社 | Ｍｄｍ２阻害剤とｂｔｋ阻害剤との併用治療法 |
| MX391720B (es) | 2015-04-20 | 2025-03-21 | Epizyme Inc | Terapia combinada para tratar cáncer. |
| HRP20211511T1 (hr) | 2015-07-02 | 2021-12-24 | Acerta Pharma B.V. | Čvrsti oblici i formulacije (s)-4-(8-amino-3-(1-(but-2-inoil)pirolidin-2-il)imidazo[1,5-a]pirazin-1-il)-n-(piridin-2-il)benzamida |
| US20170027941A1 (en) * | 2015-07-31 | 2017-02-02 | Pharmacyclics Llc | Bruton's Tyrosine Kinase Inhibitor Combinations and Uses Thereof |
| TW201717953A (zh) * | 2015-08-03 | 2017-06-01 | 基利科學股份有限公司 | 用於治療癌症之組合療法 |
| CA3000746A1 (en) * | 2015-10-02 | 2017-04-06 | Gilead Sciences, Inc. | Combinations of the btk inhibitor gs-4059 with inhibitors selected from a jak, ask1, brd and/or mmp9 inhibitor to treat cancer, allergic disorders, autoimmune diseases or inflammatory diseases |
| WO2017087947A2 (en) * | 2015-11-19 | 2017-05-26 | Pharmacyclics Llc | Method of treatment of follicular lymphoma with a btk inhibitor |
| UA125216C2 (uk) | 2016-06-24 | 2022-02-02 | Інфініті Фармасьютікалз, Інк. | Комбінована терапія |
| AU2017290362B2 (en) | 2016-07-01 | 2021-08-05 | Pharmacosmos Holding A/S | Synthesis of N-(heteroaryl)-pyrrolo[3,2-d]pyrimidin-2-amines |
| JP2019524700A (ja) | 2016-07-14 | 2019-09-05 | ミングサイト ファーマシューティカルズ，インク． | 癌の処置 |
| CN114569606B (zh) * | 2016-07-29 | 2024-04-19 | 英克特诺治疗公司 | 吲哚啉酮化合物的用途 |
| WO2018021890A1 (ko) * | 2016-07-29 | 2018-02-01 | 이화여자대학교 산학협력단 | 크로메논 유도체 및 이를 포함하는 항암용 조성물 |
| KR20240023677A (ko) | 2016-12-05 | 2024-02-22 | 쥐원 쎄라퓨틱스, 인크. | 화학요법 레지멘 동안의 면역 반응의 보존 |
| US11040027B2 (en) | 2017-01-17 | 2021-06-22 | Heparegenix Gmbh | Protein kinase inhibitors for promoting liver regeneration or reducing or preventing hepatocyte death |
| MY201580A (en) | 2017-05-18 | 2024-03-02 | Jiangsu Hengrui Medicine Co | Use of ezh2 inhibitor combined with btk inhibitor in preparing drug for treating tumor |
| WO2019058386A1 (en) * | 2017-09-19 | 2019-03-28 | Cipla Limited | COMPOSITIONS COMPRISING IBRUTINIB AND AN ALKALOID HAVING IMPROVED BIOAVAILABILITY |
| TW201922256A (zh) | 2017-10-27 | 2019-06-16 | 中國大陸商浙江導明醫藥科技有限公司 | 治療淋巴樣惡性疾病之方法 |
| SG11202009137PA (en) * | 2018-03-21 | 2020-10-29 | Mei Pharma Inc | Combination therapy |
| CA3096984A1 (en) | 2018-04-05 | 2019-10-10 | Sumitomo Dainippon Pharma Oncology, Inc. | Axl kinase inhibitors and use of the same |
| US20210113562A1 (en) | 2018-04-13 | 2021-04-22 | Sumitomo Dainippon Pharma Oncology, Inc. | Pim kinase inhibitors for treatment of myeloproliferative neoplasms and fibrosis associated with cancer |
| EP3787751A1 (en) | 2018-05-03 | 2021-03-10 | Juno Therapeutics, Inc. | Combination therapy of a chimeric antigen receptor (car) t cell therapy and a kinase inhibitor |
| MX2021000977A (es) | 2018-07-26 | 2021-04-12 | Sumitomo Pharma Oncology Inc | Metodos para tratar enfermedades asociadas con expresion anormal de receptor de activina a tipo 1 (acvr1) e inhibidores de acvr1 para uso en los mismos. |
| CA3095699A1 (en) * | 2018-07-31 | 2020-02-06 | Ascentage Pharma (Suzhou) Co., Ltd. | Combination product of bcl-2 inhibitor and chemotherapeutic agent and use thereof in the prevention and/or treatment of diseases |
| CN120817904A (zh) | 2018-08-24 | 2025-10-21 | 法码科思莫斯有限公司 | 1,4-二氮杂螺[5.5]十一烷-3-酮改进的合成 |
| US20210222228A1 (en) * | 2018-08-26 | 2021-07-22 | Cardiff Oncology, Inc. | Plk1 target phosphorylation status and treatment of cancer with plk1 inhibitors |
| WO2020043321A1 (en) * | 2018-08-31 | 2020-03-05 | Stichting Katholieke Universiteit | Synergistic combinations of amino acid depletion agent sensitizers (aadas) and amino acid depletion agents (aada), and therapeutic methods of use thereof |
| JP2022500408A (ja) * | 2018-09-12 | 2022-01-04 | デノボ バイオファーマ エルエルシー | エンザスタウリンとｂｔｋの阻害剤との組合せおよびその使用 |
| US20200171001A1 (en) * | 2018-11-30 | 2020-06-04 | Aptose Biosciences Inc. | Combination therapy with 2,3-dihydro-isoindole-1-one compounds and methods for treating patients with various mutations |
| AU2019388899A1 (en) * | 2018-11-30 | 2021-06-10 | Janssen Biotech, Inc. | Methods of treating follicular lymphoma |
| CA3127502A1 (en) | 2019-02-12 | 2020-08-20 | Sumitomo Dainippon Pharma Oncology, Inc. | Formulations comprising heterocyclic protein kinase inhibitors |
| WO2020165861A1 (en) * | 2019-02-15 | 2020-08-20 | Janssen Biotech, Inc. | Combination therapy for treatment of b-cell malignancies |
| EP3938399A4 (en) * | 2019-03-13 | 2023-04-12 | The Brigham & Women's Hospital, Inc. | TARGETING REGULATORY B LYMPHOCYTES AND THEIR REGULATORS FOR CANCER IMMUNOTHERAPY |
| US20230100235A1 (en) | 2020-02-05 | 2023-03-30 | Carna Biosciences, Inc. | Anticancer agent composition |
| US10988479B1 (en) | 2020-06-15 | 2021-04-27 | G1 Therapeutics, Inc. | Morphic forms of trilaciclib and methods of manufacture thereof |
| GB202009764D0 (en) * | 2020-06-26 | 2020-08-12 | Cambridge Entpr Ltd | Therapeutic treatment using protein kinase c (pkc) inhibitors and cytotoxic agents |
| WO2023275330A1 (en) * | 2021-06-30 | 2023-01-05 | Janssen Pharmaceutica Nv | Treatments for diffuse large b-cell lymphoma |
| WO2023285677A1 (en) * | 2021-07-16 | 2023-01-19 | Spexis Ag | Pharmaceutical combinations for treating cancer |
| WO2023220655A1 (en) | 2022-05-11 | 2023-11-16 | Celgene Corporation | Methods to overcome drug resistance by re-sensitizing cancer cells to treatment with a prior therapy via treatment with a t cell therapy |
| CN115554301A (zh) * | 2022-10-24 | 2023-01-03 | 徐诺药业(南京)有限公司 | Hdac抑制剂和伊布替尼在制备预防或者治疗套细胞淋巴瘤的药物中的用途 |
| EP4611753A1 (en) | 2022-10-31 | 2025-09-10 | Sumitomo Pharma America, Inc. | Pim1 inhibitor for treating myeloproliferative neoplasms |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2008001156A1 (en) * | 2006-06-26 | 2008-01-03 | Centre Regional De Lutte Contre Le Cancer - Centre Francois Baclesse | CANCER THERAPY USING BcI-XL-SPECIFIC siNA |
| PT2201840E (pt) * | 2006-09-22 | 2012-02-14 | Pharmacyclics Inc | Inibidores da tirosina quinase de bruton |
| WO2008109449A1 (en) * | 2007-03-02 | 2008-09-12 | Mdrna Inc. | Nucleic acid compounds for inhibiting bcl2 gene expression and uses thereof |
| WO2008110624A2 (en) * | 2007-03-14 | 2008-09-18 | Universita' Degli Studi Di Milano-Bicocca | Sirna-mediated silencing of genes for treating chemotherapeutic drug-resistant epithelial tumors |
| AU2009228945B2 (en) * | 2008-03-27 | 2013-05-02 | Janssen Pharmaceutica Nv | Quinazolinone derivatives as tubulin polymerization inhibitors |
| BR122019016429B1 (pt) * | 2009-05-26 | 2020-03-24 | Abbvie Ireland Unlimited Company | Compostos inibidores da atividade de proteínas bcl-2 antiapoptótica e composição farmacêutica compreendendo ditos compostos |
| EA201890869A3 (ru) * | 2010-06-03 | 2019-03-29 | Фармасайкликс, Инк. | Применение ингибиторов тирозинкиназы брутона (btk) |
| CN111481552A (zh) * | 2012-09-07 | 2020-08-04 | 吉宁特有限公司 | II型抗CD20抗体与选择性Bcl-2抑制剂的组合治疗 |
-
2014
- 2014-04-08 BR BR112015025711A patent/BR112015025711A8/pt not_active Application Discontinuation
- 2014-04-08 AU AU2014251028A patent/AU2014251028A1/en not_active Abandoned
- 2014-04-08 EA EA201591656A patent/EA201591656A1/ru unknown
- 2014-04-08 HK HK16103284.1A patent/HK1215374A1/zh unknown
- 2014-04-08 US US14/778,536 patent/US20160287592A1/en not_active Abandoned
- 2014-04-08 MX MX2015013970A patent/MX369503B/es active IP Right Grant
- 2014-04-08 WO PCT/US2014/033378 patent/WO2014168975A1/en not_active Ceased
- 2014-04-08 CA CA2908375A patent/CA2908375A1/en not_active Abandoned
- 2014-04-08 KR KR1020157029969A patent/KR20150141971A/ko not_active Ceased
- 2014-04-08 CN CN201480025176.0A patent/CN105263496A/zh active Pending
- 2014-04-08 CN CN201911007617.5A patent/CN111317821A/zh active Pending
- 2014-04-08 EP EP14782886.7A patent/EP2983670A4/en not_active Withdrawn
- 2014-04-08 JP JP2016507617A patent/JP6575952B2/ja active Active
-
2015
- 2015-09-20 IL IL241710A patent/IL241710B/en active IP Right Grant
- 2015-10-02 MX MX2019013429A patent/MX2019013429A/es unknown
- 2015-10-08 PH PH12015502337A patent/PH12015502337A1/en unknown
-
2018
- 2018-11-14 IL IL263026A patent/IL263026A/en unknown
-
2019
- 2019-05-07 AU AU2019203205A patent/AU2019203205A1/en not_active Abandoned
- 2019-08-01 US US16/529,467 patent/US20200368235A1/en not_active Abandoned
- 2019-08-09 JP JP2019147994A patent/JP6871978B2/ja active Active
-
2020
- 2020-12-01 PH PH12020552065A patent/PH12020552065A1/en unknown
-
2021
- 2021-01-07 AU AU2021200066A patent/AU2021200066A1/en not_active Abandoned
- 2021-04-15 JP JP2021069171A patent/JP2021119150A/ja active Pending
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