JP2016518321A5 - - Google Patents
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- Publication number
- JP2016518321A5 JP2016518321A5 JP2016501214A JP2016501214A JP2016518321A5 JP 2016518321 A5 JP2016518321 A5 JP 2016518321A5 JP 2016501214 A JP2016501214 A JP 2016501214A JP 2016501214 A JP2016501214 A JP 2016501214A JP 2016518321 A5 JP2016518321 A5 JP 2016518321A5
- Authority
- JP
- Japan
- Prior art keywords
- range
- rfviii
- formulation
- ppm
- present
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361799495P | 2013-03-15 | 2013-03-15 | |
| US61/799,495 | 2013-03-15 | ||
| US201361869191P | 2013-08-23 | 2013-08-23 | |
| US61/869,191 | 2013-08-23 | ||
| PCT/US2014/023357 WO2014150477A1 (en) | 2013-03-15 | 2014-03-11 | Recombinant factor viii formulations |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2016518321A JP2016518321A (ja) | 2016-06-23 |
| JP2016518321A5 true JP2016518321A5 (cg-RX-API-DMAC10.html) | 2017-04-13 |
Family
ID=51580768
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016501214A Pending JP2016518321A (ja) | 2013-03-15 | 2014-03-11 | 組み換え因子ｖｉｉｉ配合物 |
Country Status (17)
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2016115561A1 (en) * | 2015-01-18 | 2016-07-21 | Biogen Ma Inc. | Formulations and screening of biological therapeutic agents |
| CN108884145B (zh) | 2015-11-13 | 2023-08-22 | 武田药品工业株式会社 | 用于血友病a的基因治疗的具有增加的表达的编码重组fviii变体的病毒载体 |
| US12091675B2 (en) | 2018-07-16 | 2024-09-17 | Takeda Pharmaceutical Company Limited | Gene therapy of hemophilia a using viral vectors encoding recombinant FVIII variants with increased expression |
| TWI851647B (zh) | 2019-01-16 | 2024-08-11 | 日商武田藥品工業股份有限公司 | 用於a型血友病基因治療之編碼表現增加之重組fviii變異體的病毒載體 |
| WO2021032646A1 (en) * | 2019-08-16 | 2021-02-25 | Octapharma Ag | Stabilizing buffer for factor viii and vwf |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5763401A (en) * | 1996-07-12 | 1998-06-09 | Bayer Corporation | Stabilized albumin-free recombinant factor VIII preparation having a low sugar content |
| CN1339170A (zh) * | 1999-02-01 | 2002-03-06 | 日本电气硝子株式会社 | 阴极射线管及其制造方法 |
| EP1820516B1 (en) * | 1999-02-22 | 2013-07-24 | University of Connecticut | Novel albumin-free factor VIII formulations |
| EP1421539B1 (en) * | 2001-06-14 | 2009-10-28 | The Scripps Research Institute | Stabilized factor viii with engineered disulfide bonds |
| GB0207092D0 (en) * | 2002-03-26 | 2002-05-08 | Sod Conseils Rech Applic | Stable pharmaceutical composition containing factor VIII |
| DK2371856T3 (en) * | 2004-11-12 | 2022-08-08 | Bayer Healthcare Llc | Site-directed modifikation af FVIII |
| WO2007126808A1 (en) * | 2006-03-31 | 2007-11-08 | Baxter International Inc | Pegylated factor viii |
| EP2385825B1 (en) * | 2008-11-07 | 2018-10-10 | University of Connecticut | Factor viii formulations |
| CA2748662A1 (en) * | 2009-01-19 | 2010-07-22 | Bayer Healthcare Llc | Protein conjugate having an endopeptidase-cleavable bioprotective moiety |
-
2014
- 2014-03-11 AU AU2014237111A patent/AU2014237111B2/en not_active Ceased
- 2014-03-11 HK HK16101334.5A patent/HK1213273A1/zh unknown
- 2014-03-11 RU RU2015144076A patent/RU2015144076A/ru not_active Application Discontinuation
- 2014-03-11 BR BR112015022730A patent/BR112015022730A2/pt not_active IP Right Cessation
- 2014-03-11 JP JP2016501214A patent/JP2016518321A/ja active Pending
- 2014-03-11 WO PCT/US2014/023357 patent/WO2014150477A1/en not_active Ceased
- 2014-03-11 CN CN201480025467.XA patent/CN105209487A/zh active Pending
- 2014-03-11 MX MX2015012905A patent/MX2015012905A/es unknown
- 2014-03-11 SG SG10201803999UA patent/SG10201803999UA/en unknown
- 2014-03-11 US US14/774,191 patent/US20160030524A1/en not_active Abandoned
- 2014-03-11 EP EP14770228.6A patent/EP2970430A4/en not_active Withdrawn
- 2014-03-11 CA CA2905739A patent/CA2905739A1/en not_active Abandoned
- 2014-03-11 SG SG11201507618YA patent/SG11201507618YA/en unknown
- 2014-03-11 PE PE2015002012A patent/PE20160121A1/es not_active Application Discontinuation
- 2014-03-11 KR KR1020157029441A patent/KR20150132449A/ko not_active Withdrawn
- 2014-03-13 UY UY0001035412A patent/UY35412A/es not_active Application Discontinuation
- 2014-03-13 TW TW103109012A patent/TW201521761A/zh unknown
-
2015
- 2015-10-14 ZA ZA2015/07684A patent/ZA201507684B/en unknown
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