JP2016517849A5 - - Google Patents
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- Publication number
- JP2016517849A5 JP2016517849A5 JP2016507969A JP2016507969A JP2016517849A5 JP 2016517849 A5 JP2016517849 A5 JP 2016517849A5 JP 2016507969 A JP2016507969 A JP 2016507969A JP 2016507969 A JP2016507969 A JP 2016507969A JP 2016517849 A5 JP2016517849 A5 JP 2016517849A5
- Authority
- JP
- Japan
- Prior art keywords
- compound
- substituent
- formula
- carbon atoms
- ethylpyridine
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PCT/CN2013/074363 WO2014169462A1 (zh) | 2013-04-18 | 2013-04-18 | 具有抗癌活性的7-α-[9-(4,4,5,5,-五氟戊基亚硫酰基)壬基]-雌甾-1,3,5(10)-三烯-3,17β-二醇的酯类衍生物及其制备方法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2016517849A JP2016517849A (ja) | 2016-06-20 |
| JP2016517849A5 true JP2016517849A5 (https=) | 2017-03-09 |
| JP6356218B2 JP6356218B2 (ja) | 2018-07-11 |
Family
ID=51730699
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016507969A Expired - Fee Related JP6356218B2 (ja) | 2013-04-18 | 2013-04-18 | 抗腫瘍活性を有する７−α−［９−（４，４，５，５，５−ペンタフルオロペンチルスルフィニル）ノニル］−エストラ−１，３，５（１０）−トリエン−３，１７β−ジオールのエステル誘導体及びその調製方法 |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US20160060288A1 (https=) |
| EP (1) | EP2987799B1 (https=) |
| JP (1) | JP6356218B2 (https=) |
| KR (1) | KR102046415B1 (https=) |
| CN (1) | CN104936971B (https=) |
| AU (1) | AU2013386732B2 (https=) |
| CA (1) | CA2909418A1 (https=) |
| WO (1) | WO2014169462A1 (https=) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2014169456A1 (zh) * | 2013-04-18 | 2014-10-23 | 西安力邦医药科技有限责任公司 | 7-α-[9-(4,4,5,5,5-五氟戊基亚硫酰基)壬基]-雌甾-1,3,5(10)-三烯-3,17β-二醇及其衍生物的用途 |
| JP7384903B2 (ja) * | 2018-05-24 | 2023-11-21 | ケーアイ ファーマシューティカルズ，リミテッド・ライアビリティ・カンパニー | フルベストラントのプロドラッグ |
| EP4061376A4 (en) * | 2019-11-24 | 2024-03-13 | Kashiv Biosciences, LLC | Prodrugs of fulvestrant |
Family Cites Families (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NL7613248A (nl) * | 1976-11-26 | 1978-05-30 | Akzo Nv | Werkwijze voor het bereiden van nieuwe steroid- esters. |
| GB8327256D0 (en) * | 1983-10-12 | 1983-11-16 | Ici Plc | Steroid derivatives |
| US5183514A (en) | 1991-04-01 | 1993-02-02 | Texaco Chemical Company | Process for dissolving or removing rigid polyurethane foam by contacting with 1,2-dimethyl imidazole |
| DE4218743C2 (de) * | 1992-06-04 | 2001-10-25 | Schering Ag | Verfahren zur Herstellung C(7)-substituierter Estra-1,3,5(10)-triene sowie neue Ausgangsprodukte für dieses Verfahren |
| IL112778A0 (en) * | 1994-03-04 | 1995-05-26 | Merck & Co Inc | Substituted heterocycles, their preparation and pharmaceutical compositions containing them |
| DE19635525A1 (de) * | 1996-08-20 | 1998-02-26 | Schering Ag | 7alpha-(xi-Aminoalkyl)-estratriene, Verfahren zu deren Herstellung, pharmazeutische Präparate, die diese 7alpha(xi-Aminoalkyl-estratriene enthalten sowie deren Verwendung zur Herstellung von Arzneimitteln |
| AR015500A1 (es) * | 1997-12-23 | 2001-05-02 | Schering Ag | 11 BETA-HALoGENO-ESTRATRIENOS SUSTITUIDOS EN 7 ALFA, PROCEDIMIENTO PARA ELABORAR PREPARADOS FARMACEUTICOS QUE CONTIENEN TALES 11 BETA-HALOGENO-ESTRATRIENOSSUSTITUIDOS EN 7 ALFA, ASI COMO SU UTILIZACION EN LA ELABORACION DE MEDICAMENTOS. |
| GB0000313D0 (en) | 2000-01-10 | 2000-03-01 | Astrazeneca Uk Ltd | Formulation |
| JP2005524630A (ja) * | 2002-01-14 | 2005-08-18 | ノルディック・ビオサイエンス・エー／エス | エストロゲン受容体を介する軟骨破壊の抑制 |
| CN100395259C (zh) * | 2004-04-28 | 2008-06-18 | 江苏豪森药业股份有限公司 | 甾体类衍生物 |
| US7790910B2 (en) * | 2004-07-27 | 2010-09-07 | Sicor Inc. | Process for the preparation of 7α-alkylated 19-norsteroids |
| US10174070B2 (en) * | 2005-09-30 | 2019-01-08 | Endece Llc | 6-substituted estradiol derivatives and methods of use |
| JP5256042B2 (ja) * | 2005-11-22 | 2013-08-07 | インサイト・コーポレイション | 癌の処置のための併用療法 |
| JP2011514349A (ja) * | 2008-03-07 | 2011-05-06 | サイドース・エルエルシー | フルベストラント配合物 |
| CN102600073B (zh) * | 2012-03-31 | 2014-01-01 | 莱普德制药有限公司 | 以乳酸酯为基础的氟维司群或其衍生物油性制剂及其制备方法 |
| WO2014169456A1 (zh) * | 2013-04-18 | 2014-10-23 | 西安力邦医药科技有限责任公司 | 7-α-[9-(4,4,5,5,5-五氟戊基亚硫酰基)壬基]-雌甾-1,3,5(10)-三烯-3,17β-二醇及其衍生物的用途 |
| US9271990B2 (en) * | 2014-02-14 | 2016-03-01 | Fresenius Kabi Usa, Llc | Fulvestrant formulations |
-
2013
- 2013-04-18 US US14/781,650 patent/US20160060288A1/en not_active Abandoned
- 2013-04-18 WO PCT/CN2013/074363 patent/WO2014169462A1/zh not_active Ceased
- 2013-04-18 CA CA2909418A patent/CA2909418A1/en not_active Abandoned
- 2013-04-18 KR KR1020157033007A patent/KR102046415B1/ko not_active Expired - Fee Related
- 2013-04-18 EP EP13882193.9A patent/EP2987799B1/en active Active
- 2013-04-18 JP JP2016507969A patent/JP6356218B2/ja not_active Expired - Fee Related
- 2013-04-18 CN CN201380069374.2A patent/CN104936971B/zh active Active
- 2013-04-18 AU AU2013386732A patent/AU2013386732B2/en not_active Ceased
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