JP2016518811A - 多胎妊娠における胎児ゲノムの決定 - Google Patents

多胎妊娠における胎児ゲノムの決定 Download PDF

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Publication number
JP2016518811A
JP2016518811A JP2015561932A JP2015561932A JP2016518811A JP 2016518811 A JP2016518811 A JP 2016518811A JP 2015561932 A JP2015561932 A JP 2015561932A JP 2015561932 A JP2015561932 A JP 2015561932A JP 2016518811 A JP2016518811 A JP 2016518811A
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Prior art keywords
allele
fetuses
ratio
maternal
cutoff value
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JP2015561932A
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English (en)
Japanese (ja)
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JP2016518811A5 (enExample
Inventor
ユク ミン デニス ロー
ユク ミン デニス ロー
ロッサ ワイ クン チウ
ロッサ ワイ クン チウ
クワン チー チャン
クワン チー チャン
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Chinese University of Hong Kong CUHK
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Chinese University of Hong Kong CUHK
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Application filed by Chinese University of Hong Kong CUHK filed Critical Chinese University of Hong Kong CUHK
Publication of JP2016518811A publication Critical patent/JP2016518811A/ja
Publication of JP2016518811A5 publication Critical patent/JP2016518811A5/ja
Pending legal-status Critical Current

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B30/00—ICT specially adapted for sequence analysis involving nucleotides or amino acids
    • G16B30/10—Sequence alignment; Homology search
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/156—Polymorphic or mutational markers
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B30/00—ICT specially adapted for sequence analysis involving nucleotides or amino acids

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  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Pathology (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Evolutionary Biology (AREA)
  • Medical Informatics (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Theoretical Computer Science (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Management, Administration, Business Operations System, And Electronic Commerce (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
JP2015561932A 2013-03-15 2014-03-17 多胎妊娠における胎児ゲノムの決定 Pending JP2016518811A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201361789992P 2013-03-15 2013-03-15
US61/789,992 2013-03-15
PCT/CN2014/073506 WO2014139477A1 (en) 2013-03-15 2014-03-17 Determining fetal genomes for multiple fetus pregnancies

Publications (2)

Publication Number Publication Date
JP2016518811A true JP2016518811A (ja) 2016-06-30
JP2016518811A5 JP2016518811A5 (enExample) 2017-04-13

Family

ID=51535879

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2015561932A Pending JP2016518811A (ja) 2013-03-15 2014-03-17 多胎妊娠における胎児ゲノムの決定

Country Status (11)

Country Link
US (1) US10106836B2 (enExample)
EP (2) EP3434790A1 (enExample)
JP (1) JP2016518811A (enExample)
KR (1) KR20150132216A (enExample)
CN (1) CN105121660B (enExample)
AU (1) AU2014231358A1 (enExample)
CA (1) CA2901773A1 (enExample)
EA (1) EA201500939A1 (enExample)
MX (1) MX363345B (enExample)
TW (1) TWI637058B (enExample)
WO (1) WO2014139477A1 (enExample)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HUE061110T2 (hu) 2009-11-05 2023-05-28 Univ Hong Kong Chinese Magzati genomelemzés anyai biológiai mintából
EP2678451B1 (en) 2011-02-24 2017-04-26 The Chinese University Of Hong Kong Molecular testing of multiple pregnancies
AU2014231358A1 (en) 2013-03-15 2015-09-24 The Chinese University Of Hong Kong Determining fetal genomes for multiple fetus pregnancies
EP3739061B1 (en) 2015-07-20 2022-03-23 The Chinese University Of Hong Kong Methylation pattern analysis of haplotypes in tissues in dna mixture

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20130059733A1 (en) * 2011-02-24 2013-03-07 The Chinese University Of Hong Kong Molecular testing of multiple pregnancies

Family Cites Families (21)

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Publication number Priority date Publication date Assignee Title
GB9704444D0 (en) 1997-03-04 1997-04-23 Isis Innovation Non-invasive prenatal diagnosis
US6927028B2 (en) 2001-08-31 2005-08-09 Chinese University Of Hong Kong Non-invasive methods for detecting non-host DNA in a host using epigenetic differences between the host and non-host DNA
US7727720B2 (en) 2002-05-08 2010-06-01 Ravgen, Inc. Methods for detection of genetic disorders
EP1599608A4 (en) 2003-03-05 2007-07-18 Genetic Technologies Ltd Identification of fetal DNA and fetal cell marker in maternal plasma or serum
ATE435301T1 (de) 2003-10-16 2009-07-15 Sequenom Inc Nicht invasiver nachweis fötaler genetischer merkmale
US7645576B2 (en) 2005-03-18 2010-01-12 The Chinese University Of Hong Kong Method for the detection of chromosomal aneuploidies
US20070122823A1 (en) 2005-09-01 2007-05-31 Bianchi Diana W Amniotic fluid cell-free fetal DNA fragment size pattern for prenatal diagnosis
GB0523276D0 (en) 2005-11-15 2005-12-21 London Bridge Fertility Chromosomal analysis by molecular karyotyping
TR201910868T4 (tr) 2006-02-02 2019-08-21 Univ Leland Stanford Junior Dijital analizle invazif olmayan fetal genetik tarama.
WO2007100911A2 (en) 2006-02-28 2007-09-07 University Of Louisville Research Foundation Detecting fetal chromosomal abnormalities using tandem single nucleotide polymorphisms
EP2029779A4 (en) 2006-06-14 2010-01-20 Living Microsystems Inc HIGHLY PARALLEL SNP GENOTYPING UTILIZATION FOR FETAL DIAGNOSIS
EP3892736A1 (en) 2007-07-23 2021-10-13 The Chinese University of Hong Kong Determining a nucleic acid sequence imbalance
US12180549B2 (en) 2007-07-23 2024-12-31 The Chinese University Of Hong Kong Diagnosing fetal chromosomal aneuploidy using genomic sequencing
ES2620431T3 (es) 2008-08-04 2017-06-28 Natera, Inc. Métodos para la determinación de alelos y de ploidía
CA2748030A1 (en) 2008-12-22 2010-07-01 Arnold R. Oliphant Methods and genotyping panels for detecting alleles, genomes, and transcriptomes
HUE061110T2 (hu) 2009-11-05 2023-05-28 Univ Hong Kong Chinese Magzati genomelemzés anyai biológiai mintából
MX357692B (es) 2009-11-06 2018-07-19 Univ Hong Kong Chinese Analisis genomico a base de tamaño.
US9260745B2 (en) * 2010-01-19 2016-02-16 Verinata Health, Inc. Detecting and classifying copy number variation
CA3207599A1 (en) 2010-05-18 2011-11-24 Natera, Inc. Methods for non-invasive prenatal ploidy calling
WO2012103031A2 (en) * 2011-01-25 2012-08-02 Ariosa Diagnostics, Inc. Detection of genetic abnormalities
AU2014231358A1 (en) 2013-03-15 2015-09-24 The Chinese University Of Hong Kong Determining fetal genomes for multiple fetus pregnancies

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20130059733A1 (en) * 2011-02-24 2013-03-07 The Chinese University Of Hong Kong Molecular testing of multiple pregnancies

Also Published As

Publication number Publication date
EP2971126B1 (en) 2018-11-07
TWI637058B (zh) 2018-10-01
WO2014139477A1 (en) 2014-09-18
CN105121660B (zh) 2018-09-28
CA2901773A1 (en) 2014-09-18
CN105121660A (zh) 2015-12-02
MX2015010785A (es) 2015-11-26
US10106836B2 (en) 2018-10-23
EP2971126A4 (en) 2016-10-26
TW201441373A (zh) 2014-11-01
MX363345B (es) 2019-03-20
EA201500939A1 (ru) 2016-01-29
AU2014231358A1 (en) 2015-09-24
EP3434790A1 (en) 2019-01-30
KR20150132216A (ko) 2015-11-25
EP2971126A1 (en) 2016-01-20
US20140315200A1 (en) 2014-10-23

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