JP2016518811A5 - - Google Patents
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- Publication number
- JP2016518811A5 JP2016518811A5 JP2015561932A JP2015561932A JP2016518811A5 JP 2016518811 A5 JP2016518811 A5 JP 2016518811A5 JP 2015561932 A JP2015561932 A JP 2015561932A JP 2015561932 A JP2015561932 A JP 2015561932A JP 2016518811 A5 JP2016518811 A5 JP 2016518811A5
- Authority
- JP
- Japan
- Prior art keywords
- allele
- fetuses
- ratio
- cutoff value
- determining
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 108700028369 Alleles Proteins 0.000 claims 90
- 210000003754 fetus Anatomy 0.000 claims 83
- 102000054766 genetic haplotypes Human genes 0.000 claims 71
- 238000000034 method Methods 0.000 claims 56
- 230000008774 maternal effect Effects 0.000 claims 50
- 239000012472 biological sample Substances 0.000 claims 23
- 230000008775 paternal effect Effects 0.000 claims 18
- 239000012634 fragment Substances 0.000 claims 14
- 210000000349 chromosome Anatomy 0.000 claims 10
- 230000001605 fetal effect Effects 0.000 claims 6
- 210000004027 cell Anatomy 0.000 claims 5
- 208000022602 disease susceptibility Diseases 0.000 claims 4
- 108090000623 proteins and genes Proteins 0.000 claims 3
- 208000025341 autosomal recessive disease Diseases 0.000 claims 2
- 239000000969 carrier Substances 0.000 claims 2
- 238000004590 computer program Methods 0.000 claims 2
- 230000002068 genetic effect Effects 0.000 claims 2
- 208000025261 autosomal dominant disease Diseases 0.000 claims 1
- 201000010099 disease Diseases 0.000 claims 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims 1
- 238000005259 measurement Methods 0.000 claims 1
- 230000035945 sensitivity Effects 0.000 claims 1
- 238000012163 sequencing technique Methods 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361789992P | 2013-03-15 | 2013-03-15 | |
| US61/789,992 | 2013-03-15 | ||
| PCT/CN2014/073506 WO2014139477A1 (en) | 2013-03-15 | 2014-03-17 | Determining fetal genomes for multiple fetus pregnancies |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2016518811A JP2016518811A (ja) | 2016-06-30 |
| JP2016518811A5 true JP2016518811A5 (https=) | 2017-04-13 |
Family
ID=51535879
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015561932A Pending JP2016518811A (ja) | 2013-03-15 | 2014-03-17 | 多胎妊娠における胎児ゲノムの決定 |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US10106836B2 (https=) |
| EP (2) | EP2971126B1 (https=) |
| JP (1) | JP2016518811A (https=) |
| KR (1) | KR20150132216A (https=) |
| CN (1) | CN105121660B (https=) |
| AU (1) | AU2014231358A1 (https=) |
| CA (1) | CA2901773A1 (https=) |
| EA (1) | EA201500939A1 (https=) |
| MX (1) | MX363345B (https=) |
| TW (1) | TWI637058B (https=) |
| WO (1) | WO2014139477A1 (https=) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3783110B1 (en) | 2009-11-05 | 2022-11-23 | The Chinese University Of Hong Kong | Fetal genomic analysis from a maternal biological sample |
| CA2827873C (en) | 2011-02-24 | 2022-08-16 | The Chinese University Of Hong Kong | Molecular testing of multiple pregnancies |
| CN105121660B (zh) | 2013-03-15 | 2018-09-28 | 香港中文大学 | 确定多胎妊娠的胎儿基因组 |
| US10689706B2 (en) | 2015-07-20 | 2020-06-23 | The Chinese University Of Hong Kong | Methylation pattern analysis of haplotypes in tissues in a DNA mixture |
Family Cites Families (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9704444D0 (en) | 1997-03-04 | 1997-04-23 | Isis Innovation | Non-invasive prenatal diagnosis |
| US6927028B2 (en) | 2001-08-31 | 2005-08-09 | Chinese University Of Hong Kong | Non-invasive methods for detecting non-host DNA in a host using epigenetic differences between the host and non-host DNA |
| US7727720B2 (en) | 2002-05-08 | 2010-06-01 | Ravgen, Inc. | Methods for detection of genetic disorders |
| EP1599608A4 (en) | 2003-03-05 | 2007-07-18 | Genetic Technologies Ltd | Identification of fetal DNA and fetal cell marker in maternal plasma or serum |
| ATE435301T1 (de) | 2003-10-16 | 2009-07-15 | Sequenom Inc | Nicht invasiver nachweis fötaler genetischer merkmale |
| US7645576B2 (en) | 2005-03-18 | 2010-01-12 | The Chinese University Of Hong Kong | Method for the detection of chromosomal aneuploidies |
| US20070122823A1 (en) | 2005-09-01 | 2007-05-31 | Bianchi Diana W | Amniotic fluid cell-free fetal DNA fragment size pattern for prenatal diagnosis |
| GB0523276D0 (en) | 2005-11-15 | 2005-12-21 | London Bridge Fertility | Chromosomal analysis by molecular karyotyping |
| EP3591068A1 (en) | 2006-02-02 | 2020-01-08 | The Board of Trustees of the Leland Stanford Junior University | Non-invasive fetal genetic screening by digital analysis |
| EP2351858B1 (en) | 2006-02-28 | 2014-12-31 | University of Louisville Research Foundation | Detecting fetal chromosomal abnormalities using tandem single nucleotide polymorphisms |
| EP2029779A4 (en) | 2006-06-14 | 2010-01-20 | Living Microsystems Inc | HIGHLY PARALLEL SNP GENOTYPING UTILIZATION FOR FETAL DIAGNOSIS |
| PL2557520T3 (pl) | 2007-07-23 | 2021-10-11 | The Chinese University Of Hong Kong | Określanie zaburzenia równowagi sekwencji kwasu nukleinowego |
| US12180549B2 (en) | 2007-07-23 | 2024-12-31 | The Chinese University Of Hong Kong | Diagnosing fetal chromosomal aneuploidy using genomic sequencing |
| EP2321642B1 (en) | 2008-08-04 | 2017-01-11 | Natera, Inc. | Methods for allele calling and ploidy calling |
| KR101781147B1 (ko) | 2008-12-22 | 2017-10-10 | 셀루라 인코포레이티드 | 대립유전자, 게놈 및 전사체 검출을 위한 방법 및 유전자형 분석 패널 |
| EP3783110B1 (en) * | 2009-11-05 | 2022-11-23 | The Chinese University Of Hong Kong | Fetal genomic analysis from a maternal biological sample |
| CA2780016C (en) | 2009-11-06 | 2017-09-19 | The Chinese University Of Hong Kong | Size-based genomic analysis |
| US9260745B2 (en) * | 2010-01-19 | 2016-02-16 | Verinata Health, Inc. | Detecting and classifying copy number variation |
| WO2011146632A1 (en) | 2010-05-18 | 2011-11-24 | Gene Security Network Inc. | Methods for non-invasive prenatal ploidy calling |
| US20120190020A1 (en) * | 2011-01-25 | 2012-07-26 | Aria Diagnostics, Inc. | Detection of genetic abnormalities |
| CA2827873C (en) * | 2011-02-24 | 2022-08-16 | The Chinese University Of Hong Kong | Molecular testing of multiple pregnancies |
| CN105121660B (zh) | 2013-03-15 | 2018-09-28 | 香港中文大学 | 确定多胎妊娠的胎儿基因组 |
-
2014
- 2014-03-17 CN CN201480012432.2A patent/CN105121660B/zh active Active
- 2014-03-17 EP EP14764129.4A patent/EP2971126B1/en not_active Not-in-force
- 2014-03-17 MX MX2015010785A patent/MX363345B/es unknown
- 2014-03-17 CA CA2901773A patent/CA2901773A1/en not_active Abandoned
- 2014-03-17 EP EP18194883.7A patent/EP3434790A1/en not_active Withdrawn
- 2014-03-17 WO PCT/CN2014/073506 patent/WO2014139477A1/en not_active Ceased
- 2014-03-17 JP JP2015561932A patent/JP2016518811A/ja active Pending
- 2014-03-17 EA EA201500939A patent/EA201500939A1/ru unknown
- 2014-03-17 KR KR1020157027071A patent/KR20150132216A/ko not_active Withdrawn
- 2014-03-17 AU AU2014231358A patent/AU2014231358A1/en not_active Abandoned
- 2014-03-17 TW TW103109991A patent/TWI637058B/zh active
- 2014-03-17 US US14/216,405 patent/US10106836B2/en not_active Expired - Fee Related
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